PubRank

Dimitrios Tsikas

Author PubWeight™ 114.12‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Urinary 8-iso-prostaglandin F2alpha as a risk marker in patients with coronary heart disease: a matched case-control study. Circulation 2004 2.20
2 Endothelial nitric oxide synthase uncoupling impairs endothelial progenitor cell mobilization and function in diabetes. Diabetes 2007 2.12
3 Cardiovascular effects of systemic nitric oxide synthase inhibition with asymmetrical dimethylarginine in humans. Circulation 2003 2.12
4 Suppression of endothelial progenitor cells in human coronary artery disease by the endogenous nitric oxide synthase inhibitor asymmetric dimethylarginine. J Am Coll Cardiol 2005 1.99
5 Endothelial dysfunction and raised plasma concentrations of asymmetric dimethylarginine in pregnant women who subsequently develop pre-eclampsia. Lancet 2003 1.84
6 ADMA and oxidative stress are responsible for endothelial dysfunction in hyperhomocyst(e)inemia: effects of L-arginine and B vitamins. Cardiovasc Res 2003 1.78
7 Angiotensin II receptor-independent antiinflammatory and antiaggregatory properties of losartan: role of the active metabolite EXP3179. Circ Res 2002 1.71
8 Bone marrow molecular alterations after myocardial infarction: Impact on endothelial progenitor cells. Cardiovasc Res 2006 1.65
9 Age-dependent impairment of endothelial progenitor cells is corrected by growth-hormone-mediated increase of insulin-like growth-factor-1. Circ Res 2007 1.61
10 Oxidative stress and human diseases: Origin, link, measurement, mechanisms, and biomarkers. Crit Rev Clin Lab Sci 2009 1.60
11 Quantification of arginine and its mono- and dimethylated analogs NMMA, ADMA and SDMA in biological fluids by LC-MS/MS: Is LC superfluous? J Chromatogr B Analyt Technol Biomed Life Sci 2009 1.39
12 Nitric oxide synthesis in chronic renal failure. Are plasma S-nitrosothiol levels elevated? Clin Chim Acta 2004 1.38
13 Assessment of nitric oxide biosynthesis and peroxynitrite formation within the central nervous system by measuring L-citrulline in the cerebrospinal fluid? J Chromatogr B Analyt Technol Biomed Life Sci 2004 1.38
14 Signal transducer and activator of transcription 3-mediated regulation of miR-199a-5p links cardiomyocyte and endothelial cell function in the heart: a key role for ubiquitin-conjugating enzymes. Eur Heart J 2010 1.14
15 Endothelial nitric oxide synthase, cyclooxygenase-2, and essential hypertension: is there an interaction? Hypertension 2013 1.11
16 Can nitric oxide synthase activity be unequivocally measured in red Blood cells and platelets? if yes, by which assay? Redox Biol 2015 1.08
17 Improvement in left ventricular remodeling by the endothelial nitric oxide synthase enhancer AVE9488 after experimental myocardial infarction. Circulation 2008 1.07
18 Developmental changes in the L-arginine/nitric oxide pathway from infancy to adulthood: plasma asymmetric dimethylarginine levels decrease with age. Clin Chem Lab Med 2007 1.05
19 Quantification of endocannabinoids in biological systems by chromatography and mass spectrometry: a comprehensive review from an analytical and biological perspective. Biochim Biophys Acta 2011 1.05
20 Chronic angiotensin II receptor blockade reduces (intra)renal vascular resistance in patients with type 2 diabetes. J Am Soc Nephrol 2005 1.04
21 Clostridium difficile toxins A and B directly stimulate human mast cells. Infect Immun 2007 0.97
22 Simultaneous UPLC-MS/MS quantification of the endocannabinoids 2-arachidonoyl glycerol (2AG), 1-arachidonoyl glycerol (1AG), and anandamide in human plasma: minimization of matrix-effects, 2AG/1AG isomerization and degradation by toluene solvent extraction. J Chromatogr B Analyt Technol Biomed Life Sci 2011 0.96
