|
1
|
Downregulation of microRNA expression in the lungs of rats exposed to cigarette smoke.
|
FASEB J
|
2008
|
2.58
|
|
2
|
In situ detection of neoplastic transformation and chemopreventive effects in rat esophagus epithelium using angle-resolved low-coherence interferometry.
|
Cancer Res
|
2003
|
1.78
|
|
3
|
Prospective grading of neoplastic change in rat esophagus epithelium using angle-resolved low-coherence interferometry.
|
J Biomed Opt
|
2005
|
1.56
|
|
4
|
In situ assessment of intraepithelial neoplasia in hamster trachea epithelium using angle-resolved low-coherence interferometry.
|
Cancer Epidemiol Biomarkers Prev
|
2007
|
1.45
|
|
5
|
Preventive effects of NSAIDs, NO-NSAIDs, and NSAIDs plus difluoromethylornithine in a chemically induced urinary bladder cancer model.
|
Cancer Prev Res (Phila)
|
2013
|
1.45
|
|
6
|
Targeting the AKT protein kinase for cancer chemoprevention.
|
Mol Cancer Ther
|
2007
|
1.45
|
|
7
|
Chemoprevention of familial adenomatous polyposis by low doses of atorvastatin and celecoxib given individually and in combination to APCMin mice.
|
Cancer Res
|
2006
|
1.43
|
|
8
|
Rosiglitazone, a PPAR gamma agonist: potent promoter of hydroxybutyl(butyl)nitrosamine-induced urinary bladder cancers.
|
Int J Cancer
|
2008
|
1.34
|
|
9
|
Relationships of microRNA expression in mouse lung with age and exposure to cigarette smoke and light.
|
FASEB J
|
2009
|
1.31
|
|
10
|
The epidermal growth factor receptor inhibitor gefitinib prevents the progression of pancreatic lesions to carcinoma in a conditional LSL-KrasG12D/+ transgenic mouse model.
|
Cancer Prev Res (Phila)
|
2010
|
1.28
|
|
11
|
Prevention of azoxymethane-induced colon cancer by combination of low doses of atorvastatin, aspirin, and celecoxib in F 344 rats.
|
Cancer Res
|
2006
|
1.19
|
|
12
|
Is inducible nitric oxide synthase a target for chemoprevention?
|
Mol Cancer Ther
|
2003
|
1.19
|
|
13
|
Potent carcinogenicity of cigarette smoke in mice exposed early in life.
|
Carcinogenesis
|
2007
|
1.17
|
|
14
|
Atorvastatin delays progression of pancreatic lesions to carcinoma by regulating PI3/AKT signaling in p48Cre/+ LSL-KrasG12D/+ mice.
|
Int J Cancer
|
2012
|
1.15
|
|
15
|
Nitric oxide-releasing aspirin and indomethacin are potent inhibitors against colon cancer in azoxymethane-treated rats: effects on molecular targets.
|
Mol Cancer Ther
|
2006
|
1.15
|
|
16
|
Chemoprevention of cigarette smoke-induced alterations of MicroRNA expression in rat lungs.
|
Cancer Prev Res (Phila)
|
2010
|
1.13
|
|
17
|
Modulation of microRNA expression by budesonide, phenethyl isothiocyanate and cigarette smoke in mouse liver and lung.
|
Carcinogenesis
|
2010
|
1.08
|
|
18
|
Chemoprevention of colon and small intestinal tumorigenesis in APC(Min/+) mice by licofelone, a novel dual 5-LOX/COX inhibitor: potential implications for human colon cancer prevention.
|
Cancer Prev Res (Phila)
|
2011
|
1.04
|
|
19
|
Inhibition of azoxymethane-induced colorectal cancer by CP-31398, a TP53 modulator, alone or in combination with low doses of celecoxib in male F344 rats.
|
Cancer Res
|
2009
|
1.03
|
|
20
|
Prevention of mouse lung tumors by budesonide and its modulation of biomarkers.
|
Carcinogenesis
|
2002
|
1.03
|
|
21
|
Chemoprevention of rat prostate carcinogenesis by soy isoflavones and by Bowman-Birk inhibitor.
|
Nutr Cancer
|
2007
|
1.01
|
|
22
|
Chemopreventive effects of Frondanol A5, a Cucumaria frondosa extract, against rat colon carcinogenesis and inhibition of human colon cancer cell growth.
