Synthesis, crystal structure and biological activity of beta-carboline based selective CDK4-cyclin D1 inhibitors.

Fascaplysin as a specific inhibitor for CDK4: insights from molecular modelling. PLoS One (2012) 0.82

4-(3,4-Dihydro-β-carbolin-1-yl)pyrimidin-2-amine. Acta Crystallogr Sect E Struct Rep Online (2009) 0.75

Protein kinases as targets for anticancer agents: from inhibitors to useful drugs. Pharmacol Ther (2002) 1.22

Reassessment of the reaction mechanism in the heme dioxygenases. J Am Chem Soc (2009) 1.11

Structure-based design and synthesis of 2-benzylidene-benzofuran-3-ones as flavopiridol mimics. J Med Chem (2002) 0.93

Enantioselective synthesis of allenamides via sulfimide [2,3]-sigmatropic rearrangement. Org Lett (2009) 0.88

Design, synthesis and biological evaluation of new tryptamine and tetrahydro-beta-carboline-based selective inhibitors of CDK4. Bioorg Med Chem (2008) 0.88

Fascaplysin-inspired diindolyls as selective inhibitors of CDK4/cyclin D1. Bioorg Med Chem (2009) 0.87

Synthesis and biological evaluation of novel flavonols as potential anti-prostate cancer agents. Eur J Med Chem (2012) 0.87

Anticancer effects of the flavonoid diosmetin on cell cycle progression and proliferation of MDA-MB 468 breast cancer cells due to CYP1 activation. Oncol Rep (2009) 0.86

Diasterocontrol in the intramolecular meta-photocycloaddition of arenes and olefines. Photochem Photobiol Sci (2006) 0.83

CA224, a non-planar analogue of fascaplysin, inhibits Cdk4 but not Cdk2 and arrests cells at G0/G1 inhibiting pRB phosphorylation. Bioorg Med Chem Lett (2006) 0.82

Inhibition of cancer cell growth by cyclin dependent kinase 4 inhibitors synthesized based on the structure of fascaplysin. Bioorg Chem (2006) 0.81

New fascaplysin-based CDK4-specific inhibitors: design, synthesis and biological activity. Chem Commun (Camb) (2004) 0.80

Synthesis, glycosidase activity and X-ray crystallography of 3-amino-sugars. Org Biomol Chem (2006) 0.79

Design, synthesis and biological activity of new CDK4-specific inhibitors, based on fascaplysin. Org Biomol Chem (2006) 0.79

Biphenyl-4-carboxylic acid [2-(1H-indol-3-yl)-ethyl]-methylamide (CA224), a nonplanar analogue of fascaplysin, inhibits Cdk4 and tubulin polymerization: evaluation of in vitro and in vivo anticancer activity. J Med Chem (2014) 0.76

Regioselective photo-oxidation of 1-benzyl-4,9-dihydro-3H-beta-carbolines. Chem Commun (Camb) (2006) 0.76

The regiospecific Fischer indole reaction in choline chloride.2ZnCl2 with product isolation by direct sublimation from the ionic liquid. Chem Commun (Camb) (2003) 0.76

The synthesis of fused and spiro annulated carbohydrate structures using copper(I) catalysed intramolecular photoannulation of glucose derivatives. Org Biomol Chem (2004) 0.75

Accessible sugars as asymmetric olefin epoxidation organocatalysts: glucosaminide ketones in the synthesis of terminal epoxides. Org Biomol Chem (2009) 0.75

Enantioselective synthesis of α-alkyl,α-vinyl amino acids via [2,3]-sigmatropic rearrangement of selenimides. Org Lett (2011) 0.75

[2,3]-Sigmatropic rearrangement of allylic selenimides: strategy for the synthesis of peptides, peptidomimetics, and N-aryl vinyl glycines. J Org Chem (2014) 0.75