PubRank

P Froguel

Author PubWeight™ 241.54‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity. Nat Med 2001 16.51
2 Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase. Nat Med 2002 14.15
3 Insulin-IGF2 region on chromosome 11p encodes a gene implicated in HLA-DR4-dependent diabetes susceptibility. Nature 1991 6.17
4 A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction. Nature 1998 5.75
5 A new highly penetrant form of obesity due to deletions on chromosome 16p11.2. Nature 2010 4.52
6 Genetic associations with human longevity at the APOE and ACE loci. Nat Genet 1994 4.17
7 A frameshift mutation in human MC4R is associated with a dominant form of obesity. Nat Genet 1998 4.13
8 Genomewide search for type 2 diabetes-susceptibility genes in French whites: evidence for a novel susceptibility locus for early-onset diabetes on chromosome 3q27-qter and independent replication of a type 2-diabetes locus on chromosome 1q21-q24. Am J Hum Genet 2000 3.41
9 Melanocortin-4 receptor mutations are a frequent and heterogeneous cause of morbid obesity. J Clin Invest 2000 3.00
10 Susceptibility to insulin dependent diabetes mellitus maps to a 4.1 kb segment of DNA spanning the insulin gene and associated VNTR. Nat Genet 1993 2.56
11 Variations in the HHEX gene are associated with increased risk of type 2 diabetes in the Japanese population. Diabetologia 2007 2.48
12 A genome-wide scan for human obesity genes reveals a major susceptibility locus on chromosome 10. Nat Genet 1998 2.44
13 Design and cohort description of the InterAct Project: an examination of the interaction of genetic and lifestyle factors on the incidence of type 2 diabetes in the EPIC Study. Diabetologia 2011 2.43
14 Gln-Arg192 polymorphism of paraoxonase and coronary heart disease in type 2 diabetes. Lancet 1995 2.29
15 Replication of the association between variants in WFS1 and risk of type 2 diabetes in European populations. Diabetologia 2007 2.23
16 A genome-wide scan for coronary heart disease suggests in Indo-Mauritians a susceptibility locus on chromosome 16p13 and replicates linkage with the metabolic syndrome on 3q27. Hum Mol Genet 2001 2.17
17 Chromosomal mapping of genetic loci associated with non-insulin dependent diabetes in the GK rat. Nat Genet 1996 2.09
18 Non-isotopic and sensitive method for diagnosis of maternally-inherited diabetes and deafness. Diabetologia 1994 2.03
19 The genetic abnormality in the beta cell determines the response to an oral glucose load. Diabetologia 2002 1.99
20 Primary pancreatic beta-cell secretory defect caused by mutations in glucokinase gene in kindreds of maturity onset diabetes of the young. Lancet 1992 1.95
21 Defective mutations in the insulin promoter factor-1 (IPF-1) gene in late-onset type 2 diabetes mellitus. J Clin Invest 1999 1.89
22 Genetic variation in the beta 3-adrenergic receptor and an increased capacity to gain weight in patients with morbid obesity. N Engl J Med 1995 1.88
23 Defective insulin secretion in hepatocyte nuclear factor 1alpha-deficient mice. J Clin Invest 1998 1.86
24 Mutational analysis of melanocortin-4 receptor, agouti-related protein, and alpha-melanocyte-stimulating hormone genes in severely obese children. J Pediatr 2001 1.74
25 Paraoxonase polymorphism Met-Leu54 is associated with modified serum concentrations of the enzyme. A possible link between the paraoxonase gene and increased risk of cardiovascular disease in diabetes. J Clin Invest 1997 1.71
26 The gene MAPK8IP1, encoding islet-brain-1, is a candidate for type 2 diabetes. Nat Genet 2000 1.65
27 Altered insulin secretory responses to glucose in diabetic and nondiabetic subjects with mutations in the diabetes susceptibility gene MODY3 on chromosome 12. Diabetes 1996 1.60
28 Impaired hepatic glycogen synthesis in glucokinase-deficient (MODY-2) subjects. J Clin Invest 1996 1.58
29 Maternal diabetes alters birth weight in glucokinase-deficient (MODY2) kindred but has no influence on adult weight, height, insulin secretion or insulin sensitivity. Diabetologia 2000 1.57
