Published in Leukemia on February 01, 2007
Recurring mutations found by sequencing an acute myeloid leukemia genome. N Engl J Med (2009) 33.09
Acquired copy number alterations in adult acute myeloid leukemia genomes. Proc Natl Acad Sci U S A (2009) 4.17
Whole genome scanning as a cytogenetic tool in hematologic malignancies. Blood (2008) 1.78
Frequent genomic abnormalities in acute myeloid leukemia/myelodysplastic syndrome with normal karyotype. Haematologica (2009) 1.17
A decade of genome-wide gene expression profiling in acute myeloid leukemia: flashback and prospects. Blood (2008) 1.06
Comparative genomic hybridization on microarray (a-CGH) in constitutional and acquired mosaicism may detect as low as 8% abnormal cells. Mol Cytogenet (2011) 1.00
Evidence-based genomic diagnosis characterized chromosomal and cryptic imbalances in 30 elderly patients with myelodysplastic syndrome and acute myeloid leukemia. Mol Cytogenet (2011) 0.99
Chromosomal minimal critical regions in therapy-related leukemia appear different from those of de novo leukemia by high-resolution aCGH. PLoS One (2011) 0.92
Next-generation sequencing of cancer genomes: back to the future. Per Med (2009) 0.86
Array comparative genomic hybridization detects chromosomal abnormalities in hematological cancers that are not detected by conventional cytogenetics. J Mol Diagn (2010) 0.86
Identification of novel genomic aberrations in AML-M5 in a level of array CGH. PLoS One (2014) 0.76
Genomic Copy Number Variations in the Myelodysplastic Syndrome and Acute Myeloid Leukemia Patients with del(5q) and/or -7/del(7q). Int J Med Sci (2015) 0.75
Genomic imbalances are confined to non-proliferating cells in paediatric patients with acute myeloid leukaemia and a normal or incomplete karyotype. PLoS One (2011) 0.75
Coexistence of t(15;17) and t(15;16;17) detected by fluorescence in situ hybridization in a patient with acute promyelocytic leukemia: A case report and literature review. Oncol Lett (2014) 0.75
Submicroscopic deletion of 5q involving tumor suppressor genes (CTNNA1, HSPA9) and copy neutral loss of heterozygosity associated with TET2 and EZH2 mutations in a case of MDS with normal chromosome and FISH results. Mol Cytogenet (2014) 0.75
Localization of a susceptibility locus for Peutz-Jeghers syndrome to 19p using comparative genomic hybridization and targeted linkage analysis. Nat Genet (1997) 4.27
Mutations of the cardiac ryanodine receptor (RyR2) gene in familial polymorphic ventricular tachycardia. Circulation (2001) 3.34
Prognostic subgroups in B-cell chronic lymphocytic leukemia defined by specific chromosomal abnormalities. N Engl J Med (1990) 3.21
Clonal expansion of T/NK-cells during tyrosine kinase inhibitor dasatinib therapy. Leukemia (2009) 2.94
Increased expression of high mobility group A proteins in lung cancer. J Pathol (2006) 2.39
A novel endothelial cell surface receptor tyrosine kinase with extracellular epidermal growth factor homology domains. Mol Cell Biol (1992) 2.34
Rearrangement of ALL1 (MLL) in acute myeloid leukemia with normal cytogenetics. Cancer Res (1998) 2.33
Hepatosplenic candidiasis in patients with acute leukemia: incidence and prognostic implications. Clin Infect Dis (1997) 2.08
Partial tandem duplication of ALL1 as a recurrent molecular defect in acute myeloid leukemia with trisomy 11. Cancer Res (1996) 1.99
Familial aniridia and translocation t(4;11)(q22;p13) without Wilms' tumor. Hum Genet (1983) 1.83
Genetic differences between adenocarcinomas arising in Barrett's esophagus and gastric mucosa. Gastroenterology (2001) 1.74
Identification of a gene at 11q23 encoding a guanine nucleotide exchange factor: evidence for its fusion with MLL in acute myeloid leukemia. Proc Natl Acad Sci U S A (2000) 1.69
