Mechanisms of exposure therapy: how neuroscience can improve psychological treatments for anxiety disorders.

PubWeight™: 1.65‹?› | Rank: Top 3%

🔗 View Article (PMID 17292521)

Published in Clin Psychol Rev on January 18, 2007

Authors

Richard J McNally1

Author Affiliations

1: Department of Psychology, Harvard University, 33 Kirkland Street, Cambridge, MA 02138 USA. rjm@wjh.harvard.edu

Articles citing this

Functional connectivity of the human amygdala using resting state fMRI. Neuroimage (2008) 3.76

Calcium-permeable AMPA receptor dynamics mediate fear memory erasure. Science (2010) 3.13

Cognitive enhancement as a pharmacotherapy target for stimulant addiction. Addiction (2010) 2.04

The study of fear extinction: implications for anxiety disorders. Am J Psychiatry (2011) 1.60

Cognitive enhancement as a treatment for drug addictions. Neuropharmacology (2012) 1.54

Antidepressant medication augmented with cognitive-behavioral therapy for generalized anxiety disorder in older adults. Am J Psychiatry (2013) 1.50

Effects of post-session administration of methylene blue on fear extinction and contextual memory in adults with claustrophobia. Am J Psychiatry (2014) 1.48

Attention biases, anxiety, and development: toward or away from threats or rewards? Depress Anxiety (2011) 1.37

Glucocorticoids enhance extinction-based psychotherapy. Proc Natl Acad Sci U S A (2011) 1.33

The amygdala and medial prefrontal cortex: partners in the fear circuit. J Physiol (2013) 1.25

Exposure therapy triggers lasting reorganization of neural fear processing. Proc Natl Acad Sci U S A (2012) 1.06

A lifespan view of anxiety disorders. Dialogues Clin Neurosci (2011) 1.04

Fibroblast growth factor-2 enhances extinction and reduces renewal of conditioned fear. Neuropsychopharmacology (2010) 1.00

Sleep promotes consolidation and generalization of extinction learning in simulated exposure therapy for spider fear. J Psychiatr Res (2012) 0.99

Attention training for reducing spider fear in spider-fearful individuals. J Anxiety Disord (2010) 0.98

Prefrontal cortical contributions during discriminative fear conditioning, extinction, and spontaneous recovery in rats. Exp Brain Res (2010) 0.94

Somatic experiencing: using interoception and proprioception as core elements of trauma therapy. Front Psychol (2015) 0.93

Cognitive function as an emerging treatment target for marijuana addiction. Exp Clin Psychopharmacol (2010) 0.90

Effects of sleep on memory for conditioned fear and fear extinction. Psychol Bull (2015) 0.90

Cognitive-behavioral therapy for anxiety in children with high-functioning autism: a meta-analysis. Pediatrics (2013) 0.89

The impact of perception and presence on emotional reactions: a review of research in virtual reality. Front Psychol (2015) 0.88

Sleep and REM sleep disturbance in the pathophysiology of PTSD: the role of extinction memory. Biol Mood Anxiety Disord (2015) 0.87

Galantamine improves sustained attention in chronic cocaine users. Exp Clin Psychopharmacol (2011) 0.87

Extinction of conditioned fear is better learned and recalled in the morning than in the evening. J Psychiatr Res (2013) 0.85

Repetitive TMS combined with exposure therapy for PTSD: a preliminary study. J Anxiety Disord (2008) 0.84

Unpaired extinction: implications for treating post-traumatic stress disorder. J Psychiatr Res (2010) 0.83

Translating findings from basic fear research to clinical psychiatry in Puerto Rico. P R Health Sci J (2007) 0.82

Augmenting antidepressant medication with modular CBT for geriatric generalized anxiety disorder: a pilot study. Int J Geriatr Psychiatry (2010) 0.82

Emerging interventions for PTSD: future directions for clinical care and research. Neuropharmacology (2011) 0.81

Coping changes the brain. Front Behav Neurosci (2013) 0.81

Predicting return of fear following exposure therapy with an implicit measure of attitudes. Behav Res Ther (2012) 0.81

Coping and glucocorticoid receptor regulation by stress inoculation. Psychoneuroendocrinology (2014) 0.81

Combat posttraumatic stress disorder, substance use disorders, and traumatic brain injury. J Addict Med (2009) 0.80

Does fear reactivity during exposure predict panic symptom reduction? J Consult Clin Psychol (2012) 0.80

Relationship between fear conditionability and aversive memories: evidence from a novel conditioned-intrusion paradigm. PLoS One (2013) 0.80

Stress, glucocorticoids and memory: implications for treating fear-related disorders. Nat Rev Neurosci (2016) 0.80

Prefrontal dopamine regulates fear reinstatement through the downregulation of extinction circuits. Elife (2015) 0.79

Snake fearfulness is associated with sustained competitive biases to visual snake features: hypervigilance without avoidance. Psychiatry Res (2014) 0.79

Classical conditioning and conditioning-specific reflex modification of rabbit heart rate as a function of unconditioned stimulus location. Behav Neurosci (2011) 0.78

Stress inoculation modeled in mice. Transl Psychiatry (2015) 0.78

Enduring abolishment of remote but not recent expression of conditioned fear by the blockade of calcium-permeable AMPA receptors before extinction training. Psychopharmacology (Berl) (2016) 0.77

The Future of D-Cycloserine and Other Cognitive Modifiers in Obsessive-Compulsive and Related Disorders. Curr Psychiatry Rev (2014) 0.77

Eyeblink classical conditioning and post-traumatic stress disorder - a model systems approach. Front Psychiatry (2015) 0.76

Interactions of time of day and sleep with between-session habituation and extinction memory in young adult males. Exp Brain Res (2014) 0.76

Therapeutic Effects of Extinction Learning as a Model of Exposure Therapy in Rats. Neuropsychopharmacology (2016) 0.76

Learning to like disgust: neuronal correlates of counterconditioning. Front Hum Neurosci (2013) 0.75

No effect of glucose administration in a novel contextual fear generalization protocol in rats. Transl Psychiatry (2016) 0.75

The preparatory set: a novel approach to understanding stress, trauma, and the bodymind therapies. Front Hum Neurosci (2015) 0.75

Novel response patterns during repeated presentation of affective and neutral stimuli. Soc Cogn Affect Neurosci (2016) 0.75

Striatal dopamine D2/3 receptor regulation by stress inoculation in squirrel monkeys. Neurobiol Stress (2016) 0.75

Depotentiation from Potentiated Synaptic Strength in a Tristable System of Coupled Phosphatase and Kinase. Front Comput Neurosci (2016) 0.75

CBT reduces CBF: cognitive-behavioral therapy reduces cerebral blood flow in fear-relevant brain regions in spider phobia. Brain Behav (2016) 0.75

Translation of associative learning models into extinction reminders delivered via mobile phones during cue exposure interventions for substance use. Psychol Addict Behav (2014) 0.75

Passive avoidance is linked to impaired fear extinction in humans. Learn Mem (2013) 0.75

Advances in fMRI Real-Time Neurofeedback. Trends Cogn Sci (2017) 0.75

Enhanced Risk Aversion, But Not Loss Aversion, in Unmedicated Pathological Anxiety. Biol Psychiatry (2016) 0.75

Low-dose systemic scopolamine disrupts context conditioning in rats. J Psychopharmacol (2017) 0.75