|
1
|
Gene therapy for immunodeficiency due to adenosine deaminase deficiency.
|
N Engl J Med
|
2009
|
8.20
|
|
2
|
Lentiviral hematopoietic stem cell gene therapy in patients with Wiskott-Aldrich syndrome.
|
Science
|
2013
|
5.64
|
|
3
|
Molecular response to treatment redefines all prognostic factors in children and adolescents with B-cell precursor acute lymphoblastic leukemia: results in 3184 patients of the AIEOP-BFM ALL 2000 study.
|
Blood
|
2010
|
4.17
|
|
4
|
A treatment protocol for infants younger than 1 year with acute lymphoblastic leukaemia (Interfant-99): an observational study and a multicentre randomised trial.
|
Lancet
|
2007
|
3.94
|
|
5
|
Multicenter independent assessment of outcomes in chronic myeloid leukemia patients treated with imatinib.
|
J Natl Cancer Inst
|
2011
|
3.51
|
|
6
|
Imatinib after induction for treatment of children and adolescents with Philadelphia-chromosome-positive acute lymphoblastic leukaemia (EsPhALL): a randomised, open-label, intergroup study.
|
Lancet Oncol
|
2012
|
2.29
|
|
7
|
Asociación de Hemato-Oncología Pediátrica de Centro América (AHOPCA): a model for sustainable development in pediatric oncology.
|
Pediatr Blood Cancer
|
2013
|
2.23
|
|
8
|
Late MRD response determines relapse risk overall and in subsets of childhood T-cell ALL: results of the AIEOP-BFM-ALL 2000 study.
|
Blood
|
2011
|
2.18
|
|
9
|
Adiponectin and hypertension in normal-weight and obese children.
|
Am J Hypertens
|
2012
|
2.09
|
|
10
|
IKZF1 status as a prognostic feature in BCR-ABL1-positive childhood ALL.
|
Blood
|
2013
|
1.91
|
|
11
|
Risk of relapse of childhood acute lymphoblastic leukemia is predicted by flow cytometric measurement of residual disease on day 15 bone marrow.
|
J Clin Oncol
|
2009
|
1.86
|
|
12
|
Carotid plaque echolucency increases the risk of stroke in carotid stenting: the Imaging in Carotid Angioplasty and Risk of Stroke (ICAROS) study.
|
Circulation
|
2004
|
1.82
|
|
13
|
Pulses of vincristine and dexamethasone in addition to intensive chemotherapy for children with intermediate-risk acute lymphoblastic leukaemia: a multicentre randomised trial.
|
Lancet
|
2007
|
1.68
|
|
14
|
PACSIN2 polymorphism influences TPMT activity and mercaptopurine-related gastrointestinal toxicity.
|
Hum Mol Genet
|
2012
|
1.66
|
|
15
|
Maternal perception of excess weight in children: a survey conducted by paediatricians in the province of Milan.
|
Acta Paediatr
|
2005
|
1.63
|
|
16
|
Association between serum values of C-reactive protein and cytokine production in whole blood of patients with type 2 diabetes.
|
Clin Sci (Lond)
|
2007
|
1.63
|
|
17
|
Clinical outcome of children with newly diagnosed Philadelphia chromosome-positive acute lymphoblastic leukemia treated between 1995 and 2005.
|
J Clin Oncol
|
2010
|
1.62
|
|
18
|
Long-term results of a randomized trial on extended use of high dose L-asparaginase for standard risk childhood acute lymphoblastic leukemia.
|
J Clin Oncol
|
2005
|
1.58
|
|
19
|
Pharmacokinetics of daunorubicin and daunorubicinol in infants with leukemia treated in the interfant 99 protocol.
|
Pediatr Blood Cancer
|
2010
|
1.54
|
|
20
|
Nutritional status of children during treatment for acute lymphoblastic leukemia in Guatemala.
|
Pediatr Blood Cancer
|
2012
|
1.51
|
|
21
|
Atrial fibrillation and morbidity and mortality in a cohort of long-term hemodialysis patients.
|
Am J Kidney Dis
|
2008
|
1.46
|
|
22
|
[A set of indicators to monitor the adherence to the guidelines for the diagnosis and treatment of breast cancer].
|
Epidemiol Prev
|
2014
|
1.44
|
|
23
|
Maternal polymorphisms for methyltetrahydrofolate reductase and methionine synthetase reductase and risk of children with Down syndrome.
|
Am J Obstet Gynecol
|
2009
|
1.42
|
|
24
|
Treatment reduction in highly selected standard-risk childhood acute lymphoblastic leukemia. The AIEOP ALL-9501 study.