Arrhythmic disorder mapped to chromosome 1q42-q43 causes malignant polymorphic ventricular tachycardia in structurally normal hearts. J Am Coll Cardiol (1999) 1.68
DNA gains in 3q occur frequently in squamous cell carcinoma of the lung, but not in adenocarcinoma. Genes Chromosomes Cancer (1998) 1.66
Sinus node function and ventricular repolarization during exercise stress test in long QT syndrome patients with KvLQT1 and HERG potassium channel defects. J Am Coll Cardiol (1999) 1.59
Comparative genomic hybridization reveals complex genetic changes in primary breast cancer tumors and their cell lines. Cancer Genet Cytogenet (2000) 1.59
Concomitant loss of chromosome 3 and whole arm losses and gains of chromosome 1, 6, or 8 in metastasizing primary uveal melanoma. Invest Ophthalmol Vis Sci (2001) 1.57
Changes in gene expression during progression of ovarian carcinoma. Cancer Genet Cytogenet (2001) 1.55
DNA sequence copy number changes in gastrointestinal stromal tumors: tumor progression and prognostic significance. Cancer Res (2000) 1.51
Safety of granulocyte colony-stimulating factor (filgrastim) in intubated patients in the intensive care unit: interim analysis of a prospective, placebo-controlled, double-blind study. Crit Care Med (2000) 1.49
Persistence of the AML1/ETO fusion transcript in patients treated with allogeneic bone marrow transplantation for t(8;21) leukemia. Blood (1996) 1.49
BAALC, the human member of a novel mammalian neuroectoderm gene lineage, is implicated in hematopoiesis and acute leukemia. Proc Natl Acad Sci U S A (2001) 1.48
Amplification and overexpression of p40 subunit of eukaryotic translation initiation factor 3 in breast and prostate cancer. Am J Pathol (1999) 1.42
You may live to the age of more than 100 years even if you are homozygous for a haemochromatosis gene mutation. Eur J Clin Invest (2003) 1.41
Colony formation by megakaryocyte progenitors in myelodysplatic syndromes. Eur J Haematol (1989) 1.39
The inheritance of fragile sites: apparent absence of fra(2)(q13) in the parents of three unrelated probands. J Med Genet (1987) 1.38
Immunophenotyping and molecular cytogenetics. J Histochem Cytochem (1992) 1.38
Effect of activated charcoal on absorption and elimination of phenobarbitone, carbamazepine and phenylbutazone in man. Eur J Clin Pharmacol (1980) 1.38
Lactate dehydrogenase changes during granulocyte colony-stimulating factor treatment. Lancet (1992) 1.37
DNA copy number changes in diffuse large B-cell lymphoma--comparative genomic hybridization study. Blood (1996) 1.34
Gains and losses of DNA sequences in osteosarcomas by comparative genomic hybridization. Cancer Res (1995) 1.34
Reduction of absorption of digoxin, phenytoin and aspirin by activated charcoal in man. Eur J Clin Pharmacol (1978) 1.29
Sotalol and prolonged Q-Tc interval. Lancet (1981) 1.27
DNA copy number amplification profiling of human neoplasms. Oncogene (2006) 1.25
Expression profiling of gastric adenocarcinoma using cDNA array. Int J Cancer (2001) 1.23
Molecular targets for tumour progression in gastrointestinal stromal tumours. Gut (2004) 1.22
Genomewide scan for familial combined hyperlipidemia genes in finnish families, suggesting multiple susceptibility loci influencing triglyceride, cholesterol, and apolipoprotein B levels. Am J Hum Genet (1999) 1.21
A practical metaphase marker of the inactive X chromosome. Am J Hum Genet (1986) 1.20
Gene expression profiling of ameloblastoma and human tooth germ by means of a cDNA microarray. J Dent Res (2002) 1.19
Recurrent DNA copy number changes in 1q, 4q, 6q, 9p, 13q, 14q and 22q detected by comparative genomic hybridization in malignant mesothelioma. Br J Cancer (1997) 1.19