|
Cancer Prev Res (Phila)
|
2010
|
1.01
|
|
23
|
Null activity of selenium and vitamin e as cancer chemopreventive agents in the rat prostate.
|
Cancer Prev Res (Phila)
|
2010
|
0.99
|
|
24
|
Dose-responsiveness and persistence of microRNA expression alterations induced by cigarette smoke in mouse lung.
|
Mutat Res
|
2010
|
0.99
|
|
25
|
Chemopreventive effects of RXR-selective rexinoid bexarotene on intestinal neoplasia of Apc(Min/+) mice.
|
Neoplasia
|
2012
|
0.98
|
|
26
|
Overexpression of cyclooxygenase-2 in rat oral cancers and prevention of oral carcinogenesis in rats by selective and nonselective COX inhibitors.
|
Cancer Prev Res (Phila)
|
2010
|
0.98
|
|
27
|
Inhibition of pancreatic intraepithelial neoplasia progression to carcinoma by nitric oxide-releasing aspirin in p48(Cre/+)-LSL-Kras(G12D/+) mice.
|
Neoplasia
|
2012
|
0.97
|
|
28
|
Chemoprevention by lipoxygenase and leukotriene pathway inhibitors of vinyl carbamate-induced lung tumors in mice.
|
Cancer Res
|
2002
|
0.96
|
|
29
|
Chemoprevention of rat prostate carcinogenesis by dietary 16alpha-fluoro-5-androsten-17-one (fluasterone), a minimally androgenic analog of dehydroepiandrosterone.
|
Carcinogenesis
|
2006
|
0.95
|
|
30
|
Smoke-induced microRNA and related proteome alterations. Modulation by chemopreventive agents.
|
Int J Cancer
|
2012
|
0.95
|
|
31
|
Estrogen receptor-beta as a potential target for colon cancer prevention: chemoprevention of azoxymethane-induced colon carcinogenesis by raloxifene in F344 rats.
|
Cancer Prev Res (Phila)
|
2009
|
0.94
|
|
32
|
Prevention of cigarette smoke-induced lung tumors in mice by budesonide, phenethyl isothiocyanate, and N-acetylcysteine.
|
Int J Cancer
|
2010
|
0.93
|
|
33
|
Lack of efficacy of the statins atorvastatin and lovastatin in rodent mammary carcinogenesis.
|
Cancer Prev Res (Phila)
|
2009
|
0.92
|
|
34
|
Characterization of rat ovarian adenocarcinomas developed in response to direct instillation of 7,12-dimethylbenz[a]anthracene (DMBA) coated suture.
|
Carcinogenesis
|
2005
|
0.92
|
|
35
|
Neu-induced retroviral rat mammary carcinogenesis: a novel chemoprevention model for both hormonally responsive and nonresponsive mammary carcinomas.
|
Cancer Res
|
2006
|
0.91
|
|
36
|
S-adenosyl L-methionine inhibits azoxymethane-induced colonic aberrant crypt foci in F344 rats and suppresses human colon cancer Caco-2 cell growth in 3D culture.
|
Int J Cancer
|
2008
|
0.91
|
|
37
|
Interplay between histopathological alterations, cigarette smoke and chemopreventive agents in defining microRNA profiles in mouse lung.
|
Mutat Res
|
2010
|
0.91
|
|
38
|
Differential carcinogenicity of cigarette smoke in mice exposed either transplacentally, early in life or in adulthood.
|
Int J Cancer
|
2011
|
0.90
|
|
39
|
Prenatal N-acetylcysteine prevents cigarette smoke-induced lung cancer in neonatal mice.
|
Carcinogenesis
|
2009
|
0.89
|
|
40
|
Retinoid receptor-dependent and independent biological activities of novel fenretinide analogues and metabolites.
|
Clin Cancer Res
|
2003
|
0.89
|
|
41
|
Exposure of mice to cigarette smoke and/or light causes DNA alterations in heart and aorta.
|
Mutat Res
|
2008
|
0.89
|
|
42
|
High susceptibility of neonatal mice to molecular, biochemical and cytogenetic alterations induced by environmental cigarette smoke and light.
|
Mutat Res
|
2007
|
0.89
|
|
43
|
Preneoplastic and neoplastic lesions in the lung, liver and urinary tract of mice exposed to environmental cigarette smoke and UV light since birth.
