Published in J Neurosci on March 07, 2007
A Drosophila model for LRRK2-linked parkinsonism. Proc Natl Acad Sci U S A (2008) 2.12
Answering the ultimate question "what is the proximal cause of aging?". Aging (Albany NY) (2012) 2.04
Drosophila melanogaster in the study of human neurodegeneration. CNS Neurol Disord Drug Targets (2010) 1.33
The Drosophila vesicular monoamine transporter reduces pesticide-induced loss of dopaminergic neurons. Neurobiol Dis (2010) 1.31
Animal models of Parkinson's disease: vertebrate genetics. Cold Spring Harb Perspect Med (2012) 1.08
Genome-wide association for sensitivity to chronic oxidative stress in Drosophila melanogaster. PLoS One (2012) 1.07
The dopaminergic system in the aging brain of Drosophila. Front Neurosci (2010) 1.02
Corazonin neurons function in sexually dimorphic circuitry that shape behavioral responses to stress in Drosophila. PLoS One (2010) 0.97
Fungal-derived semiochemical 1-octen-3-ol disrupts dopamine packaging and causes neurodegeneration. Proc Natl Acad Sci U S A (2013) 0.95
The bad, the good, and the ugly about oxidative stress. Oxid Med Cell Longev (2012) 0.91
A genetic basis for the variable effect of smoking/nicotine on Parkinson's disease. Pharmacogenomics J (2012) 0.91
Dopamine dynamics and signaling in Drosophila: an overview of genes, drugs and behavioral paradigms. Exp Anim (2014) 0.90
An optimized method for histological detection of dopaminergic neurons in Drosophila melanogaster. J Histochem Cytochem (2008) 0.90
Dtorsin, the Drosophila ortholog of the early-onset dystonia TOR1A (DYT1), plays a novel role in dopamine metabolism. PLoS One (2011) 0.90
Drosophila models of Parkinson's disease: discovering relevant pathways and novel therapeutic strategies. Parkinsons Dis (2011) 0.89
Drosophila Ube3a regulates monoamine synthesis by increasing GTP cyclohydrolase I activity via a non-ubiquitin ligase mechanism. Neurobiol Dis (2010) 0.88
Heat shock protein-70 (Hsp-70) suppresses paraquat-induced neurodegeneration by inhibiting JNK and caspase-3 activation in Drosophila model of Parkinson's disease. PLoS One (2014) 0.87
Selective degeneration of dopaminergic neurons by MPP(+) and its rescue by D2 autoreceptors in Drosophila primary culture. J Neurochem (2013) 0.86
Recent advances in using Drosophila to model neurodegenerative diseases. Apoptosis (2009) 0.86
The Protective Effect of Minocycline in a Paraquat-Induced Parkinson's Disease Model in Drosophila is Modified in Altered Genetic Backgrounds. Parkinsons Dis (2012) 0.85
Catecholamines up integrates dopamine synthesis and synaptic trafficking. J Neurochem (2011) 0.85
Drosophila melanogaster as a genetic model system to study neurotransmitter transporters. Neurochem Int (2014) 0.85
A model of oxidative stress management: moderation of carbohydrate metabolizing enzymes in SOD1-null Drosophila melanogaster. PLoS One (2011) 0.83
Rotenone and paraquat perturb dopamine metabolism: A computational analysis of pesticide toxicity. Toxicology (2013) 0.83
Signaling pathways involved in 1-octen-3-ol-mediated neurotoxicity in Drosophila melanogaster: implication in Parkinson’s disease. Neurotox Res (2014) 0.83
The role of calcium channel blockers and resveratrol in the prevention of paraquat-induced parkinsonism in Drosophila melanogaster: a locomotor analysis. Invert Neurosci (2011) 0.82
The glycolytic enzyme, GPI, is a functionally conserved modifier of dopaminergic neurodegeneration in Parkinson's models. Cell Metab (2014) 0.80
A dopamine receptor contributes to paraquat-induced neurotoxicity in Drosophila. Hum Mol Genet (2014) 0.79
Invertebrate models of dystonia. Curr Neuropharmacol (2013) 0.79
Functional Characterization of Hypertrehalosemic Hormone Receptor in Relation to Hemolymph Trehalose and to Oxidative Stress in the Cockroach Blattella germanica. Front Endocrinol (Lausanne) (2012) 0.79
