Monocyte-macrophage system as a target for estrogen and selective estrogen receptor modulators.

PubWeight™: 1.06‹?› | Rank: Top 15%

🔗 View Article (PMID 17261769)

Published in Ann N Y Acad Sci on November 01, 2006

Authors

Pirkko L Härkönen1, H Kalervo Väänänen

Author Affiliations

1: Lund University, Department of Laboratory Medicine, Tumor Biology, Malmö University Hospital, CRC Entrance 72, 205 02 Malmö, Sweden. pirkko.harkonen@med.lu.se

Articles citing this

Sex steroid hormones, hormonal contraception, and the immunobiology of human immunodeficiency virus-1 infection. Endocr Rev (2009) 1.95

27-hydroxycholesterol is an endogenous selective estrogen receptor modulator. Mol Endocrinol (2007) 1.75

Breast tumour angiogenesis. Breast Cancer Res (2007) 1.22

Inferring novel disease indications for known drugs by semantically linking drug action and disease mechanism relationships. BMC Bioinformatics (2009) 1.12

Regulation of dendritic cell differentiation and function by estrogen receptor ligands. Cell Immunol (2008) 1.05

Hydroxychloroquine inhibits autophagy to potentiate antiestrogen responsiveness in ER+ breast cancer. Clin Cancer Res (2014) 0.95

Estrogen receptor-alpha promotes alternative macrophage activation during cutaneous repair. J Invest Dermatol (2014) 0.92

Differential functional genomic effects of anti-inflammatory phytocompounds on immune signaling. BMC Genomics (2010) 0.91

Obesity-driven inflammation and cancer risk: role of myeloid derived suppressor cells and alternately activated macrophages. Am J Cancer Res (2013) 0.89

Paracrine interactions between primary human macrophages and human fibroblasts enhance murine mammary gland humanization in vivo. Breast Cancer Res (2012) 0.89

Steroid hormone signaling is essential to regulate innate immune cells and fight bacterial infection in Drosophila. PLoS Pathog (2013) 0.88

Immune cell location and function during post-natal mammary gland development. J Mammary Gland Biol Neoplasia (2010) 0.88

Estriol generates tolerogenic dendritic cells in vivo that protect against autoimmunity. J Immunol (2011) 0.86

Estrogen signaling in metabolic inflammation. Mediators Inflamm (2014) 0.85

In human invasive breast ductal carcinoma, tumor stromal macrophages and tumor nest macrophages have distinct relationships with clinicopathological parameters and tumor angiogenesis. Virchows Arch (2013) 0.84

Sex and gender in psychoneuroimmunology research: past, present and future. Brain Behav Immun (2009) 0.84

17β-estradiol protects primary macrophages against HIV infection through induction of interferon-alpha. Viral Immunol (2014) 0.82

Monocyte-Induced Prostate Cancer Cell Invasion is Mediated by Chemokine ligand 2 and Nuclear Factor-κB Activity. J Clin Cell Immunol (2015) 0.80

Progesterone protects normative anxiety-like responding among ovariectomized female mice that conditionally express the HIV-1 regulatory protein, Tat, in the CNS. Horm Behav (2014) 0.79

Estrogen receptors alpha and beta in bone. Bone (2016) 0.78

Endobiogeny: a global approach to systems biology (part 2 of 2). Glob Adv Health Med (2013) 0.78

Novel innate cancer killing activity in humans. Cancer Cell Int (2011) 0.78

The pulmonary inflammatory response to multiwalled carbon nanotubes is influenced by gender and glutathione synthesis. Redox Biol (2016) 0.77

Extra-gonadal sites of estrogen biosynthesis and function. BMB Rep (2016) 0.77

Estrogen-induced nongenomic calcium signaling inhibits lipopolysaccharide-stimulated tumor necrosis factor α production in macrophages. PLoS One (2013) 0.77

Gender difference in gastro-esophageal reflux diseases. World J Gastroenterol (2016) 0.76

FNDC4 acts as an anti-inflammatory factor on macrophages and improves colitis in mice. Nat Commun (2016) 0.75

Articles by these authors

Serum osteocalcin is not associated with glucose but is inversely associated with leptin across generations of nondiabetic women. J Clin Endocrinol Metab (2012) 1.49

Alendronate inhibits invasion of PC-3 prostate cancer cells by affecting the mevalonate pathway. Cancer Res (2002) 1.46