23 Growth hormone treatment improves markers of systemic nitric oxide bioavailability via insulin-like growth factor-I. J Clin Endocrinol Metab 2007 0.95
24 Transcoronary delivery of bone marrow cells to the infarcted murine myocardium: feasibility, cellular kinetics, and improvement in cardiac function. Basic Res Cardiol 2006 0.94
25 Pathogenic cycle between the endogenous nitric oxide synthase inhibitor asymmetrical dimethylarginine and the leukocyte-derived hemoprotein myeloperoxidase. Circulation 2011 0.93
26 Measurement of physiological S-nitrosothiols: a problem child and a challenge. Nitric Oxide 2003 0.92
27 Oxidative damage in clinical ischemia/reperfusion injury: a reappraisal. Antioxid Redox Signal 2013 0.92
28 Asymmetric dimethylarginine (ADMA) in human blood: effects of extended haemodialysis in the critically ill patient with acute kidney injury, protein binding to human serum albumin and proteolysis by thermolysin. Amino Acids 2015 0.91
29 Endothelial dysfunction in patients with peripheral arterial disease and chronic hyperhomocysteinemia: potential role of ADMA. Vasc Med 2004 0.90
30 Bronchial epithelial cell-derived prostaglandin E2 dampens the reactivity of dendritic cells. J Immunol 2011 0.87
31 Human plasma concentrations of malondialdehyde (MDA) and the F2-isoprostane 15(S)-8-iso-PGF(2alpha) may be markedly compromised by hemolysis: evidence by GC-MS/MS and potential analytical and biological ramifications. Clin Biochem 2009 0.86
32 Doubts concerning functional endothelial nitric oxide synthase in human erythrocytes. Blood 2012 0.86
33 Rapeseed protein in a high-fat mixed meal alleviates postprandial systemic and vascular oxidative stress and prevents vascular endothelial dysfunction in healthy rats. J Nutr 2009 0.86
34 In vitro effects of a novel class of nitric oxide (NO) donating compounds on isolated human erectile tissue. Eur Urol 2002 0.86
35 Targeted stable-isotope dilution GC-MS/MS analysis of the endocannabinoid anandamide and other fatty acid ethanol amides in human plasma. J Chromatogr B Analyt Technol Biomed Life Sci 2009 0.85
36 Effects of successive air and nitrox dives on human vascular function. Eur J Appl Physiol 2011 0.85
37 Effects of various nitric oxide-donating drugs on adrenergic tension of human seminal vesicles in vitro. Urology 2003 0.84
38 Resveratrol protects against atherosclerosis, but does not add to the antiatherogenic effect of atorvastatin, in APOE*3-Leiden.CETP mice. J Nutr Biochem 2013 0.84
39 Effects of specific COX-2-inhibition on renin release and renal and systemic prostanoid synthesis in healthy volunteers. Kidney Int 2005 0.84
40 Nitric oxide, peroxynitrite, S-nitrosothiols and thiols are unlikely to exert their effects on recombinant cyclooxygenase-1 and cyclooxygenase-2 activity in vitro by modifying cysteine moieties. Nitric Oxide 2012 0.84
41 N-Acetylcysteine ethyl ester (NACET): a novel lipophilic cell-permeable cysteine derivative with an unusual pharmacokinetic feature and remarkable antioxidant potential. Biochem Pharmacol 2012 0.84
42 A validated, rapid UPLC-MS/MS method for simultaneous ivabradine, reboxetine, and metoprolol analysis in human plasma and its application to clinical trial samples. J Chromatogr B Analyt Technol Biomed Life Sci 2013 0.83
43 Stable-isotope dilution GC-MS approach for nitrite quantification in human whole blood, erythrocytes, and plasma using pentafluorobenzyl bromide derivatization: nitrite distribution in human blood. J Chromatogr B Analyt Technol Biomed Life Sci 2010 0.83
44 High-performance liquid chromatography ultraviolet assay for human erythrocytic catalase activity by measuring glutathione as o-phthalaldehyde derivative. Anal Biochem 2010 0.83
45 Influence of dietary fat intake on the endocannabinoid system in lean and obese subjects. Obesity (Silver Spring) 2014 0.82
