A novel cancer therapy approach targeting microtubule function.

Inhibiting proliferation and enhancing chemosensitivity to taxanes in osteosarcoma cells by RNA interference-mediated downregulation of stathmin expression. Mol Med (2007) 1.01

Mechanism for the catastrophe-promoting activity of the microtubule destabilizer Op18/stathmin. Proc Natl Acad Sci U S A (2013) 0.97

Silencing stathmin gene expression by survivin promoter-driven siRNA vector to reverse malignant phenotype of tumor cells. Cancer Biol Ther (2006) 1.60

Mechanochemical model of microtubule structure and self-assembly kinetics. Biophys J (2005) 2.31

Estimates of lateral and longitudinal bond energies within the microtubule lattice. Proc Natl Acad Sci U S A (2002) 2.25

Centrosome maturation: measurement of microtubule nucleation throughout the cell cycle by using GFP-tagged EB1. Proc Natl Acad Sci U S A (2004) 2.21

The formin mDia2 stabilizes microtubules independently of its actin nucleation activity. J Cell Biol (2008) 1.96

Organization and dynamics of growing microtubule plus ends during early mitosis. Mol Biol Cell (2003) 1.75

Regulation of microtubule dynamics by Bim1 and Bik1, the budding yeast members of the EB1 and CLIP-170 families of plus-end tracking proteins. Mol Biol Cell (2010) 1.05

Dissecting the nanoscale distributions and functions of microtubule-end-binding proteins EB1 and ch-TOG in interphase HeLa cells. PLoS One (2012) 1.05

Human EFO1p exhibits acetyltransferase activity and is a unique combination of linker histone and Ctf7p/Eco1p chromatid cohesion establishment domains. Nucleic Acids Res (2003) 1.05

Infection with replication-deficient adenovirus induces changes in the dynamic instability of host cell microtubules. Mol Biol Cell (2006) 1.02

Identification of a novel tubulin-destabilizing protein related to the chaperone cofactor E. J Cell Sci (2005) 1.01

Stathmin regulates centrosomal nucleation of microtubules and tubulin dimer/polymer partitioning. Mol Biol Cell (2009) 1.00

Cellular entry and nuclear targeting by a highly anionic molecular umbrella. Bioconjug Chem (2008) 0.97

An unexplained sequestration of latrunculin A is required in neutrophils for inhibition of actin polymerization. Cell Motil Cytoskeleton (2002) 0.97

Autonomous and phosphorylation-responsive microtubule-regulating activities of the N-terminus of Op18/stathmin. J Cell Sci (2003) 0.90

The microtubule cytoskeleton is required for a G2 cell cycle delay in cancer cells lacking stathmin and p53. Cytoskeleton (Hoboken) (2012) 0.89

Stathmin/oncoprotein 18, a microtubule regulatory protein, is required for survival of both normal and cancer cell lines lacking the tumor suppressor, p53. Cancer Biol Ther (2010) 0.87

The contributions of microtubule stability and dynamic instability to adenovirus nuclear localization efficiency. Cell Motil Cytoskeleton (2007) 0.86

Stathmin and microtubules regulate mitotic entry in HeLa cells by controlling activation of both Aurora kinase A and Plk1. Mol Biol Cell (2013) 0.82

Gene expression profiles in mouse embryo fibroblasts lacking stathmin, a microtubule regulatory protein, reveal changes in the expression of genes contributing to cell motility. BMC Genomics (2009) 0.81

Cytoskeleton: microtubules born on the run. Curr Biol (2005) 0.77

Positional analyses of BRCA1-dependent expression in Saccharomyces cerevisiae. Cell Cycle (2008) 0.77

Reversible action of diaminothiazoles in cancer cells is implicated by the induction of a fast conformational change of tubulin and suppression of microtubule dynamics. Mol Cancer Ther (2013) 0.76

A delay prior to mitotic entry triggers caspase 8-dependent cell death in p53-deficient Hela and HCT-116 cells. Cell Cycle (2015) 0.75

Q & A: Lynne Cassimeris. Interview. Curr Biol (2006) 0.75