Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
1
|
Characterization of a naturally occurring breast cancer subset enriched in epithelial-to-mesenchymal transition and stem cell characteristics.
|
Cancer Res
|
2009
|
5.68
|
2
|
Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver.
|
Proc Natl Acad Sci U S A
|
2010
|
4.95
|
3
|
Ubiquitous activation of Ras and Jak/Stat pathways in human HCC.
|
Gastroenterology
|
2006
|
3.95
|
4
|
Met-regulated expression signature defines a subset of human hepatocellular carcinomas with poor prognosis and aggressive phenotype.
|
J Clin Invest
|
2006
|
3.95
|
5
|
Regulation of tumor angiogenesis by EZH2.
|
Cancer Cell
|
2010
|
3.10
|
6
|
A unique metastasis gene signature enables prediction of tumor relapse in early-stage hepatocellular carcinoma patients.
|
Cancer Res
|
2010
|
2.59
|
7
|
Mechanistic and prognostic significance of aberrant methylation in the molecular pathogenesis of human hepatocellular carcinoma.
|
J Clin Invest
|
2007
|
2.53
|
8
|
Sixty-five gene-based risk score classifier predicts overall survival in hepatocellular carcinoma.
|
Hepatology
|
2012
|
2.40
|
9
|
Intrinsic subtypes of gastric cancer, based on gene expression pattern, predict survival and respond differently to chemotherapy.
|
Gastroenterology
|
2011
|
2.36
|
10
|
Deletion of p120-catenin results in a tumor microenvironment with inflammation and cancer that establishes it as a tumor suppressor gene.
|
Cancer Cell
|
2011
|
2.10
|
11
|
LIN28B promotes colon cancer progression and metastasis.
|
Cancer Res
|
2011
|
2.05
|
12
|
Functional genomics of hepatocellular carcinoma.
|
Hepatology
|
2006
|
2.02
|
13
|
Downregulation of KLF6 is an early event in hepatocarcinogenesis, and stimulates proliferation while reducing differentiation.
|
J Hepatol
|
2006
|
1.98
|
14
|
Sulfatase 2 up-regulates glypican 3, promotes fibroblast growth factor signaling, and decreases survival in hepatocellular carcinoma.
|
Hepatology
|
2008
|
1.87
|
15
|
Gene expression signature-based prognostic risk score in gastric cancer.
|
Clin Cancer Res
|
2011
|
1.83
|
16
|
Dual inhibition of tumor energy pathway by 2-deoxyglucose and metformin is effective against a broad spectrum of preclinical cancer models.
|
Mol Cancer Ther
|
2011
|
1.81
|
17
|
Astrocytes upregulate survival genes in tumor cells and induce protection from chemotherapy.
|
Neoplasia
|
2011
|
1.78
|
18
|
Gastric cancer-molecular and clinical dimensions.
|
Nat Rev Clin Oncol
|
2013
|
1.72
|
19
|
Integrative analysis of proteomic signatures, mutations, and drug responsiveness in the NCI 60 cancer cell line set.
|
Mol Cancer Ther
|
2010
|
1.62
|
20
|
Periostin, a cell adhesion molecule, facilitates invasion in the tumor microenvironment and annotates a novel tumor-invasive signature in esophageal cancer.
|
Cancer Res
|
2010
|
1.58
|
21
|
Upregulated stromal EGFR and vascular remodeling in mouse xenograft models of angiogenesis inhibitor-resistant human lung adenocarcinoma.
|
J Clin Invest
|
2011
|
1.52
|
22
|
Identification of potential driver genes in human liver carcinoma by genomewide screening.
|
Cancer Res
|
2009
|
1.45
|
23
|
Integrative analysis of cyclin protein levels identifies cyclin b1 as a classifier and predictor of outcomes in breast cancer.
|
Clin Cancer Res
|
2009
|
1.43
|
24
|
Targeted delivery of small interfering RNA using reconstituted high-density lipoprotein nanoparticles.
|
Neoplasia
|
2011
|
1.42
|
25
|
Comprehensive genomic meta-analysis identifies intra-tumoural stroma as a predictor of survival in patients with gastric cancer.
|
Gut
|
2012
|
1.42
|
26
|
Cross-species hybridization of microarrays for studying tumor transcriptome of brain metastasis.
|
Proc Natl Acad Sci U S A
|
2011
|
1.41
|
27
|
Gene expression-based recurrence prediction of hepatitis B virus-related human hepatocellular carcinoma.
|
Clin Cancer Res
|
2008
|
1.41
|
28
|
Chemotherapy and radiotherapy resistance: complexity, reality, and promise.
|
J Clin Oncol
|
2008
|
1.39
|
29
|
RB loss abrogates cell cycle control and genome integrity to promote liver tumorigenesis.
|
Gastroenterology
|
2007
|
1.36
|
30
|
Oncogene-specific gene expression signatures at preneoplastic stage in mice define distinct mechanisms of hepatocarcinogenesis.