Further insight into mechanism of action of clodronate: inhibition of mitochondrial ADP/ATP translocase by a nonhydrolyzable, adenine-containing metabolite. Mol Pharmacol (2002) 1.38

Isolated primary osteocytes express functional gap junctions in vitro. Cell Tissue Res (2005) 1.36

Conditioned medium from osteocytes stimulates the proliferation of bone marrow mesenchymal stem cells and their differentiation into osteoblasts. Exp Cell Res (2004) 1.28

Tartrate-resistant acid phosphatase 5b (TRACP 5b) as a marker of bone resorption. Clin Lab (2006) 1.22

Osteocytes inhibit osteoclastic bone resorption through transforming growth factor-beta: enhancement by estrogen. J Cell Biochem (2002) 1.22

Osteoclast-derived serum tartrate-resistant acid phosphatase 5b in Albers-Schonberg disease (type II autosomal dominant osteopetrosis). Clin Chem (2004) 1.17

Biochemical markers of bone metabolism and prediction of fracture in elderly women. J Bone Miner Res (2003) 1.16

Intracellular machinery for matrix degradation in bone-resorbing osteoclasts. J Bone Miner Res (2004) 1.15

Osteoclast ruffled border has distinct subdomains for secretion and degraded matrix uptake. Traffic (2003) 1.14

The critical role of IL-34 in osteoclastogenesis. PLoS One (2011) 1.14

FGF-8 is involved in bone metastasis of prostate cancer. Int J Cancer (2008) 1.13

Intracellular membrane trafficking in bone resorbing osteoclasts. Microsc Res Tech (2003) 1.13

Estrogen and testosterone use different cellular pathways to inhibit osteoclastogenesis and bone resorption. J Bone Miner Res (2005) 1.12

Associations between homocysteine, bone turnover, BMD, mortality, and fracture risk in elderly women. J Bone Miner Res (2007) 1.11

Release of intact and fragmented osteocalcin molecules from bone matrix during bone resorption in vitro. J Biol Chem (2004) 1.11

Death of osteocytes turns off the inhibition of osteoclasts and triggers local bone resorption. Biochem Biophys Res Commun (2005) 1.11

Possible role of direct Rac1-Rab7 interaction in ruffled border formation of osteoclasts. J Biol Chem (2005) 1.01

Bone turnover markers and prediction of fracture: a prospective follow-up study of 1040 elderly women for a mean of 9 years. J Bone Miner Res (2010) 0.99

Breast cancer cells with inhibition of p38alpha have decreased MMP-9 activity and exhibit decreased bone metastasis in mice. Clin Exp Metastasis (2004) 0.98

Membrane-bound carbonic anhydrases in osteoclasts. Bone (2006) 0.98

Bone marrow cell differentiation induced by mechanically damaged osteocytes in 3D gel-embedded culture. J Bone Miner Res (2006) 0.97

Human mesenchymal stem cell derived osteoblasts degrade organic bone matrix in vitro by matrix metalloproteinases. Matrix Biol (2005) 0.96

Serial assessment of serum bone metabolism markers identifies women with the highest rate of bone loss and osteoporosis risk. J Clin Endocrinol Metab (2008) 0.95

Biochemical markers of bone turnover are influenced by recently sustained fracture. Bone (2005) 0.93

Serum TRACP 5b is a useful marker for monitoring alendronate treatment: comparison with other markers of bone turnover. J Bone Miner Res (2005) 0.93

Regulation of osteoblast differentiation: a novel function for fibroblast growth factor 8. Endocrinology (2006) 0.92

Intracellular membrane trafficking pathways in bone-resorbing osteoclasts revealed by cloning and subcellular localization studies of small GTP-binding rab proteins. Biochem Biophys Res Commun (2002) 0.92

Estrogen responsiveness of bone formation in vitro and altered bone phenotype in aged estrogen receptor-alpha-deficient male and female mice. Eur J Endocrinol (2005) 0.91

Transient 100 nM dexamethasone treatment reduces inter- and intraindividual variations in osteoblastic differentiation of bone marrow-derived human mesenchymal stem cells. Tissue Eng Part C Methods (2012) 0.91

Receptor tyrosine kinase inhibition causes simultaneous bone loss and excess bone formation within growing bone in rats. Toxicol Appl Pharmacol (2011) 0.91

Evidence for the role of osteocytes in the initiation of targeted remodeling. Technol Health Care (2009) 0.91

RNA interference tolerates 2'-fluoro modifications at the Argonaute2 cleavage site. Chem Biodivers (2007) 0.89

