Differential neuroprotective effects of a minocycline-based drug cocktail in transient and permanent focal cerebral ischemia.

PubWeight™: 1.00‹?› | Rank: Top 15%

🔗 View Article (PMID 17234187)

Published in Exp Neurol on January 17, 2007

Authors

Yuan Cheng Weng1, Jasna Kriz

Author Affiliations

1: Faculty of Medicine, Laval University, Centre de Recherche du CHUL (CHUQ), Department of Anatomy and Physiology, T3-67, 2705, boul. Laurier, Quebec, QC, Canada G1V 4G2.

Articles citing this

Microglial responses after ischemic stroke and intracerebral hemorrhage. Clin Dev Immunol (2013) 1.43

Selection of reference genes for quantitative real-time PCR in a rat asphyxial cardiac arrest model. BMC Mol Biol (2008) 1.39

Minocycline development for acute ischemic stroke. Transl Stroke Res (2011) 1.12

Attenuation of acute stroke injury in rat brain by minocycline promotes blood-brain barrier remodeling and alternative microglia/macrophage activation during recovery. J Neuroinflammation (2015) 1.01

Riluzole increases the amount of latent HSF1 for an amplified heat shock response and cytoprotection. PLoS One (2008) 0.96

A3 adenosine receptor agonist reduces brain ischemic injury and inhibits inflammatory cell migration in rats. Am J Pathol (2011) 0.91

The effect of right vagus nerve stimulation on focal cerebral ischemia: an experimental study in the rat. Brain Stimul (2011) 0.89

Modulation of inflammatory responses after global ischemia by transplanted umbilical cord matrix stem cells. Stem Cells (2008) 0.85

Loss of neuron-astroglial interaction rapidly induces protective CNTF expression after stroke in mice. J Neurosci (2012) 0.85

Effect of Antibiotic Class on Stroke Outcome. Stroke (2015) 0.83

Influence of inflammation on poststroke plasticity. Neural Plast (2013) 0.80

A novel method for inducing focal ischemia in vitro. J Neurosci Methods (2010) 0.80

Translational potential of astrocytes in brain disorders. Prog Neurobiol (2015) 0.80

Molecular imaging of nestin in neuroinflammatory conditions reveals marked signal induction in activated microglia. J Neuroinflammation (2017) 0.78

Regulatory effect of Dimethyl Sulfoxide (DMSO) on astrocytic reactivity in a murine model of cerebral infarction by arterial embolization. Colomb Med (Cali) (2013) 0.77

Classification Framework and Chemical Biology of Tetracycline-Structure-Based Drugs. Antibiotics (Basel) (2012) 0.75

Articles by these authors

Selective ablation of proliferating microglial cells exacerbates ischemic injury in the brain. J Neurosci (2007) 3.93

Microglial response to gold nanoparticles. ACS Nano (2010) 1.86

Deregulation of TDP-43 in amyotrophic lateral sclerosis triggers nuclear factor κB-mediated pathogenic pathways. J Exp Med (2011) 1.46

Pathological hallmarks of amyotrophic lateral sclerosis/frontotemporal lobar degeneration in transgenic mice produced with TDP-43 genomic fragments. Brain (2011) 1.33

Live imaging of neuroinflammation reveals sex and estrogen effects on astrocyte response to ischemic injury. Stroke (2008) 1.24

Cell cycle regulators in the neuronal death pathway of amyotrophic lateral sclerosis caused by mutant superoxide dismutase 1. J Neurosci (2003) 1.19

Galectin-3 is required for resident microglia activation and proliferation in response to ischemic injury. J Neurosci (2012) 1.16

Live imaging of amyotrophic lateral sclerosis pathogenesis: disease onset is characterized by marked induction of GFAP in Schwann cells. Glia (2009) 1.12

Transgenic mouse models of amyotrophic lateral sclerosis. Biochim Biophys Acta (2006) 1.11

Treatment with minocycline after disease onset alters astrocyte reactivity and increases microgliosis in SOD1 mutant mice. Exp Neurol (2010) 1.05

Real-time imaging of astrocyte response to quantum dots: in vivo screening model system for biocompatibility of nanoparticles. Nano Lett (2007) 0.99

Brain-derived neurotrophic factor promotes vasculature-associated migration of neuronal precursors toward the ischemic striatum. PLoS One (2013) 0.97

Toll-like receptor 2 deficiency leads to delayed exacerbation of ischemic injury. J Neuroinflammation (2012) 0.96

PCSK9 reduces the protein levels of the LDL receptor in mouse brain during development and after ischemic stroke. J Lipid Res (2011) 0.93

Involvement of TLR2 in recognition of acute gammaherpesvirus-68 infection. PLoS One (2010) 0.93

Accumulation of dietary docosahexaenoic acid in the brain attenuates acute immune response and development of postischemic neuronal damage. Stroke (2011) 0.91

Mouse model of intraluminal MCAO: cerebral infarct evaluation by cresyl violet staining. J Vis Exp (2012) 0.90

Induction of peripherin expression in subsets of brain neurons after lesion injury or cerebral ischemia. Brain Res (2002) 0.88

Real-time imaging after cerebral ischemia: model systems for visualization of inflammation and neuronal repair. Methods Enzymol (2012) 0.85

Als2 mRNA splicing variants detected in KO mice rescue severe motor dysfunction phenotype in Als2 knock-down zebrafish. Hum Mol Genet (2008) 0.85

Pathways to motor neuron degeneration in transgenic mouse models. Biochimie (2002) 0.85

The role of the MYD88-dependent pathway in MPTP-induced brain dopaminergic degeneration. J Neuroinflammation (2011) 0.84

Abnormal regenerative responses and impaired axonal outgrowth after nerve crush in TDP-43 transgenic mouse models of amyotrophic lateral sclerosis. J Neurosci (2012) 0.81

Lipopolysaccharide-QD micelles induce marked induction of TLR2 and lipid droplet accumulation in olfactory bulb microglia. Mol Pharm (2010) 0.81

Cytoskeletal defects in amyotrophic lateral sclerosis (motor neuron disease). Novartis Found Symp (2005) 0.81

Model system for live imaging of neuronal responses to injury and repair. Mol Imaging (2011) 0.80

Distinct biochemical signatures characterize peripherin isoform expression in both traumatic neuronal injury and motor neuron disease. J Neurochem (2010) 0.79

Early-stage treatment with Withaferin A reduces levels of misfolded superoxide dismutase 1 and extends lifespan in a mouse model of amyotrophic lateral sclerosis. Neurotherapeutics (2015) 0.79

Chapter 6 Animal models of motor neuron death. Handb Clin Neurol (2007) 0.75