Perturbations in dopamine synthesis lead to discrete physiological effects and impact oxidative stress response in Drosophila. J Insect Physiol (2015) 0.78
Synergistic effects on dopamine cell death in a Drosophila model of chronic toxin exposure. Neurotoxicology (2014) 0.77
Novel whole-tissue quantitative assay of nitric oxide levels in Drosophila neuroinflammatory response. J Vis Exp (2013) 0.77
A survey of the protective effects of some commercially available antioxidant supplements in genetically and chemically induced models of oxidative stress in Drosophila melanogaster. Exp Gerontol (2012) 0.76
Lack of miRNA Misregulation at Early Pathological Stages in Drosophila Neurodegenerative Disease Models. Front Genet (2012) 0.76
Superoxide dismutase 2 knockdown leads to defects in locomotor activity, sensitivity to paraquat, and increased cuticle pigmentation in Tribolium castaneum. Sci Rep (2016) 0.75
Dmp53, basket and drICE gene knockdown and polyphenol gallic acid increase life span and locomotor activity in a Drosophila Parkinson's disease model. Genet Mol Biol (2013) 0.75
The Mitochondrial Lon Protease Is Required for Age-Specific and Sex-Specific Adaptation to Oxidative Stress. Curr Biol (2016) 0.75
Mutant human torsinA, responsible for early-onset dystonia, dominantly suppresses GTPCH expression, dopamine levels and locomotion in Drosophila melanogaster. Biol Open (2015) 0.75
Methods to characterize spontaneous and startle-induced locomotion in a rotenone-induced Parkinson's disease model of Drosophila. J Vis Exp (2014) 0.75
Paraquat-Induced Movement Disorder in Relation to Oxidative Stress-Mediated Neurodegeneration in the Brain of Drosophila melanogaster. Neurochem Res (2017) 0.75
Sex differences in oxidative stress resistance in relation to longevity in Drosophila melanogaster. J Comp Physiol B (2017) 0.75
APD2: the updated antimicrobial peptide database and its application in peptide design. Nucleic Acids Res (2008) 4.23
Detection of clinically relevant genetic variants in autism spectrum disorder by whole-genome sequencing. Am J Hum Genet (2013) 2.47
Structure of a site-2 protease family intramembrane metalloprotease. Science (2007) 2.08
c-Myc-mediated epigenetic silencing of MicroRNA-101 contributes to dysregulation of multiple pathways in hepatocellular carcinoma. Hepatology (2014) 2.04
Tracing the origin and history of HIV-1 subtype B' epidemic by near full-length genome analyses. AIDS (2012) 1.89
One-stage surgical management for thoracic tuberculosis by anterior debridement, decompression and autogenous rib grafts, and instrumentation. Spine J (2011) 1.81
Prevalence and evolution of drug resistance HIV-1 variants in Henan, China. Cell Res (2005) 1.64
RKIP sensitizes prostate and breast cancer cells to drug-induced apoptosis. J Biol Chem (2004) 1.61
Immune surveillance and therapy of lymphomas driven by Epstein-Barr virus protein LMP1 in a mouse model. Cell (2012) 1.59
Light-triggered theranostics based on photosensitizer-conjugated carbon dots for simultaneous enhanced-fluorescence imaging and photodynamic therapy. Adv Mater (2012) 1.56
Perilipin 5 improves hepatic lipotoxicity by inhibiting lipolysis. Hepatology (2015) 1.55
Bidirectional signals transduced by TOPK-ERK interaction increase tumorigenesis of HCT116 colorectal cancer cells. Gastroenterology (2007) 1.51
Photosensitizer-loaded gold vesicles with strong plasmonic coupling effect for imaging-guided photothermal/photodynamic therapy. ACS Nano (2013) 1.44
Effect of prepro-calcitonin gene-related peptide-expressing endothelial progenitor cells on pulmonary hypertension. Ann Thorac Surg (2007) 1.44
Antimicrobial activity of clove and rosemary essential oils alone and in combination. Phytother Res (2007) 1.39
Role of surgical ventricular restoration in the treatment of ischemic cardiomyopathy. Ann Thorac Surg (2013) 1.39
