Published in Genetics on November 01, 1943
Replica plating and indirect selection of bacterial mutants. J Bacteriol (1952) 59.66
Bacteriophage-Resistant Mutants in Escherichia Coli. Genetics (1945) 42.51
Gene Recombination in the Bacterium Escherichia coli. J Bacteriol (1947) 29.68
Biochemical Mutants in the Smut Fungus Ustilago Maydis. Genetics (1949) 25.91
Production of Staphylococcus Strains Resistant to Various Concentrations of Penicillin. Proc Natl Acad Sci U S A (1945) 23.57
The Inheritance of Requirements for Adsorption Cofactors in the Bacterial Virus T4. J Bacteriol (1948) 21.33
Mutation of Bacteriophage with Respect to Type of Plaque. Genetics (1946) 19.73
RECENT ADVANCES IN BACTERIAL GENETICS. Bacteriol Rev (1947) 18.75
Induced Mutations and Possible Mechanisms of the Transmission of Heredity in Escherichia Coli. Proc Natl Acad Sci U S A (1946) 16.36
Delayed Phenotypic Expression of Spontaneous Mutations in Escherichia Coli. Genetics (1948) 15.65
BACTERIAL DISSOCIATION: A Critical Review of a Phenomenon of Bacterial Variation. Bacteriol Rev (1947) 14.61
Genetics of Resistance to Radiation in ESCHERICHIA COLI. Genetics (1947) 14.20
Origin of Bacterial Resistance to Antibiotics. J Bacteriol (1948) 13.01
Bacteriophage typing of enteric pathogens and staphylococci and its use in epidemiology. J Clin Pathol (1956) 12.73
Incidence of Metabolic Changes among Virus-Resistant Mutants of a Bacterial Strain. Proc Natl Acad Sci U S A (1944) 12.71
Lysis and Lysis Inhibition with Escherichia coli Bacteriophage. J Bacteriol (1948) 12.06
A constant rate of spontaneous mutation in DNA-based microbes. Proc Natl Acad Sci U S A (1991) 11.66
Inherited Differences in Sensitivity to Radiation in Escherichia Coli. Proc Natl Acad Sci U S A (1946) 11.62
Mutations during the Growth of Biochemical Mutants of Escherichia Coli. Genetics (1949) 11.38
The molecular evolution of acquired resistance to targeted EGFR blockade in colorectal cancers. Nature (2012) 10.17
Host controlled variation in bacterial viruses. J Bacteriol (1953) 9.46
Cancer as an evolutionary and ecological process. Nat Rev Cancer (2006) 9.33
Studies on the nutrition and physiology of Pasteurella pestis. VI. A differential plating medium for the estimation of the mutation rate to avirulence. J Bacteriol (1961) 9.14
Multiple trait analysis of genetic mapping for quantitative trait loci. Genetics (1995) 8.84
Experiments to Test the Validity of the Linear R-Dose/Mutation Frequency Relation in Drosophila at Low Dosage. Genetics (1948) 8.43
Reversal of mutant phenotypes by 5-fluorouracil: an approach to nucleotide sequences in messenger-RNA. Proc Natl Acad Sci U S A (1962) 8.33
SPONTANEOUS MUTATION TO STREPTOMYCIN RESISTANCE AND DEPENDENCE IN ESCHERICHIA COLI. J Bacteriol (1949) 7.70
CHROMOSOMAL ABERRATIONS ASSOCIATED WITH MUTATIONS TO BACTERIOPHAGE RESISTANCE IN ESCHERICHIA COLI. J Bacteriol (1965) 7.61
Transduction in Escherichia Coli K-12. Genetics (1956) 7.54
Amplifiable resistance to tetracycline, chloramphenicol, and other antibiotics in Escherichia coli: involvement of a non-plasmid-determined efflux of tetracycline. J Bacteriol (1983) 7.06
On the cytoplasmic nature of "long-term adaptation" in yeast. Proc Natl Acad Sci U S A (1950) 6.84
Detection of numerous Y chromosome biallelic polymorphisms by denaturing high-performance liquid chromatography. Genome Res (1997) 6.73
Dissociation in Brucella abortus: A Demonstration of the Rôle of Inherent and Environmental Factors in Bacterial Variation. J Bacteriol (1946) 6.51
Mutation rates among RNA viruses. Proc Natl Acad Sci U S A (1999) 6.37
Functional genomics: expression analysis of Escherichia coli growing on minimal and rich media. J Bacteriol (1999) 6.10
Mutations to Sulfonamide Resistance in STAPHYLOCOCCUS AUREUS. Genetics (1947) 6.05
Organization of the bacterial chromosome. Microbiol Rev (1990) 6.01
Adaptive reversion of a frameshift mutation in Escherichia coli. Genetics (1991) 5.92
On the Stability of Nutritional Mutants of Bacteria. Proc Natl Acad Sci U S A (1948) 5.87
Mutations Involving the Requirement of Uracil in Clostridium. Proc Natl Acad Sci U S A (1946) 5.81
Mutations affecting Ty-mediated expression of the HIS4 gene of Saccharomyces cerevisiae. Genetics (1984) 5.64
Molecular mechanism of regulation of siderophore-mediated iron assimilation. Microbiol Rev (1987) 5.56
