Published in J Neurosci on January 03, 2007
Molecular and cellular basis of small--and intermediate-conductance, calcium-activated potassium channel function in the brain. Cell Mol Life Sci (2008) 1.67
Therapeutic potential of KCa3.1 blockers: recent advances and promising trends. Expert Rev Clin Pharmacol (2010) 1.56
K+ channel modulators for the treatment of neurological disorders and autoimmune diseases. Chem Rev (2008) 1.52
Amyloid-beta protein oligomer at low nanomolar concentrations activates microglia and induces microglial neurotoxicity. J Biol Chem (2010) 1.37
Intermediate conductance calcium-activated potassium channels modulate summation of parallel fiber input in cerebellar Purkinje cells. Proc Natl Acad Sci U S A (2012) 1.17
KCa3.1 channels are involved in the infiltrative behavior of glioblastoma in vivo. Cell Death Dis (2013) 1.10
The KCa3.1 blocker TRAM-34 reduces infarction and neurological deficit in a rat model of ischemia/reperfusion stroke. J Cereb Blood Flow Metab (2011) 1.08
The microglial activation state regulates migration and roles of matrix-dissolving enzymes for invasion. J Neuroinflammation (2013) 1.07
Endothelial small-conductance and intermediate-conductance KCa channels: an update on their pharmacology and usefulness as cardiovascular targets. J Cardiovasc Pharmacol (2013) 1.05
Microglia induce neurotoxicity via intraneuronal Zn(2+) release and a K(+) current surge. Glia (2008) 1.01
The Lymphocyte Potassium Channels Kv1.3 and KCa3.1 as Targets for Immunosuppression. Drug Dev Res (2011) 0.98
The Ca2+ activated SK3 channel is expressed in microglia in the rat striatum and contributes to microglia-mediated neurotoxicity in vitro. J Neuroinflammation (2010) 0.98
T-type channels buddy up. Pflugers Arch (2014) 0.95
Selective activation of KCa3.1 and CRAC channels by P2Y2 receptors promotes Ca(2+) signaling, store refilling and migration of rat microglial cells. PLoS One (2013) 0.94
Predominant functional expression of Kv1.3 by activated microglia of the hippocampus after Status epilepticus. PLoS One (2009) 0.94
Genetic KCa3.1-deficiency produces locomotor hyperactivity and alterations in cerebral monoamine levels. PLoS One (2012) 0.94
Regulation of podosome formation, microglial migration and invasion by Ca(2+)-signaling molecules expressed in podosomes. J Neuroinflammation (2012) 0.94
Calcium regulation of neural rhythms, memory and Alzheimer's disease. J Physiol (2013) 0.91
Microglial KCa3.1 Channels as a Potential Therapeutic Target for Alzheimer's Disease. Int J Alzheimers Dis (2012) 0.89
Podosomes in migrating microglia: components and matrix degradation. J Neuroinflammation (2012) 0.88
Expression and Role of the Intermediate-Conductance Calcium-Activated Potassium Channel KCa3.1 in Glioblastoma. J Signal Transduct (2012) 0.87
Protective Roles for Potassium SK/K(Ca)2 Channels in Microglia and Neurons. Front Pharmacol (2012) 0.86
Trafficking of intermediate (KCa3.1) and small (KCa2.x) conductance, Ca(2+)-activated K(+) channels: a novel target for medicinal chemistry efforts? ChemMedChem (2012) 0.86
Functional significance of the intermediate conductance Ca2+-activated K+ channel for the short-term survival of injured erythrocytes. Pflugers Arch (2010) 0.86
IL-4 type 1 receptor signaling up-regulates KCNN4 expression, and increases the KCa3.1 current and its contribution to migration of alternative-activated microglia. Front Cell Neurosci (2014) 0.84
Lipopolysaccharide-induced down-regulation of Ca2+ release-activated Ca2+ currents (I CRAC) but not Ca2+-activated TRPM4-like currents (I CAN) in cultured mouse microglial cells. J Physiol (2007) 0.84