|
Int J Cancer
|
2008
|
0.88
|
|
44
|
Piroxicam selectively inhibits the growth of premalignant and malignant human oral cell lines by limiting their progression through the S phase and reducing the levels of cyclins and AP-1.
|
Int J Cancer
|
2003
|
0.88
|
|
45
|
Screening agents for preventive efficacy in a bladder cancer model: study design, end points, and gefitinib and naproxen efficacy.
|
J Urol
|
2010
|
0.88
|
|
46
|
Modulation by celecoxib and difluoromethylornithine of the methylation of DNA and the estrogen receptor-alpha gene in rat colon tumors.
|
Carcinogenesis
|
2004
|
0.87
|
|
47
|
Preventive effects of polyphenon E on urinary bladder and mammary cancers in rats and correlations with serum and urine levels of tea polyphenols.
|
Mol Cancer Ther
|
2007
|
0.87
|
|
48
|
4-Hydroxybutyl(butyl)nitrosamine-induced urinary bladder cancers in mice: characterization of FHIT and survivin expression and chemopreventive effects of indomethacin.
|
Carcinogenesis
|
2004
|
0.86
|
|
49
|
Effects of 5,6-benzoflavone, indole-3-carbinol (I3C) and diindolylmethane (DIM) on chemically-induced mammary carcinogenesis: is DIM a substitute for I3C?
|
Oncol Rep
|
2011
|
0.86
|
|
50
|
Cigarette smoke induces DNA damage and alters base-excision repair and tau levels in the brain of neonatal mice.
|
Toxicol Sci
|
2011
|
0.86
|
|
51
|
Prevention of mouse lung tumors by targretin.
|
Int J Cancer
|
2006
|
0.86
|
|
52
|
Altered expression of c-myc, p16 and p27 in rat colon tumors and its reversal by short-term treatment with chemopreventive agents.
|
Carcinogenesis
|
2002
|
0.86
|
|
53
|
MicroRNAs as targets for dietary and pharmacological inhibitors of mutagenesis and carcinogenesis.
|
Mutat Res
|
2012
|
0.85
|
|
54
|
N-(4-Hydroxyphenyl)retinamide is more potent than other phenylretinamides in inhibiting the growth of BRCA1-mutated breast cancer cells.
|
Carcinogenesis
|
2005
|
0.85
|
|
55
|
Low doses of beta-carotene and lutein inhibit AOM-induced rat colonic ACF formation but high doses augment ACF incidence.
|
Int J Cancer
|
2005
|
0.85
|
|
56
|
Inhibition of lung tumor development by berry extracts in mice exposed to cigarette smoke.
|
Int J Cancer
|
2012
|
0.85
|
|
57
|
Modulation by phenethyl isothiocyanate and budesonide of molecular and histopathologic alterations induced by environmental cigarette smoke in mice.
|
Cancer Prev Res (Phila)
|
2009
|
0.84
|
|
58
|
Effects of the farnesyl transferase inhibitor R115777 (Zarnestra) on mammary carcinogenesis: prevention, therapy, and role of HaRas mutations.
|
Mol Cancer Ther
|
2006
|
0.84
|
|
59
|
AKT and the phosphatidylinositol 3-kinase/AKT pathway: important molecular targets for lung cancer prevention and treatment.
|
J Natl Cancer Inst
|
2003
|
0.84
|
|
60
|
Efficacy of Targretin on methylnitrosourea-induced mammary cancers: prevention and therapy dose-response curves and effects on proliferation and apoptosis.
|
Carcinogenesis
|
2004
|
0.84
|
|
61
|
Upregulation of stem cell antigen-1 in the lung of neonatal mice exposed to environmental cigarette smoke.
|
Oncol Rep
|
2009
|
0.83
|
|
62
|
The chemopreventive efficacy of inhaled oltipraz particulates in the B[a]P-induced A/J mouse lung adenoma model.
|
Carcinogenesis
|
2006
|
0.83
|
|
63
|
Effects of gefitinib (Iressa) on mammary cancers: preventive studies with varied dosages, combinations with vorozole or targretin, and biomarker changes.
|
Mol Cancer Ther
|
2008
|
0.83
|
|
64
|
Chemoprevention of benzo(a)pyrene-induced lung tumors in mice by the farnesyltransferase inhibitor R115777.