Rates of spontaneous mutation among RNA viruses. Proc Natl Acad Sci U S A (1993) 5.42
A Factor (or Mutator Gene) Influencing Mutation Rates in Escherichia Coli. Proc Natl Acad Sci U S A (1954) 5.36
Historical contingency and the evolution of a key innovation in an experimental population of Escherichia coli. Proc Natl Acad Sci U S A (2008) 5.29
YEAST GENETICS : Life Cycles, Cytology, Hybridization, Vitamin Synthesis, and Adaptive Enzymes. Bacteriol Rev (1945) 5.15
Compensatory mutations, antibiotic resistance and the population genetics of adaptive evolution in bacteria. Genetics (2000) 4.98
Flagellar mutants of Chlamydomonas: studies of radial spoke-defective strains by dikaryon and revertant analysis. Proc Natl Acad Sci U S A (1977) 4.91
Specific substitutions in the echinocandin target Fks1p account for reduced susceptibility of rare laboratory and clinical Candida sp. isolates. Antimicrob Agents Chemother (2005) 4.89
AACR centennial series: the biology of cancer metastasis: historical perspective. Cancer Res (2010) 4.89
Spontaneous point mutations that occur more often when advantageous than when neutral. Genetics (1990) 4.89
Different Rates of Spontaneous Mutation during Mitosis and Meiosis in Yeast. Genetics (1962) 4.71
Antigenic modulation of Bordetella pertussis. J Hyg (Lond) (1960) 4.61
Conditional-lethal mutations that suppress genetic defects in morphogenesis by altering structural proteins. Proc Natl Acad Sci U S A (1975) 4.52
A pre-Columbian Y chromosome-specific transition and its implications for human evolutionary history. Proc Natl Acad Sci U S A (1996) 4.52
Studies on the variation of Bacterium tularense. J Bacteriol (1951) 4.46
Instability of simple sequence DNA in Saccharomyces cerevisiae. Mol Cell Biol (1992) 4.46
Transposition derivatives of an Hfr strain of Escherichia coli K-12. Genetics (1967) 4.39
Disease gene mapping in isolated human populations: the example of Finland. J Med Genet (1993) 4.25
Determining mutation rates in bacterial populations. Methods (2000) 4.15
Clonal evolution in breast cancer revealed by single nucleus genome sequencing. Nature (2014) 4.13
Direction of chromosome rearrangements in Saccharomyces cerevisiae by use of his3 recombinational substrates. Mol Cell Biol (1988) 4.06
The genetic control of direct-repeat recombination in Saccharomyces: the effect of rad52 and rad1 on mitotic recombination at GAL10, a transcriptionally regulated gene. Genetics (1989) 4.00
Challenges of antibacterial discovery. Clin Microbiol Rev (2011) 3.94
Viral mutation rates. J Virol (2010) 3.87
Mechanisms causing rapid and parallel losses of ribose catabolism in evolving populations of Escherichia coli B. J Bacteriol (2001) 3.84
Rate of somatic mutation in immunoglobulin production by mouse myeloma cells. Proc Natl Acad Sci U S A (1971) 3.83
Growth control in cultured cells: selection of sublines with increased sensitivity to contact inhibition and decreased tumor-producing ability. Proc Natl Acad Sci U S A (1968) 3.78
Oxygen-dependent mutagenesis in Escherichia coli lacking superoxide dismutase. Proc Natl Acad Sci U S A (1986) 3.73
Meiotic gene conversion mutants in Saccharomyces cerevisiae. I. Isolation and characterization of pms1-1 and pms1-2. Genetics (1985) 3.71
Marker discrimination in transformation and mutation of pneumococcus. Proc Natl Acad Sci U S A (1973) 3.68
Mutation as a stress response and the regulation of evolvability. Crit Rev Biochem Mol Biol (2007) 3.66
Probability distribution of drug-resistant mutants in unselected populations of Mycobacterium tuberculosis. Appl Microbiol (1970) 3.65
Homologous recombination in mammalian cells mediates formation of a functional gene from two overlapping gene fragments. Proc Natl Acad Sci U S A (1983) 3.60
The repertoire and dynamics of evolutionary adaptations to controlled nutrient-limited environments in yeast. PLoS Genet (2008) 3.58
Mutator phenotype of Werner syndrome is characterized by extensive deletions. Proc Natl Acad Sci U S A (1989) 3.55
The potential for respiratory droplet-transmissible A/H5N1 influenza virus to evolve in a mammalian host. Science (2012) 3.50
Cloning and sequencing of the alcohol dehydrogenase II gene from Zymomonas mobilis. J Bacteriol (1987) 3.49
Benzoate metabolism in Pseudomonas putida(arvilla) mt-2: demonstration of two benzoate pathways. J Bacteriol (1973) 3.41
Two Streptomycin-resistant Variants of Meningococcus. J Bacteriol (1947) 3.36
