Published in Mol Ther on January 01, 2007
Antisense-mediated exon skipping: a versatile tool with therapeutic and research applications. RNA (2007) 1.78
Improved cell-penetrating peptide-PNA conjugates for splicing redirection in HeLa cells and exon skipping in mdx mouse muscle. Nucleic Acids Res (2008) 1.52
Guidelines for antisense oligonucleotide design and insight into splice-modulating mechanisms. Mol Ther (2008) 1.48
A novel morpholino oligomer targeting ISS-N1 improves rescue of severe spinal muscular atrophy transgenic mice. Hum Gene Ther (2013) 1.17
Antisense oligonucleotide induced exon skipping and the dystrophin gene transcript: cocktails and chemistries. BMC Mol Biol (2007) 1.11
Dynamics of co-transcriptional pre-mRNA folding influences the induction of dystrophin exon skipping by antisense oligonucleotides. PLoS One (2008) 1.09
Rational design of antisense oligomers to induce dystrophin exon skipping. Mol Ther (2009) 1.01
Improved antisense oligonucleotide design to suppress aberrant SMN2 gene transcript processing: towards a treatment for spinal muscular atrophy. PLoS One (2013) 1.00
Design of phosphorodiamidate morpholino oligomers (PMOs) for the induction of exon skipping of the human DMD gene. Mol Ther (2009) 0.98
Optimization of peptide nucleic acid antisense oligonucleotides for local and systemic dystrophin splice correction in the mdx mouse. Mol Ther (2010) 0.98
Antisense PMO found in dystrophic dog model was effective in cells from exon 7-deleted DMD patient. PLoS One (2010) 0.92
Progress toward therapy with antisense-mediated splicing modulation. Curr Opin Mol Ther (2009) 0.91
A prospective study in the rational design of efficient antisense oligonucleotides for exon skipping in the DMD gene. Hum Gene Ther (2012) 0.86
Targeted exon skipping to address "leaky" mutations in the dystrophin gene. Mol Ther Nucleic Acids (2012) 0.84
In silico screening based on predictive algorithms as a design tool for exon skipping oligonucleotides in Duchenne muscular dystrophy. PLoS One (2015) 0.83
Personalized exon skipping strategies to address clustered non-deletion dystrophin mutations. Neuromuscul Disord (2010) 0.83
Mismatched single stranded antisense oligonucleotides can induce efficient dystrophin splice switching. BMC Med Genet (2011) 0.80
Targeted exon skipping to correct exon duplications in the dystrophin gene. Mol Ther Nucleic Acids (2014) 0.79
Antisense suppression of donor splice site mutations in the dystrophin gene transcript. Mol Genet Genomic Med (2013) 0.79
Detection of internal exon deletion with exon Del. BMC Bioinformatics (2014) 0.79
Deletion of Dystrophin In-Frame Exon 5 Leads to a Severe Phenotype: Guidance for Exon Skipping Strategies. PLoS One (2016) 0.78
Investigation of splicing changes and post-translational processing of LMNA in sporadic inclusion body myositis. Int J Clin Exp Pathol (2013) 0.76
Novel compounds for the treatment of Duchenne muscular dystrophy: emerging therapeutic agents. Appl Clin Genet (2011) 0.75
Discovery of Influenza A Virus Sequence Pairs and Their Combinations for Simultaneous Heterosubtypic Targeting that Hedge against Antiviral Resistance. PLoS Comput Biol (2016) 0.75
Correcting the NLRP3 inflammasome deficiency in macrophages from autoimmune NZB mice with exon skipping antisense oligonucleotides. Immunol Cell Biol (2016) 0.75
An amphipathic trans-acting phosphorothioate DNA element delivers uncharged PNA and PMO nucleic acid sequences in mammalian cells. Curr Protoc Nucleic Acid Chem (2016) 0.75
Antisense oligonucleotide induction of progerin in human myogenic cells. PLoS One (2014) 0.75
Investigating Synthetic Oligonucleotide Targeting of Mir31 in Duchenne Muscular Dystrophy. PLoS Curr (2016) 0.75
HA117 endows HL60 cells with a stem-like signature by inhibiting the degradation of DNMT1 via its ability to down-regulate expression of the GGL domain of RGS6. PLoS One (2017) 0.75