|
Clin Cancer Res
|
2003
|
0.82
|
|
65
|
Null effect of dietary restriction on prostate carcinogenesis in the Wistar-Unilever rat.
|
Nutr Cancer
|
2007
|
0.82
|
|
66
|
Relationships between pulmonary micro-RNA and proteome profiles, systemic cytogenetic damage and lung tumors in cigarette smoke-exposed mice treated with chemopreventive agents.
|
Carcinogenesis
|
2013
|
0.82
|
|
67
|
9-cis-retinoic acid but not 4-(hydroxyphenyl)retinamide inhibits prostate intraepithelial neoplasia in Noble rats.
|
Cancer Res
|
2002
|
0.82
|
|
68
|
Early-phase development of cancer prevention agents: challenges and opportunities.
|
Cancer Prev Res (Phila)
|
2013
|
0.82
|
|
69
|
Modulation by bexarotene of mRNA expression of genes in mouse lung tumors.
|
Mol Carcinog
|
2008
|
0.81
|
|
70
|
Retracted
Prevention of mouse lung tumors and modulation of DNA methylation by combined treatment with budesonide and R115777 (Zarnestra MT).
|
Carcinogenesis
|
2006
|
0.81
|
|
71
|
Modulation by budesonide of DNA methylation and mRNA expression in mouse lung tumors.
|
Int J Cancer
|
2007
|
0.81
|
|
72
|
Oxidative stress in the lung of mice exposed to cigarette smoke either early in life or in adulthood.
|
Arch Toxicol
|
2013
|
0.81
|
|
73
|
Chemopreventive efficacy and mechanism of licofelone in a mouse lung tumor model via aspiration.
|
Cancer Prev Res (Phila)
|
2011
|
0.81
|
|
74
|
Chemoprevention of colon carcinogenesis by oleanolic acid and its analog in male F344 rats and modulation of COX-2 and apoptosis in human colon HT-29 cancer cells.
|
Pharm Res
|
2008
|
0.80
|
|
75
|
Modulation by metformin of molecular and histopathological alterations in the lung of cigarette smoke-exposed mice.
|
Cancer Med
|
2014
|
0.80
|
|
76
|
DNA damage in exfoliated cells and histopathological alterations in the urinary tract of mice exposed to cigarette smoke and treated with chemopreventive agents.
|
Carcinogenesis
|
2012
|
0.80
|
|
77
|
Modulation of DNA hypomethylation as a surrogate endpoint biomarker for chemoprevention of colon cancer.
|
Mol Carcinog
|
2004
|
0.80
|
|
78
|
Multitargeted low-dose GLAD combination chemoprevention: a novel and promising approach to combat colon carcinogenesis.
|
Neoplasia
|
2013
|
0.80
|
|
79
|
Beta-ionone inhibits colonic aberrant crypt foci formation in rats, suppresses cell growth, and induces retinoid X receptor-alpha in human colon cancer cells.
|
Mol Cancer Ther
|
2008
|
0.80
|
|
80
|
The human epithelial cell cytotoxicity assay for determining tissue specific toxicity: method modifications.
|
Methods Cell Sci
|
2002
|
0.79
|
|
81
|
Efficacy of the EGFr inhibitor Iressa on development of chemically-induced urinary bladder cancers: dose dependency and modulation of biomarkers.
|
Oncol Rep
|
2011
|
0.79
|
|
82
|
Development and characteristics of a human cell assay for screening agents for melanoma prevention.
|
Melanoma Res
|
2007
|
0.79
|
|
83
|
Effect of budesonide on the methylation and mRNA expression of the insulin-like growth factor 2 and c-myc genes in mouse lung tumors.
|
Mol Carcinog
|
2002
|
0.79
|
|
84
|
Differential activity of NO synthase inhibitors as chemopreventive agents in a primary rat tracheal epithelial cell transformation system.
|
Neoplasia
|
2002
|
0.79
|
|
85
|
Anti-carcinogenic properties of omeprazole against human colon cancer cells and azoxymethane-induced colonic aberrant crypt foci formation in rats.
|
Int J Oncol
|
2011
|
0.78
|
|
86
|
Dose-related cytogenetic damage in pulmonary alveolar macrophages from mice exposed to cigarette smoke early in life.