30 Glucokinase as pancreatic beta cell glucose sensor and diabetes gene. J Clin Invest 1993 1.55
31 Exome sequencing-driven discovery of coding polymorphisms associated with common metabolic phenotypes. Diabetologia 2012 1.55
32 A genetic variation of the transcription factor 7-like 2 gene is associated with risk of type 2 diabetes in the Japanese population. Diabetologia 2007 1.50
33 Evidence of a non-MHC susceptibility locus in type I diabetes linked to HLA on chromosome 6. Am J Hum Genet 1997 1.48
34 Missense mutations in the pancreatic islet beta cell inwardly rectifying K+ channel gene (KIR6.2/BIR): a meta-analysis suggests a role in the polygenic basis of Type II diabetes mellitus in Caucasians. Diabetologia 1998 1.46
35 Hypoadiponectinaemia and high risk of type 2 diabetes are associated with adiponectin-encoding (ACDC) gene promoter variants in morbid obesity: evidence for a role of ACDC in diabesity. Diabetologia 2005 1.44
36 A susceptibility locus for early-onset non-insulin dependent (type 2) diabetes mellitus maps to chromosome 20q, proximal to the phosphoenolpyruvate carboxykinase gene. Hum Mol Genet 1997 1.44
37 Human glucokinase gene: isolation, characterization, and identification of two missense mutations linked to early-onset non-insulin-dependent (type 2) diabetes mellitus. Proc Natl Acad Sci U S A 1992 1.40
38 Glucokinase mutations associated with non-insulin-dependent (type 2) diabetes mellitus have decreased enzymatic activity: implications for structure/function relationships. Proc Natl Acad Sci U S A 1993 1.40
39 Identification of 14 new glucokinase mutations and description of the clinical profile of 42 MODY-2 families. Diabetologia 1997 1.40
40 A large multi-centre European study validates high-sensitivity C-reactive protein (hsCRP) as a clinical biomarker for the diagnosis of diabetes subtypes. Diabetologia 2011 1.31
41 Common genetic variation near MC4R is associated with eating behaviour patterns in European populations. Int J Obes (Lond) 2009 1.30
42 HNF1alpha controls renal glucose reabsorption in mouse and man. EMBO Rep 2000 1.29
43 Cloning and characterization of the human and rat islet-specific glucose-6-phosphatase catalytic subunit-related protein (IGRP) genes. J Biol Chem 2001 1.28
44 Rapid SNP allele frequency determination in genomic DNA pools by pyrosequencing. Biotechniques 2002 1.27
45 Mutation screening of the PPARalpha gene in type 2 diabetes associated with coronary heart disease. Diabetes Metab 2000 1.26
46 The Pro115Gln and Pro12Ala PPAR gamma gene mutations in obesity and type 2 diabetes. Int J Obes Relat Metab Disord 2000 1.26
47 beta-cell genes and diabetes: quantitative and qualitative differences in the pathophysiology of hepatic nuclear factor-1alpha and glucokinase mutations. Diabetes 2001 1.25
48 Genetic susceptibility for human familial essential hypertension in a region of homology with blood pressure linkage on rat chromosome 10. Hum Mol Genet 1997 1.24
49 Mutations in the glucokinase regulatory protein gene in 2p23 in obese French caucasians. Diabetologia 2003 1.21
50 A gene for maturity onset diabetes of the young (MODY) maps to chromosome 12q. Nat Genet 1995 1.18
51 Replication of 13 obesity loci among Singaporean Chinese, Malay and Asian-Indian populations. Int J Obes (Lond) 2011 1.17
52 European genetic variants associated with type 2 diabetes in North African Arabs. Diabetes Metab 2012 1.14
53 Prevalence of macular pattern dystrophy in maternally inherited diabetes and deafness. GEDIAM Group. Ophthalmology 1999 1.14
54 Human genes involved in copy number variation: mechanisms of origin, functional effects and implications for disease. Cytogenet Genome Res 2009 1.13
55 Assessment of insulin sensitivity in glucokinase-deficient subjects. Diabetologia 1996 1.12
56 Insertion/deletion polymorphism of the angiotensin-converting enzyme gene is strongly associated with coronary heart disease in non-insulin-dependent diabetes mellitus. Proc Natl Acad Sci U S A 1994 1.11