|
Hepatology
|
2006
|
1.34
|
31
|
Prognostic biomarkers for esophageal adenocarcinoma identified by analysis of tumor transcriptome.
|
PLoS One
|
2010
|
1.33
|
32
|
Prognostic gene expression signature associated with two molecularly distinct subtypes of colorectal cancer.
|
Gut
|
2011
|
1.32
|
33
|
Development and validation of a prognostic gene-expression signature for lung adenocarcinoma.
|
PLoS One
|
2012
|
1.28
|
34
|
The Prrx1 homeodomain transcription factor plays a central role in pancreatic regeneration and carcinogenesis.
|
Genes Dev
|
2013
|
1.28
|
35
|
Hepatic precursors derived from murine embryonic stem cells contribute to regeneration of injured liver.
|
Hepatology
|
2006
|
1.27
|
36
|
LIN28B promotes growth and tumorigenesis of the intestinal epithelium via Let-7.
|
Genes Dev
|
2013
|
1.23
|
37
|
FOXM1 mediates Dox resistance in breast cancer by enhancing DNA repair.
|
Carcinogenesis
|
2012
|
1.22
|
38
|
Gene expression signature analysis identifies vorinostat as a candidate therapy for gastric cancer.
|
PLoS One
|
2011
|
1.17
|
39
|
Global gene expression profiles of human head and neck squamous carcinoma cell lines.
|
Int J Cancer
|
2004
|
1.13
|
40
|
Molecular prognostication of liver cancer: end of the beginning.
|
J Hepatol
|
2006
|
1.12
|
41
|
Human nuclease/helicase DNA2 alleviates replication stress by promoting DNA end resection.
|
Cancer Res
|
2012
|
1.10
|
42
|
ARAP1 regulates endocytosis of EGFR.
|
Traffic
|
2008
|
1.10
|
43
|
Silencing of p130cas in ovarian carcinoma: a novel mechanism for tumor cell death.
|
J Natl Cancer Inst
|
2011
|
1.08
|
44
|
HOXA9 promotes ovarian cancer growth by stimulating cancer-associated fibroblasts.
|
J Clin Invest
|
2012
|
1.07
|
45
|
Wnt pathway contributes to the protection by bone marrow stromal cells of acute lymphoblastic leukemia cells and is a potential therapeutic target.
|
Cancer Lett
|
2013
|
1.04
|
46
|
Rab25 increases cellular ATP and glycogen stores protecting cancer cells from bioenergetic stress.
|
EMBO Mol Med
|
2012
|
1.03
|
47
|
ANGPTL4 induction by prostaglandin E2 under hypoxic conditions promotes colorectal cancer progression.
|
Cancer Res
|
2011
|
1.02
|
48
|
Sulfatase 1 and sulfatase 2 in hepatocellular carcinoma: associated signaling pathways, tumor phenotypes, and survival.
|
Genes Chromosomes Cancer
|
2011
|
1.02
|
49
|
GLIPR1 suppresses prostate cancer development through targeted oncoprotein destruction.
|
Cancer Res
|
2011
|
0.98
|
50
|
Reconstruction of nuclear receptor network reveals that NR2E3 is a novel upstream regulator of ESR1 in breast cancer.
|
EMBO Mol Med
|
2011
|
0.97
|
51
|
Tat-activating regulatory DNA-binding protein regulates glycolysis in hepatocellular carcinoma by regulating the platelet isoform of phosphofructokinase through microRNA 520.
|
Hepatology
|
2013
|
0.96
|
52
|
Induction of the transcriptional repressor ZBTB4 in prostate cancer cells by drug-induced targeting of microRNA-17-92/106b-25 clusters.
|
Mol Cancer Ther
|
2012
|
0.96
|
53
|
Overexpression of miR-196b and HOXA10 characterize a poor-prognosis gastric cancer subtype.
|
World J Gastroenterol
|
2013
|
0.96
|
54
|
Spontaneous differentiation of mouse embryonic stem cells in vitro: characterization by global gene expression profiles.
|
Biochem Biophys Res Commun
|
2005
|
0.94
|
55
|
Hint2, a mitochondrial apoptotic sensitizer down-regulated in hepatocellular carcinoma.
|
Gastroenterology
|
2006
|
0.94
|
56
|
Epidermal growth factor receptor and K-Ras mutations and resistance of lung cancer to insulin-like growth factor 1 receptor tyrosine kinase inhibitors.
|
Cancer
|
2012
|
0.92
|
57
|
nc886, a non-coding RNA of anti-proliferative role, is suppressed by CpG DNA methylation in human gastric cancer.
|
Oncotarget
|
2014
|
0.92
|
58
|
Optical imaging of periostin enables early endoscopic detection and characterization of esophageal cancer in mice.
|
Gastroenterology
|
2012
|
0.91
|
59
|
Systems-level analysis of gene expression data revealed NR0B2/SHP as potential tumor suppressor in human liver cancer.
