Financial anatomy of neuroscience research.

NIH disease funding levels and burden of disease. PLoS One (2011) 2.56

Can literature analysis identify innovation drivers in drug discovery? Nat Rev Drug Discov (2009) 1.57

Financing of U.S. biomedical research and new drug approvals across therapeutic areas. PLoS One (2009) 1.55

What should be done to improve the productivity of neurological research? Ann Neurol (2006) 1.25

Using ontology-based annotation to profile disease research. J Am Med Inform Assoc (2012) 0.94

Where will the (New) Drugs for Traumatic Brain Injury Treatment be Coming From? Front Neurol (2012) 0.88

Collaborative models for translational neuroscience and rehabilitation research. Neurorehabil Neural Repair (2009) 0.86

Barriers to investigator-initiated deep brain stimulation and device research. Neurology (2014) 0.80

National Institutes of Health: the lottery. Ann Neurol (2007) 0.75

Results availability for analgesic device, complex regional pain syndrome, and post-stroke pain trials: comparing the RReADS, RReACT, and RReMiT databases. Pain (2015) 0.75

Financial anatomy of neuroscience research. Ann Neurol (2008) 0.75

Clopidogrel and aspirin versus aspirin alone for the prevention of atherothrombotic events. N Engl J Med (2006) 18.25

Forecasting the future of cardiovascular disease in the United States: a policy statement from the American Heart Association. Circulation (2011) 14.00

Guidelines for the prevention of stroke in patients with stroke or transient ischemic attack: a guideline for healthcare professionals from the american heart association/american stroke association. Stroke (2010) 10.66

Clopidogrel with aspirin in acute minor stroke or transient ischemic attack. N Engl J Med (2013) 8.76

Guidelines for prevention of stroke in patients with ischemic stroke or transient ischemic attack: a statement for healthcare professionals from the American Heart Association/American Stroke Association Council on Stroke: co-sponsored by the Council on Cardiovascular Radiology and Intervention: the American Academy of Neurology affirms the value of this guideline. Stroke (2006) 8.30

Definition and evaluation of transient ischemic attack: a scientific statement for healthcare professionals from the American Heart Association/American Stroke Association Stroke Council; Council on Cardiovascular Surgery and Anesthesia; Council on Cardiovascular Radiology and Intervention; Council on Cardiovascular Nursing; and the Interdisciplinary Council on Peripheral Vascular Disease. The American Academy of Neurology affirms the value of this statement as an educational tool for neurologists. Stroke (2009) 6.62

2015 American Heart Association/American Stroke Association Focused Update of the 2013 Guidelines for the Early Management of Patients With Acute Ischemic Stroke Regarding Endovascular Treatment: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association. Stroke (2015) 5.64

Should the Babinski sign be part of the routine neurologic examination? Neurology (2005) 5.57

Funding of US biomedical research, 2003-2008. JAMA (2010) 5.33

Midlife cardiovascular risk factors and risk of dementia in late life. Neurology (2005) 5.12

Movement Disorder Society Task Force report on the Hoehn and Yahr staging scale: status and recommendations. Mov Disord (2004) 4.83

The beautiful and ethereal neurological exam: an appeal for research. Ann Neurol (2011) 4.10

Update to the AHA/ASA recommendations for the prevention of stroke in patients with stroke and transient ischemic attack. Stroke (2008) 4.06

Recommendations for the establishment of stroke systems of care: recommendations from the American Stroke Association's Task Force on the Development of Stroke Systems. Stroke (2005) 3.74

Association between stroke center hospitalization for acute ischemic stroke and mortality. JAMA (2011) 3.68

Risk of stroke in children: ethnic and gender disparities. Neurology (2003) 3.47

Stroke Prognostication using Age and NIH Stroke Scale: SPAN-100. Neurology (2012) 3.20

Global variation in the relative burden of stroke and ischemic heart disease. Circulation (2011) 3.02

Guidelines for prevention of stroke in patients with ischemic stroke or transient ischemic attack: a statement for healthcare professionals from the American Heart Association/American Stroke Association Council on Stroke: co-sponsored by the Council on Cardiovascular Radiology and Intervention: the American Academy of Neurology affirms the value of this guideline. Circulation (2006) 2.86

Proactive palliative care in the medical intensive care unit: effects on length of stay for selected high-risk patients. Crit Care Med (2007) 2.76

A review of the evidence for the use of telemedicine within stroke systems of care: a scientific statement from the American Heart Association/American Stroke Association. Stroke (2009) 2.74