46 Specific transport of S-nitrosocysteine in human red blood cells: Implications for formation of S-nitrosothiols and transport of NO bioactivity within the vasculature. FEBS Lett 2005 0.82
47 Asymmetric dimethylarginine (ADMA)--a modulator of nociception in opiate tolerance and addiction? Nitric Oxide 2007 0.82
48 Quantification of acetaminophen (paracetamol) in human plasma and urine by stable isotope-dilution GC-MS and GC-MS/MS as pentafluorobenzyl ether derivative. J Chromatogr B Analyt Technol Biomed Life Sci 2011 0.81
49 Comments on "Determination of S-nitrosoglutathione and other nitrosothiols by p-hydroxymercurybenzoate derivatization and reverse phase chromatography coupled with chemical vapor generation atomic fluorescence detection" by Bramanti et al. Talanta 2009 0.81
50 Elevated asymmetric dimethylarginine (ADMA) and inverse correlation between circulating ADMA and glomerular filtration rate in children with sporadic focal segmental glomerulosclerosis (FSGS). Nephrol Dial Transplant 2008 0.81
51 Hypercholesterolemia impairs basal nitric oxide synthase turnover rate: a study investigating the conversion of L-[guanidino-(15)N(2)]-arginine to (15)N-labeled nitrate by gas chromatography--mass spectrometry. Nitric Oxide 2004 0.81
52 Urinary asymmetric dimethylarginine (ADMA) is a predictor of mortality risk in patients with coronary artery disease. Int J Cardiol 2010 0.81
53 A review and discussion of platelet nitric oxide and nitric oxide synthase: do blood platelets produce nitric oxide from L-arginine or nitrite? Amino Acids 2015 0.81
54 Changes of blood endocannabinoids during anaesthesia: a special case for fatty acid amide hydrolase inhibition by propofol? Br J Clin Pharmacol 2012 0.80
55 Positive correlation between plasma nitrite and performance during high-intensive exercise but not oxidative stress in healthy men. Nitric Oxide 2010 0.80
56 Biosynthesis of homoarginine (hArg) and asymmetric dimethylarginine (ADMA) from acutely and chronically administered free L-arginine in humans. Amino Acids 2015 0.80
57 Lack of oxidative stress during sustained therapy with isosorbide dinitrate and pentaerythrityl tetranitrate in healthy humans: a randomized, double-blind crossover study. J Cardiovasc Pharmacol 2003 0.80
58 Trouble with the analysis of nitrite, nitrate, S-nitrosothiols and 3-nitrotyrosine: freezing-induced artifacts? Nitric Oxide 2004 0.80
59 Effects of carvedilol on oxidative stress in human endothelial cells and healthy volunteers. Eur J Clin Pharmacol 2004 0.79
60 S-Nitrosothiols in blood: does photosensitivity explain a 4-order-of-magnitude concentration range? Clin Chem 2009 0.79
61 The L-arginine/NO pathway and homoarginine are altered in Duchenne muscular dystrophy and improved by glucocorticoids. Amino Acids 2015 0.79
62 Stable isotope liquid chromatography-tandem mass spectrometry assay for fatty acid amide hydrolase activity. Anal Biochem 2011 0.79
63 Plasma ADMA associates with all-cause mortality in renal transplant recipients. Amino Acids 2015 0.79
64 Free iron ions decrease indoleamine 2,3-dioxygenase expression and reduce IFNgamma-induced inhibition of Chlamydia trachomatis infection. Microb Pathog 2009 0.79
65 Elevated plasma and urine levels of ADMA and 15(S)-8-iso-PGF2alpha in end-stage liver disease. Hepatology 2003 0.79
66 Renal carbonic anhydrases are involved in the reabsorption of endogenous nitrite. Nitric Oxide 2012 0.79
67 Acetylsalicylic acid inhibits monocyte adhesion to endothelial cells by an antioxidative mechanism. J Cardiovasc Pharmacol 2004 0.79
68 Asymmetric dimethylarginine in children with homocystinuria or phenylketonuria. Amino Acids 2011 0.78
69 HPLC analysis of human erythrocytic glutathione forms using OPA and N-acetyl-cysteine ethyl ester: evidence for nitrite-induced GSH oxidation to GSSG. J Chromatogr B Analyt Technol Biomed Life Sci 2009 0.78
