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Targeted disruption of the alpha isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators.
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Mol Cell Biol
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1995
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7.12
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2
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Soluble epoxide hydrolase regulates hydrolysis of vasoactive epoxyeicosatrienoic acids.
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Circ Res
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2000
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3.70
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3
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Clin Pharmacol Ther
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4
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The pharmacogenetics research network: from SNP discovery to clinical drug response.
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Clin Pharmacol Ther
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2007
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2.18
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5
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Clinical pharmacogenetics implementation consortium guidelines for HLA-B genotype and abacavir dosing.
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Clin Pharmacol Ther
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2012
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1.88
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6
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Human liver carbamazepine metabolism. Role of CYP3A4 and CYP2C8 in 10,11-epoxide formation.
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Biochem Pharmacol
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1994
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1.49
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7
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Amodiaquine metabolism is impaired by common polymorphisms in CYP2C8: implications for malaria treatment in Africa.
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Clin Pharmacol Ther
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2007
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1.39
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8
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Inhibition of renal arachidonic acid omega-hydroxylase activity with ABT reduces blood pressure in the SHR.
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Am J Physiol
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1998
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1.29
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9
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Irinotecan-induced diarrhea: functional significance of the polymorphic ABCC2 transporter protein.
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Clin Pharmacol Ther
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10
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Functional characterization of liver enhancers that regulate drug-associated transporters.
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Clin Pharmacol Ther
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11
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Clin Pharmacol Ther
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12
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Increased CYP2J expression and epoxyeicosatrienoic acid formation in spontaneously hypertensive rat kidney.
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Mol Pharmacol
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13
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Interactions of HIV protease inhibitors with a human organic cation transporter in a mammalian expression system.
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0.92
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Functional characterization of ABCC2 promoter polymorphisms and allele-specific expression.
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Pharmacogenomics J
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15
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Structural determination of the substrate specificities and regioselectivities of the rat and human fatty acid omega-hydroxylases.
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Arch Biochem Biophys
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0.89
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16
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Structure-function relationships of human liver cytochromes P450 3A: aflatoxin B1 metabolism as a probe.
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Biochemistry
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17
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Differential renal gene expression in prehypertensive and hypertensive spontaneously hypertensive rats.
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Am J Physiol Renal Physiol
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The effects of a diet rich in docosahexaenoic acid on organ and vascular fatty acid composition in spontaneously hypertensive rats.
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Prostaglandins Leukot Essent Fatty Acids
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Discovery of regulatory elements in human ATP-binding cassette transporters through expression quantitative trait mapping.
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Pharmacogenomics J
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Structure activity relationship of human microsomal epoxide hydrolase inhibition by amide and acid analogues of valproic acid.
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Pharm Res
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Docosahexaenoic acid is an antihypertensive nutrient that affects aldosterone production in SHR.
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Carbamazepine-valnoctamide interaction in epileptic patients: in vitro/in vivo correlation.
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Epilepsia
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0.78
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