Published in Circulation on February 19, 2007
Basic science of pulmonary arterial hypertension for clinicians: new concepts and experimental therapies. Circulation (2010) 2.85
Molecular pathogenesis of pulmonary arterial hypertension. J Clin Invest (2008) 2.49
Pulmonary arterial remodeling induced by a Th2 immune response. J Exp Med (2008) 2.08
Autophagic protein LC3B confers resistance against hypoxia-induced pulmonary hypertension. Am J Respir Crit Care Med (2010) 1.93
Pathogenic mechanisms of pulmonary arterial hypertension. J Mol Cell Cardiol (2007) 1.85
Gastrointestinal dysfunction in mice with a targeted mutation in the gene encoding vasoactive intestinal polypeptide: a model for the study of intestinal ileus and Hirschsprung's disease. Peptides (2007) 1.36
Schistosomiasis-induced experimental pulmonary hypertension: role of interleukin-13 signaling. Am J Pathol (2010) 1.33
A brief overview of mouse models of pulmonary arterial hypertension: problems and prospects. Am J Physiol Lung Cell Mol Physiol (2012) 1.18
Development of pulmonary arterial hypertension in mice over-expressing S100A4/Mts1 is specific to females. Respir Res (2011) 1.11
Estrogens and development of pulmonary hypertension: interaction of estradiol metabolism and pulmonary vascular disease. J Cardiovasc Pharmacol (2010) 1.08
Elastin insufficiency predisposes to elevated pulmonary circulatory pressures through changes in elastic artery structure. J Appl Physiol (1985) (2008) 1.04
Immune and inflammatory mechanisms in pulmonary arterial hypertension. Prog Cardiovasc Dis (2012) 1.03
PKA-dependent activation of the vascular smooth muscle isoform of KATP channels by vasoactive intestinal polypeptide and its effect on relaxation of the mesenteric resistance artery. Biochim Biophys Acta (2007) 0.98
Serotonin transporter, sex, and hypoxia: microarray analysis in the pulmonary arteries of mice identifies genes with relevance to human PAH. Physiol Genomics (2011) 0.97
Vasoactive intestinal peptide loss leads to impaired CNS parenchymal T-cell infiltration and resistance to experimental autoimmune encephalomyelitis. Proc Natl Acad Sci U S A (2010) 0.97
Paigen diet-fed apolipoprotein E knockout mice develop severe pulmonary hypertension in an interleukin-1-dependent manner. Am J Pathol (2011) 0.97
Asthma and pulmonary arterial hypertension: do they share a key mechanism of pathogenesis? Eur Respir J (2010) 0.95
Targeting the adventitial microenvironment in pulmonary hypertension: A potential approach to therapy that considers epigenetic change. Pulm Circ (2012) 0.94
A comprehensive review: the evolution of animal models in pulmonary hypertension research; are we there yet? Pulm Circ (2013) 0.94
Treating pulmonary arterial hypertension: current treatments and future prospects. Ther Adv Chronic Dis (2011) 0.93
Neprilysin null mice develop exaggerated pulmonary vascular remodeling in response to chronic hypoxia. Am J Pathol (2009) 0.92
Cyclooxygenase-2 inhibition and hypoxia-induced pulmonary hypertension: effects on pulmonary vascular remodeling and contractility. Trends Cardiovasc Med (2009) 0.92
Structure and composition of pulmonary arteries, capillaries, and veins. Compr Physiol (2012) 0.91
Perspective: ambient air pollution: inflammatory response and effects on the lung's vasculature. Pulm Circ (2014) 0.91
Circadian regulation of cardiovascular function: a role for vasoactive intestinal peptide. Am J Physiol Heart Circ Physiol (2010) 0.90
Genetically manipulated mouse models of lung disease: potential and pitfalls. Am J Physiol Lung Cell Mol Physiol (2011) 0.90
Anticipated classes of new medications and molecular targets for pulmonary arterial hypertension. Pulm Circ (2013) 0.90
New perspectives for the treatment of pulmonary hypertension. Br J Pharmacol (2011) 0.87
Absence of the adenosine A2A receptor confers pulmonary arterial hypertension and increased pulmonary vascular remodeling in mice. J Vasc Res (2010) 0.86
VIP and endothelin receptor antagonist: an effective combination against experimental pulmonary arterial hypertension. Respir Res (2011) 0.85
Translating Research into Improved Patient Care in Pulmonary Arterial Hypertension. Am J Respir Crit Care Med (2016) 0.84
VIP gene deletion in mice causes cardiomyopathy associated with upregulation of heart failure genes. PLoS One (2013) 0.83
The absence of the VPAC(2) receptor does not protect mice from Aspergillus induced allergic asthma. Peptides (2010) 0.82
