PubRank

A W Langerak

Author PubWeight™ 65.98‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Design and standardization of PCR primers and protocols for detection of clonal immunoglobulin and T-cell receptor gene recombinations in suspect lymphoproliferations: report of the BIOMED-2 Concerted Action BMH4-CT98-3936. Leukemia 2003 13.41
2 Standardized RT-PCR analysis of fusion gene transcripts from chromosome aberrations in acute leukemia for detection of minimal residual disease. Report of the BIOMED-1 Concerted Action: investigation of minimal residual disease in acute leukemia. Leukemia 1999 4.09
3 E2A and EBF act in synergy with the V(D)J recombinase to generate a diverse immunoglobulin repertoire in nonlymphoid cells. Mol Cell 2000 1.99
4 EuroFlow antibody panels for standardized n-dimensional flow cytometric immunophenotyping of normal, reactive and malignant leukocytes. Leukemia 2012 1.93
5 Improved reliability of lymphoma diagnostics via PCR-based clonality testing: report of the BIOMED-2 Concerted Action BHM4-CT98-3936. Leukemia 2006 1.72
6 Flow cytometric analysis of the Vbeta repertoire in healthy controls. Cytometry 2000 1.66
7 Powerful strategy for polymerase chain reaction-based clonality assessment in T-cell malignancies Report of the BIOMED-2 Concerted Action BHM4 CT98-3936. Leukemia 2006 1.62
8 CALM-AF10+ T-ALL expression profiles are characterized by overexpression of HOXA and BMI1 oncogenes. Leukemia 2005 1.59
9 Estimating human age from T-cell DNA rearrangements. Curr Biol 2010 1.58
10 Disruption of the BCL11B gene through inv(14)(q11.2q32.31) results in the expression of BCL11B-TRDC fusion transcripts and is associated with the absence of wild-type BCL11B transcripts in T-ALL. Leukemia 2005 1.39
11 Prognostic significance of molecular-cytogenetic abnormalities in pediatric T-ALL is not explained by immunophenotypic differences. Leukemia 2007 1.36
12 Distinct patterns of novel gene mutations in poor-prognostic stereotyped subsets of chronic lymphocytic leukemia: the case of SF3B1 and subset #2. Leukemia 2013 1.31
13 Chemoimmunotherapy with GA101 plus chlorambucil in patients with chronic lymphocytic leukemia and comorbidity: results of the CLL11 (BO21004) safety run-in. Leukemia 2012 1.13
14 Transcriptional control of t lymphocyte differentiation. Stem Cells 2001 1.12
15 TCRgammadelta+ large granular lymphocyte leukemias reflect the spectrum of normal antigen-selected TCRgammadelta+ T-cells. Leukemia 2006 1.11
16 Comparison of different polymerase chain reaction-based approaches for clonality assessment of immunoglobulin heavy-chain gene rearrangements in B-cell neoplasia. Mod Pathol 1999 1.05
17 17p13/TP53 deletion in B-CLL patients is associated with microRNA-34a downregulation. Leukemia 2008 1.05
18 DNA microarrays for comparison of gene expression profiles between diagnosis and relapse in precursor-B acute lymphoblastic leukemia: choice of technique and purification influence the identification of potential diagnostic markers. Leukemia 2003 1.03
19 Ordered recombination of immunoglobulin light chain genes occurs at the IGK locus but seems less strict at the IGL locus. Blood 2001 0.98
20 Ig heavy chain gene rearrangements in T-cell acute lymphoblastic leukemia exhibit predominant DH6-19 and DH7-27 gene usage, can result in complete V-D-J rearrangements, and are rare in T-cell receptor alpha beta lineage. Blood 1999 0.97
21 T cell receptor gamma (TCRG) gene rearrangements in T cell acute lymphoblastic leukemia refelct 'end-stage' recombinations: implications for minimal residual disease monitoring. Leukemia 2000 0.97
22 Molecular features responsible for the absence of immunoglobulin heavy chain protein synthesis in an IgH(-) subgroup of multiple myeloma. Blood 2000 0.94
23 A novel chronic lymphocytic leukemia subset expressing mutated IGHV3-7-encoded rheumatoid factor B-cell receptors that are functionally proficient. Leukemia 2012 0.94
24 Validation of BIOMED-2 multiplex PCR tubes for detection of TCRB gene rearrangements in T-cell malignancies. Leukemia 2004 0.91
25 Split-signal FISH for detection of chromosome aberrations in acute lymphoblastic leukemia. Leukemia 2004 0.89
26 Rapid and sensitive detection of all types of MLL gene translocations with a single FISH probe set. Leukemia 1999 0.88
27 Immunoglobulin and T cell receptor gene rearrangement patterns in acute lymphoblastic leukemia are less mature in adults than in children: implications for selection of PCR targets for detection of minimal residual disease. Leukemia 1998 0.88
28 Heteroduplex analysis of VDJ amplified segments from rearranged IgH genes for clonality assessments in B-cell non-Hodgkin's lymphoma. A comparison between different strategies. Haematologica 1999 0.86