|
Arch Toxicol
|
2011
|
0.78
|
|
87
|
Prevention of methylnitrosourea-induced mammary cancers by 9-cis-retinoic acid and/or vitamin D3.
|
Oncol Rep
|
2002
|
0.78
|
|
88
|
Efficacy of chemopreventive agents in mouse mammary gland organ culture (MMOC) model: a comprehensive review.
|
Curr Med Chem
|
2008
|
0.78
|
|
89
|
Pharmacokinetic and pharmacodynamic study of NO-donating aspirin in F344 rats.
|
Int J Oncol
|
2008
|
0.78
|
|
90
|
Modulation by budesonide of a CpG endonuclease in mouse lung tumors.
|
Carcinogenesis
|
2007
|
0.77
|
|
91
|
Chemopreventive efficacy of raloxifene, bexarotene, and their combination on the progression of chemically induced colon adenomas to adenocarcinomas in rats.
|
Cancer Prev Res (Phila)
|
2013
|
0.77
|
|
92
|
Chemopreventive efficacy of Targretin in rodent models of urinary bladder, colon/intestine, head and neck and mammary cancers.
|
Oncol Rep
|
2012
|
0.77
|
|
93
|
Efficacy of 9-cis-retinoic acid and N-(4-hydroxyphenyl) retinamide alone and in combination in mammary cancer prevention.
|
Oncol Rep
|
2004
|
0.77
|
|
94
|
Chemopreventive effects of an HDAC2-selective inhibitor on rat colon carcinogenesis and APCmin/+ mouse intestinal tumorigenesis.
|
J Pharmacol Exp Ther
|
2013
|
0.77
|
|
95
|
Prevention of mouse lung tumors and modulation of DNA methylation by combined treatment with budesonide and R115777 (ZarnestraMT).
|
Carcinogenesis
|
2006
|
0.77
|
|
96
|
Quantitative morphometry of respiratory tract epithelial cells as a tool for testing chemopreventive agent efficacy.
|
Anticancer Res
|
2010
|
0.76
|
|
97
|
Modulation by licofelone and celecoxib of experimentally induced cancer and preneoplastic lesions in mice exposed to cigarette smoke.
|
Curr Cancer Drug Targets
|
2015
|
0.76
|
|
98
|
Rationale and approaches to the prevention of smoking-related diseases: overview of recent studies on chemoprevention of smoking-induced tumors in rodent models.
|
J Environ Sci Health C Environ Carcinog Ecotoxicol Rev
|
2014
|
0.76
|
|
99
|
Chemoprevention of mouse lung and colon tumors by suberoylanilide hydroxamic acid and atorvastatin.
|
Int J Cancer
|
2012
|
0.76
|
|
100
|
Correlation of in vitro chemopreventive efficacy data from the human epidermal cell assay with animal efficacy data and clinical trial plasma levels.
|
J Cell Biochem
|
2005
|
0.76
|
|
101
|
Effect of intermittent dosing regimens of erlotinib on methylnitrosourea-induced mammary carcinogenesis.
|
Cancer Prev Res (Phila)
|
2013
|
0.76
|
|
102
|
Pancreatic Cancer Chemoprevention Translational Workshop: Meeting Report.
|
Pancreas
|
2016
|
0.75
|
|
103
|
Budesonide and phenethyl isothiocyanate attenuate DNA damage in bronchoalveolar lavage cells of mice exposed to environmental cigarette smoke.
|
Curr Cancer Drug Targets
|
2008
|
0.75
|
|
104
|
Bandaru s. Reddy: in memoriam (1930-2009).
|
Cancer Prev Res (Phila)
|
2009
|
0.75
|
|
105
|
Effects of body weight gain reduction resulting from chemopreventive agent treatment on mammary gland morphology.
|
Nutr Cancer
|
2002
|
0.75
|
|
106
|
Toxicity profile of solvents by aspiration approach for topical agent delivery to respiratory tract epithelium.
|
Int J Toxicol
|
2011
|
0.75
|
|
107
|
Induction of apoptosis by 1,4-phenylenebis(methylene)selenocyanate in cultured human colon cancer cells.
|
Anticancer Res
|
2002
|
0.75
|
|
108
|
Prevention of familial adenomatous polyp development in APC min mice and azoxymethane-induced colon carcinogenesis in F344 Rats by ω-3 fatty acid rich perilla oil.
|
Nutr Cancer
|
2013
|
0.75
|