Activation of KCNN3/SK3/K(Ca)2.3 channels attenuates enhanced calcium influx and inflammatory cytokine production in activated microglia. Glia (2012) 0.83
Control of hypothalamic-pituitary-adrenal stress axis activity by the intermediate conductance calcium-activated potassium channel, SK4. J Physiol (2011) 0.83
Functional KCa3.1 channels regulate steroid insensitivity in bronchial smooth muscle cells. J Immunol (2013) 0.82
K(Ca)2 and k(ca)3 channels in learning and memory processes, and neurodegeneration. Front Pharmacol (2012) 0.82
Microglial disruption in young mice with early chronic lead exposure. Toxicol Lett (2013) 0.82
Microglial ion channels as potential targets for neuroprotection in Parkinson's disease. Neural Plast (2013) 0.81
Expression and contributions of TRPM7 and KCa2.3/SK3 channels to the increased migration and invasion of microglia in anti-inflammatory activation states. PLoS One (2014) 0.81
Swelling activated Cl- channels in microglia: Biophysics, pharmacology and role in glutamate release. Channels (Austin) (2011) 0.81
The inhibitor of Ca(2+)-dependent K+ channels TRAM-34 blocks growth of hepatocellular carcinoma cells via downregulation of estrogen receptor alpha mRNA and nuclear factor-kappaB. Invest New Drugs (2012) 0.80
Neuronal expression of the intermediate conductance calcium-activated potassium channel KCa3.1 in the mammalian central nervous system. Pflugers Arch (2014) 0.80
KCa3.1/IK1 Channel Regulation by cGMP-Dependent Protein Kinase (PKG) via Reactive Oxygen Species and CaMKII in Microglia: An Immune Modulating Feedback System? Front Immunol (2015) 0.80
A novel pan-negative-gating modulator of KCa2/3 channels, fluoro-di-benzoate, RA-2, inhibits endothelium-derived hyperpolarization-type relaxation in coronary artery and produces bradycardia in vivo. Mol Pharmacol (2014) 0.80
Signal processing by T-type calcium channel interactions in the cerebellum. Front Cell Neurosci (2013) 0.79
Potassium channel Kv1.3 is highly expressed by microglia in human Alzheimer's disease. J Alzheimers Dis (2015) 0.79
Expression and contributions of the Kir2.1 inward-rectifier K(+) channel to proliferation, migration and chemotaxis of microglia in unstimulated and anti-inflammatory states. Front Cell Neurosci (2015) 0.79
Blood-brain barrier KCa3.1 channels: evidence for a role in brain Na uptake and edema in ischemic stroke. Stroke (2014) 0.79
TRAM-34, a putatively selective blocker of intermediate-conductance, calcium-activated potassium channels, inhibits cytochrome P450 activity. PLoS One (2013) 0.78
Brilliant blue G attenuates lipopolysaccharide-mediated microglial activation and inflammation. Neural Regen Res (2013) 0.78
The potassium channel KCa3.1 constitutes a pharmacological target for neuroinflammation associated with ischemia/reperfusion stroke. J Cereb Blood Flow Metab (2015) 0.78
Complex molecular and functional outcomes of single versus sequential cytokine stimulation of rat microglia. J Neuroinflammation (2016) 0.77
Parthenolide Relieves Pain and Promotes M2 Microglia/Macrophage Polarization in Rat Model of Neuropathy. Neural Plast (2015) 0.77
KCa3.1 inhibition switches the phenotype of glioma-infiltrating microglia/macrophages. Cell Death Dis (2016) 0.77
Effects of ibandronate sodium, a nitrogen-containing bisphosphonate, on intermediate-conductance calcium-activated potassium channels in osteoclast precursor cells (RAW 264.7). J Membr Biol (2014) 0.76
Sympathoexcitation in ANG II-salt hypertension involves reduced SK channel function in the hypothalamic paraventricular nucleus. Am J Physiol Heart Circ Physiol (2015) 0.76