BCL2 overexpression associated with chromosomal amplification in diffuse large B-cell lymphoma. Blood (1997) 1.18
Cytogenetic study of 249 consecutive patients examined for a bone tumor. Cancer Genet Cytogenet (1993) 1.16
Distinct gene expression profiling in chronic lymphocytic leukemia with 11q23 deletion. Leukemia (2001) 1.16
DNA sequence copy number increase at 8q: a potential new prognostic marker in high-grade osteosarcoma. Int J Cancer (1999) 1.15
Recurrent gains of 1q, 8 and 12 in the Ewing family of tumours by comparative genomic hybridization. Br J Cancer (1997) 1.14
Consistent genetic alterations in xenografts of proximal stomach and gastro-esophageal junction adenocarcinomas. Cancer Res (1998) 1.13
Pallister-Killian syndrome: cytogenetic and molecular studies. Clin Genet (1987) 1.13
Ring chromosomes in parosteal osteosarcoma contain sequences from 12q13-15: a combined cytogenetic and comparative genomic hybridization study. Genes Chromosomes Cancer (1996) 1.13
Prognostic impact of chromosomal aberrations in Ewing tumours. Br J Cancer (2002) 1.13
A cluster of seven cases of Clostridium tertium septicemia in neutropenic patients. Eur J Clin Microbiol Infect Dis (1990) 1.12
Expansion of highly differentiated CD8+ T-cells or NK-cells in patients treated with dasatinib is associated with cytomegalovirus reactivation. Leukemia (2011) 1.11
Effect of tricyclic antidepressants and alcohol in psychomotor skills related to driving. Clin Pharmacol Ther (1975) 1.10
Chromosome pulverization in blood diseases. Hereditas (1981) 1.10
Comparative genomic hybridization of malignant fibrous histiocytoma reveals a novel prognostic marker. Am J Pathol (1997) 1.10
Optimization of comparative genomic hybridization using fluorochrome conjugated to dCTP and dUTP nucleotides. Lab Invest (1997) 1.09
DNA copy number changes in thyroid carcinoma. Am J Pathol (1999) 1.09
DNA copy number changes and evaluation of MYC, IGF1R, and FES amplification in xenografts of pancreatic adenocarcinoma. Cancer Genet Cytogenet (2000) 1.09
Different patterns of DNA copy number changes in gastrointestinal stromal tumors, leiomyomas, and schwannomas. Hum Pathol (1998) 1.08
Tumor size-related DNA copy number changes occur in solitary fibrous tumors but not in hemangiopericytomas. Mod Pathol (1997) 1.08
MSX1 gene is deleted in Wolf-Hirschhorn syndrome patients with oligodontia. J Dent Res (2003) 1.08
DNA copy number losses in chromosome 14: an early change in gastrointestinal stromal tumors. Cancer Res (1996) 1.08
Soluble urokinase receptor levels correlate with number of circulating tumor cells in acute myeloid leukemia and decrease rapidly during chemotherapy. Cancer Res (2000) 1.07
11q deletions in hematological malignancies. Leuk Lymphoma (2001) 1.07
Gains, losses, and amplifications of DNA sequences evaluated by comparative genomic hybridization in chondrosarcomas. Am J Pathol (1997) 1.06
17q12-21 amplicon, a novel recurrent genetic change in intestinal type of gastric carcinoma: a comparative genomic hybridization study. Genes Chromosomes Cancer (1997) 1.06
Sotalol intoxication with prolonged Q-T interval and severe tachyarrhythmias. Br Med J (1979) 1.05
Erythroid and granulocyte-macrophage colony formation in myelodysplastic syndromes. Scand J Haematol (1984) 1.03
Overrepresentation of 1q21-23 and 12q13-21 in lipoma-like liposarcomas but not in benign lipomas: a comparative genomic hybridization study. Cancer Genet Cytogenet (1997) 1.03
Survey of the coding region of the HERG gene in long QT syndrome reveals six novel mutations and an amino acid polymorphism with possible phenotypic effects. Hum Mutat (2000) 1.02