Long-term outcome after intravenous magnesium sulphate in suspected acute myocardial infarction: the second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2) Lancet (1994) 8.63
Retracted First myocardial infarction in patients of Indian subcontinent and European origin: comparison of risk factors, management, and long term outcome. BMJ (1997) 4.24
Use of polymerase chain reaction for rapid diagnosis of tuberculosis. J Clin Microbiol (1992) 3.73
Intravenous magnesium sulphate in suspected acute myocardial infarction: results of the second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2) Lancet (1992) 3.40
Antisense-induced exon skipping and synthesis of dystrophin in the mdx mouse. Proc Natl Acad Sci U S A (2001) 2.71
A mutation in the alpha tropomyosin gene TPM3 associated with autosomal dominant nemaline myopathy. Nat Genet (1995) 2.57
Arterial versus capillary sampling for analysing blood gas pressures. BMJ (1995) 2.55
Mutations in the nebulin gene associated with autosomal recessive nemaline myopathy. Proc Natl Acad Sci U S A (1999) 2.27
Massive idiosyncratic exon skipping corrects the nonsense mutation in dystrophic mouse muscle and produces functional revertant fibers by clonal expansion. J Cell Biol (2000) 2.24
Older adults and withdrawal from benzodiazepine hypnotics in general practice: effects on cognitive function, sleep, mood and quality of life. Psychol Med (2003) 2.17
Antisense oligonucleotide-induced exon skipping restores dystrophin expression in vitro in a canine model of DMD. Gene Ther (2006) 2.00
Acute small-bowel obstruction following mesenteric perforation by CAPD catheter. Nephrol Dial Transplant (1997) 1.85
Specific removal of the nonsense mutation from the mdx dystrophin mRNA using antisense oligonucleotides. Neuromuscul Disord (1999) 1.83
Humoral and cellular immune responses up to 7.5 years after administration of streptokinase for acute myocardial infarction. Eur Heart J (1999) 1.64
Comparative analysis of antisense oligonucleotide sequences for targeted skipping of exon 51 during dystrophin pre-mRNA splicing in human muscle. Hum Gene Ther (2007) 1.63
Gene mapping in Gypsies identifies a novel demyelinating neuropathy on chromosome 8q24. Nat Genet (1996) 1.61
Use of DNA amplification for the rapid identification of Mycobacterium bovis. Vet Microbiol (1991) 1.52
Comparative pharmacology of epibatidine: a potent agonist for neuronal nicotinic acetylcholine receptors. Mol Pharmacol (1995) 1.49
Bilateral retinopathy, aplastic anaemia, and central nervous system abnormalities: a new syndrome? J Med Genet (1992) 1.40
Half a loaf is better than waiting for the bread truck. A computerized mini-medical record for outpatient care. Arch Intern Med (1992) 1.39
Extracorporeal whole body hyperthermia treatment of HIV patients, a feasibility study. Int J Hyperthermia (1998) 1.38
Histopathology of papilloma virus infection of the cervix uteri: the history, taxonomy, nomenclature and reporting of koilocytic dysplasias. J Clin Pathol (1983) 1.23
Autosomal dominant distal myopathy: linkage to chromosome 14. Am J Hum Genet (1995) 1.22
[3H]L-655,708, a novel ligand selective for the benzodiazepine site of GABAA receptors which contain the alpha 5 subunit. Neuropharmacology (1996) 1.21
Cell-penetrating peptide-morpholino conjugates alter pre-mRNA splicing of DMD (Duchenne muscular dystrophy) and inhibit murine coronavirus replication in vivo. Biochem Soc Trans (2007) 1.17
Translation of chick aortic elastin messenger ribonucleic acid. Comparison to elastin synthesis in chick aorta organ culture. Biochemistry (1980) 1.16
Homozygosity for a nonsense mutation in the alpha-tropomyosin slow gene TPM3 in a patient with severe infantile nemaline myopathy. Neuromuscul Disord (1999) 1.10