KCa3.1 channel inhibition sensitizes malignant gliomas to temozolomide treatment. Oncotarget (2016) 0.76
Differential Kv1.3, KCa3.1, and Kir2.1 expression in "classically" and "alternatively" activated microglia. Glia (2016) 0.76
Senicapoc: Repurposing a Drug to Target Microglia KCa3.1 in Stroke. Neurochem Res (2017) 0.76
Signaling pathways regulating neuron-glia interaction and their implications in Alzheimer's disease. J Neurochem (2015) 0.75
JMV5656, A Novel Derivative of TLQP-21, Triggers the Activation of a Calcium-Dependent Potassium Outward Current in Microglial Cells. Front Cell Neurosci (2017) 0.75
Macrophage polarization: a key event in the secondary phase of acute spinal cord injury. J Cell Mol Med (2016) 0.75
The Potassium Channel KCa3.1 Represents a Valid Pharmacological Target for Astrogliosis-Induced Neuronal Impairment in a Mouse Model of Alzheimer's Disease. Front Pharmacol (2017) 0.75
Split-spectrum amplitude-decorrelation angiography with optical coherence tomography. Opt Express (2012) 5.60
Tea polyphenol (-)-epigallocatechin-3-gallate inhibits DNA methyltransferase and reactivates methylation-silenced genes in cancer cell lines. Cancer Res (2003) 3.72
Mechanisms of microglia-mediated neurotoxicity in a new model of the stroke penumbra. J Neurosci (2008) 2.48
Cell surface targeting and clustering interactions between heterologously expressed PSD-95 and the Shal voltage-gated potassium channel, Kv4.2. J Biol Chem (2002) 1.43
Functional up-regulation of HERG K+ channels in neoplastic hematopoietic cells. J Biol Chem (2002) 1.34
N-type Ca2+ channels carry the largest current: implications for nanodomains and transmitter release. Nat Neurosci (2010) 1.30
Minocycline protects the blood-brain barrier and reduces edema following intracerebral hemorrhage in the rat. Exp Neurol (2007) 1.28
Differential recruitment of Kv1.4 and Kv4.2 to lipid rafts by PSD-95. J Biol Chem (2003) 1.26
Evolution of the inflammatory response in the brain following intracerebral hemorrhage and effects of delayed minocycline treatment. Brain Res (2007) 1.26
Microglia Kv1.3 channels contribute to their ability to kill neurons. J Neurosci (2005) 1.24
Polymorphisms in the MMP1 and MMP3 promoter and non-small cell lung carcinoma in North China. Carcinogenesis (2004) 1.18
Compensatory anion currents in Kv1.3 channel-deficient thymocytes. J Biol Chem (2003) 1.17
Regulation of a TRPM7-like current in rat brain microglia. J Biol Chem (2003) 1.16
The RNA-binding protein HuR promotes glioma growth and treatment resistance. Mol Cancer Res (2011) 1.16
Neutrophil depletion reduces blood-brain barrier breakdown, axon injury, and inflammation after intracerebral hemorrhage. J Neuropathol Exp Neurol (2011) 1.16
Neuron death and inflammation in a rat model of intracerebral hemorrhage: effects of delayed minocycline treatment. Brain Res (2006) 1.13
Semantic Web for Health Care and Life Sciences: a review of the state of the art. Brief Bioinform (2009) 1.13
The functional polymorphism in the matrix metalloproteinase-7 promoter increases susceptibility to esophageal squamous cell carcinoma, gastric cardiac adenocarcinoma and non-small cell lung carcinoma. Carcinogenesis (2005) 1.12
Glial responses, neuron death and lesion resolution after intracerebral hemorrhage in young vs. aged rats. Eur J Neurosci (2008) 1.11
Regulation of an ERG K+ current by Src tyrosine kinase. J Biol Chem (2002) 1.09
Involvement of caspase-6 and caspase-8 in neuronal apoptosis and the regenerative failure of injured retinal ganglion cells. J Neurosci (2011) 1.09