A process-based review of mouse models of pulmonary hypertension. Pulm Circ (2012) 0.82
Pulmonary arterial hypertension in adults: novel drugs and catheter ablation techniques show promise? Systematic review on pharmacotherapy and interventional strategies. Biomed Res Int (2014) 0.82
Defective pulmonary innervation and autonomic imbalance in congenital diaphragmatic hernia. Am J Physiol Lung Cell Mol Physiol (2011) 0.81
17β-estradiol protects the lung against acute injury: possible mediation by vasoactive intestinal polypeptide. Endocrinology (2011) 0.81
VIP Regulates the Development & Proliferation of Treg in vivo in spleen. Allergy Asthma Clin Immunol (2011) 0.81
Gene expression in lungs of mice lacking the 5-hydroxytryptamine transporter gene. BMC Pulm Med (2009) 0.80
Pharmacogenomics in pulmonary arterial hypertension: Toward a mechanistic, target-based approach to therapy. Pulm Circ (2011) 0.80
Animal Models of Pulmonary Hypertension: Matching Disease Mechanisms to Etiology of the Human Disease. J Pulm Respir Med (2014) 0.80
Vasoactive intestinal peptide signaling axis in human leukemia. World J Biol Chem (2011) 0.79
Adenoviral transfer of vasoactive intestinal peptide (VIP) gene inhibits rat aortic and pulmonary artery smooth muscle cell proliferation. Peptides (2009) 0.79
Prospect of vasoactive intestinal peptide therapy for COPD/PAH and asthma: a review. Respir Res (2011) 0.79
Pulmonary hypertension in women. Expert Rev Cardiovasc Ther (2010) 0.79
Gene Deletion of VIP Leads to Increased Mortality Associated with Progressive Right Ventricular Hypertrophy. J Cardiovasc Dis (2014) 0.78
Emerging Novel Therapies for Heart Failure. Clin Med Insights Cardiol (2015) 0.78
Vasodilatory effect of the stable vasoactive intestinal peptide analog RO 25-1553 in murine and rat lungs. PLoS One (2013) 0.76
Pulmonary vascular disease related to hemodynamic stress in the pulmonary circulation. Compr Physiol (2011) 0.75
Cystic fibrosis transmembrane conductance regulator dysfunction in VIP knockout mice. Am J Physiol Cell Physiol (2014) 0.75
Vasoactive intestinal Peptide inhaled agonists: potential role in respiratory therapeutics. Hippokratia (2013) 0.75
Disrupted circadian rhythms in VIP- and PHI-deficient mice. Am J Physiol Regul Integr Comp Physiol (2003) 3.37
Pericardial cyst: case reports and a literature review. Echocardiography (2004) 3.09
Focused cardiac ultrasound in the emergent setting: a consensus statement of the American Society of Echocardiography and American College of Emergency Physicians. J Am Soc Echocardiogr (2010) 2.73
Aerosolized antibiotics and ventilator-associated tracheobronchitis in the intensive care unit. Crit Care Med (2008) 2.65
Incidence and risk of hypertension with sorafenib in patients with cancer: a systematic review and meta-analysis. Lancet Oncol (2008) 2.63
Mutational signature of aristolochic acid exposure as revealed by whole-exome sequencing. Sci Transl Med (2013) 2.30
Aristolactam-DNA adducts are a biomarker of environmental exposure to aristolochic acid. Kidney Int (2011) 2.28
Multistate analysis of factors associated with intimate partner violence. Am J Prev Med (2002) 2.22
Class III PI3K Vps34 plays an essential role in autophagy and in heart and liver function. Proc Natl Acad Sci U S A (2012) 2.14
Endemic nephropathy: the case for chronic poisoning by aristolochia. Croat Med J (2005) 2.03
Suppression of phosphoinositide 3-kinase signaling and alteration of multiple ion currents in drug-induced long QT syndrome. Sci Transl Med (2012) 1.99
Maternal embryonic leucine zipper kinase is a key regulator of the proliferation of malignant brain tumors, including brain tumor stem cells. J Neurosci Res (2008) 1.96
The class IA phosphatidylinositol 3-kinase p110-beta subunit is a positive regulator of autophagy. J Cell Biol (2010) 1.91
Aristolochic acid-associated urothelial cancer in Taiwan. Proc Natl Acad Sci U S A (2012) 1.82
PI 3-kinase regulation of dopamine uptake. J Neurochem (2002) 1.64
Pharmacology and functions of receptors for vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide: IUPHAR review 1. Br J Pharmacol (2012) 1.64
The effect of acellular dermal matrix use on complication rates in tissue expander/implant breast reconstruction. Ann Plast Surg (2010) 1.61
Neuropeptide PACAP in mouse liver ischemia and reperfusion injury: immunomodulation by the cAMP-PKA pathway. Hepatology (2013) 1.60