57 Indication for linkage of the human OB gene region with extreme obesity. Diabetes 1996 1.10
58 Genetic, metabolic and clinical characteristics of maturity onset diabetes of the young. Eur J Endocrinol 1998 1.10
59 Non-sense mutation of glucokinase gene. Lancet 1993 1.09
60 Genetic studies of the sulfonylurea receptor gene locus in NIDDM and in morbid obesity among French Caucasians. Diabetes 1997 1.09
61 Anatomy of a homeoprotein revealed by the analysis of human MODY3 mutations. J Biol Chem 1999 1.07
62 Maternally inherited diabetes and deafness is a distinct subtype of diabetes and associates with a single point mutation in the mitochondrial tRNA(Leu(UUR)) gene. Diabetes 1994 1.06
63 A missense mutation in hepatocyte nuclear factor-4 alpha, resulting in a reduced transactivation activity, in human late-onset non-insulin-dependent diabetes mellitus. J Clin Invest 1998 1.06
64 Contribution of 24 obesity-associated genetic variants to insulin resistance, pancreatic beta-cell function and type 2 diabetes risk in the French population. Int J Obes (Lond) 2012 1.06
65 Identification of nine novel mutations in the hepatocyte nuclear factor 1 alpha gene associated with maturity-onset diabetes of the young (MODY3). Hum Mol Genet 1997 1.06
66 Candidate gene approach of familial morbid obesity: linkage analysis of the glucocorticoid receptor gene. Int J Obes Relat Metab Disord 1996 1.05
67 Cloning, functional expression, and chromosomal localization of the human pancreatic islet glucose-dependent insulinotropic polypeptide receptor. Diabetes 1995 1.05
68 Strong association of common variants in the CDKN2A/CDKN2B region with type 2 diabetes in French Europids. Diabetologia 2008 1.04
69 A polymorphism in the 5' untranslated region of the human ob gene is associated with low leptin levels. Int J Obes Relat Metab Disord 1998 1.04
70 No association between the G482S polymorphism of the proliferator-activated receptor-gamma coactivator-1 (PGC-1) gene and Type II diabetes in French Caucasians. Diabetologia 2002 1.04
71 Diabetes complications in NIDDM kindreds linked to the MODY3 locus on chromosome 12q. Diabetes Care 1996 1.04
72 Genetics of NIDDM in France: studies with 19 candidate genes in affected sib pairs. Diabetes 1997 1.02
73 Genetic study of the CD36 gene in a French diabetic population. Diabetes Metab 2004 1.02
74 Mutation screening in 18 Caucasian families suggest the existence of other MODY genes. Diabetologia 1998 1.01
75 GATA6 inactivating mutations are associated with heart defects and, inconsistently, with pancreatic agenesis and diabetes. Diabetologia 2012 1.00
76 Structure/function studies of human beta-cell glucokinase. Enzymatic properties of a sequence polymorphism, mutations associated with diabetes, and other site-directed mutants. J Biol Chem 1993 0.99
77 The adiponectin gene SNP+45 is associated with coronary artery disease in Type 2 (non-insulin-dependent) diabetes mellitus. Diabet Med 2004 0.98
78 A genetic variation in the 5' flanking region of the UCP3 gene is associated with body mass index in humans in interaction with physical activity. Diabetologia 2000 0.97
79 Several obesity- and nutrient-related gene polymorphisms but not FTO and UCP variants modulate postabsorptive resting energy expenditure and fat-induced thermogenesis in obese individuals: the NUGENOB study. Int J Obes (Lond) 2009 0.96
80 Additive effect of A-->G (-3826) variant of the uncoupling protein gene and the Trp64Arg mutation of the beta 3-adrenergic receptor gene on weight gain in morbid obesity. Int J Obes Relat Metab Disord 1996 0.96
81 Strategies for calibrating a subcutaneous glucose sensor. Biomed Biochim Acta 1989 0.95
82 Epistasis between type 2 diabetes susceptibility Loci on chromosomes 1q21-25 and 10q23-26 in northern Europeans. Ann Hum Genet 2006 0.95
83 Promoter polymorphism T(-107)C of the paraoxonase PON1 gene is a risk factor for coronary heart disease in type 2 diabetic patients. Diabetes 2000 0.94