70 Increased asymmetric dimethylarginine (ADMA) dimethylaminohydrolase (DDAH) activity in childhood hypercholesterolemia type II. Amino Acids 2011 0.78
71 Enhanced human tissue microdialysis using hydroxypropyl-ß-cyclodextrin as molecular carrier. PLoS One 2013 0.78
72 GC-MS assay for hepatic DDAH activity in diabetic and non-diabetic rats by measuring dimethylamine (DMA) formed from asymmetric dimethylarginine (ADMA): evaluation of the importance of S-nitrosothiols as inhibitors of DDAH activity in vitro and in vivo in humans. J Chromatogr B Analyt Technol Biomed Life Sci 2007 0.78
73 Plasma nitrite concentration decreases after hyperoxia-induced oxidative stress in healthy humans. Clin Physiol Funct Imaging 2012 0.78
74 Role of carbon monoxide and nitric oxide in adult rat hepatocytes proliferating in vitro: Effects of CAS 1609. Nitric Oxide 2010 0.78
75 Pitfalls in the measurement of tissue DDAH activity: is DDAH sensitive to nitrosative and oxidative stress? Kidney Int 2008 0.77
76 Local nitric oxide levels reflect the degree of allergic airway inflammation after segmental allergen challenge in asthmatics. Nitric Oxide 2005 0.77
77 Accurate quantification of dimethylamine (DMA) in human plasma and serum by GC-MS and GC-tandem MS as pentafluorobenzamide derivative in the positive-ion chemical ionization mode. J Chromatogr B Analyt Technol Biomed Life Sci 2007 0.77
78 Peripheral endocannabinoid microdialysis: in vitro characterization and proof-of-concept in human subjects. Anal Bioanal Chem 2012 0.77
79 Methodological considerations on the detection of 3-nitrotyrosine in the cardiovascular system. Circ Res 2002 0.77
80 Application of a stable-isotope dilution technique to study the pharmacokinetics of human 15N-labelled S-nitrosoalbumin in the rat: possible mechanistic and biological implications. J Chromatogr B Analyt Technol Biomed Life Sci 2008 0.77
81 Measurement of nitrotyrosine in plasma by immunoassays is fraught with danger: commercial availability is no guarantee of analytical reliability. Clin Chem Lab Med 2010 0.77
82 Plasma homoarginine, arginine, asymmetric dimethylarginine and total homocysteine interrelationships in rheumatoid arthritis, coronary artery disease and peripheral artery occlusion disease. Amino Acids 2015 0.77
83 Elevated dimethylarginine dimethylaminohydrolase (DDAH) activity in rheumatoid arthritis and spondyloarthritis. Nitric Oxide 2011 0.77
84 Tetrahydrobiopterin and endothelial nitric oxide synthase uncoupling. Hypertension 2012 0.77
85 Elevated urinary excretion of nitric oxide metabolites in young infants with Zellweger syndrome. Clin Chim Acta 2003 0.77
86 DDAH activity is not associated with oxidative stress in elderly patients with peripheral arterial occlusive disease. Exp Gerontol 2014 0.77
87 Measurement and diagnostic use of hepatic cytochrome P450 metabolism of oleic acid in liver disease. Liver Int 2010 0.77
88 Clinical-chemistry laboratory relevant hemolysis is unlikely to compromise human plasma concentration of free asymmetric dimethylarginine (ADMA). Clin Biochem 2012 0.77
89 S-nitrosoalbumin and other S-nitrosothiols in the blood: is their quantity of no relevance? Circ Res 2004 0.77
90 Quantification of N-(3-chloro-2-hydroxypropyl)valine in human haemoglobin as a biomarker of epichlorohydrin exposure by gas chromatography-tandem mass spectrometry with stable-isotope dilution. J Chromatogr B Analyt Technol Biomed Life Sci 2008 0.77
91 Enhanced NO signaling in patients with Takotsubo cardiomyopathy: short-term pain, long-term gain? Cardiovasc Drugs Ther 2013 0.77
92 Unique pentafluorobenzylation and collision-induced dissociation for specific and accurate GC-MS/MS quantification of the catecholamine metabolite 3,4-dihydroxyphenylglycol (DHPG) in human urine. J Chromatogr B Analyt Technol Biomed Life Sci 2010 0.76