Amplitude and phase of cerebrospinal fluid pulsations: experimental studies and review of the literature. J Neurosurg (2006) 1.59
Respiratory symptoms necessitating spirometry among soldiers with Iraq/Afghanistan war lung injury. J Occup Environ Med (2011) 1.53
Rapamycin and mTOR kinase inhibitors. J Chem Biol (2008) 1.51
Impact of shared epitope genotype and ethnicity on erosive disease: a meta-analysis of 3,240 rheumatoid arthritis patients. Arthritis Rheum (2004) 1.50
ADAMTS13 is expressed in hepatic stellate cells. Lab Invest (2005) 1.49
Arsenic in drinking water and stroke hospitalizations in Michigan. Stroke (2010) 1.49
Akt and c-Myc differentially activate cellular metabolic programs and prime cells to bioenergetic inhibition. J Biol Chem (2009) 1.48
The risk of the development of aortic stenosis in patients with "benign" aortic valve thickening. Arch Intern Med (2002) 1.48
A coupled level set framework for bladder wall segmentation with application to MR cystography. IEEE Trans Med Imaging (2010) 1.44
Removal of lead contaminated dusts from hard surfaces. Environ Sci Technol (2006) 1.38
Rate and associations of epididymal cysts on pediatric scrotal ultrasound. J Urol (2010) 1.38
Mice lacking the VIP gene show airway hyperresponsiveness and airway inflammation, partially reversible by VIP. Am J Physiol Lung Cell Mol Physiol (2006) 1.38
A provider intervention to improve colorectal cancer screening in county health centers. Med Care (2008) 1.36
Isolation of circulating epithelial and tumor progenitor cells with an invasive phenotype from breast cancer patients. Int J Cancer (2010) 1.31
Effectiveness of individually tailored calendars in promoting childhood immunization in urban public health centers. Am J Public Health (2004) 1.29
Clinical significance of circulating tumor cells detected by an invasion assay in peripheral blood of patients with ovarian cancer. Gynecol Oncol (2008) 1.27
Pituitary adenylyl cyclase-activating polypeptide is an intrinsic regulator of Treg abundance and protects against experimental autoimmune encephalomyelitis. Proc Natl Acad Sci U S A (2009) 1.23
Loss of cardiac phosphoinositide 3-kinase p110 alpha results in contractile dysfunction. Circulation (2009) 1.22
Environmental cadmium and breast cancer risk. Aging (Albany NY) (2010) 1.22
New-onset asthma among soldiers serving in Iraq and Afghanistan. Allergy Asthma Proc (2010) 1.22
Noncompensation in peptide/receptor gene expression and distinct behavioral phenotypes in VIP- and PACAP-deficient mice. J Neurochem (2006) 1.21
An EM approach to MAP solution of segmenting tissue mixture percentages with application to CT-based virtual colonoscopy. Med Phys (2008) 1.19
Circadian rhythm in inhibitory synaptic transmission in the mouse suprachiasmatic nucleus. J Neurophysiol (2004) 1.18
Vasoactive intestinal peptide-null mice demonstrate enhanced sweet taste preference, dysglycemia, and reduced taste bud leptin receptor expression. Diabetes (2010) 1.16
Use of the All Patient Refined-Diagnosis Related Group (APR-DRG) Risk of Mortality Score as a Severity Adjustor in the Medical ICU. Clin Med Circ Respirat Pulm Med (2008) 1.15
Elevated expression of squamous cell carcinoma antigen (SCCA) is associated with human breast carcinoma. PLoS One (2011) 1.13
Activated G alpha q inhibits p110 alpha phosphatidylinositol 3-kinase and Akt. J Biol Chem (2003) 1.12
Pituitary adenylate cyclase-activating polypeptide and sonic hedgehog interact to control cerebellar granule precursor cell proliferation. J Neurosci (2002) 1.11
Class IA PI3K p110β subunit promotes autophagy through Rab5 small GTPase in response to growth factor limitation. Mol Cell (2013) 1.11
Lymphocyte regulation of neuropeptide gene expression after neuronal injury. J Neurosci Res (2003) 1.10
Inhibition of mammalian target of rapamycin signaling by 2-(morpholin-1-yl)pyrimido[2,1-alpha]isoquinolin-4-one. J Biol Chem (2007) 1.08
Angiogenesis is induced by airway smooth muscle strain. Am J Physiol Lung Cell Mol Physiol (2007) 1.08
A transgenic mouse model of heart failure using inducible Galpha q. J Biol Chem (2005) 1.07
Comparison of potentially preventable hospitalizations related to diabetes among Native Hawaiian, Chinese, Filipino, and Japanese elderly compared with whites, Hawai'i, December 2006-December 2010. Prev Chronic Dis (2013) 1.06