1q gain and CDT2 overexpression underlie an aggressive and highly proliferative form of Ewing sarcoma. Oncogene (2011) 1.02
Presence of high-level DNA copy number gains in gastric carcinoma and severely dysplastic adenomas but not in moderately dysplastic adenomas. Cancer Genet Cytogenet (1998) 1.01
Online access to CGH data of DNA sequence copy number changes. Am J Pathol (2000) 1.01
Detection of residual host cells after bone marrow transplantation using non-isotopic in situ hybridization and karyotype analysis. Bone Marrow Transplant (1993) 1.01
Comparison of DNA copy number changes in malignant mesothelioma, adenocarcinoma and large-cell anaplastic carcinoma of the lung. Br J Cancer (1998) 1.00
Impact of malignant stem cell burden on therapy outcome in newly diagnosed chronic myeloid leukemia patients. Leukemia (2013) 1.00
High incidence of PTLD after non-T-cell-depleted allogeneic haematopoietic stem cell transplantation as a consequence of intensive immunosuppressive treatment. Bone Marrow Transplant (2003) 0.99
Clinical correlations of genetic changes by comparative genomic hybridization in Ewing sarcoma and related tumors. Cancer Genet Cytogenet (1999) 0.99
Dedifferentiation of a well-differentiated liposarcoma to a highly malignant metastatic osteosarcoma: amplification of 12q14 at all stages and gain of 1q22-q24 associated with metastases. Cancer Genet Cytogenet (2001) 0.98
Novel findings in gene expression detected in human osteosarcoma by cDNA microarray. Cancer Genet Cytogenet (2000) 0.98
Polyamine deprivation causes major chromosome aberrations in a polyamine-dependent Chinese hamster ovary cell line. Exp Cell Res (1982) 0.98
Mantle cell lymphoma: clinical features, treatment and prognosis of 94 patients. Eur J Cancer (1998) 0.98
Gain of 3q and deletion of 11q22 are frequent aberrations in mantle cell lymphoma. Genes Chromosomes Cancer (1998) 0.98
Restriction landmark genome scanning for aberrant methylation in primary refractory and relapsed acute myeloid leukemia; involvement of the WIT-1 gene. Oncogene (1999) 0.98
Dynamics of the emergence of dasatinib and nilotinib resistance in imatinib-resistant CML patients. Leukemia (2011) 0.97
Radiation-associated sarcomas are characterized by complex karyotypes with frequent rearrangements of chromosome arm 3p. Cancer Genet Cytogenet (2000) 0.97
High-resolution oligonucleotide array-CGH pinpoints genes involved in cryptic losses in chronic lymphocytic leukemia. Cytogenet Genome Res (2007) 0.97
Gains and losses of DNA sequences in liposarcomas evaluated by comparative genomic hybridization. Genes Chromosomes Cancer (1996) 0.97
Evidence for divergence of DNA copy number changes in serous, mucinous and endometrioid ovarian carcinomas. Br J Cancer (1997) 0.97
Autologous stem cell transplantation in adult patients with peripheral T-cell lymphoma: a nation-wide survey. Bone Marrow Transplant (2004) 0.97
DNA copy number changes in development and progression in leiomyosarcomas of soft tissues. Am J Pathol (1998) 0.97
Interphase cytogenetics on paraffin sections of malignant pleural mesothelioma. A comparison to conventional karyotyping and flow cytometric studies. Cancer Genet Cytogenet (1992) 0.97
Central nervous system involvement in patients with mantle cell lymphoma. Ann Hematol (1999) 0.97
An outbreak of invasive aspergillosis in a haematologic unit. Scand J Infect Dis (1987) 0.96
Concomitant DNA copy number amplification at 17q and 22q in dermatofibrosarcoma protuberans. Cytogenet Cell Genet (2001) 0.96
Prolonged Q-T interval and severe tachyarrhythmias, common features of sotalol intoxication. Eur J Clin Pharmacol (1981) 0.96
Response of the QT interval to mental and physical stress in types LQT1 and LQT2 of the long QT syndrome. Heart (2001) 0.95