Attitudes to long-term use of benzodiazepine hypnotics by older people in general practice: findings from interviews with service users and providers. Aging Ment Health (2004) 1.10
Mutation segregation and rapid carrier detection of X-linked muscular dystrophy in dogs. Am J Vet Res (1996) 1.09
Neuropeptides modulate immune deviation induced via the anterior chamber of the eye. J Immunol (1995) 1.08
Somatic colocalization of rat SK1 and D class (Ca(v)1.2) L-type calcium channels in rat CA1 hippocampal pyramidal neurons. J Neurosci (2001) 1.07
Strokes in the elderly - higher acute and 3-month mortality - an explanation. Cerebrovasc Dis (1999) 1.06
A mutation in the alpha tropomyosin gene TPM3 associated with autosomal dominant nemaline myopathy NEM1. Nat Genet (1995) 1.05
Use of the dog model for Duchenne muscular dystrophy in gene therapy trials. Neuromuscul Disord (1997) 1.03
Alternative dystrophin gene transcripts in golden retriever muscular dystrophy. Muscle Nerve (1998) 1.01
Molecular analysis of a spontaneous dystrophin 'knockout' dog. Neuromuscul Disord (1999) 1.00
Novel mutation in the myelin protein zero gene in a family with intermediate hereditary motor and sensory neuropathy. J Neurol Neurosurg Psychiatry (1999) 0.99
The regrowth of axons within tissue defects in the CNS is promoted by implanted hydrogel matrices that contain BDNF and CNTF producing fibroblasts. Exp Neurol (2001) 0.99
Induced dystrophin exon skipping in human muscle explants. Neuromuscul Disord (2006) 0.98
Evaluation and optimization of the new EBT2 radiochromic film dosimetry system for patient dose verification in radiotherapy. Phys Med Biol (2010) 0.98
High-level dystrophin expression after adenovirus-mediated dystrophin minigene transfer to skeletal muscle of dystrophic dogs: prolongation of expression with immunosuppression. Hum Gene Ther (1998) 0.96
What influences outcome of stroke--pyrexia or dysphagia? Int J Clin Pract (2001) 0.92
Development of a snapback method of single-strand conformation polymorphism analysis for genotyping Golden Retrievers for the X-linked muscular dystrophy allele. Am J Vet Res (1999) 0.91
Study of a passive haemagglutination test for gonorrhoea. Br J Vener Dis (1973) 0.91
Apolipoprotein-E genotyping in diagnosis of Alzheimer's disease. Lancet (1996) 0.90
Nocturnal intermittent peritoneal dialysis. Nephrol Dial Transplant (1994) 0.89
A comparison of genomic coding sequences for feather and scale keratins: structural and evolutionary implications. EMBO J (1984) 0.89
Quantitation of muscle precursor cell activity in skeletal muscle by Northern analysis of MyoD and myogenin expression: Application to dystrophic (mdx) mouse muscle. Mol Cell Neurosci (1992) 0.88
An immunohistological study of spontaneous regression of condylomata acuminata. Genitourin Med (1990) 0.88
Enhanced in vivo delivery of antisense oligonucleotides to restore dystrophin expression in adult mdx mouse muscle. FEBS Lett (2003) 0.88
Is warfarin a contraindication to thrombolysis in acute ST elevation myocardial infarction? Heart (2006) 0.88
A splice-site mutation causing ovine McArdle's disease. Neuromuscul Disord (1997) 0.87
Alternate Pax7 transcripts are expressed specifically in skeletal muscle, brain and other organs of adult mice. Int J Biochem Cell Biol (1997) 0.86
A (CA)n repeat polymorphism for the human skeletal muscle alpha-actinin gene ACTN2 and its localization on the linkage map of chromosome 1. Genomics (1992) 0.86
On the nature of the deep cellular disturbances in human-papilloma-virus infection of the squamous cervical epithelium. Lancet (1983) 0.85
Elastin biosynthesis in chick embryonic lung tissue. Comparison to chick aortic elastin. Biochemistry (1981) 0.85
Snapback SSCP analysis: engineered conformation changes for the rapid typing of known mutations. Hum Mutat (1998) 0.84