The microglial activation state regulates migration and roles of matrix-dissolving enzymes for invasion. J Neuroinflammation (2013) 1.07
The Ca2+ release-activated Ca2+ current (I(CRAC)) mediates store-operated Ca2+ entry in rat microglia. Channels (Austin) (2009) 1.04
Integration of K+ and Cl- currents regulate steady-state and dynamic membrane potentials in cultured rat microglia. J Physiol (2005) 1.03
The functional SNP in the matrix metalloproteinase-3 promoter modifies susceptibility and lymphatic metastasis in esophageal squamous cell carcinoma but not in gastric cardiac adenocarcinoma. Carcinogenesis (2004) 1.01
White matter injury in young and aged rats after intracerebral hemorrhage. Exp Neurol (2008) 1.00
Optimal wavelength for ultrahigh-resolution optical coherence tomography. Opt Express (2003) 0.99
Evolution of inflammation and white matter injury in a model of transient focal ischemia. J Neuropathol Exp Neurol (2010) 0.98
Doppler optical coherence tomography of retinal circulation. J Vis Exp (2012) 0.95
Inhibition of the Ca²⁺-dependent K⁺ channel, KCNN4/KCa3.1, improves tissue protection and locomotor recovery after spinal cord injury. J Neurosci (2011) 0.95
Selective activation of KCa3.1 and CRAC channels by P2Y2 receptors promotes Ca(2+) signaling, store refilling and migration of rat microglial cells. PLoS One (2013) 0.94
Regulation of podosome formation, microglial migration and invasion by Ca(2+)-signaling molecules expressed in podosomes. J Neuroinflammation (2012) 0.94
Second-harmonic optical coherence tomography. Opt Lett (2004) 0.93
Promoter hypermethylation and inactivation of O(6)-methylguanine-DNA methyltransferase in esophageal squamous cell carcinomas and its reactivation in cell lines. Int J Oncol (2005) 0.92
Quantitative iTRAQ analysis of retinal ganglion cell degeneration after optic nerve crush. J Proteome Res (2011) 0.90
Reversed Na+/Ca2+ exchange contributes to Ca2+ influx and respiratory burst in microglia. Channels (Austin) (2007) 0.89
Small-conductance Cl- channels contribute to volume regulation and phagocytosis in microglia. Eur J Neurosci (2007) 0.89
Age-related comparisons of evolution of the inflammatory response after intracerebral hemorrhage in rats. Transl Stroke Res (2012) 0.89
Quantitative retinal protein analysis after optic nerve transection reveals a neuroprotective role for hepatoma-derived growth factor on injured retinal ganglion cells. Invest Ophthalmol Vis Sci (2012) 0.89
Flicker-induced changes in retinal blood flow assessed by Doppler optical coherence tomography. Biomed Opt Express (2011) 0.89
The effect of community-based health management on the health of the elderly: a randomized controlled trial from China. BMC Health Serv Res (2012) 0.89
Velocity profiles and shear strain rate variability in the USP Dissolution Testing Apparatus 2 at different impeller agitation speeds. Int J Pharm (2010) 0.89
The sonic hedgehog signaling pathway maintains the cancer stem cell self-renewal of anaplastic thyroid cancer by inducing snail expression. J Clin Endocrinol Metab (2014) 0.88
Podosomes in migrating microglia: components and matrix degradation. J Neuroinflammation (2012) 0.88
SC1/hevin and reactive gliosis after transient ischemic stroke in young and aged rats. J Neuropathol Exp Neurol (2011) 0.87
Dominance of E. coli phagocytosis over LPS in the inflammatory response of microglia. J Neuroimmunol (2010) 0.86
Conversion from cyclosporine to sirolimus in chronic renal allograft dysfunction: a 4-year prospective study. Exp Clin Transplant (2011) 0.86
Lazy S-curve epicanthoplasty in Asian blepharoplasty. Aesthetic Plast Surg (2011) 0.85