|
Haematologica
|
2005
|
1.40
|
|
25
|
Modulation of hepcidin production during hypoxia-induced erythropoiesis in humans in vivo: data from the HIGHCARE project.
|
Blood
|
2010
|
1.37
|
|
26
|
Chemotherapy versus allogeneic transplantation for very-high-risk childhood acute lymphoblastic leukaemia in first complete remission: comparison by genetic randomisation in an international prospective study.
|
Lancet
|
2005
|
1.37
|
|
27
|
Improving outcomes for children with cancer in low-income countries in Latin America: a report on the recent meetings of the Monza International School of Pediatric Hematology/Oncology (MISPHO)-Part I.
|
Pediatr Blood Cancer
|
2007
|
1.22
|
|
28
|
Improved outcome with hematopoietic stem cell transplantation in a poor prognostic subgroup of infants with mixed-lineage-leukemia (MLL)-rearranged acute lymphoblastic leukemia: results from the Interfant-99 Study.
|
Blood
|
2010
|
1.18
|
|
29
|
What is the relevance of Ikaros gene deletions as a prognostic marker in pediatric Philadelphia-negative B-cell precursor acute lymphoblastic leukemia?
|
Haematologica
|
2013
|
1.14
|
|
30
|
New policies to address the global burden of childhood cancers.
|
Lancet Oncol
|
2013
|
1.12
|
|
31
|
Frequencies and prognostic impact of RAS mutations in MLL-rearranged acute lymphoblastic leukemia in infants.
|
Haematologica
|
2013
|
1.11
|
|
32
|
Usefulness of waist circumference for the identification of childhood hypertension.
|
J Hypertens
|
2008
|
1.10
|
|
33
|
Long-term results of the AIEOP-ALL-95 Trial for Childhood Acute Lymphoblastic Leukemia: insight on the prognostic value of DNA index in the framework of Berlin-Frankfurt-Muenster based chemotherapy.
|
J Clin Oncol
|
2008
|
1.09
|
|
34
|
Serum uric acid and blood pressure in children at cardiovascular risk.
|
Pediatrics
|
2013
|
1.07
|
|
35
|
A single high dose of idarubicin combined with high-dose ARA-C for treatment of first relapse in childhood 'high-risk' acute lymphoblastic leukaemia: a study of the AIEOP group.
|
Br J Haematol
|
2002
|
1.06
|
|
36
|
Hepatocellular carcinoma in cirrhotic liver disease: functional computed tomography with perfusion imaging in the assessment of tumor vascularization.
|
Acad Radiol
|
2008
|
1.05
|
|
37
|
Nutritional status at diagnosis is related to clinical outcomes in children and adolescents with cancer: a perspective from Central America.
|
Eur J Cancer
|
2011
|
1.03
|
|
38
|
Clinico-biological features of 5202 patients with acute lymphoblastic leukemia enrolled in the Italian AIEOP and GIMEMA protocols and stratified in age cohorts.
|
Haematologica
|
2013
|
1.01
|
|
39
|
Outcome of congenital acute lymphoblastic leukemia treated on the Interfant-99 protocol.
|
Blood
|
2009
|
1.01
|
|
40
|
Acute lymphoblastic leukemia and Down syndrome: presenting features and treatment outcome in the experience of the Italian Association of Pediatric Hematology and Oncology (AIEOP).
|
Cancer
|
2008
|
0.99
|
|
41
|
Chromosomal aberrations in bladder cancer: fresh versus formalin fixed paraffin embedded tissue and targeted FISH versus wide microarray-based CGH analysis.
|
PLoS One
|
2011
|
0.99
|
|
42
|
Second malignant neoplasms after treatment of childhood acute lymphoblastic leukemia.
|
J Clin Oncol
|
2013
|
0.96
|
|
43
|
Marriage and parenthood among childhood cancer survivors: a report from the Italian AIEOP Off-Therapy Registry.
|
Haematologica
|
2011
|
0.95
|
|
44
|
Are chronic myeloid leukemia patients more at risk for second malignancies? A population-based study.
|
Am J Epidemiol
|
2010
|
0.95
|
|
45
|
Ethmoid adenocarcinoma--from craniofacial to endoscopic resections: a single-institution experience over 25 years.
|
Otolaryngol Head Neck Surg
|
2011
|
0.94
|
|
46
|
MR diffusion imaging for preoperative staging of myometrial invasion in patients with endometrial cancer: a systematic review and meta-analysis.
|
Eur Radiol
|
2014
|
0.94
|
|
47
|
Eligibility for allogeneic transplantation in very high risk childhood acute lymphoblastic leukemia: the impact of the waiting time.
|
Haematologica
|
2008
|
0.94
|
|
48
|
Epidemiology and survival analysis of cystic fibrosis in an area of intense neonatal screening over 30 years.