93 Nitric oxide and hypertension. J Hypertens 2012 0.76
94 Asymmetrical dimethylarginine, oxidative stress, and atherosclerosis. Hypertension 2011 0.76
95 Comment on: Ott et al. Reduction in basal nitric oxide activity causes albuminuria. Diabetes 2011;60:572-576. Diabetes 2011 0.76
96 9- and 10-Nitro-oleic acid do not interfere with the GC-MS quantitative determination of nitrite and nitrate in biological fluids when measured as their pentafluorobenzyl derivatives. J Chromatogr B Analyt Technol Biomed Life Sci 2007 0.76
97 Inhibition of proteasome-mediated glucocorticoid receptor degradation restores nitric oxide bioavailability in myocardial endothelial cells in vitro. Biol Cell 2014 0.76
98 Severe glycerol intoxication after Menière's disease diagnostic--case report and overview of kinetic data. Clin Toxicol (Phila) 2009 0.76
99 Human hemoglobin does not contain asymmetric dimethylarginine (ADMA). Nitric Oxide 2012 0.76
100 Potential problems and pitfalls with the use of S-nitrosoglutathione and other S-nitrosothiols in physiology-oriented basic science. J Physiol 2012 0.76
101 Homoarginine (hArg) and asymmetric dimethylarginine (ADMA) in short stature children without and with growth hormone deficiency: hArg and ADMA are involved differently in growth in the childhood. Amino Acids 2015 0.76
102 Plasma and tissue homoarginine concentrations in healthy and obese humans. Amino Acids 2015 0.76
103 Antihypertensive inorganic nitrate and nitrite: what is the underlying mechanism? Hypertension 2013 0.76
104 Human blood platelets lack nitric oxide synthase activity. Platelets 2014 0.76
105 S-nitrosoalbumin plasma levels in health and disease: facts or artifacts? Value of analytical chemistry in nitric oxide clinical research. Circ Res 2002 0.76
106 Nitrite correlates with 3-nitrotyrosine but not with the F(2)-isoprostane 15(S)-8-iso-PGF(2alpha) in urine of rheumatic patients. Nitric Oxide 2009 0.76
107 The L-arginine/NO pathway in end-stage liver disease and during orthotopic liver and kidney transplantation: biological and analytical ramifications. Nitric Oxide 2008 0.76
108 Assessment of urinary F(2)-isoprostanes in experimental and clinical studies: mass spectrometry versus ELISA. Hypertension 2012 0.76
109 Albumin from human serum does not contain asymmetric dimethylarginine (ADMA). Clin Biochem 2009 0.76
110 Extra-platelet NO and NO(+)-containing drugs are potent inhibitors of platelet aggregation in humans by cGMP-dependent and cGMP-independent mechanisms. Blood 2012 0.76
111 Elevated plasma concentrations of the endogenous nitric oxide synthase inhibitor asymmetric dimethylarginine in citrullinemia. Metabolism 2006 0.76
112 Inorganic nitrate for blood pressure lowering? Hypertension 2010 0.75
113 Dietary eicosapentaenoic acid (EPA) to produce antileukemic cyclopentenone prostaglandin J3? Blood 2012 0.75
114 Antioxidants and endothelial dysfunction in young and elderly people: is flow-mediated dilation useful to assess acute effects? Hypertension 2012 0.75
115 Cocoa intake and blood pressure. JAMA 2007 0.75
116 Letter by Tsikas regarding article, "dietary nitrate ameliorates pulmonary hypertension: cytoprotective role for endothelial nitric oxide synthase and xanthine oxidoreductase". Circulation 2012 0.75
117 On the mercapturic acid pathway of nitric oxide: is S-nitrosoglutathione present in the bile? Hepatology 2010 0.75
118 Letter by Tsikas and Rossi regarding article, "Nitrite anion provides potent cytoprotective and antiapoptotic effects as adjunctive therapy to reperfusion for acute myocardial infarction". Circulation 2009 0.75
119 Is circulating nitrite a directly acting vasodilator? Clin Sci (Lond) 2002 0.75
120 Microdialysis of prostaglandins, thromboxane, and other eicosanoids: recall past knowledge. Hypertension 2012 0.75