Association between the functional polymorphism in the matrix metalloproteinase-7 promoter and susceptibility to adult astrocytoma. Brain Res (2006) 0.85
The transmitter release-site CaV2.2 channel cluster is linked to an endocytosis coat protein complex. Eur J Neurosci (2007) 0.85
Optic nerve transection: a model of adult neuron apoptosis in the central nervous system. J Vis Exp (2011) 0.84
Using three-dimensional computational modeling to compare the geometrical fitness of two kinds of proximal femoral intramedullary nail for Chinese femur. ScientificWorldJournal (2013) 0.84
Ultrahigh-resolution optical coherence tomography with a fiber laser source at 1 microm. Opt Lett (2005) 0.83
Regulation of human Clara cell 10 kD protein expression by chicken ovalbumin upstream promoter transcription factors (COUP-TFs). Am J Respir Cell Mol Biol (2002) 0.83
Slope of changes in renal function in the first year post-transplantation and one-yr estimated glomerular filtration rate together predict long-term renal allograft survival. Clin Transplant (2010) 0.83
Health status and associated factors among the community-dwelling elderly in China. Arch Gerontol Geriatr (2012) 0.83
In vitro measurement of rabbit corneal epithelial thickness using ultrahigh resolution optical coherence tomography. Vet Ophthalmol (2005) 0.82
Modulation of the ERG K+ current by the tyrosine phosphatase, SHP-1. J Biol Chem (2002) 0.82
What can we learn about stroke from retinal ischemia models? Acta Pharmacol Sin (2012) 0.81
Semantic mashup of biomedical data. J Biomed Inform (2008) 0.81
Polymorphisms in the matrix metalloproteinase-1, 3, and 9 promoters and susceptibility to adult astrocytoma in northern China. J Neurooncol (2007) 0.81
Identification of appropriate reference genes for human mesenchymal stem cell analysis by quantitative real-time PCR. Biotechnol Lett (2014) 0.81
The function of constructed wetland in reducing the risk of heavy metals on human health. Environ Monit Assess (2011) 0.80
A tumor pH-responsive complex: carboxyl-modified hyperbranched polyether and cis-dichlorodiammineplatinum(II). Colloids Surf B Biointerfaces (2011) 0.80
Silencing SATB1 inhibits proliferation of human osteosarcoma U2OS cells. Mol Cell Biochem (2013) 0.80
Accurate ab initio and "hybrid" potential energy surfaces, intramolecular vibrational energies, and classical ir spectrum of the water dimer. J Chem Phys (2009) 0.80
C4d deposition in allograft renal biopsies is an independent risk factor for graft failure. Nephrology (Carlton) (2009) 0.79
Targeting K(V) channels rescues retinal ganglion cells in vivo directly and by reducing inflammation. Channels (Austin) (2010) 0.79
Experimental and theoretical investigations of energy transfer and hydrogen-bond breaking in small water and HCl clusters. Acc Chem Res (2014) 0.78
Impact of acute rejection episodes on long-term renal allograft survival. Chin Med J (Engl) (2003) 0.78
Description of Lentzea flaviverrucosa sp. nov. and transfer of the type strain of Saccharothrix aerocolonigenes subsp. staurosporea to Lentzea albida. Int J Syst Evol Microbiol (2002) 0.78
Activation loop phosphorylation-independent kinase activity of human protein kinase C zeta. Proteins (2007) 0.78
Association of polymorphisms of leptin gene with body weight and body sizes indexes in Chinese indigenous cattle. J Genet Genomics (2007) 0.77
Gene therapy for traumatic central nervous system injury and stroke using an engineered zinc finger protein that upregulates VEGF-A. J Neurotrauma (2011) 0.77
