The Pl(A1/A2) polymorphism of glycoprotein IIIa and cerebrovascular events in hypertension: increased risk of ischemic stroke in high-risk patients.

PubWeight™: 1.35‹?› | Rank: Top 10%

🔗 View Article (PMID 17278970)

Published in J Hypertens on March 01, 2007

Authors

Francesca Lanni1, Gaetano Santulli, Raffaele Izzo, Speranza Rubattu, Bastianina Zanda, Massimo Volpe, Guido Iaccarino, Bruno Trimarco

Author Affiliations

1: Department of Clinical Medicine, Cardiovascular & Immunological Sciences, Federico II University, Naples, Italy.

Articles citing this

CaMK4 Gene Deletion Induces Hypertension. J Am Heart Assoc (2012) 2.14

Endothelial alpha1-adrenoceptors regulate neo-angiogenesis. Br J Pharmacol (2007) 1.22

The GPIIIA PlA2 polymorphism is associated with an increased risk of cardiovascular adverse events. BMC Cardiovasc Disord (2010) 1.12

Physical activity ameliorates cardiovascular health in elderly subjects: the functional role of the β adrenergic system. Front Physiol (2013) 1.03

Efficacy and safety of oral anticoagulants versus aspirin for patients with atrial fibrillation: a meta-analysis. Medicine (Baltimore) (2015) 0.90

The PlA1/A2 polymorphism of glycoprotein IIIa as a risk factor for stroke: a systematic review and meta-analysis. PLoS One (2014) 0.87

Adrenergic signaling in heart failure and cardiovascular aging. Maturitas (2016) 0.84

Recurrent intraventricular thrombus six months after ST-elevation myocardial infarction in a diabetic man: a case report. BMC Res Notes (2013) 0.83

Association of adiponectin with hepatic steatosis: a study of 1,349 subjects in a random population sample. BMC Res Notes (2014) 0.82

Relationship between polymorphisms in beta -2 adrenergic receptor gene and ischemic stroke in North Indian Population: a hospital based case control study. BMC Res Notes (2014) 0.80

Genetics of atherothrombotic and lacunar stroke. Circ Cardiovasc Genet (2009) 0.80

Maintenance of normal blood pressure is dependent on IP3R1-mediated regulation of eNOS. Proc Natl Acad Sci U S A (2016) 0.79

"Addressing the impact of stroke risk factors in a case control study in tertiary care hospitals": a case control study in Tertiary Care Hospitals of Peshawar, Khyber Phukhtoonkhwa (KPK) Pakistan. BMC Res Notes (2013) 0.79

Cardiac Function and Short-Term Outcome in Patients with Acute Ischemic Stroke: A Cross-Sectional Study. J Cardiovasc Dis (2013) 0.78

Association Between Vascular Access Dysfunction and Subsequent Major Adverse Cardiovascular Events in Patients on Hemodialysis: A Population-Based Nested Case-Control Study. Medicine (Baltimore) (2015) 0.77

Hypertension in Malaysia: An Analysis of Trends From the National Surveys 1996 to 2011. Medicine (Baltimore) (2016) 0.77

Association between obesity and high blood pressure among Lithuanian adolescents: a cross-sectional study. Ital J Pediatr (2014) 0.77

Association of Genetic Polymorphisms on VEGFA and VEGFR2 With Risk of Coronary Heart Disease. Medicine (Baltimore) (2016) 0.76

Estimated Glomerular Filtration Rate and Systolic Time Intervals in Risk Stratification for Increased Left Ventricular Mass Index and Left Ventricular Hypertrophy. Medicine (Baltimore) (2016) 0.76

Addressing the relationship between cardiac hypertrophy and ischaemic stroke: an observational study. Int Arch Med (2012) 0.76

Endothelin Type A Receptor Genotype is a Determinant of Quantitative Traits of Metabolic Syndrome in Asian Hypertensive Families: A SAPPHIRe Study. Front Endocrinol (Lausanne) (2013) 0.75

Serum lipocalin-2 levels are positively associated with not only total body fat but also visceral fat area in Chinese men. Medicine (Baltimore) (2016) 0.75

Fixed-Dose Combinations of Renin-Angiotensin System Inhibitors and Calcium Channel Blockers in the Treatment of Hypertension: A Comparison of Angiotensin Receptor Blockers and Angiotensin-Converting Enzyme Inhibitors. Medicine (Baltimore) (2015) 0.75