Superior in vivo inhibitory efficacy of methylseleninic acid against human prostate cancer over selenomethionine or selenite. Carcinogenesis (2008) 1.33
Single continuous wave laser induced photodynamic/plasmonic photothermal therapy using photosensitizer-functionalized gold nanostars. Adv Mater (2013) 1.31
MicroRNA-192 targeting retinoblastoma 1 inhibits cell proliferation and induces cell apoptosis in lung cancer cells. Nucleic Acids Res (2011) 1.30
An atlas of DNA methylomes in porcine adipose and muscle tissues. Nat Commun (2012) 1.28
Molecular signaling of the epithelial to mesenchymal transition in generating and maintaining cancer stem cells. Cell Mol Life Sci (2010) 1.27
HIV-infected former plasma donors in rural Central China: from infection to survival outcomes, 1985-2008. PLoS One (2010) 1.27
Proteomics analysis reveals novel components in the detergent-insoluble subproteome in Alzheimer's disease. J Proteome Res (2009) 1.27
Two faces of the other-race effect: recognition and categorisation of Caucasian and Chinese faces. Perception (2009) 1.21
Poly[[diaqua-hemi-μ(4)-oxalato-μ(2)-oxalato-praseodymium(III)] monohydrate]. Acta Crystallogr Sect E Struct Rep Online (2009) 1.18
HIV drug resistance and its impact on antiretroviral therapy in Chinese HIV-infected patients. PLoS One (2013) 1.16
Mesenchymal stem cell-based cell engineering with multifunctional mesoporous silica nanoparticles for tumor delivery. Biomaterials (2012) 1.13
Virologic outcomes of first-line HAART and associated factors among Chinese patients with HIV in three sentinel antiretroviral treatment sites. Trop Med Int Health (2010) 1.12
Maternal executive function, harsh parenting, and child conduct problems. J Child Psychol Psychiatry (2012) 1.12
Impact of HIV drug resistance on virologic and immunologic failure and mortality in a cohort of patients on antiretroviral therapy in China. AIDS (2013) 1.11
The crosstalk between Nrf2 and AMPK signal pathways is important for the anti-inflammatory effect of berberine in LPS-stimulated macrophages and endotoxin-shocked mice. Antioxid Redox Signal (2013) 1.09
NF-kappaB2 mutation targets TRAF1 to induce lymphomagenesis. Blood (2007) 1.07
Correction: Spatiotemporal Scan and Age-Period-Cohort Analysis of Hepatitis C Virus in Henan, China: 2005-2012. PLoS One (2015) 1.06
Cytogenetic analysis of human bone marrow-derived mesenchymal stem cells passaged in vitro. Cell Biol Int (2006) 1.06
Effects of Ougan juice on P450 activities using a cocktail method. Pharmazie (2012) 1.06
Different distribution of HIV-1 subtype and drug resistance were found among treatment naïve individuals in Henan, Guangxi, and Yunnan province of China. PLoS One (2013) 1.06
Hemivertebra resection for the treatment of congenital lumbarspinal scoliosis with lateral-posterior approach. Spine (Phila Pa 1976) (2008) 1.03
A typical N-terminal extensions confer novel regulatory properties on GTP cyclohydrolase isoforms in Drosophila melanogaster. J Biol Chem (2006) 1.02
CD133: a potential indicator for differentiation and prognosis of human cholangiocarcinoma. BMC Cancer (2011) 1.02
Protein expression profiling of the drosophila fragile X mutant brain reveals up-regulation of monoamine synthesis. Mol Cell Proteomics (2005) 1.02
Serum starvation induces H2AX phosphorylation to regulate apoptosis via p38 MAPK pathway. FEBS Lett (2008) 1.01
HIV among plasma donors and other high-risk groups in Henan, China. J Acquir Immune Defic Syndr (2010) 1.01
Regulation of smooth muscle contractility by the epithelium in rat vas deferens: role of ATP-induced release of PGE2. J Physiol (2008) 1.01
A novel class of pyranocoumarin anti-androgen receptor signaling compounds. Mol Cancer Ther (2007) 1.00
Randomized study of mononuclear bone marrow cell transplantation in patients with coronary surgery. Ann Thorac Surg (2008) 1.00
Multiple introductions of HIV into men who have sex with men were found in Zhengzhou City, China. AIDS Res Hum Retroviruses (2012) 1.00