Methods for experimental manipulations after optic nerve transection in the Mammalian CNS. J Vis Exp (2011) 0.77
Clinical significance of the stem cell gene Oct-4 in cervical cancer. Tumour Biol (2014) 0.76
SC1/hevin identifies early white matter injury after ischemia and intracerebral hemorrhage in young and aged rats. J Neuropathol Exp Neurol (2012) 0.76
Local-monomer calculations of the intramolecular IR spectra of the cage and prism isomers of HOD(D2O)5 and HOD and D2O ice Ih. J Phys Chem B (2014) 0.75
Vibrational analysis of an ice Ih model from 0 to 4000 cm(-1) using the ab initio WHBB potential energy surface. J Phys Chem B (2013) 0.75
Experimental and theoretical investigations of the dissociation energy (D0) and dynamics of the water trimer, (H2O)3. J Phys Chem A (2013) 0.75
Identification of the binding site of an allosteric ligand using STD-NMR, docking, and CORCEMA-ST calculations. ChemMedChem (2013) 0.75
Reduced-dose cyclosporine with mycophenolate mofetil and prednisone significantly improves the long-term glomerular filtration rate and graft survival. Intern Med (2012) 0.75
Dipole surface and infrared intensities for the cis- and trans-HOCO and DOCO radicals. J Phys Chem A (2012) 0.75
The theoretical prediction of infrared spectra of trans- and cis-hydroxycarbene calculated using full dimensional ab initio potential energy and dipole moment surfaces. J Chem Phys (2008) 0.75
Nasal measurements in Asians and high-density porous polyethylene implants in rhinoplasty. Arch Facial Plast Surg (2012) 0.75
Full-dimensional (15-dimensional) ab initio analytical potential energy surface for the H7+ cluster. J Chem Phys (2012) 0.75
Calculations and measurements of the deuterium tunneling frequency in the propiolic acid-formic acid dimer and description of a newly constructed Fourier transform microwave spectrometer. J Chem Phys (2013) 0.75
Quasi-classical trajectory study of the HO + CO → H + CO2 reaction on a new ab initio based potential energy surface. J Phys Chem A (2012) 0.75
Rapid measurement of transversal flow velocity vector with high spatial resolution using speckle decorrelation optical coherence tomography. Opt Lett (2017) 0.75
Reduced-dimensional quantum approach to tunneling splittings using saddle-point normal coordinates. J Phys Chem A (2009) 0.75
Effect of Microstructure on the Radioluminescence and Transparency of Ce-Doped Strontium Hafnate Ceramics. Opt Mater (Amst) (2010) 0.75
Narrow-band, widely electronically tuned frequency-shifted feedback laser. Opt Lett (2002) 0.75
Downregulation of BM88 after optic nerve injury. Invest Ophthalmol Vis Sci (2014) 0.75
A combined experimental and computational study on the ionization energies of the cyclic and linear C3H isomers. Chemphyschem (2007) 0.75
Surgical correction of orbital and periorbital deformities using lamella and complex osteotomies in both orbital rim and wall. J Craniofac Surg (2005) 0.75
Corrigendum: Genetic Variants Identified from Epilepsy of Unknown Etiology in Chinese Children by Targeted Exome Sequencing. Sci Rep (2017) 0.75
Communication: quasiclassical trajectory calculations of correlated product-state distributions for the dissociation of (H2O)2 and (D2O)2. J Chem Phys (2011) 0.75
Communication: a chemically accurate global potential energy surface for the HO + CO → H + CO2 reaction. J Chem Phys (2012) 0.75
Quantum vibrational analysis and infrared spectra of microhydrated sodium ions using an ab initio potential. J Chem Phys (2011) 0.75
Role of polyphenols in plant-mediated synthesis of gold nanoparticles: identification of active components and their functional mechanism. Nanotechnology (2020) 0.75