29 DNA methylation pattern is altered in childhood T-cell acute lymphoblastic leukemia patients as compared with normal thymic subsets: insights into CpG island methylator phenotype in T-ALL. Leukemia 2011 0.86
30 Heteroduplex PCR analysis of rearranged immunoglobulin genes for clonality assessment in multiple myeloma. Haematologica 1999 0.86
31 Human T-cell lines with well-defined T-cell receptor gene rearrangements as controls for the BIOMED-2 multiplex polymerase chain reaction tubes. Leukemia 2006 0.84
32 Notch induces human T-cell receptor γδ+ thymocytes to differentiate along a parallel, highly proliferative and bipotent CD4 CD8 double-positive pathway. Leukemia 2011 0.83
33 Cytomegalovirus contributes partly to uraemia-associated premature immunological ageing of the T cell compartment. Clin Exp Immunol 2013 0.83
34 Fusion gene transcripts and Ig/TCR gene rearrangements are complementary but infrequent targets for PCR-based detection of minimal residual disease in acute myeloid leukemia. Leukemia 2002 0.83
35 A restricted clonal T-cell receptor αβ repertoire in Sézary syndrome is indicative of superantigenic stimulation. Br J Dermatol 2011 0.83
36 Human ovarian tumors of epithelial origin express PDGF in vitro and in vivo. Cancer Genet Cytogenet 1994 0.82
37 Malignant pleural mesothelioma. Crit Rev Oncol Hematol 1997 0.82
38 Biased Iglambda expression in hypermutated IgD multiple myelomas does not result from receptor revision. Leukemia 2002 0.82
39 Easy detection of all T cell receptor gamma (TCRG) gene rearrangements by Southern blot analysis: recommendations for optimal results. Leukemia 1999 0.81
40 Autoimmune lymphoproliferative syndrome (ALPS) in a child from consanguineous parents: a dominant or recessive disease? Pediatr Res 2000 0.81
41 Unique morphological spectrum of lymphomas in Nijmegen breakage syndrome (NBS) patients with high frequency of consecutive lymphoma formation. J Pathol 2008 0.80
42 Two consecutive immunophenotypic switches in a child with immunogenotypically stable acute leukaemia. Br J Haematol 2001 0.80
43 T-cell receptor Vbeta CDR3 oligoclonality frequently occurs in childhood refractory cytopenia (MDS-RC) and severe aplastic anemia. Leukemia 2008 0.80
44 Unusual immunoglobulin and T-cell receptor gene rearrangement patterns in acute lymphoblastic leukemias. Curr Top Microbiol Immunol 1999 0.79
45 Hydrocortisone-induced increase of PDGF beta-receptor expression in a human malignant mesothelioma cell line. Exp Cell Res 1992 0.79
46 Identification of regulatory sequences in the promoter of the PDGF B-chain gene in malignant mesothelioma cell lines. Biochim Biophys Acta 1996 0.79
47 Clonal T- and natural killer-cell large granular lymphocyte proliferations in a single patient established by array-based comparative genomic hybridization analysis. Leukemia 2006 0.77
48 Secondary T-acute lymphoblastic leukaemia mimicking blast crisis in chronic myeloid leukaemia. Br J Haematol 1999 0.77
49 Immunoglobulin light chain gene rearrangements display hierarchy in absence of selection for functionality in precursor-B-ALL. Leukemia 2002 0.76
50 Split-signal FISH for detection of chromosome aberrations. Hematology 2005 0.75
51 Lymphoma with multi-gene rearrangement on the level of immunoglobulin heavy chain, light chain, and T-cell receptor beta chain. Am J Hematol 1998 0.75
52 BMI1 as oncogenic candidate in a novel TCRB-associated chromosomal aberration in a patient with TCRgammadelta+ T-cell acute lymphoblastic leukemia. Leukemia 2007 0.75
53 Molecular discrimination between relapsed and secondary acute lymphoblastic leukemia: proposal for an easy strategy. Med Pediatr Oncol 2001 0.75
54 The presence of somatic mutations in immunoglobulin genes of B cell acute lymphoblastic leukemia (ALL-L3) supports assignment as Burkitt's leukemia-lymphoma rather than B-lineage ALL. Leukemia 2001 0.75
55 Low frequency of reverse transcription polymerase chain reaction-detectable chromosome aberrations in relapsed acute myeloid leukaemia: implications for detection of minimal residual disease. Br J Haematol 2001 0.75
56 Immunoglobulin lambda isotype gene rearrangements in B cell malignancies. Leukemia 2001 0.75
57 Enteropathy-associated T-cell lymphoma presenting with eosinophilia. Neth J Med 2003 0.75
58 Clearance of maternal leukaemic cells in a neonate. Br J Haematol 2001 0.75
59 A single split-signal FISH probe set allows detection of TAL1 translocations as well as SIL-TAL1 fusion genes in a single test. Leukemia 2002 0.75
60 Clonality analysis for antigen receptor genes: preliminary results from the Biomed-2 concerted action PL 96-3936. Hum Pathol 2003 0.75
61 Detection of clonal EBV episomes in lymphoproliferations as a diagnostic tool. Leukemia 2002 0.75