121 Handling of commercially available enzyme immunoassays for 8-iso-prostaglandin F2alpha (8-iso-PGF2alpha, iPF2alpha-III, 15-F2t-IsoP) in clinical research and science: considerations from the analytical and review point of view. Clin Chim Acta 2004 0.75
122 Acute application of antioxidants protects against hyperoxia-induced reduction of plasma nitrite concentration. Clin Physiol Funct Imaging 2014 0.75
123 Measurement of nitrite in plasma and serum: still a challenging analytical task. Clin Chem Lab Med 2012 0.75
124 Are plasma S-nitrosothiol levels elevated in chronic renal failure? Nephrol Dial Transplant 2003 0.75
125 Comments on the article "Nitrosylated human serum albumin (SNO-HSA) induces apoptosis in tumor cells (Nitric Oxide 22 (2010) 259-265)". Nitric Oxide 2010 0.75
126 On the importance of the use of proper approaches for comparison of analytical methods for serum nitrate and for evaluation of reference concentrations. Clin Biochem 2009 0.75
127 Letter to the editor: "Role of the human erythrocyte in generation and storage of asymmetric dimethylarginine". Am J Physiol Heart Circ Physiol 2012 0.75
128 High urinary homoarginine excretion is associated with low rates of all-cause mortality and graft failure in renal transplant recipients. Amino Acids 2015 0.75
129 GC-MS and GC-MS/MS measurement of the cardiovascular risk factor homoarginine in biological samples. Amino Acids 2014 0.75
130 Measurement of unlabeled and stable isotope-labeled homoarginine, arginine and their metabolites in biological samples by GC-MS and GC-MS/MS. Amino Acids 2015 0.75
131 Effects of various nitric oxide donating agents on the contractility and cyclic nucleotide turnover of human seminal vesicles in vitro. Urology 2002 0.75
132 Production of prostaglandins, isoprostanes and thromboxane by Aspergillus fumigatus: identification by gas chromatography-tandem mass spectrometry and quantification by enzyme immunoassay. Mol Immunol 2011 0.75
133 Potential pitfalls with the use of acetoxy (CH(3)COO) drugs in studies on nitric oxide synthase in platelets. Nitric Oxide 2012 0.75
134 ¹⁸O-Labeled nitrous acid and nitrite: Synthesis, characterization, and oxyhemoglobin-catalyzed oxidation to ¹⁸O-labeled nitrate. Anal Biochem 2011 0.75
135 Effects of chronic oral L-arginine administration on the L-arginine/NO pathway in patients with peripheral arterial occlusive disease or coronary artery disease: L-Arginine prevents renal loss of nitrite, the major NO reservoir. Amino Acids 2015 0.75
136 Procedure-related pulmonary hypertension in patients with hepatocellular carcinoma undergoing percutaneous ethanol injection--role of ethanol, hemolysis, asymmetric dimethylarginine, and the nitric oxide system. Crit Care Med 2009 0.75
137 Serum and cerebrospinal fluid concentrations of homoarginine, arginine, asymmetric and symmetric dimethylarginine, nitrite and nitrate in patients with multiple sclerosis and neuromyelitis optica. Amino Acids 2015 0.75
138 Study of the effect of thiols on the vasodilatory potency of S-nitrosothiols by using a modified aortic ring assay. Toxicol Appl Pharmacol 2011 0.75
139 Asymmetric dimethylarginine (ADMA) is present in plasma proteins of healthy subjects at the low nmol-per-g-level. Nitric Oxide 2009 0.75
140 Sensitivity enhancement of a GC-MS/MS method for asymmetric dimethylarginine (ADMA) by plasma ultrafiltrate reduction. Anal Biochem 2007 0.75
141 Stable-isotope dilution GC-MS method for ethanol in vapour ethanol and microdialysis systems based on carbonate-catalyzed extractive pentafluorobenzoylation. Analyst 2012 0.75
142 The L-arginine/NO pathway, homoarginine, and nitrite-dependent renal carbonic anhydrase activity in young people with type 1 diabetes mellitus. Amino Acids 2015 0.75