A Meta-Analysis of Randomized Controlled Trials on Antiplatelet Agents Versus Placebo/Control for Treating Peripheral Artery Disease. Medicine (Baltimore) (2015) 0.75

Prognostic Value of Plasma Intermedin Level in Patients With Non-ST-Segment Elevation Acute Coronary Syndrome. Medicine (Baltimore) (2016) 0.75

The Prognostic Role of Angiotensin II Type 1 Receptor Autoantibody in Non-Gravid Hypertension and Pre-eclampsia: A Meta-analysis and Our Studies. Medicine (Baltimore) (2016) 0.75

Genetic Association Studies Reporting on Variants in the C-Reactive Protein Gene and Coronary Artery Disease: A Meta-Analysis. Medicine (Baltimore) (2015) 0.75

Increased mean aliphatic lipid chain length in left ventricular hypertrophy secondary to arterial hypertension: A cross-sectional study. Medicine (Baltimore) (2016) 0.75

Comparative clinical implications of admission electrocardiographic findings for patients with non-ST-segment elevation myocardial infarction. Medicine (Baltimore) (2016) 0.75

Effect of multiple clinical factors on recurrent angina after percutaneous coronary intervention: A retrospective study from 398 ST-segment elevation myocardial infarction patients. Medicine (Baltimore) (2016) 0.75

A propensity score-matching analysis of transthoracic echocardiography and abdominal ultrasonography for the detection of abdominal aortic aneurysms. Clin Med Insights Cardiol (2015) 0.75

Effects of liraglutide on hemodynamic parameters in patients with heart failure. Oncotarget (2017) 0.75

Articles by these authors

2013 ESH/ESC guidelines for the management of arterial hypertension: the Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). Eur Heart J (2013) 12.73

Guidelines on diabetes, pre-diabetes, and cardiovascular diseases: executive summary. The Task Force on Diabetes and Cardiovascular Diseases of the European Society of Cardiology (ESC) and of the European Association for the Study of Diabetes (EASD). Eur Heart J (2007) 9.80

Effects of Proprotein Convertase Subtilisin/Kexin Type 9 Antibodies in Adults With Hypercholesterolemia: A Systematic Review and Meta-analysis. Ann Intern Med (2015) 4.62

Benefits of statins in elderly subjects without established cardiovascular disease: a meta-analysis. J Am Coll Cardiol (2013) 3.61

Akt induces enhanced myocardial contractility and cell size in vivo in transgenic mice. Proc Natl Acad Sci U S A (2002) 3.18

Antihypertensive treatment and development of heart failure in hypertension: a Bayesian network meta-analysis of studies in patients with hypertension and high cardiovascular risk. Arch Intern Med (2010) 3.15

High glucose causes upregulation of cyclooxygenase-2 and alters prostanoid profile in human endothelial cells: role of protein kinase C and reactive oxygen species. Circulation (2003) 2.44

Elevated myocardial and lymphocyte GRK2 expression and activity in human heart failure. Eur Heart J (2005) 2.29

CaMK4 Gene Deletion Induces Hypertension. J Am Heart Assoc (2012) 2.14

G-protein-coupled receptor kinase 2 and hypertension: molecular insights and pathophysiological mechanisms. High Blood Press Cardiovasc Prev (2013) 2.13

Differential roles of GSK-3β during myocardial ischemia and ischemia/reperfusion. Circ Res (2011) 2.10

Akt mediates the cross-talk between beta-adrenergic and insulin receptors in neonatal cardiomyocytes. Circ Res (2004) 2.08

Ambulatory blood pressure values in the Ongoing Telmisartan Alone and in Combination with Ramipril Global Endpoint Trial (ONTARGET). Hypertension (2012) 2.02

Association of atrial natriuretic peptide and type a natriuretic peptide receptor gene polymorphisms with left ventricular mass in human essential hypertension. J Am Coll Cardiol (2006) 1.98

Initial left-ventricular mass predicts probability of uncontrolled blood pressure in arterial hypertension. J Hypertens (2011) 1.97

Expert consensus document from the European Society of Cardiology on catheter-based renal denervation. Eur Heart J (2013) 1.90