Abnormalities of intrinsic functional connectivity in autism spectrum disorders. Neuroimage (2009) 2.74

Forecasting the future of stroke in the United States: a policy statement from the American Heart Association and American Stroke Association. Stroke (2013) 2.66

Patients with prior myocardial infarction, stroke, or symptomatic peripheral arterial disease in the CHARISMA trial. J Am Coll Cardiol (2007) 2.56

NIH disease funding levels and burden of disease. PLoS One (2011) 2.56

Hospital usage of early do-not-resuscitate orders and outcome after intracerebral hemorrhage. Stroke (2004) 2.42

Recommendations for the establishment of stroke systems of care: recommendations from the American Stroke Association's Task Force on the Development of Stroke Systems. Circulation (2005) 2.38

Risk of recurrent childhood arterial ischemic stroke in a population-based cohort: the importance of cerebrovascular imaging. Pediatrics (2007) 2.29

Head computed tomography findings predict short-term stroke risk after transient ischemic attack. Stroke (2003) 2.28

Racial/Ethnic differences in longitudinal risk of intracranial hemorrhage in brain arteriovenous malformation patients. Stroke (2007) 2.26

Alterations of resting state functional connectivity in the default network in adolescents with autism spectrum disorders. Brain Res (2009) 2.21

Reasons why few patients with acute stroke receive tissue plasminogen activator. Arch Neurol (2006) 2.17

Influence of physician specialty on outcomes after acute ischemic stroke. J Hosp Med (2008) 2.07

Incomplete inhibition of thromboxane biosynthesis by acetylsalicylic acid: determinants and effect on cardiovascular risk. Circulation (2008) 2.05

Getting youth in the game: can we accelerate training for clinician-scientists? Ann Neurol (2010) 2.04

Predicting clinical outcomes after thrombolysis using the iScore: results from the Virtual International Stroke Trials Archive. Stroke (2013) 2.01

Recent trauma and acute infection as risk factors for childhood arterial ischemic stroke. Ann Neurol (2012) 1.94

Recommendations for the endovascular treatment of intracranial aneurysms: a statement for healthcare professionals from the Committee on Cerebrovascular Imaging of the American Heart Association Council on Cardiovascular Radiology. Stroke (2002) 1.93

Moyamoya disease in Washington State and California. Neurology (2005) 1.88

Clinical- and imaging-based prediction of stroke risk after transient ischemic attack: the CIP model. Stroke (2008) 1.88

Thirty-year projections for deaths from ischemic stroke in the United States. Stroke (2003) 1.86

Intracranial atherosclerotic disease: an update. Ann Neurol (2009) 1.86

Metrics for measuring quality of care in comprehensive stroke centers: detailed follow-up to Brain Attack Coalition comprehensive stroke center recommendations: a statement for healthcare professionals from the American Heart Association/American Stroke Association. Stroke (2011) 1.85

Statin use during ischemic stroke hospitalization is strongly associated with improved poststroke survival. Stroke (2011) 1.84

Declining stroke rates in Californian children with sickle cell disease. Blood (2004) 1.83

Association between subarachnoid hemorrhage outcomes and number of cases treated at California hospitals. Stroke (2002) 1.80

Neural activation to emotional faces in adolescents with autism spectrum disorders. J Child Psychol Psychiatry (2010) 1.79

Impact of hospital-related factors on outcome after treatment of cerebral aneurysms. Stroke (2003) 1.78

Long-term hemorrhage risk in children versus adults with brain arteriovenous malformations. Stroke (2005) 1.78

Longitudinal risk of intracranial hemorrhage in patients with arteriovenous malformation of the brain within a defined population. Stroke (2004) 1.74

Predictors and outcomes of intraprocedural rupture in patients treated for ruptured intracranial aneurysms: the CARAT study. Stroke (2008) 1.72

A cost-utility analysis of mechanical thrombectomy as an adjunct to intravenous tissue-type plasminogen activator for acute large-vessel ischemic stroke. Stroke (2011) 1.72

Translational research for a new administration: what sort of change to believe in? Ann Neurol (2008) 1.71

Cost-effectiveness of outpatient cardiac monitoring to detect atrial fibrillation after ischemic stroke. Stroke (2010) 1.71

Cardiovascular risk management and its impact on hypertension control in primary care in low-resource settings: a cluster-randomized trial. Bull World Health Organ (2009) 1.70

