PubRank

Iris Behrmann

Author PubWeight™ 49.39‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Principles of interleukin (IL)-6-type cytokine signalling and its regulation. Biochem J 2003 10.77
2 Jak1 has a dominant role over Jak3 in signal transduction through γc-containing cytokine receptors. Chem Biol 2011 2.05
3 Signatures of microRNAs and selected microRNA target genes in human melanoma. Cancer Res 2010 1.90
4 Jaks and cytokine receptors--an intimate relationship. Biochem Pharmacol 2006 1.50
5 A cost effective non-commercial ECL-solution for Western blot detections yielding strong signals and low background. J Immunol Methods 2006 1.50
6 SHP2 and SOCS3 contribute to Tyr-759-dependent attenuation of interleukin-6 signaling through gp130. J Biol Chem 2002 1.48
7 Perspectives for the use of structural information and chemical genetics to develop inhibitors of Janus kinases. J Cell Mol Med 2010 1.19
8 Cross-regulation of cytokine signalling: pro-inflammatory cytokines restrict IL-6 signalling through receptor internalisation and degradation. J Cell Sci 2010 1.17
9 Identification of the critical sequence elements in the cytoplasmic domain of leptin receptor isoforms required for Janus kinase/signal transducer and activator of transcription activation by receptor heterodimers. Mol Endocrinol 2002 1.16
10 The Jak1 SH2 domain does not fulfill a classical SH2 function in Jak/STAT signaling but plays a structural role for receptor interaction and up-regulation of receptor surface expression. J Biol Chem 2005 1.10
11 Long term association of the cytokine receptor gp130 and the Janus kinase Jak1 revealed by FRAP analysis. J Biol Chem 2003 1.10
12 Promoter-hypermethylation is causing functional relevant downregulation of methylthioadenosine phosphorylase (MTAP) expression in hepatocellular carcinoma. Carcinogenesis 2005 1.09
13 The matrix metalloproteinase 9 (mmp-9) hemopexin domain is a novel gelatin binding domain and acts as an antagonist. J Biol Chem 2002 1.08
14 New target genes of MITF-induced microRNA-211 contribute to melanoma cell invasion. PLoS One 2013 1.06
15 Akt modulates STAT3-mediated gene expression through a FKHR (FOXO1a)-dependent mechanism. J Biol Chem 2002 1.04
16 Cell density dependent increase of constitutive signal transducers and activators of transcription 3 activity in melanoma cells is mediated by Janus kinases. Mol Cancer Res 2007 1.02
17 Novel role of Janus kinase 1 in the regulation of oncostatin M receptor surface expression. J Biol Chem 2002 1.01
18 Interferon-γ-induced activation of Signal Transducer and Activator of Transcription 1 (STAT1) up-regulates the tumor suppressing microRNA-29 family in melanoma cells. Cell Commun Signal 2012 1.00
19 The role of the inhibitors of interleukin-6 signal transduction SHP2 and SOCS3 for desensitization of interleukin-6 signalling. Biochem J 2004 0.98
20 Multiple reasons for an inefficient STAT1 response upon IL-6-type cytokine stimulation. Cell Signal 2005 0.97
21 Orientational constraints of the gp130 intracellular juxtamembrane domain for signaling. J Biol Chem 2002 0.97
22 STAT5 contributes to interferon resistance of melanoma cells. Curr Biol 2005 0.96
23 Hypoxia-inducible factor 1alpha is up-regulated by oncostatin M and participates in oncostatin M signaling. Hepatology 2009 0.96
24 Dual role of the Jak1 FERM and kinase domains in cytokine receptor binding and in stimulation-dependent Jak activation. J Immunol 2008 0.95
25 Are STATS arginine-methylated? J Biol Chem 2005 0.95
26 Interferon-gamma-mediated growth regulation of melanoma cells: involvement of STAT1-dependent and STAT1-independent signals. J Invest Dermatol 2004 0.95
27 Dynamic regulation of microRNA expression following interferon-γ-induced gene transcription. RNA Biol 2012 0.93
28 JAK2 mutants (e.g., JAK2V617F) and their importance as drug targets in myeloproliferative neoplasms. JAKSTAT 2013 0.91
29 Structural requirements of the interleukin-6 signal transducer gp130 for its interaction with Janus kinase 1: the receptor is crucial for kinase activation. Biochem J 2002 0.89
30 STAT1 regulates p73-mediated Bax gene expression. FEBS Lett 2007 0.88
31 Recombinant interleukin-24 lacks apoptosis-inducing properties in melanoma cells. PLoS One 2007 0.87
32 An unusual insertion in Jak2 is crucial for kinase activity and differentially affects cytokine responses. J Immunol 2009 0.85
33 Constitutive suppressor of cytokine signaling 3 expression confers a growth advantage to a human melanoma cell line. Mol Cancer Res 2007 0.84
34 Three dileucine-like motifs within the interbox1/2 region of the human oncostatin M receptor prevent efficient surface expression in the absence of an associated Janus kinase. J Biol Chem 2005 0.82
35 Cooperative effects of Janus and Aurora kinase inhibition by CEP701 in cells expressing Jak2V617F. J Cell Mol Med 2013 0.82
36 Oncostatin M up-regulates the ER chaperone Grp78/BiP in liver cells. Biochem Pharmacol 2010 0.81
37 JAK2-V617F-induced MAPK activity is regulated by PI3K and acts synergistically with PI3K on the proliferation of JAK2-V617F-positive cells. JAKSTAT 2013 0.76
38 Signal transduction, receptors, mediators and genes: younger than ever - the 13th meeting of the Signal Transduction Society focused on aging and immunology. Cell Commun Signal 2010 0.76