Selective inhibition of protein kinase Cbeta2 prevents acute effects of high glucose on vascular cell adhesion molecule-1 expression in human endothelial cells. Circulation (2004) 1.88

Gene silencing of the mitochondrial adaptor p66(Shc) suppresses vascular hyperglycemic memory in diabetes. Circ Res (2012) 1.85

Angiotensin type 2 receptor in resistance arteries of type 2 diabetic hypertensive patients. Hypertension (2006) 1.80

Tolerability of long-term treatment with lercanidipine versus amlodipine and lacidipine in elderly hypertensives. Am J Hypertens (2002) 1.74

Deletion of p66shc gene protects against age-related endothelial dysfunction. Circulation (2004) 1.69

Leptin effect on endothelial nitric oxide is mediated through Akt-endothelial nitric oxide synthase phosphorylation pathway. Diabetes (2002) 1.65

Effects of Ile164 polymorphism of beta2-adrenergic receptor gene on coronary artery disease. J Am Coll Cardiol (2008) 1.65

Genetic deletion of p66(Shc) adaptor protein prevents hyperglycemia-induced endothelial dysfunction and oxidative stress. Proc Natl Acad Sci U S A (2007) 1.63

Assessment of flow-mediated dilation reproducibility: a nationwide multicenter study. J Hypertens (2012) 1.62

Endothelial cells are able to synthesize and release catecholamines both in vitro and in vivo. Hypertension (2012) 1.62

Circulating biomarkers with preventive, diagnostic and prognostic implications in cardiovascular diseases. Int J Cardiol (2011) 1.62

Mammalian target of rapamycin signaling in cardiac physiology and disease. Circ Res (2014) 1.59

Ischemic neoangiogenesis enhanced by beta2-adrenergic receptor overexpression: a novel role for the endothelial adrenergic system. Circ Res (2005) 1.57

Coronary heart disease risk factors and mortality. JAMA (2012) 1.56

Rheb is a critical regulator of autophagy during myocardial ischemia: pathophysiological implications in obesity and metabolic syndrome. Circulation (2012) 1.56

Increased basal nitric oxide release despite enhanced free radical production in hypertension. J Hypertens (2002) 1.54

Induction of mitogen-activated protein kinases is proportional to the amount of pressure overload. Hypertension (2009) 1.53

Genetic polymorphism of the renin-angiotensin-aldosterone system and arterial hypertension in the Italian population: the GENIPER Project. J Hypertens (2003) 1.52

A selective microRNA-based strategy inhibits restenosis while preserving endothelial function. J Clin Invest (2014) 1.52

Integrating cardiac PIP3 and cAMP signaling through a PKA anchoring function of p110γ. Mol Cell (2011) 1.52

Cardiovascular health in migrants: current status and issues for prevention. A collaborative multidisciplinary task force report. J Cardiovasc Med (Hagerstown) (2014) 1.50

Angiotensin receptor blockers: therapeutic targets and cardiovascular protection. Blood Press (2005) 1.49

Do diabetes, metabolic syndrome or their association equally affect biventricular function? A tissue Doppler study. Hypertens Res (2012) 1.49

SOCS1 gene transfer accelerates the transition to heart failure through the inhibition of the gp130/JAK/STAT pathway. Cardiovasc Res (2012) 1.48

Left bundle-branch block--pathophysiology, prognosis, and clinical management. Clin Cardiol (2007) 1.48

Nitric-oxide-mediated relaxations in salt-induced hypertension: effect of chronic beta1 -selective receptor blockade. J Hypertens (2002) 1.47

Cardiovascular risk in relation to a new classification of hypertensive left ventricular geometric abnormalities. J Hypertens (2015) 1.47

Intracardiac injection of AdGRK5-NT reduces left ventricular hypertrophy by inhibiting NF-kappaB-dependent hypertrophic gene expression. Hypertension (2010) 1.47

Angiotensin II receptor blockers and myocardial infarction: deeds and misdeeds. J Hypertens (2005) 1.47

Hypertensive target organ damage predicts incident diabetes mellitus. Eur Heart J (2013) 1.47

Functional cross-talk between angiotensin II and epidermal growth factor receptors in NIH3T3 fibroblasts. J Hypertens (2002) 1.46

An exaggerated systolic blood pressure response to exercise is associated with cardiovascular remodeling in subjects with prehypertension. Ital Heart J (2005) 1.45

