PubRank

P J Rosenthal

Author PubWeight™ 42.68‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Difficulties in the prevention, diagnosis, and treatment of imported malaria. Arch Intern Med 2000 2.17
2 Characterization of native and recombinant falcipain-2, a principal trophozoite cysteine protease and essential hemoglobinase of Plasmodium falciparum. J Biol Chem 2000 2.16
3 Expression and characterization of the Plasmodium falciparum haemoglobinase falcipain-3. Biochem J 2001 2.00
4 The proteases and pathogenicity of parasitic protozoa. Annu Rev Microbiol 1993 1.96
5 Population pharmacokinetics and pharmacodynamics of piperaquine in children with uncomplicated falciparum malaria. Clin Pharmacol Ther 2012 1.87
6 Structure-based inhibitor design by using protein models for the development of antiparasitic agents. Proc Natl Acad Sci U S A 1993 1.82
7 Polymorphisms in the Plasmodium falciparum pfcrt and pfmdr-1 genes and clinical response to chloroquine in Kampala, Uganda. J Infect Dis 2001 1.75
8 Killing of Neisseria meningitidis by human neutrophils: implications for normal and complement-deficient individuals. J Infect Dis 1987 1.65
9 Amodiaquine, sulfadoxine/pyrimethamine, and combination therapy for treatment of uncomplicated falciparum malaria in Kampala, Uganda: a randomised trial. Lancet 2001 1.58
10 The comparative efficacy of chloroquine and sulfadoxine-pyrimethamine for the treatment of uncomplicated falciparum malaria in Kampala, Uganda. Trans R Soc Trop Med Hyg 2001 1.45
11 Comparison of efficacies of cysteine protease inhibitors against five strains of Plasmodium falciparum. Antimicrob Agents Chemother 2001 1.40
12 Amodiaquine metabolism is impaired by common polymorphisms in CYP2C8: implications for malaria treatment in Africa. Clin Pharmacol Ther 2007 1.39
13 Antimalarial effects in mice of orally administered peptidyl cysteine protease inhibitors. Bioorg Med Chem 1999 1.34
14 Systematic optimization of expression and refolding of the Plasmodium falciparum cysteine protease falcipain-2. Protein Expr Purif 2001 1.32
15 Identification of three stage-specific proteinases of Plasmodium falciparum. J Exp Med 1987 1.30
16 Synthesis of quinolinyl chalcones and evaluation of their antimalarial activity. Eur J Med Chem 2001 1.28
17 Antimalarial synergy of cysteine and aspartic protease inhibitors. Antimicrob Agents Chemother 1998 1.27
18 Functional expression of falcipain, a Plasmodium falciparum cysteine proteinase, supports its role as a malarial hemoglobinase. Infect Immun 1995 1.17
19 Predictors of chloroquine treatment failure in children and adults with falciparum malaria in Kampala, Uganda. Am J Trop Med Hyg 2000 1.17
20 Structure-based design, synthesis and evaluation of conformationally constrained cysteine protease inhibitors. Bioorg Med Chem 1998 1.10
21 Recombinant falcipain-2 cleaves erythrocyte membrane ankyrin and protein 4.1. Mol Biochem Parasitol 2001 1.09
22 Cysteine proteinase inhibitors block early steps in hemoglobin degradation by cultured malaria parasites. Blood 1996 0.96
23 Light effects in yeast: persisting oscillations in cell division activity and amino acid transport in cultures of Saccharomyces cerevisiae entrained by light-dark cycles. Photochem Photobiol 1979 0.92
24 Plasmodial serine repeat antigen homologues with properties of schizont cysteine proteases. Mol Biochem Parasitol 1998 0.88
25 Intermittent preventive therapy for malaria in pregnancy: is sulfadoxine-pyrimethamine the right drug? Clin Pharmacol Ther 2010 0.87
26 The impact of whole genome sequence data on drug discovery--a malaria case study. Mol Med 2001 0.87
27 Antiprotozoal activities of some constituents of Markhamia tomentosa (Bignoniaceae). Ann Trop Med Parasitol 2010 0.87
28 Anti-malarial drug development using models of enzyme structure. Chem Biol 1994 0.84
29 Synthesis and antimalarial effects of phenothiazine inhibitors of a Plasmodium falciparum cysteine protease. J Med Chem 1997 0.82
30 Light effects in yeast: evidence for participation of cytochromes in photoinhibition of growth and transport in Saccharomyces cerevisiae cultured at low temperatures. J Bacteriol 1979 0.81
31 Drug overdoses with antimalarial agents: prescribing and dispensing errors. JAMA 1998 0.78
32 Availability of intravenous quinidine for falciparum malaria. N Engl J Med 1996 0.77
33 Protective immune responses against protease-like antigens of the murine malaria parasite Plasmodium vinckei. Vaccine 1998 0.77
34 Malaria in a Trinidadian man. N Engl J Med 2000 0.75
35 Humoral immune responses of Africans to cysteine protease-related antigens of Plasmodium falciparum. J Infect Dis 1998 0.75