Published in Clin Chem on January 01, 2007
High resolution melting applications for clinical laboratory medicine. Exp Mol Pathol (2008) 1.92
A rapid high-throughput method for the detection and quantification of RNA editing based on high-resolution melting of amplicons. Nucleic Acids Res (2007) 1.62
A rapid and efficient method of genotyping zebrafish mutants. Dev Dyn (2009) 1.23
Base-pair neutral homozygotes can be discriminated by calibrated high-resolution melting of small amplicons. Nucleic Acids Res (2008) 1.19
High resolution melting analysis for gene scanning. Methods (2010) 1.14
Validation of high-resolution DNA melting analysis for mutation scanning of the cystic fibrosis transmembrane conductance regulator (CFTR) gene. J Mol Diagn (2008) 1.03
Multiplex amplicon genotyping by high-resolution melting. J Biomol Tech (2009) 0.99
Is high resolution melting analysis (HRMA) accurate for detection of human disease-associated mutations? A meta analysis. PLoS One (2011) 0.90
Automated Classification and Cluster Visualization of Genotypes Derived from High Resolution Melt Curves. PLoS One (2015) 0.75
The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments. Clin Chem (2009) 40.90
Next-generation sequencing: from basic research to diagnostics. Clin Chem (2009) 4.18
Assuring the quality of next-generation sequencing in clinical laboratory practice. Nat Biotechnol (2012) 3.62
High-resolution DNA melting analysis for simple and efficient molecular diagnostics. Pharmacogenomics (2007) 3.52
The digital MIQE guidelines: Minimum Information for Publication of Quantitative Digital PCR Experiments. Clin Chem (2013) 3.38
Amplicon DNA melting analysis for mutation scanning and genotyping: cross-platform comparison of instruments and dyes. Clin Chem (2006) 3.24
Sensitivity and specificity of single-nucleotide polymorphism scanning by high-resolution melting analysis. Clin Chem (2004) 2.91
Amplicon melting analysis with labeled primers: a closed-tube method for differentiating homozygotes and heterozygotes. Clin Chem (2003) 2.91
Closed-tube genotyping with unlabeled oligonucleotide probes and a saturating DNA dye. Clin Chem (2004) 2.57
High-resolution DNA melting analysis for simultaneous mutation scanning and genotyping in solution. Clin Chem (2005) 2.55
Simultaneous mutation scanning and genotyping by high-resolution DNA melting analysis. Nat Protoc (2007) 2.16
High resolution melting applications for clinical laboratory medicine. Exp Mol Pathol (2008) 1.92
College of American Pathologists' laboratory standards for next-generation sequencing clinical tests. Arch Pathol Lab Med (2014) 1.84
Expanded instrument comparison of amplicon DNA melting analysis for mutation scanning and genotyping. Clin Chem (2007) 1.73
Real-time PCR technology for cancer diagnostics. Clin Chem (2002) 1.61
Guidelines for the diagnosis and monitoring of paroxysmal nocturnal hemoglobinuria and related disorders by flow cytometry. Cytometry B Clin Cytom (2010) 1.61
The need for transparency and good practices in the qPCR literature. Nat Methods (2013) 1.58
Opportunities and challenges associated with clinical diagnostic genome sequencing: a report of the Association for Molecular Pathology. J Mol Diagn (2012) 1.57
High-resolution DNA melting analysis in clinical research and diagnostics. Expert Rev Mol Diagn (2010) 1.54
Family clusters of variant X-linked chronic granulomatous disease. Pediatr Infect Dis J (2009) 1.52
Quantitative heteroduplex analysis for single nucleotide polymorphism genotyping. Anal Biochem (2005) 1.45
A comparison of high-resolution melting analysis with denaturing high-performance liquid chromatography for mutation scanning: cystic fibrosis transmembrane conductance regulator gene as a model. Am J Clin Pathol (2005) 1.44
Distinguishing different DNA heterozygotes by high-resolution melting. Clin Chem (2005) 1.38
Primer sequence disclosure: a clarification of the MIQE guidelines. Clin Chem (2011) 1.32
uMELT: prediction of high-resolution melting curves and dynamic melting profiles of PCR products in a rich web application. Bioinformatics (2011) 1.27
Multiple endocrine neoplasia type 2 RET protooncogene database: repository of MEN2-associated RET sequence variation and reference for genotype/phenotype correlations. Hum Mutat (2009) 1.27
Scanning the cystic fibrosis transmembrane conductance regulator gene using high-resolution DNA melting analysis. Clin Chem (2007) 1.26
Unlabeled oligonucleotides as internal temperature controls for genotyping by amplicon melting. J Mol Diagn (2007) 1.23
Germline mutations in NFKB2 implicate the noncanonical NF-κB pathway in the pathogenesis of common variable immunodeficiency. Am J Hum Genet (2013) 1.23
A rapid and efficient method of genotyping zebrafish mutants. Dev Dyn (2009) 1.23
LightCycler technology in molecular diagnostics. J Mol Diagn (2009) 1.21
A novel germline PIGA mutation in Ferro-Cerebro-Cutaneous syndrome: a neurodegenerative X-linked epileptic encephalopathy with systemic iron-overload. Am J Med Genet A (2013) 1.20
Base-pair neutral homozygotes can be discriminated by calibrated high-resolution melting of small amplicons. Nucleic Acids Res (2008) 1.19
Quadruplex genotyping of F5, F2, and MTHFR variants in a single closed tube by high-resolution amplicon melting. Clin Chem (2007) 1.17