The adipokine visfatin induces tissue factor expression in human coronary artery endothelial cells: another piece in the adipokines puzzle. Thromb Res (2012) 1.45

Hypertension guidelines: criteria that might make them more clinically useful. Am J Hypertens (2002) 1.45

The G-protein-coupled receptor kinase 5 inhibits NFkappaB transcriptional activity by inducing nuclear accumulation of IkappaB alpha. Proc Natl Acad Sci U S A (2008) 1.44

Are observational studies more informative than randomized controlled trials in hypertension? Pro side of the argument. Hypertension (2013) 1.44

Natriuretic peptides: an update on bioactivity, potential therapeutic use, and implication in cardiovascular diseases. Am J Hypertens (2008) 1.44

Mortality reduction with transradial approach in patients with ST-segment elevation myocardial infarction: is the randomized evidence conclusive? Int J Cardiol (2013) 1.43

TET2 and CSMD1 genes affect SBP response to hydrochlorothiazide in never-treated essential hypertensives. J Hypertens (2015) 1.43

Rethinking targets of blood pressure and guidelines for hypertension clinical management. Nephrol Dial Transplant (2010) 1.42

Role of echocardiography and carotid ultrasonography in stratifying risk in patients with essential hypertension: the Assessment of Prognostic Risk Observational Survey. J Hypertens (2002) 1.41

Altered regulation of endothelin A receptor subtype in the cerebral arterioles in response to a Japanese-style diet, in stroke-prone hypertensive rats. J Hypertens (2003) 1.41

Blood pressure control according to new guidelines targets in low- to high-risk hypertensives managed in specialist practice. J Hypertens (2004) 1.41

Effects of a new combination of nutraceuticals with Morus alba on lipid profile, insulin sensitivity and endotelial function in dyslipidemic subjects. A cross-over, randomized, double-blind trial. High Blood Press Cardiovasc Prev (2015) 1.40

Microalbuminuria predicts the recurrence of cardiovascular events in patients with essential hypertension. J Hypertens (2016) 1.40

The management of the type 2 diabetic patient with hypertension - too late and too little: suggested improvements. Blood Press (2008) 1.40

Lack of protective role of HDL-C in patients with coronary artery disease undergoing elective coronary artery bypass grafting. Eur Heart J (2013) 1.40

Olmesartan-based therapies: an effective way to improve blood pressure control and cardiovascular protection. J Hypertens (2013) 1.39

[Hypertensive heart disease: diagnostic and therapeutic guidelines]. G Ital Cardiol (Rome) (2008) 1.39

Antihypertensive efficacy of olmesartan medoxomil and ramipril in elderly patients with mild to moderate hypertension grouped according to renal function status : a retrospective analysis. High Blood Press Cardiovasc Prev (2013) 1.39

Calcium release channel RyR2 regulates insulin release and glucose homeostasis. J Clin Invest (2015) 1.38

Targeting angiogenesis: structural characterization and biological properties of a de novo engineered VEGF mimicking peptide. Proc Natl Acad Sci U S A (2005) 1.38

Arterial stiffness as an independent predictor of longitudinal changes in cognitive function in the older individual. J Hypertens (2007) 1.32

New susceptibility locus for hypertension on chromosome 8q by efficient pedigree-breaking in an Italian isolate. Hum Mol Genet (2006) 1.29

In vivo properties of the proangiogenic peptide QK. J Transl Med (2009) 1.26

Pinpointing beta adrenergic receptor in ageing pathophysiology: victim or executioner? Evidence from crime scenes. Immun Ageing (2013) 1.24

Activation of NADPH oxidase 4 in the endoplasmic reticulum promotes cardiomyocyte autophagy and survival during energy stress through the protein kinase RNA-activated-like endoplasmic reticulum kinase/eukaryotic initiation factor 2α/activating transcription factor 4 pathway. Circ Res (2013) 1.24

G protein-coupled receptor kinase 2 activity impairs cardiac glucose uptake and promotes insulin resistance after myocardial ischemia. Circulation (2011) 1.23

Atrial natriuretic peptide gene polymorphisms and risk of ischemic stroke in humans. Stroke (2004) 1.22

Arterial stiffness is an independent risk factor for cognitive impairment in the elderly: a pilot study. J Hypertens (2005) 1.22