84 Fine chromosome mapping of the genes for human liver and muscle carnitine palmitoyltransferase I (CPT1A and CPT1B). Genomics 1997 0.94
85 Isolation of the human LIM/homeodomain gene islet-1 and identification of a simple sequence repeat polymorphism [corrected]. Diabetes 1994 0.94
86 Differential coexpression analysis of obesity-associated networks in human subcutaneous adipose tissue. Int J Obes (Lond) 2011 0.94
87 Diagnostic heterogeneity of diabetes in lean young adults: classification based on immunological and genetic parameters. Diabetes 1997 0.94
88 Clinical phenotypes, insulin secretion, and insulin sensitivity in kindreds with maternally inherited diabetes and deafness due to mitochondrial tRNALeu(UUR) gene mutation. Diabetes 1996 0.94
89 Understanding the rising incidence of type 2 diabetes in adolescence. Arch Dis Child 2004 0.94
90 Linkage and association studies between the proopiomelanocortin (POMC) gene and obesity in caucasian families. Diabetologia 2000 0.93
91 Naturally occurring mutations in the melanocortin receptor 3 gene are not associated with type 2 diabetes mellitus in French Caucasians. J Clin Endocrinol Metab 2001 0.93
92 Polymorphism analysis of JRK/JH8, the human homologue of mouse jerky, and description of a rare mutation in a case of CAE evolving to JME. Epilepsy Res 2001 0.93
93 No major contribution of TCF7L2 sequence variants to maturity onset of diabetes of the young (MODY) or neonatal diabetes mellitus in French white subjects. Diabetologia 2006 0.92
94 Absence of an association between the polymorphisms in the genes encoding adiponectin receptors and type 2 diabetes. Diabetologia 2005 0.92
95 Multiple functional polymorphisms in the G6PC2 gene contribute to the association with higher fasting plasma glucose levels. Diabetologia 2013 0.91
96 Single nucleotide polymorphisms in the neuropeptide Y2 receptor (NPY2R) gene and association with severe obesity in French white subjects. Diabetologia 2007 0.91
97 Insulin promoter factor 1 gene is not a major cause of maturity-onset diabetes of the young in French Caucasians. Diabetes 1998 0.91
98 Soluble leptin receptor in serum of subjects with complete resistance to leptin: relation to fat mass. Diabetes 2000 0.91
99 PAI-1 polymorphisms modulate phenotypes associated with the metabolic syndrome in obese and diabetic Caucasian population. Diabetologia 2003 0.90
100 Multiple DNA variant association analysis: application to the insulin gene region in type I diabetes. Am J Hum Genet 1994 0.90
101 Association of poorly controlled diabetes with low serum leptin in morbid obesity. Int J Obes Relat Metab Disord 1997 0.90
102 Does the -11377 promoter variant of APM1 gene contribute to the genetic risk for Type 2 diabetes mellitus in Japanese families? Diabetologia 2003 0.90
103 Association of elevated lipoprotein(a) levels and coronary heart disease in NIDDM patients. Relationship with apolipoprotein(a) phenotypes. Diabetologia 1994 0.89
104 Free fatty acids and insulin levels--relationship to leptin levels and body composition in various patient groups from South Africa. Int J Obes Relat Metab Disord 1999 0.89
105 Missense mutation Gly574Ser in the transcription factor HNF-1alpha is a marker of atypical diabetes mellitus in African-American children. Diabetologia 1999 0.89
106 Transcription factor gene MNX1 is a novel cause of permanent neonatal diabetes in a consanguineous family. Diabetes Metab 2013 0.88
107 Compensation in pancreatic beta-cell function in subjects with glucokinase mutations. Diabetes 1994 0.88
108 Alcohol consumption and risk of type 2 diabetes in European men and women: influence of beverage type and body size The EPIC-InterAct study. J Intern Med 2012 0.88
109 Association between high von willebrand factor levels and the Thr789Ala vWF gene polymorphism but not with nephropathy in type I diabetes. The GENEDIAB Study Group and the DESIR Study Group. Kidney Int 2000 0.88
110 An uncoupling protein 3 gene polymorphism associated with a lower risk of developing Type II diabetes and with atherogenic lipid profile in a French cohort. Diabetologia 2000 0.87