Photosensitizer-conjugated silica-coated gold nanoclusters for fluorescence imaging-guided photodynamic therapy. Biomaterials (2013) 1.00
Activation of face expertise and the inversion effect. Psychol Sci (2006) 0.99
Culture shapes efficiency of facial age judgments. PLoS One (2010) 0.99
NF-kappaB2 is required for the control of autoimmunity by regulating the development of medullary thymic epithelial cells. J Biol Chem (2006) 0.98
Prognostic value of the D-dimer test in oesophageal cancer during the perioperative period. J Surg Oncol (2013) 0.98
An inner face advantage in children's recognition of familiar peers. J Exp Child Psychol (2008) 0.97
Mechanistic role for a novel glucocorticoid-KLF11 (TIEG2) protein pathway in stress-induced monoamine oxidase A expression. J Biol Chem (2012) 0.96
Periostin contributes to the acquisition of multipotent stem cell-like properties in human mammary epithelial cells and breast cancer cells. PLoS One (2013) 0.96
Population survey of CCR5 delta32, CCR5 m303, CCR2b 64I, and SDF1 3'A allele frequencies in indigenous Chinese healthy individuals, and in HIV-1-infected and HIV-1-uninfected individuals in HIV-1 risk groups. J Acquir Immune Defic Syndr (2003) 0.95
The C-terminal pentapeptide of Nanog tryptophan repeat domain interacts with Nac1 and regulates stem cell proliferation but not pluripotency. J Biol Chem (2009) 0.95
5-Ethynyl-2'-deoxycytidine as a new agent for DNA labeling: detection of proliferating cells. Anal Biochem (2011) 0.95
Adiponectin activates the AMPK signaling pathway to regulate lipid metabolism in bovine hepatocytes. J Steroid Biochem Mol Biol (2013) 0.94
Dye-loaded ferritin nanocages for multimodal imaging and photothermal therapy. Adv Mater (2014) 0.94
Influence of meteorological conditions and particulate matter on visual range impairment in Jinan, China. Sci Total Environ (2007) 0.93
Management of thoracic myelopathy caused by ossification of the posterior longitudinal ligament combined with ossification of the ligamentum flavum-a retrospective study. Spine J (2012) 0.92
An electrospun nanowire-based triboelectric nanogenerator and its application in a fully self-powered UV detector. Nanoscale (2014) 0.92
Decursin and decursinol angelate inhibit estrogen-stimulated and estrogen-independent growth and survival of breast cancer cells. Breast Cancer Res (2007) 0.92
Direct comparison of the potency of human mesenchymal stem cells derived from amnion tissue, bone marrow and adipose tissue at inducing dermal fibroblast responses to cutaneous wounds. Int J Mol Med (2012) 0.92
RNA editing of hepatitis B virus transcripts by activation-induced cytidine deaminase. Proc Natl Acad Sci U S A (2013) 0.92
BAL1 and its partner E3 ligase, BBAP, link Poly(ADP-ribose) activation, ubiquitylation, and double-strand DNA repair independent of ATM, MDC1, and RNF8. Mol Cell Biol (2012) 0.92
Drosophila dopamine synthesis pathway genes regulate tracheal morphogenesis. Dev Biol (2007) 0.92
Correlation between composition of the bacterial community and concentration of volatile fatty acids in the rumen during the transition period and ketosis in dairy cows. Appl Environ Microbiol (2012) 0.91
Experimental characterization of a 400 Gbit/s orbital angular momentum multiplexed free-space optical link over 120 m. Opt Lett (2016) 0.91
Human immunodeficiency virus type 1 subtypes prevalence in central China. Yonsei Med J (2009) 0.91
Amyloid-β protein (Aβ) Glu11 is the major β-secretase site of β-site amyloid-β precursor protein-cleaving enzyme 1(BACE1), and shifting the cleavage site to Aβ Asp1 contributes to Alzheimer pathogenesis. Eur J Neurosci (2013) 0.91
MiR-490-3p modulates the proliferation of vascular smooth muscle cells induced by ox-LDL through targeting PAPP-A. Cardiovasc Res (2013) 0.91
Preparation and identification of monoclonal antibody against abrin-a. J Agric Food Chem (2011) 0.90