Randomised trial comparing prednimustine with combination chemotherapy in advanced ovarian carcinoma. Cancer Chemother Pharmacol (1989) 0.84
Dystrophin expression in muscle following gene transfer with a fully deleted ("gutted") adenovirus is markedly improved by trans-acting adenoviral gene products. Hum Gene Ther (2001) 0.84
Three novel mutations and two variants in the gene for Cu/Zn superoxide dismutase in familial amyotrophic lateral sclerosis. Neuromuscul Disord (1996) 0.82
Management of myocardial infarction in the elderly: admission and outcome on a coronary care unit. Health Trends (1992) 0.82
Cryptic splicing involving the splice site mutation in the canine model of Duchenne muscular dystrophy. Neuromuscul Disord (2001) 0.82
End-stage renal disease and erectile dysfunction. Is there any hope? Nephrol Dial Transplant (2000) 0.82
Histopathology and medical laboratory scientific officers. BMJ (1994) 0.81
Prolonged outbreak of meticillin-resistant Staphylococcus aureus in a cardiac surgery unit linked to a single colonized healthcare worker. J Hosp Infect (2013) 0.81
Photomutagenicity assays in bacteria: factors affecting assay design and assessment of photomutagenic potential of para-aminobenzoic acid. Mutagenesis (1994) 0.81
Plasma ferritin in acute hepatocellular damage. Clin Chem (2000) 0.81
Headache as a sign of phaeochromocytoma. Emerg Med J (2009) 0.81
Mapping Rph20: a gene conferring adult plant resistance to Puccinia hordei in barley. Theor Appl Genet (2011) 0.80
Immunological study of condylomata acuminata in men infected with the human immunodeficiency virus. Int J STD AIDS (1990) 0.80
Breast cancer screening in women aged under 50. BMJ (1997) 0.80
The spread of transgene expression at the site of gene construct injection. Muscle Nerve (2001) 0.80
Variation in the methylation profile and structure of Pax3 and Pax7 among different mouse strains and during expression. Gene (1997) 0.80
Co-regulation of survival of motor neuron and Bcl-xL expression: implications for neuroprotection in spinal muscular atrophy. Neuroscience (2012) 0.80
An immunohistological study of condylomata acuminata. Histopathology (1990) 0.79
Gene expression in clonally derived cell lines produced by in vitro transformation of rat fetal hepatocytes: isolation of cell lines which retain liver-specific markers. Cancer Res (1990) 0.79
Gene therapy and molecular approaches to the treatment of hereditary muscular disorders. Curr Opin Neurol (2000) 0.79
Is the incidence of trichomycosis of genital hair underestimated? J Am Acad Dermatol (1991) 0.78
Dietary supplementation with different vitamin C doses: no effect on oxidative DNA damage in healthy people. Eur J Nutr (2005) 0.78
Effects of oral propylthiouracil treatment on nitric oxide production in rat aorta. Br J Pharmacol (1999) 0.78
Insertion/deletion polymorphism in the angiotensin-converting enzyme gene and risk of and prognosis after myocardial infarction. J Am Coll Cardiol (1996) 0.78
Mesangiocapillary glomerulonephritis associated with ulcerative colitis: case reports of two patients. Nephrol Dial Transplant (1995) 0.78
Direct dystrophin and reporter gene transfer into dog muscle in vivo. Muscle Nerve (1998) 0.78
Pax7 includes two polymorphic homeoboxes which contain rearrangements associated with differences in the ability to regenerate damaged skeletal muscle in adult mice. Int J Biochem Cell Biol (1998) 0.78
Towards more drug-like proteomimetics: two-faced, synthetic α-helix mimetics based on a purine scaffold. Org Biomol Chem (2015) 0.78
Assignment of the human skeletal muscle alpha actin gene (ACTA1) to 1q42 by fluorescence in situ hybridisation. Cytogenet Cell Genet (1994) 0.77
Mycotic aneurysm of the aorta as a complication of Bacillus Calmette-Guérin instillation. J R Coll Physicians Edinb (2011) 0.77