|
Mol Cells
|
2010
|
0.91
|
60
|
Gene expression profiling demonstrates that TGF-beta1 signals exclusively through receptor complexes involving Alk5 and identifies targets of TGF-beta signaling.
|
Physiol Genomics
|
2005
|
0.90
|
61
|
Comparison of prognostic genomic predictors in colorectal cancer.
|
PLoS One
|
2013
|
0.90
|
62
|
Rapamycin response in tumorigenic and non-tumorigenic hepatic cell lines.
|
PLoS One
|
2009
|
0.90
|
63
|
Genes associated with recurrence of hepatocellular carcinoma: integrated analysis by gene expression and methylation profiling.
|
J Korean Med Sci
|
2011
|
0.89
|
64
|
Molecular profiling of hepatocellular carcinomas developing spontaneously in acyl-CoA oxidase deficient mice: comparison with liver tumors induced in wild-type mice by a peroxisome proliferator and a genotoxic carcinogen.
|
Carcinogenesis
|
2003
|
0.89
|
65
|
ATP11B mediates platinum resistance in ovarian cancer.
|
J Clin Invest
|
2013
|
0.88
|
66
|
Protein L-isoaspartyl methyltransferase regulates p53 activity.
|
Nat Commun
|
2012
|
0.88
|
67
|
Selection of brain metastasis-initiating breast cancer cells determined by growth on hard agar.
|
Am J Pathol
|
2011
|
0.88
|
68
|
First generation prognostic gene signatures for breast cancer predict both survival and chemotherapy sensitivity and identify overlapping patient populations.
|
Breast Cancer Res Treat
|
2011
|
0.86
|
69
|
Glioma pathogenesis-related protein 1 induces prostate cancer cell death through Hsc70-mediated suppression of AURKA and TPX2.
|
Mol Oncol
|
2012
|
0.86
|
70
|
Inhibition of the proliferation and invasion of hepatocellular carcinoma cells by lipocalin 2 through blockade of JNK and PI3K/Akt signaling.
|
Int J Oncol
|
2010
|
0.86
|
71
|
Gene expression profiling reveals different pathways related to Abl and other genes that cooperate with c-Myc in a model of plasma cell neoplasia.
|
BMC Genomics
|
2007
|
0.86
|
72
|
Regulation of gene expression in hepatic cells by the mammalian Target of Rapamycin (mTOR).
|
PLoS One
|
2010
|
0.85
|
73
|
Oligonucleotide microarray analysis of aminoallyl-labeled cDNA targets from linear RNA amplification.
|
Biotechniques
|
2004
|
0.85
|
74
|
A Gprc5a tumor suppressor loss of expression signature is conserved, prevalent, and associated with survival in human lung adenocarcinomas.
|
Neoplasia
|
2010
|
0.84
|
75
|
c-Jun N-terminal kinase 2 (JNK2) enhances cell migration through epidermal growth factor substrate 8 (EPS8).
|
J Biol Chem
|
2011
|
0.84
|
76
|
Kinome expression profiling identifies IKBKE as a predictor of overall survival in clear cell renal cell carcinoma patients.
|
Carcinogenesis
|
2012
|
0.83
|
77
|
Heterologous tissue culture expression signature predicts human breast cancer prognosis.
|
PLoS One
|
2007
|
0.81
|
78
|
CellMinerHCC: a microarray-based expression database for hepatocellular carcinoma cell lines.
|
Liver Int
|
2013
|
0.80
|
79
|
HIG2 promotes colorectal cancer progression via hypoxia-dependent and independent pathways.
|
Cancer Lett
|
2013
|
0.79
|
80
|
3,3'-Diindolylmethane suppresses growth of human esophageal squamous cancer cells by G1 cell cycle arrest.
|
Oncol Rep
|
2012
|
0.79
|
81
|
DNMT3A Loss Drives Enhancer Hypomethylation in FLT3-ITD-Associated Leukemias.
|
Cancer Cell
|
2016
|
0.78
|
82
|
An expression signature of phenotypic resistance to hepatocellular carcinoma identified by cross-species gene expression analysis.
|
Cell Oncol (Dordr)
|
2012
|
0.78
|
83
|
Acquired genetic and functional alterations associated with transforming growth factor beta type I resistance in Hep3B human hepatocellular carcinoma cell line.
|
J Cell Mol Med
|
2009
|
0.78
|
84
|
Deciphering the role of paclitaxel in the SKGT4 human esophageal adenocarcinoma cell line.
|
Int J Oncol
|
2011
|
0.76
|
85
|
Reassessing hepatocellular carcinoma staging in a changing patient population.
|
Oncology
|
2014
|
0.76
|
86
|
Reply: To PMID 22105560.
|
Hepatology
|
2013
|
0.75
|
87
|
In silico analysis of genomic data for construction of nuclear receptor network.
|
Methods Mol Biol
|
2014
|
0.75
|