Published in Org Lett on December 21, 2006
Formation and stability of a vinyl carbanion at the active site of orotidine 5'-monophosphate decarboxylase: pKa of the C-6 proton of enzyme-bound UMP. J Am Chem Soc (2008) 1.85
Carbanions from decarboxylation of orotate analogs: stability and mechanistic implications. Bioorg Chem (2007) 1.15
Convenient synthesis of N1-substituted orotic acid derivatives. Tetrahedron Lett (2014) 1.10
Accelerated hydrolysis of α-halo and α-cyano pyridinium relative to uracil derivatives: a model for ODCase-catalyzed hydrolysis of 6-cyanoUMP. Tetrahedron Lett (2011) 1.06
Proton transfer from C-6 of uridine 5'-monophosphate catalyzed by orotidine 5'-monophosphate decarboxylase: formation and stability of a vinyl carbanion intermediate and the effect of a 5-fluoro substituent. J Am Chem Soc (2012) 0.99
Hydrolysis of α-chloro-substituted 2- and 4-pyridones: rate enhancement by zwitterionic structure. Bioorg Med Chem Lett (2011) 0.93
Polarization in the structures of uracil and thiouracils: Implication for binding with orotidine 5'-monophosphate decarboxylase. Bioorg Med Chem Lett (2011) 0.89
Role of a guanidinium cation-phosphodianion pair in stabilizing the vinyl carbanion intermediate of orotidine 5'-phosphate decarboxylase-catalyzed reactions. Biochemistry (2013) 0.89
Stabilities of Uracil and Pyridone-Based Carbanions: A Systematic Study in the Gas Phase and Solution and Implications for the Mechanism of Orotidine-5'-Monophosphate Decarboxylase. Tetrahedron (2013) 0.87
The stability of aryl carbanions derived from pyridine N-oxide: the role of resonance in stabilizing aryl anions. J Am Chem Soc (2010) 0.84
Improved synthesis of N1-substituted orotic acid derivatives. Tetrahedron Lett (2013) 0.81
Substrate distortion contributes to the catalysis of orotidine 5'-monophosphate decarboxylase. J Am Chem Soc (2013) 0.79
A proficient enzyme. Science (1995) 5.02
A proficient enzyme revisited: the predicted mechanism for orotidine monophosphate decarboxylase. Science (1997) 1.99
Mechanism of decarboxylation of 1,3-dimethylorotic acid. A model for orotidine 5'-phosphate decarboxylase. J Am Chem Soc (1976) 1.80
The mechanism of orotidine 5'-monophosphate decarboxylase: catalysis by destabilization of the substrate. Biochemistry (2000) 1.57
Equilibrium of formation of the 6-carbanion of UMP, a potential intermediate in the action of OMP decarboxylase. J Am Chem Soc (2002) 1.50
Formation and stability of peptide enolates in aqueous solution. J Am Chem Soc (2002) 1.22
Accelerated decarboxylation of 1,3-dimethylorotic acid in ionic liquid. Bioorg Chem (2006) 1.22
Modest catalysis of the decarboxylation of orotate by hydrogen bonding: a theoretical model for orotidine- 5' -monophosphate decarboxylase. Bioorg Chem (2004) 1.13
Base-catalyzed reactions of 1,3-disubstituted uracils. J Org Chem (1977) 0.93
Convenient oxidation of benzylic and allylic halides to aldehydes and ketones. Tetrahedron Lett (2008) 2.13
Surprisingly low aqueous acidity at the alpha-positions of pyridiniums and pyrimidinium: the role of solvation. Org Lett (2008) 1.76
Excellent correlation between substituent constants and pyridinium N-methyl chemical shifts. Tetrahedron Lett (2009) 1.68
Amyloid-binding small molecules efficiently block SEVI (semen-derived enhancer of virus infection)- and semen-mediated enhancement of HIV-1 infection. J Biol Chem (2010) 1.26
Accelerated decarboxylation of 1,3-dimethylorotic acid in ionic liquid. Bioorg Chem (2006) 1.22
Kinetic analysis of the 4-methylideneimidazole-5-one-containing tyrosine aminomutase in enediyne antitumor antibiotic C-1027 biosynthesis. Biochemistry (2003) 1.16
Carbanions from decarboxylation of orotate analogs: stability and mechanistic implications. Bioorg Chem (2007) 1.15
Modest catalysis of the decarboxylation of orotate by hydrogen bonding: a theoretical model for orotidine- 5' -monophosphate decarboxylase. Bioorg Chem (2004) 1.13
Transcriptome analysis of rice root heterosis by RNA-Seq. BMC Genomics (2013) 1.12