Application of the ABCD2 score to identify cerebrovascular causes of dizziness in the emergency department. Stroke (2012) 1.65

Recruiting subjects for acute stroke trials: a meta-analysis. Stroke (2005) 1.65

Association between major perioperative hemorrhage and stroke or Q-wave myocardial infarction. Circulation (2012) 1.58

Significance of large vessel intracranial occlusion causing acute ischemic stroke and TIA. Stroke (2009) 1.56

Imaging data reveal a higher pediatric stroke incidence than prior US estimates. Stroke (2009) 1.56

Neurological disease on the global agenda. Ann Neurol (2008) 1.56

High critical care usage due to pediatric stroke: results of a population-based study. Neurology (2012) 1.56

Financing of U.S. biomedical research and new drug approvals across therapeutic areas. PLoS One (2009) 1.55

Comparison of 2 approaches for determining the natural history risk of brain arteriovenous malformation rupture. Am J Epidemiol (2010) 1.53

Health state preferences and decision-making after malignant middle cerebral artery infarctions. Neurology (2010) 1.52

Recurrent hemorrhagic stroke in children: a population-based cohort study. Stroke (2007) 1.51

The influence of body mass index on mortality and bleeding among patients with or at high-risk of atherothrombotic disease. Eur Heart J (2009) 1.49

The dangers of clinical conviction: an "M&M" of endovascular therapies for stroke. Ann Neurol (2013) 1.48

Why are eligible thrombolysis candidates left untreated? Am J Prev Med (2006) 1.45

Neural circuitry of emotional face processing in autism spectrum disorders. J Psychiatry Neurosci (2010) 1.45

Ten-year detection rate of brain arteriovenous malformations in a large, multiethnic, defined population. Stroke (2009) 1.44

4-aminopyridine: new life for an old drug. Ann Neurol (2010) 1.43

Tumor necrosis factor-alpha-238G>A promoter polymorphism is associated with increased risk of new hemorrhage in the natural course of patients with brain arteriovenous malformations. Stroke (2005) 1.40

Journeys in complex genetics: music and mental illness. Ann Neurol (2009) 1.39

Electronic medical records: does it take a village or a thousand points of light? Ann Neurol (2008) 1.39

That vexing problem of compensation. Ann Neurol (2008) 1.39

Safety and feasibility of a CT protocol for acute stroke: combined CT, CT angiography, and CT perfusion imaging in 53 consecutive patients. AJNR Am J Neuroradiol (2003) 1.37

An approach to evaluating the therapeutic misconception. IRB (2009) 1.35

Addition of brain infarction to the ABCD2 Score (ABCD2I): a collaborative analysis of unpublished data on 4574 patients. Stroke (2010) 1.35

Recent advances in management of transient ischaemic attacks and minor ischaemic strokes. Lancet Neurol (2006) 1.33

Breast vascular calcification and risk of coronary heart disease, stroke, and heart failure. J Womens Health (Larchmt) (2004) 1.32

Higher ABCD2 score predicts patients most likely to have true transient ischemic attack. Stroke (2008) 1.28

Evidence, preferences, recommendations--finding the right balance in patient care. N Engl J Med (2012) 1.26

What should be done to improve the productivity of neurological research? Ann Neurol (2006) 1.25

A status report on neuroscience research, without grade inflation. Ann Neurol (2006) 1.24

The iScore predicts effectiveness of thrombolytic therapy for acute ischemic stroke. Stroke (2012) 1.24

Effect of presenting hemorrhage on outcome after microsurgical resection of brain arteriovenous malformations. Neurosurgery (2005) 1.22

Profiles of lacunar and nonlacunar stroke. Ann Neurol (2011) 1.19

Basic and clinical research: what is the most appropriate weighting in a public investment portfolio? Ann Neurol (2006) 1.18

Palliative and end-of-life care in stroke: a statement for healthcare professionals from the American Heart Association/American Stroke Association. Stroke (2014) 1.17

Rationale and design of a randomized, double-blind trial comparing the effects of a 3-month clopidogrel-aspirin regimen versus aspirin alone for the treatment of high-risk patients with acute nondisabling cerebrovascular event. Am Heart J (2010) 1.16

How accurate is CT angiography in evaluating intracranial atherosclerotic disease? Stroke (2008) 1.16

External validation of the ICH score. Neurocrit Care (2004) 1.16

Cost-effectiveness of dabigatran compared with warfarin for stroke prevention in patients with atrial fibrillation and prior stroke or transient ischemic attack. Stroke (2012) 1.15