|
Am J Epidemiol
|
2002
|
0.91
|
|
49
|
Linking genomic lesions with minimal residual disease improves prognostic stratification in children with T-cell acute lymphoblastic leukaemia.
|
Leuk Res
|
2013
|
0.90
|
|
50
|
Long term survivors of childhood cancer: cure and care. The Erice statement.
|
Eur J Cancer
|
2007
|
0.90
|
|
51
|
Insulin resistance, prehypertension, hypertension and blood pressure values in paediatric age.
|
J Hypertens
|
2012
|
0.90
|
|
52
|
Time point-dependent concordance of flow cytometry and real-time quantitative polymerase chain reaction for minimal residual disease detection in childhood acute lymphoblastic leukemia.
|
Haematologica
|
2012
|
0.89
|
|
53
|
High prevalence of hypertension in normal and underweight Indian children.
|
J Hypertens
|
2011
|
0.89
|
|
54
|
Outcome of very late relapse in children with acute lymphoblastic leukemia.
|
Haematologica
|
2004
|
0.89
|
|
55
|
Performance of binary markers for censored failure time outcome: nonparametric approach based on proportions.
|
Stat Med
|
2011
|
0.89
|
|
56
|
Improving recruitment to clinical trials for cancer in childhood.
|
Lancet Oncol
|
2008
|
0.88
|
|
57
|
A weighted Kaplan-Meier estimator for matched data with application to the comparison of chemotherapy and bone-marrow transplant in leukaemia.
|
Stat Med
|
2002
|
0.88
|
|
58
|
Endometrial cancer: correlation of apparent diffusion coefficient with tumor grade, depth of myometrial invasion, and presence of lymph node metastases.
|
AJR Am J Roentgenol
|
2011
|
0.87
|
|
59
|
Survival after relapse in children with solid tumors: a follow-up study from the Italian off-therapy registry.
|
Pediatr Blood Cancer
|
2006
|
0.87
|
|
60
|
Risk factors for highly pathogenic H7N1 avian influenza virus infection in poultry during the 1999-2000 epidemic in Italy.
|
Vet J
|
2008
|
0.87
|
|
61
|
FLT3 internal tandem duplication in childhood acute myeloid leukaemia: association with hyperleucocytosis in acute promyelocytic leukaemia.
|
Br J Haematol
|
2003
|
0.86
|
|
62
|
Improved outcome in high-risk childhood acute lymphoblastic leukemia defined by prednisone-poor response treated with double Berlin-Frankfurt-Muenster protocol II.
|
Blood
|
2002
|
0.86
|
|
63
|
Childhood high-risk acute lymphoblastic leukemia in first remission: results after chemotherapy or transplant from the AIEOP ALL 2000 study.
|
Blood
|
2014
|
0.85
|
|
64
|
Prediction of progression-free survival in patients presenting with hepatocellular carcinoma within the Milan criteria.
|
Liver Transpl
|
2010
|
0.85
|
|
65
|
A case series of chronic haemodialysis patients: mortality, sudden death, and QT interval.
|
Europace
|
2013
|
0.84
|
|
66
|
Axillary lymphadenectomy for breast cancer. A randomized controlled trial comparing a bipolar vessel sealing system to the conventional technique.
|
Breast
|
2012
|
0.84
|
|
67
|
Childhood acute lymphoblastic leukemia in Nicaragua: long-term results in the context of an international cooperative program.
|
Pediatr Blood Cancer
|
2013
|
0.83
|
|
68
|
Iron accumulation in chronic hepatitis C: relation of hepatic iron distribution, HFE genotype, and disease course.
|
Am J Clin Pathol
|
2005
|
0.83
|
|
69
|
Enhanced recovery strategies in colorectal surgery: is the compliance with the whole program required to achieve the target?
|
Int J Colorectal Dis
|
2013
|
0.83
|
|
70
|
The controversy of varicella vaccination in children with acute lymphoblastic leukemia.
|
Pediatr Blood Cancer
|
2010
|
0.82
|
|
71
|
Impact of IKZF1 deletions on IKZF1 expression and outcome in Philadelphia chromosome negative childhood BCP-ALL. Reply to "incidence and biological significance of IKZF1/Ikaros gene deletions in pediatric Philadelphia chromosome negative and Philadelphia chromosome positive B-cell precursor acute lymphoblastic leukemia".
|
Haematologica
|
2013
|
0.82
|
|
72
|
Hypertension, prehypertension, and transient elevated blood pressure in children: association with weight excess and waist circumference.
|
Am J Hypertens
|
2010
|
0.82
|
|
73
|
The nephrologist's anticoagulation treatment patterns/regimens in chronic hemodialysis patients with atrial fibrillation.