111 Dietary fat intake and polymorphisms at the PPARG locus modulate BMI and type 2 diabetes risk in the D.E.S.I.R. prospective study. Int J Obes (Lond) 2011 0.87
112 Higher maternal than paternal inheritance of diabetes in GK rats. Diabetes 1994 0.86
113 Missense mutations in the TGM2 gene encoding transglutaminase 2 are found in patients with early-onset type 2 diabetes. Mutation in brief no. 982. Online. Hum Mutat 2007 0.86
114 B219/OB-R 5'-UTR and leptin receptor gene-related protein gene expression in mouse brain and placenta: tissue-specific leptin receptor promoter activity. J Neuroendocrinol 2000 0.86
115 ENPP1 K121Q polymorphism and obesity, hyperglycaemia and type 2 diabetes in the prospective DESIR Study. Diabetologia 2007 0.86
116 Minor contribution of SMAD7 and KLF10 variants to genetic susceptibility of type 2 diabetes. Diabetes Metab 2007 0.85
117 Indication for genetic linkage of the phosphoenolpyruvate carboxykinase (PCK1) gene region on chromosome 20q to non-insulin-dependent diabetes mellitus. Diabetes Metab 1996 0.85
118 The Gly40Ser mutation in the human glucagon receptor gene associated with NIDDM results in a receptor with reduced sensitivity to glucagon. Diabetes 1996 0.85
119 Mapping NIDDM susceptibility loci in French families: studies with markers in the region of NIDDM1 on chromosome 2q. Diabetes 1997 0.85
120 Prevalence of the missense mutation Gly574Ser in the hepatocyte nuclear factor-1alpha in Africans with diabetes. Diabetes Metab 2002 0.85
121 Polymorphism of the glycogen synthase gene and non-insulin-dependent diabetes mellitus. N Engl J Med 1993 0.85
122 Type 2 diabetes mellitus: association study of five candidate genes in an Indian population of Guadeloupe, genetic contribution of FABP2 polymorphism. Diabetes Metab 1999 0.85
123 Islet-brain1/C-Jun N-terminal kinase interacting protein-1 (IB1/JIP-1) promoter variant is associated with Alzheimer's disease. Mol Psychiatry 2003 0.84
124 Macrophage gene expression in adipose tissue is associated with insulin sensitivity and serum lipid levels independent of obesity. Obesity (Silver Spring) 2013 0.84
125 Genetic and clinical characterisation of maturity-onset diabetes of the young in Spanish families. Eur J Endocrinol 2000 0.84
126 Strategies for the collection of sibling-pair data for genetic studies in type 2 (non-insulin-dependent) diabetes mellitus. Diabetologia 1991 0.83
127 Identification of seven novel nucleotide variants in the hepatocyte nuclear factor-1alpha (TCF1) promoter region in MODY patients. Hum Mutat 2000 0.83
128 Characterization of the LIM/homeodomain gene islet-1 and single nucleotide screening in NIDDM. Diabetes 1995 0.83
129 Prevalence of mitochondrial gene mutations in families with diabetes mellitus. Lancet 1993 0.83
130 Effect of common polymorphisms in the HNF4alpha promoter on susceptibility to type 2 diabetes in the French Caucasian population. Diabetologia 2005 0.82
131 Determination of peritoneal glucose kinetics in rats: implications for the peritoneal implantation of closed-loop insulin delivery systems. Diabetologia 1989 0.82
132 GAD2: a polygenic contribution to genetic susceptibility for common obesity? Pathol Biol (Paris) 2005 0.82
133 TCF7L2 is associated with type 2 diabetes in nonobese individuals from Tunisia. Pathol Biol (Paris) 2009 0.81
134 Lipoprotein(a) in diabetic patients and normoglycemic relatives in familial NIDDM. Diabetes Care 1993 0.81
135 Evaluating the association of common LMNA variants with type 2 diabetes and quantitative metabolic phenotypes in French Europids. Diabetologia 2007 0.81
136 A sib-pair analysis study of 15 candidate genes in French families with morbid obesity: indication for linkage with islet 1 locus on chromosome 5q. Diabetes 1999 0.81
137 Insulin receptor substrate (IRS-1) gene polymorphisms in French NIDDM families. Lancet 1993 0.81
138 Are animal models of diabetes relevant to the study of the genetics of non-insulin-dependent diabetes in humans? Diabetes Metab 1997 0.81