Free-space optical communications using orbital-angular-momentum multiplexing combined with MIMO-based spatial multiplexing. Opt Lett (2015) 0.90
Cardiac myxoma and myxosarcoma: clinical experience and immunohistochemistry. Asian Cardiovasc Thorac Ann (2002) 0.90
Dtorsin, the Drosophila ortholog of the early-onset dystonia TOR1A (DYT1), plays a novel role in dopamine metabolism. PLoS One (2011) 0.90
Approach/positive anticipation, frustration/anger, and overt aggression in childhood. J Pers (2010) 0.90
Role of the DSC1 channel in regulating neuronal excitability in Drosophila melanogaster: extending nervous system stability under stress. PLoS Genet (2013) 0.90
A colloidal gold probe-based silver enhancement immunochromatographic assay for the rapid detection of abrin-a. Biosens Bioelectron (2011) 0.90
A cyclic HSV1-TK reporter for real-time PET imaging of apoptosis. Proc Natl Acad Sci U S A (2014) 0.89
Diagnosis and surgical management of intraspinal hemorrhagic juxtafacet cysts in lumbar spine: experience of eight cases. Neurol India (2010) 0.89
pH-sensitive fluorescent dyes: are they really pH-sensitive in cells? Mol Pharm (2013) 0.89
Uracil DNA glycosylase counteracts APOBEC3G-induced hypermutation of hepatitis B viral genomes: excision repair of covalently closed circular DNA. PLoS Pathog (2013) 0.89
Graphene magnetoresistance device in van der Pauw geometry. Nano Lett (2011) 0.89
Inflammatory pseudotumor-like follicular dendritic cell tumor of liver and spleen: granulomatous and eosinophil-rich variants mimicking inflammatory or infective lesions. Am J Surg Pathol (2014) 0.88
Plasma miRNA levels correlate with sensitivity to bone mineral density in postmenopausal osteoporosis patients. Biomarkers (2014) 0.88
Influence of neoadjuvant chemotherapy on HER2/neu status in invasive breast cancer. Clin Breast Cancer (2012) 0.88
Chimeric 5/35 adenovirus-mediated Dickkopf-1 overexpression suppressed tumorigenicity of CD44⁺ gastric cancer cells via attenuating Wnt signaling. J Gastroenterol (2012) 0.88
[The prevalence of HIV-1 drug resistance and associated factors in AIDS patients receiving HAART in Zhecheng county, Henan province]. Zhonghua Yu Fang Yi Xue Za Zhi (2011) 0.88
Drosophila Ube3a regulates monoamine synthesis by increasing GTP cyclohydrolase I activity via a non-ubiquitin ligase mechanism. Neurobiol Dis (2010) 0.88
Single-stage posterior debridement and transforaminal lumbar interbody fusion with autogenous bone grafting and posterior instrumentation in the surgical management of lumbar tuberculosis. Arch Orthop Trauma Surg (2010) 0.87
Isolation and identification of the phenolic compounds from the roots of Sanguisorba officinalis L. and their antioxidant activities. Molecules (2012) 0.87
Fluorescent nanogel of arsenic sulfide nanoclusters. Angew Chem Int Ed Engl (2009) 0.87
Coexistence of aneurysmal subarachnoid hemorrhage and surgically identified pituitary apoplexy: a case report and review of the literature. J Med Case Rep (2014) 0.87
MICA/B expression is inhibited by unfolded protein response and associated with poor prognosis in human hepatocellular carcinoma. J Exp Clin Cancer Res (2014) 0.87
Direct binding of GTP cyclohydrolase and tyrosine hydroxylase: regulatory interactions between key enzymes in dopamine biosynthesis. J Biol Chem (2008) 0.87
Immortalization of normal human cytotrophoblast cells by reconstitution of telomeric reverse transcriptase activity. Mol Hum Reprod (2006) 0.87
PIK3CA and AKT gene polymorphisms in susceptibility to osteosarcoma in a Chinese population. Asian Pac J Cancer Prev (2013) 0.86
Efficient fluorescence resonance energy transfer between upconversion nanophosphors and graphene oxide: a highly sensitive biosensing platform. Chem Commun (Camb) (2011) 0.86
Inhibition of MAPK-mediated ACE expression by compound C66 prevents STZ-induced diabetic nephropathy. J Cell Mol Med (2013) 0.86