Overexpression of vascular endothelial growth factor C increases growth and alters the metastatic pattern of orthotopic PC-3 prostate tumors. BMC Cancer (2009) 0.89

The effects of tamoxifen and toremifene on bone cells involve changes in plasma membrane ion conductance. J Bone Miner Res (2003) 0.88

Phosphatase and oxygen radical-generating activities of mammalian purple acid phosphatase are functionally independent. Biochem Biophys Res Commun (2002) 0.88

Estrogen and the selective estrogen receptor modulator (SERM) protection against cell death in estrogen receptor alpha and beta expressing U2OS cells. Mol Cell Endocrinol (2008) 0.88

Inhibition of the osteoclast V-ATPase by small interfering RNAs. FEBS Lett (2005) 0.88

Urinary osteocalcin as a marker of bone metabolism. Clin Chem (2005) 0.88

Potential function for the ROS-generating activity of TRACP. J Bone Miner Res (2003) 0.87

Macrophages overexpressing tartrate-resistant acid phosphatase show altered profile of free radical production and enhanced capacity of bacterial killing. Biochem Biophys Res Commun (2005) 0.86

Overexpression of cathepsin K accelerates the resorption cycle and osteoblast differentiation in vitro. Bone (2008) 0.86

Cystatin B as an intracellular modulator of bone resorption. Matrix Biol (2006) 0.86

Degradation of hydroxyapatite in vivo and in vitro requires osteoclastic sodium-bicarbonate co-transporter NBCn1. Matrix Biol (2010) 0.86

A rationale for osteoclast selectivity of inhibiting the lysosomal V-ATPase a3 isoform. Calcif Tissue Int (2010) 0.86

FGF-8b induces growth and rich vascularization in an orthotopic PC-3 model of prostate cancer. J Cell Biochem (2009) 0.86

Pharmacological sequestration of intracellular cholesterol in late endosomes disrupts ruffled border formation in osteoclasts. J Bone Miner Res (2005) 0.86

The architecture of microtubular network and Golgi orientation in osteoclasts--major differences between avian and mammalian species. Exp Cell Res (2003) 0.84

Bisphosphonate induced growth inhibition of breast cancer cells is augmented by p38 inhibition. Breast Cancer Res Treat (2003) 0.83

Improved methods for testing antiresorptive compounds in human osteoclast cultures. J Bone Miner Metab (2008) 0.82

Tumor necrosis factor-alpha induces interleukin-6 production via extracellular-regulated kinase 1 activation in breast cancer cells. Breast Cancer Res Treat (2003) 0.81

Rab13 is upregulated during osteoclast differentiation and associates with small vesicles revealing polarized distribution in resorbing cells. J Histochem Cytochem (2012) 0.81

Sequence and TLR9 independent increase of TRACP expression by antisense DNA and siRNA molecules. Biochem Biophys Res Commun (2007) 0.81

Recombinant VSV G proteins reveal a novel raft-dependent endocytic pathway in resorbing osteoclasts. Exp Cell Res (2008) 0.80

Effects of proteolysis and reduction on phosphatase and ROS-generating activity of human tartrate-resistant acid phosphatase. Arch Biochem Biophys (2006) 0.79

Novel perspectives on the transcytotic route in osteoclasts. Bonekey Rep (2013) 0.78

Analysis by siRNA_profile program displays novel thermodynamic characteristics of highly functional siRNA molecules. Source Code Biol Med (2008) 0.78

Tartrate-resistant acid phosphatase 5B circulates in human serum in complex with alpha2-macroglobulin and calcium. Biochem Biophys Res Commun (2003) 0.78

Identification of novel proteolytic forms of osteocalcin in human urine. Biochem Biophys Res Commun (2003) 0.77

Skeletal changes in transgenic male mice expressing human cytochrome p450 aromatase. J Bone Miner Res (2004) 0.76

Urinary osteocalcin and serum pro-C-type natriuretic peptide predict linear catch-up growth in infants. J Bone Miner Res (2012) 0.76

Overexpression of human hydroxysteroid (17beta) dehydrogenase 2 induces disturbance in skeletal development in young male mice. J Bone Miner Res (2008) 0.76

Urinary osteocalcin is a useful marker for monitoring the effect of alendronate therapy. Clin Chem (2005) 0.75

Clinical performance of six different serum tartrate-resistant acid phosphatase assays for monitoring alendronate treatment. Clin Lab (2008) 0.75