139 No association between the Friedreich's ataxia gene and NIDDM in the French population. Diabetes 1998 0.81
140 Routine mutation screening of HNF-1alpha and GCK genes in MODY diagnosis: how effective are the techniques of DHPLC and direct sequencing used in combination? Diabetologia 2001 0.81
141 Genetic determinants of non-insulin-dependent diabetes mellitus: strategies and recent results. Diabetes Metab 1997 0.81
142 Mutation screening of the human UCP 2 gene in normoglycemic and NIDDM morbidly obese patients: lack of association between new UCP 2 polymorphisms and obesity in French Caucasians. Diabetes 1998 0.81
143 Effect of ENPP1/PC-1-K121Q and PPARgamma-Pro12Ala polymorphisms on the genetic susceptibility to T2D in the Tunisian population. Diabetes Res Clin Pract 2008 0.80
144 The EIF2AK3 gene region and type I diabetes in subjects from South India. Genes Immun 2004 0.80
145 Glucokinase gene mutations are not a common cause of permanent neonatal diabetes in France. Diabetologia 2002 0.80
146 Leptin receptor gene in a large cohort of massively obese subjects: no indication of the fa/fa rat mutation. Detection of an intronic variant with no association with obesity. Obes Res 1998 0.79
147 Genetics of human obesity. Best Pract Res Clin Endocrinol Metab 2001 0.79
148 No evidence of linkage or diabetes-associated mutations in the transcription factors BETA2/NEUROD1 and PAX4 in Type II diabetes in France. Diabetologia 1999 0.79
149 Linkage analyses of the MODY3 locus on chromosome 12q with late-onset NIDDM. Diabetes 1995 0.79
150 The genetics of non-insulin-dependent diabetes mellitus: tools and aims. Diabetologia 1994 0.79
151 Allelic variation in exon 18 of the sulfonylurea receptor 1 (SUR1) gene, insulin secretion and insulin sensitivity in nondiabetic relatives of type 2 diabetic subjects. Diabetes Metab 2002 0.79
152 Maturity-onset diabetes of the young (MODY), MODY genes and non-insulin-dependent diabetes mellitus. Diabetes Metab 1997 0.79
153 Genetic studies of the leptin receptor gene in morbidly obese French Caucasian families. Hum Genet 1997 0.79
154 Mutation screening and association studies of the human uncoupling protein 3 gene in normoglycemic and diabetic morbidly obese patients. Diabetes 1999 0.79
155 Phenotyping is an accurate means of analysing the principal apolipoprotein E isoforms. Clin Chim Acta 1994 0.78
156 Genetic variation in the hepatocyte nuclear factor-3beta gene (HNF3B) does not contribute to maturity-onset diabetes of the young in French Caucasians. Diabetes 2000 0.78
157 Amino acid exchange between plasma and erythrocytes in vivo in humans. J Appl Physiol (1985) 1989 0.78
158 Automated fluorescence-based screening for mutation by SSCP: use of universal M13 dye primers for labeling and detection. Biotechniques 1997 0.78
159 [Neonatal diabetes: a disease linked to multiple mechanisms]. Arch Pediatr 2007 0.78
160 Absence of replication in the French population of the association between beta 2/NEUROD-A45T polymorphism and type 1 diabetes. Diabetes Metab 1999 0.77
161 Molecular and cytogenetic characterisation of a small interstitial de novo 20p13-->p12.3 deletion in a patient with severe growth deficit. Cytogenet Cell Genet 2001 0.77
162 Genetic studies of polymorphisms in ten non-insulin-dependent diabetes mellitus candidate genes in Tamil Indians from Pondichery. Diabetes Metab 1998 0.77
163 Association of the ENPP1 K121Q polymorphism with type 2 diabetes and obesity in the Moroccan population. Diabetes Metab 2008 0.77
164 Big Dye terminator cycle sequencing chemistry: accuracy of the dilution process and application for screening mutations in the TCF1 and GCK genes. Hum Mutat 2000 0.77
165 Genetic studies of neuropeptide Y and neuropeptide Y receptors Y1 and Y5 regions in morbid obesity. Diabetologia 1997 0.76
166 Study and development of multilayer needle-type enzyme-based glucose microsensors. Biosensors 1989 0.76
