PubRank

John Guy

Author PubWeight™ 27.22‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Rescue of a deficiency in ATP synthesis by transfer of MTATP6, a mitochondrial DNA-encoded gene, to the nucleus. Nat Genet 2002 2.20
2 Gene delivery to mitochondria by targeting modified adenoassociated virus suppresses Leber's hereditary optic neuropathy in a mouse model. Proc Natl Acad Sci U S A 2012 1.94
3 SOD2 gene transfer protects against optic neuropathy induced by deficiency of complex I. Ann Neurol 2004 1.70
4 Suppression of mitochondrial oxidative stress provides long-term neuroprotection in experimental optic neuritis. Invest Ophthalmol Vis Sci 2007 1.40
5 The mutant human ND4 subunit of complex I induces optic neuropathy in the mouse. Invest Ophthalmol Vis Sci 2007 1.26
6 Mitochondrial protein nitration primes neurodegeneration in experimental autoimmune encephalomyelitis. J Biol Chem 2006 1.25
7 Cone-specific expression using a human red opsin promoter in recombinant AAV. Vision Res 2007 1.14
8 Optic neuropathy induced by reductions in mitochondrial superoxide dismutase. Invest Ophthalmol Vis Sci 2003 1.13
9 Long-term suppression of neurodegeneration in chronic experimental optic neuritis: antioxidant gene therapy. Invest Ophthalmol Vis Sci 2007 1.05
10 Leber hereditary optic neuropathy gene therapy clinical trial recruitment: year 1. Arch Ophthalmol 2010 1.02
11 Dual gene therapy with extracellular superoxide dismutase and catalase attenuates experimental optic neuritis. Mol Vis 2007 0.98
12 Leber's Hereditary Optic Neuropathy-Gene Therapy: From Benchtop to Bedside. J Ophthalmol 2010 0.96
13 Suppression of complex I gene expression induces optic neuropathy. Ann Neurol 2003 0.96
14 Use of mitochondrial antioxidant defenses for rescue of cells with a Leber hereditary optic neuropathy-causing mutation. Arch Ophthalmol 2007 0.95
15 Induction of rapid and highly efficient expression of the human ND4 complex I subunit in the mouse visual system by self-complementary adeno-associated virus. Arch Ophthalmol 2010 0.93
16 Phosphorylated neurofilament heavy chain correlations to visual function, optical coherence tomography, and treatment. Mult Scler Int 2011 0.90
17 Mutant NADH dehydrogenase subunit 4 gene delivery to mitochondria by targeting sequence-modified adeno-associated virus induces visual loss and optic atrophy in mice. Mol Vis 2012 0.88
18 Noninvasive assessments of optic nerve neurodegeneration in transgenic mice with isolated optic neuritis. Invest Ophthalmol Vis Sci 2013 0.86
19 Efficient expression of self-complementary AAV in ganglion cells of the ex vivo primate retina. Mol Vis 2009 0.85
20 Idiopathic intracranial hypertension in a transgender man. J Neuroophthalmol 2007 0.84
21 NADH-dehydrogenase type-2 suppresses irreversible visual loss and neurodegeneration in the EAE animal model of MS. Mol Ther 2013 0.82
22 Next-generation sequencing of mitochondrial targeted AAV transfer of human ND4 in mice. Mol Vis 2013 0.81
23 Improving Participation in Colorectal Cancer Screening: a Randomised Controlled Trial of Sequential Offers of Faecal then Blood Based Non-Invasive Tests. Asian Pac J Cancer Prev 2015 0.80
24 Visual observations of an American patient with Leber hereditary optic neuropathy after purported injections of stem cells in China. Arch Ophthalmol 2012 0.79
25 Sixth nerve palsy post intravitreal bevacizumab for AMD: a new possibly causal relationship and complication? Binocul Vis Strabismus Q 2007 0.78
26 Macular Retinal Sublayer Thicknesses in G11778A Leber Hereditary Optic Neuropathy. Ophthalmic Surg Lasers Imaging Retina 2016 0.75