Mycobacterium chelonae-abscessus complex associated with sinopulmonary disease, Northeastern USA. Emerg Infect Dis (2011) 1.16
High resolution melting analysis for gene scanning. Methods (2010) 1.14
Evaluation of quantification methods for real-time PCR minor groove binding hybridization probe assays. Anal Biochem (2006) 1.14
Mutation scanning of the RET protooncogene using high-resolution melting analysis. Clin Chem (2006) 1.14
Spinning disk platform for microfluidic digital polymerase chain reaction. Anal Chem (2010) 1.09
Characterization of aberrant melting peaks in unlabeled probe assays. J Mol Diagn (2007) 1.09
Comparison of the Illumina Genome Analyzer and Roche 454 GS FLX for resequencing of hypertrophic cardiomyopathy-associated genes. J Biomol Tech (2010) 1.09
Rapid diagnosis of MEN2B using unlabeled probe melting analysis and the LightCycler 480 instrument. J Mol Diagn (2008) 1.06
A direct comparison of next generation sequencing enrichment methods using an aortopathy gene panel- clinical diagnostics perspective. BMC Med Genomics (2012) 1.05
Detection of c-kit-activating mutations in gastrointestinal stromal tumors by high-resolution amplicon melting analysis. Am J Clin Pathol (2004) 1.04
Rapid species identification within the Mycobacterium chelonae-abscessus group by high-resolution melting analysis of hsp65 PCR products. Am J Clin Pathol (2005) 1.02
Identifying common genetic variants by high-resolution melting. Clin Chem (2007) 1.00
Multiplex amplicon genotyping by high-resolution melting. J Biomol Tech (2009) 0.99
Unlabeled oligonucleotide probes modified with locked nucleic acids for improved mismatch discrimination in genotyping by melting analysis. Biotechniques (2005) 0.99
Multiplex single-color PCR with amplicon melting analysis for identification of Aspergillus species. Clin Chem (2006) 0.99
Multi-sample pooling and illumina genome analyzer sequencing methods to determine gene sequence variation for database development. J Biomol Tech (2010) 0.98
Developing genome and exome sequencing for candidate gene identification in inherited disorders: an integrated technical and bioinformatics approach. Arch Pathol Lab Med (2012) 0.96
Unlabeled probes for the detection and typing of herpes simplex virus. Clin Chem (2007) 0.96
Molecular classification of melanoma using real-time quantitative reverse transcriptase-polymerase chain reaction. Cancer (2005) 0.96
Fifty years of molecular (DNA/RNA) diagnostics. Clin Chem (2005) 0.96
Homogeneous amplification and mutation scanning of the p53 gene using fluorescent melting curves. Clin Chem (2002) 0.94
Clinical analysis of genome next-generation sequencing data using the Omicia platform. Expert Rev Mol Diagn (2013) 0.93
Rapid genetic analysis of x-linked chronic granulomatous disease by high-resolution melting. J Mol Diagn (2010) 0.92
Mathematical algorithms for high-resolution DNA melting analysis. Methods Enzymol (2009) 0.91
Comparison of two quantitative polymerase chain reaction methods for detecting HER2/neu amplification. J Mol Diagn (2003) 0.91
Snapback primer genotyping with saturating DNA dye and melting analysis. Clin Chem (2008) 0.91
RET proto-oncogene genotyping using unlabeled probes, the masking technique, and amplicon high-resolution melting analysis. J Mol Diagn (2007) 0.91
Masking selected sequence variation by incorporating mismatches into melting analysis probes. Hum Mutat (2006) 0.90
Identification of patients with RAG mutations previously diagnosed with common variable immunodeficiency disorders. J Clin Immunol (2014) 0.89
Extraction and amplification of genomic DNA from human blood on nanoporous aluminum oxide membranes. Clin Chem (2004) 0.89
Closed-tube genotyping of apolipoprotein E by isolated-probe PCR with multiple unlabeled probes and high-resolution DNA melting analysis. Biotechniques (2007) 0.89
Variant identification in multi-sample pools by illumina genome analyzer sequencing. J Biomol Tech (2011) 0.88
uAnalyze: web-based high-resolution DNA melting analysis with comparison to thermodynamic predictions. IEEE/ACM Trans Comput Biol Bioinform (2013) 0.88
Molecular diagnostics: at the cutting edge of translational research. Clin Chem (2009) 0.84
Genotyping hepatitis C virus by heteroduplex mobility analysis using temperature gradient capillary electrophoresis. J Clin Microbiol (2004) 0.84
Human papillomavirus genotyping using an automated film-based chip array. J Mol Diagn (2009) 0.83
Mycobacterium tuberculosis complex differentiation by genomic deletion patterns with multiplex polymerase chain reaction and melting analysis. Diagn Microbiol Infect Dis (2010) 0.83
Evaluation of Her-2/neu gene status in osteosarcoma by fluorescence in situ hybridization and multiplex and monoplex polymerase chain reactions. Arch Pathol Lab Med (2006) 0.83
Enrichment and detection of rare alleles by means of snapback primers and rapid-cycle PCR. Clin Chem (2010) 0.82
Stopped-flow DNA polymerase assay by continuous monitoring of dNTP incorporation by fluorescence. Anal Biochem (2013) 0.82
TACI mutation p.Lys154Ter identified in Good Syndrome. Clin Immunol (2012) 0.82
Localization and imaging of nucleic acids on nanoporous aluminum oxide membranes. Clin Chem (2004) 0.82