167 Genetic and environmental nature of the insulin resistance syndrome in Indo-Mauritian subjects with premature coronary heart disease: contribution of beta3-adrenoreceptor gene polymorphism and beta blockers on triglyceride and HDL concentrations. Diabetologia 2001 0.76
168 Dissection of an inverted X(p21.3q27.1) chromosome associated with mental retardation. Cytogenet Genome Res 2003 0.76
169 A genetic study of the ghrelin and growth hormone secretagogue receptor (GHSR) genes and stature. Ann Hum Genet 2008 0.76
170 Reassessment of the putative role of BLK-p.A71T loss-of-function mutation in MODY and type 2 diabetes. Diabetologia 2012 0.76
171 Mutation screening of the urocortin gene: identification of new single nucleotide polymorphisms and association studies with obesity in French Caucasians. J Clin Endocrinol Metab 2002 0.76
172 Gender effect of the Trp64Arg mutation in the beta 3 adrenergic receptor gene on weight gain in morbid obesity. Diabetes Metab 1997 0.76
173 Genetic studies of the renin-angiotensin system in arterial hypertension associated with non-insulin-dependent diabetes mellitus. J Hypertens 1997 0.75
174 Beta 3-adrenoceptor gene variant in obesity and insulin resistance. Lancet 1996 0.75
175 No evidence for diabetes-associated mutations of PEK/EIF2AK3 gene in French patients with early-onset type II diabetes. Diabetologia 2001 0.75
176 Mutations in G6PC2 do not contribute to monogenic forms of early infancy diabetes and beta cell dysfunction. Diabetologia 2009 0.75
177 Glucose utilization and production in patients with maturity-onset diabetes of the young caused by a mutation of the hepatocyte nuclear factor-1alpha gene. Diabetes 1998 0.75
178 The (Ala-Val) mutation of methylenetetrahydrofolate reductase as a genetic risk factor for vascular disease in non-insulin-dependent diabetic patients. Am J Hum Genet 1997 0.75
179 An automated fluorescent single-strand conformation polymorphism technique for screening mutations in the hepatocyte nuclear factor-1alpha gene (maturity-onset diabetes of the young). Diabetes 1997 0.75
180 Mutations of the human glucokinase gene and diabetes mellitus. Trends Endocrinol Metab 1993 0.75
181 No evidence for linkage or for diabetes-associated mutations in the activin type 2B receptor gene (ACVR2B) in French patients with mature-onset diabetes of the young or type 2 diabetes. Diabetes 2001 0.75
182 [Genetic risk of non-insulin-dependent diabetes]. Journ Annu Diabetol Hotel Dieu 1998 0.75
183 Genetic analyses of glucose transporter genes in French non-insulin-dependent diabetic families. Diabetes Metab 1997 0.75
184 Nonradioactive screening of glucokinase mutations in maturity onset diabetes of the young. Biotechniques 1994 0.75
185 Rare variants identified in the HNF- 4 alpha beta-cell-specific promoter and alternative exon 1 lack biological significance in maturity onset diabetes of the young and young onset Type II diabetes. Diabetologia 2002 0.75
186 Two Caucasian families with the hepatocyte nuclear factor-1alpha mutation Tyr218Cys. Exp Clin Endocrinol Diabetes 2007 0.75
187 [Genetics of non-insulin-dependent diabetes mellitus: the end of the nightmare?]. Pathol Biol (Paris) 1992 0.75
188 D-glucose metabolism in lymphocytes of patients with mitochondrial point mutation of the tRNALeu(UUR) gene. Biochem Mol Med 1995 0.75
189 Insulin secretion and insulin sensitivity in diabetic and non-diabetic subjects with hepatic nuclear factor-1alpha (maturity-onset diabetes of the young-3) mutations. Eur J Endocrinol 1999 0.75
190 [What have we learned thanks to genetics in type II diabetes and its complications?]. Nephrologie 1999 0.75
191 Identification of trinucleotide repeat-containing genes in human pancreatic islets. Diabetes 1996 0.75
192 Arginine-induced insulin release in glucokinase-deficient subjects. Diabetes Care 1994 0.75
193 In vitro and in vivo stability of electrode potentials in needle-type glucose sensors. Influence of needle material. Diabetes 1989 0.75
194 [Leptin and genetics of obesity]. Journ Annu Diabetol Hotel Dieu 1997 0.75