Accelerated hydrolysis of α-halo and α-cyano pyridinium relative to uracil derivatives: a model for ODCase-catalyzed hydrolysis of 6-cyanoUMP. Tetrahedron Lett (2011) 1.06
Rational design of amyloid binding agents based on the molecular rotor motif. ChemMedChem (2010) 1.01
Proton transfer from C-6 of uridine 5'-monophosphate catalyzed by orotidine 5'-monophosphate decarboxylase: formation and stability of a vinyl carbanion intermediate and the effect of a 5-fluoro substituent. J Am Chem Soc (2012) 0.99
ANCA: A Family of Fluorescent Probes that Bind and Stain Amyloid Plaques in Human Tissue. ACS Chem Neurosci (2011) 0.95
Hydrolysis of α-chloro-substituted 2- and 4-pyridones: rate enhancement by zwitterionic structure. Bioorg Med Chem Lett (2011) 0.93
Polarization in the structures of uracil and thiouracils: Implication for binding with orotidine 5'-monophosphate decarboxylase. Bioorg Med Chem Lett (2011) 0.89
Substantial formation of hydrates and hemiacetals from pyridinium ketones. Tetrahedron Lett (2009) 0.88
Stabilities of Uracil and Pyridone-Based Carbanions: A Systematic Study in the Gas Phase and Solution and Implications for the Mechanism of Orotidine-5'-Monophosphate Decarboxylase. Tetrahedron (2013) 0.87
A tetra(ethylene glycol) derivative of benzothiazole aniline enhances Ras-mediated spinogenesis. J Neurosci (2013) 0.85
Identification of transcriptome SNPs for assessing allele-specific gene expression in a super-hybrid rice Xieyou9308. PLoS One (2013) 0.84
The stability of aryl carbanions derived from pyridine N-oxide: the role of resonance in stabilizing aryl anions. J Am Chem Soc (2010) 0.84
Kinetic and biochemical analysis of the mechanism of action of lysine 5,6-aminomutase. Arch Biochem Biophys (2003) 0.83
Identification of qRL7, a major quantitative trait locus associated with rice root length in hydroponic conditions. Breed Sci (2013) 0.82
One-dimensional CdS/TiO2 nanofiber composites as efficient visible-light-driven photocatalysts for selective organic transformation: synthesis, characterization, and performance. Langmuir (2015) 0.81
Catalysis of decarboxylation by an adjacent negative charge: a theoretical approach. Bioorg Chem (2003) 0.81
Multifunctional NH2-mediated zirconium metal-organic framework as an efficient visible-light-driven photocatalyst for selective oxidation of alcohols and reduction of aqueous Cr(VI). Dalton Trans (2013) 0.81
The element effect revisited: factors determining leaving group ability in activated nucleophilic aromatic substitution reactions. J Org Chem (2012) 0.81
Improved synthesis of N1-substituted orotic acid derivatives. Tetrahedron Lett (2013) 0.81
Unusual reaction of beta-hydroxy alpha-diazo carbonyl compounds with Cl3CCN/NaH and Rh(II)-catalyzed reaction of beta-trichloroacetylamino alpha-diazo carbonyl compounds. Org Lett (2003) 0.80
Highly dispersed palladium nanoparticles anchored on UiO-66(NH₂) metal-organic framework as a reusable and dual functional visible-light-driven photocatalyst. Nanoscale (2013) 0.79
Mechanism of rhodium-catalyzed carbene formation from diazo compounds. Org Lett (2007) 0.79
Enhanced photocatalytic hydrogen production activity via dual modification of MOF and reduced graphene oxide on CdS. Chem Commun (Camb) (2014) 0.76
Reactivity in the nucleophilic aromatic substitution reactions of pyridinium ions. Org Biomol Chem (2014) 0.75
Convenient one-pot synthesis of trans-1,2-diaryloxiranes from the direct coupling of benzyl halides. Tetrahedron Lett (2010) 0.75
A TaON nano-photocatalyst with low surface reduction defects for effective mineralization of chlorophenols under visible light irradiation. Phys Chem Chem Phys (2013) 0.75
Facile and rapid synthesis of pyrochlore W2O6 x H2O nanoplate via a fluorinion-assisted hydrothermal process. J Nanosci Nanotechnol (2014) 0.75
Template-free synthesis of a CdSnO3·3H2O hollow-nanocuboid photocatalyst via a facile microwave hydrothermal method. Nanotechnology (2013) 0.75