Successful surgical repair of a giant left main coronary artery aneurysm with arteriovenous fistula draining into a persistent left superior vena cava and coronary sinus: role of intraoperative transesophageal echocardiography. J Am Soc Echocardiogr (2003) 1.06
Predictors of outcome following hip fracture rehabilitation. PM R (2010) 1.06
Decreased L-type Ca2+ current in cardiac myocytes of type 1 diabetic Akita mice due to reduced phosphatidylinositol 3-kinase signaling. Diabetes (2007) 1.05
Vasoactive intestinal peptide is critical for circadian regulation of glucocorticoids. Neuroendocrinology (2008) 1.04
PI3Ks maintain the structural integrity of T-tubules in cardiac myocytes. PLoS One (2011) 1.03
Galphaq binds to p110alpha/p85alpha phosphoinositide 3-kinase and displaces Ras. Biochem J (2006) 1.03
CXCR4-mediated adhesion and MMP-9 secretion in head and neck squamous cell carcinoma. Cancer Lett (2004) 1.03
Urinary bladder function and somatic sensitivity in vasoactive intestinal polypeptide (VIP)-/- mice. J Mol Neurosci (2008) 1.02
Aristolochic acid-induced upper tract urothelial carcinoma in Taiwan: clinical characteristics and outcomes. Int J Cancer (2013) 1.00
Biomonitoring of aristolactam-DNA adducts in human tissues using ultra-performance liquid chromatography/ion-trap mass spectrometry. Chem Res Toxicol (2012) 1.00
Disruption of the PACAP gene promotes medulloblastoma in ptc1 mutant mice. Dev Biol (2007) 1.00
Galpha q inhibits cardiac L-type Ca2+ channels through phosphatidylinositol 3-kinase. J Biol Chem (2005) 0.99
Reproducibility of diabetic macular edema estimates from SD-OCT is affected by the choice of image analysis algorithm. Invest Ophthalmol Vis Sci (2013) 0.99
Antibody responses to vaccinia membrane proteins after smallpox vaccination. J Infect Dis (2007) 0.99
The relationship between body iron stores and blood and urine cadmium concentrations in US never-smoking, non-pregnant women aged 20-49 years. Environ Res (2011) 0.99
Multiple fibroelastomas: a case report and review of the literature. J Am Soc Echocardiogr (2003) 0.98
Vasoactive intestinal peptide loss leads to impaired CNS parenchymal T-cell infiltration and resistance to experimental autoimmune encephalomyelitis. Proc Natl Acad Sci U S A (2010) 0.97
Effects of vasoactive intestinal peptide genotype on circadian gene expression in the suprachiasmatic nucleus and peripheral organs. J Biol Rhythms (2011) 0.97
The role of the neuropeptides PACAP and VIP in the photic regulation of gene expression in the suprachiasmatic nucleus. Eur J Neurosci (2010) 0.97
PI3K signaling supports amphetamine-induced dopamine efflux. Biochem Biophys Res Commun (2008) 0.97
Cytochrome P450 1A2 detoxicates aristolochic acid in the mouse. Drug Metab Dispos (2010) 0.97
Extensive neoplastic cardiac infiltration in a patient with acute myelogenous leukemia: role of echocardiography. Echocardiography (2003) 0.96
Selective decreases in amphetamine self-administration and regulation of dopamine transporter function in diabetic rats. Neuroendocrinology (2003) 0.96
Deficits in social behavior and reversal learning are more prevalent in male offspring of VIP deficient female mice. Exp Neurol (2008) 0.95
Negative regulation of Hedgehog signaling by liver X receptors. Mol Endocrinol (2009) 0.93
Anabolic steroids, acute myocardial infarction and polycythemia: a case report and review of the literature. Vasc Health Risk Manag (2008) 0.93
Health benefits from large-scale ozone reduction in the United States. Environ Health Perspect (2012) 0.92
Neuropeptide mimetics and antagonists in the treatment of inflammatory disease: focus on VIP and PACAP. Curr Top Med Chem (2006) 0.92
A rare case of Listeria monocytogenes presenting as prosthetic valve bacterial endocarditis and aortic root abscess. Echocardiography (2004) 0.92
STAT3-mediated astrogliosis protects myelin development in neonatal brain injury. Ann Neurol (2012) 0.91
Increased persistent sodium current due to decreased PI3K signaling contributes to QT prolongation in the diabetic heart. Diabetes (2013) 0.91
Interaction of PACAP with Sonic hedgehog reveals complex regulation of the hedgehog pathway by PKA. Cell Signal (2013) 0.91
Phospholipase C-independent activation of glycogen synthase kinase-3beta and C-terminal Src kinase by Galphaq. J Biol Chem (2003) 0.91
Induction of colitis and rapid development of colorectal tumors in mice deficient in the neuropeptide PACAP. Int J Cancer (2008) 0.90