Linkage disequilibrium mapping in isolated populations: the example of Finland revisited. Proc Natl Acad Sci U S A (1998) 3.35
Antibody-resistant mutants of Borrelia burgdorferi: in vitro selection and characterization. J Exp Med (1992) 3.30
Opaque-white phenotype transition: a programmed morphological transition in Candida albicans. J Bacteriol (1988) 3.29
Mutation frequencies and antibiotic resistance. Antimicrob Agents Chemother (2000) 3.27
Estimating the per-base-pair mutation rate in the yeast Saccharomyces cerevisiae. Genetics (2008) 3.18
Frameshifting is required for production of the transposase encoded by insertion sequence 1. Proc Natl Acad Sci U S A (1989) 3.18
Adaptive mutation: the uses of adversity. Annu Rev Microbiol (1993) 3.17
Adaptation of membrane lipids to alcohols. J Bacteriol (1976) 3.14
Bloom's and Werner's syndrome genes suppress hyperrecombination in yeast sgs1 mutant: implication for genomic instability in human diseases. Proc Natl Acad Sci U S A (1998) 3.14
Saccharomyces cerevisiae RAD5-encoded DNA repair protein contains DNA helicase and zinc-binding sequence motifs and affects the stability of simple repetitive sequences in the genome. Mol Cell Biol (1992) 3.12
Genome-wide hypermutation in a subpopulation of stationary-phase cells underlies recombination-dependent adaptive mutation. EMBO J (1997) 3.09
Genetic engineering of ethanol production in Escherichia coli. Appl Environ Microbiol (1987) 3.06
Characterization of a mutant strain of Saccharomyces cerevisiae with a deletion of the RAD27 gene, a structural homolog of the RAD2 nucleotide excision repair gene. J Bacteriol (1995) 3.05
Fluctuation analysis CalculatOR: a web tool for the determination of mutation rate using Luria-Delbruck fluctuation analysis. Bioinformatics (2009) 3.05
Adaptive evolution that requires multiple spontaneous mutations. I. Mutations involving an insertion sequence. Genetics (1988) 3.05
Transmission of single HIV-1 genomes and dynamics of early immune escape revealed by ultra-deep sequencing. PLoS One (2010) 3.02
Mutation rate and evolution of fluoroquinolone resistance in Escherichia coli isolates from patients with urinary tract infections. Antimicrob Agents Chemother (2003) 3.00
Mutation and selection in bacterial populations: alternatives to the hypothesis of directed mutation. Proc Natl Acad Sci U S A (1989) 2.95
Factors Responsible for the Delayed Appearance of Radiation-Induced Mutants in Escherichia Coli. Genetics (1949) 2.94
Synergism of Xist RNA, DNA methylation, and histone hypoacetylation in maintaining X chromosome inactivation. J Cell Biol (2001) 2.94
A Description of Some Color Variants Produced by Serratia marcescens, Strain 274. J Bacteriol (1940) 108.31
The Distribution of Color Variants in Ageing Broth Cultures of Serratia Marcescens #274. J Bacteriol (1942) 71.99
Electron Microscope Studies of Bacterial Viruses. J Bacteriol (1943) 32.99
Mutations of Bacterial Viruses Affecting Their Host Range. Genetics (1945) 26.70
Brownian motion in biological membranes. Proc Natl Acad Sci U S A (1975) 13.76
The Mechanism of Genetic Recombination in Phage. Genetics (1953) 12.36
Phycomyces. Bacteriol Rev (1969) 9.15
THE GROWTH OF BACTERIOPHAGE. J Gen Physiol (1939) 2.99
Signal transducers: terra incognita of molecular biology. Angew Chem Int Ed Engl (1972) 2.11
THE NATURE OF THE INTERMOLECULAR FORCES OPERATIVE IN BIOLOGICAL PROCESSES. Science (1940) 1.89
Avoidance response, house response, and wind responses of the sporangiophore of Phycomyces. J Gen Physiol (1975) 1.65
Absorption and screening in Phycomyces. J Gen Physiol (1967) 1.50
Complementation between mutants of Phycomyces deficient with respect to carotenogenesis. Mol Gen Genet (1973) 1.50
Responses of Phycomyces indicating optical excitation of the lowest triplet state of riboflavin. Proc Natl Acad Sci U S A (1976) 1.49
Replacement of riboflavin by an analogue in the blue-light photoreceptor of Phycomyces. Proc Natl Acad Sci U S A (1981) 1.19
Genetic recombination in sexual crosses of phycomyces. Genetics (1975) 1.15
Effects of cold periods on the stimulus-response system of Phycomyces. J Gen Physiol (1970) 1.03
Meiosis in Phycomyces. Proc Natl Acad Sci U S A (1975) 1.02
A physicist's renewed look at biology: twenty years later. Science (1970) 0.87
Scientific ties and human rights. Science (1979) 0.75