Joseph D Smith

Author PubWeight™ 51.36‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A family affair: var genes, PfEMP1 binding, and malaria disease. Curr Opin Microbiol 2006 2.93
2 Evidence for the importance of genetic structuring to the structural and functional specialization of the Plasmodium falciparum var gene family. Mol Microbiol 2003 2.92
3 Severe malaria is associated with parasite binding to endothelial protein C receptor. Nature 2013 2.86
4 Widespread functional specialization of Plasmodium falciparum erythrocyte membrane protein 1 family members to bind CD36 analysed across a parasite genome. Mol Microbiol 2003 2.46
5 Global genetic diversity and evolution of var genes associated with placental and severe childhood malaria. Mol Biochem Parasitol 2006 2.24
6 Identification of multiple chondroitin sulfate A (CSA)-binding domains in the var2CSA gene transcribed in CSA-binding parasites. J Infect Dis 2005 2.24
7 Patterns of gene recombination shape var gene repertoires in Plasmodium falciparum: comparisons of geographically diverse isolates. BMC Genomics 2007 2.23
8 A restricted subset of var genes mediates adherence of Plasmodium falciparum-infected erythrocytes to brain endothelial cells. Proc Natl Acad Sci U S A 2012 1.90
9 Structural polymorphism and diversifying selection on the pregnancy malaria vaccine candidate VAR2CSA. Mol Biochem Parasitol 2007 1.86
10 Antigenic variation in Plasmodium falciparum: gene organization and regulation of the var multigene family. Eukaryot Cell 2007 1.58
11 Investigating the host binding signature on the Plasmodium falciparum PfEMP1 protein family. PLoS Pathog 2011 1.53
12 Mapping a common interaction site used by Plasmodium falciparum Duffy binding-like domains to bind diverse host receptors. Mol Microbiol 2007 1.42
13 Disruption of var2csa gene impairs placental malaria associated adhesion phenotype. PLoS One 2007 1.29
14 Evidence for globally shared, cross-reacting polymorphic epitopes in the pregnancy-associated malaria vaccine candidate VAR2CSA. Infect Immun 2008 1.29
15 Identification of a 67-amino-acid region of the Plasmodium falciparum variant surface antigen that binds chondroitin sulphate A and elicits antibodies reactive with the surface of placental isolates. Mol Microbiol 2004 1.22
16 VAR2CSA domains expressed in Escherichia coli induce cross-reactive antibodies to native protein. J Infect Dis 2008 1.20
17 Immunization with VAR2CSA-DBL5 recombinant protein elicits broadly cross-reactive antibodies to placental Plasmodium falciparum-infected erythrocytes. Infect Immun 2010 1.18
18 Evaluation of the antigenic diversity of placenta-binding Plasmodium falciparum variants and the antibody repertoire among pregnant women. Infect Immun 2010 1.15
19 High levels of antibodies to multiple domains and strains of VAR2CSA correlate with the absence of placental malaria in Cameroonian women living in an area of high Plasmodium falciparum transmission. Infect Immun 2012 1.15
20 Pregnancy-associated malaria: parasite binding, natural immunity and vaccine development. Int J Parasitol 2006 1.09
21 High avidity antibodies to full-length VAR2CSA correlate with absence of placental malaria. PLoS One 2012 1.09
22 DC8 and DC13 var genes associated with severe malaria bind avidly to diverse endothelial cells. PLoS Pathog 2013 1.03
23 Functional interdependence of the DBLbeta domain and c2 region for binding of the Plasmodium falciparum variant antigen to ICAM-1. Mol Biochem Parasitol 2004 1.02
24 Antibodies to a full-length VAR2CSA immunogen are broadly strain-transcendent but do not cross-inhibit different placental-type parasite isolates. PLoS One 2011 1.00
25 Disguising itself--insights into Plasmodium falciparum binding and immune evasion from the DBL crystal structure. Mol Biochem Parasitol 2006 0.97
26 Multilaboratory approach to preclinical evaluation of vaccine immunogens for placental malaria. Infect Immun 2012 0.94
27 Spatial and temporal mapping of the PfEMP1 export pathway in Plasmodium falciparum. Cell Microbiol 2013 0.93
28 Induction of strain-transcendent antibodies to placental-type isolates with VAR2CSA DBL3 or DBL5 recombinant proteins. Malar J 2011 0.91
29 Optimizing expression of the pregnancy malaria vaccine candidate, VAR2CSA in Pichia pastoris. Malar J 2009 0.91
30 Branch point identification and sequence requirements for intron splicing in Plasmodium falciparum. Eukaryot Cell 2011 0.87
31 Identification of a role for the PfEMP1 semi-conserved head structure in protein trafficking to the surface of Plasmodium falciparum infected red blood cells. Cell Microbiol 2010 0.86
32 Advances and challenges in malaria vaccine development. Expert Rev Mol Med 2009 0.86
33 Induction of crossreactive antibodies against the Plasmodium falciparum variant protein. Proc Natl Acad Sci U S A 2003 0.84
34 Glycan masking of Plasmodium vivax Duffy Binding Protein for probing protein binding function and vaccine development. PLoS Pathog 2013 0.84
35 New tools to identify var sequence tags and clone full-length genes using type-specific primers to Duffy binding-like domains. Mol Biochem Parasitol 2003 0.84
36 Identification of VAR2CSA domain-specific inhibitory antibodies of the Plasmodium falciparum erythrocyte membrane protein 1 using a novel flow cytometry assay. Clin Vaccine Immunol 2013 0.83
37 Clonal variants of Plasmodium falciparum exhibit a narrow range of rolling velocities to host receptor CD36 under dynamic flow conditions. Eukaryot Cell 2013 0.78
38 Infected erythrocyte binding to hyaluronic acid and malaria in pregnant women. J Infect Dis 2004 0.75