|
J Nephrol
|
2014
|
0.81
|
|
74
|
Oxidative stress biomarkers and chromogranin A in uremic patients: effects of dialytic treatment.
|
Clin Biochem
|
2010
|
0.81
|
|
75
|
Short-term respiratory outcomes in late preterm infants.
|
Ital J Pediatr
|
2014
|
0.81
|
|
76
|
Glutathione S-transferase homozygous deletions and relapse in childhood acute lymphoblastic leukemia: a novel study design in a large Italian AIEOP cohort.
|
Pharmacogenomics
|
2012
|
0.80
|
|
77
|
Multivariate permutation test to compare survival curves for matched data.
|
BMC Med Res Methodol
|
2013
|
0.80
|
|
78
|
Prospective molecular monitoring of BCR/ABL transcript in children with Ph+ acute lymphoblastic leukaemia unravels differences in treatment response.
|
Br J Haematol
|
2002
|
0.80
|
|
79
|
Myometrial invasion in endometrial cancer: diagnostic performance of diffusion-weighted MR imaging at 1.5-T.
|
Eur Radiol
|
2009
|
0.80
|
|
80
|
Role of treatment intensification in infants with acute lymphoblastic leukemia: results of two consecutive AIEOP studies.
|
Haematologica
|
2006
|
0.79
|
|
81
|
The thirteenth international childhood acute lymphoblastic leukemia workshop report: La Jolla, CA, USA, December 7-9, 2011.
|
Pediatr Blood Cancer
|
2012
|
0.79
|
|
82
|
Effects of exercise training on heart rate and QT interval in healthy young individuals: are there gender differences?
|
Europace
|
2007
|
0.79
|
|
83
|
Risk of repeated febrile episodes during chemotherapy-induced granulocytopenia in children with cancer: a prospective single center study.
|
J Chemother
|
2012
|
0.78
|
|
84
|
Perfusion computed tomographic assessment of early hepatocellular carcinoma in cirrhotic liver disease: initial observations.
|
J Comput Assist Tomogr
|
2009
|
0.78
|
|
85
|
Pharmacokinetics of high-dose methotrexate in infants treated for acute lymphoblastic leukemia.
|
Pediatr Blood Cancer
|
2009
|
0.78
|
|
86
|
Defining the correct role of minimal residual disease tests in the management of acute lymphoblastic leukaemia.
|
Br J Haematol
|
2011
|
0.78
|
|
87
|
Decreased induction morbidity and mortality following modification to induction therapy in infants with acute lymphoblastic leukemia enrolled on AALL0631: a report from the Children's Oncology Group.
|
Pediatr Blood Cancer
|
2014
|
0.78
|
|
88
|
ADC maps in the prediction of pelvic lymph nodal metastatic regions in endometrial cancer.
|
Eur Radiol
|
2012
|
0.77
|
|
89
|
Challenges for children and adolescents with cancer in Europe: the SIOP-Europe agenda.
|
Pediatr Blood Cancer
|
2014
|
0.77
|
|
90
|
Correspondence between neurophysiological and clinical measurements of chemotherapy-induced peripheral neuropathy: secondary analysis of data from the CI-PeriNomS study.
|
J Peripher Nerv Syst
|
2014
|
0.77
|
|
91
|
Genotypes of the glutathione S-transferase superfamily do not correlate with outcome of childhood acute lymphoblastic leukemia.
|
Leukemia
|
2003
|
0.77
|
|
92
|
The role of blood pressure, body weight and fat distribution on left ventricular mass, diastolic function and cardiac geometry in children.
|
J Hypertens
|
2015
|
0.77
|
|
93
|
Transplantation in childhood very high risk acute lymphoblastic leukemia in first complete remission: where are we now?
|
J Clin Oncol
|
2007
|
0.76
|
|
94
|
Efficacy and safety of venous angioplasty of the extracranial veins for multiple sclerosis. Brave dreams study (brain venous drainage exploited against multiple sclerosis): study protocol for a randomized controlled trial.
|
Trials
|
2012
|
0.76
|
|
95
|
Feeding tolerance of preterm infants appropriate for gestational age (AGA) as compared to those small for gestational age (SGA).
|
J Matern Fetal Neonatal Med
|
2013
|
0.76
|
|
96
|
A unified model for estimating and testing familial aggregation.
|
Stat Med
|
2013
|
0.76
|
|
97
|
TNF-α SNP rs1800629 and risk of relapse in childhood acute lymphoblastic leukemia: relation to immunophenotype.
|
Pharmacogenomics
|
2014
|
0.75
|
|
98
|
Importance of minimal residual disease testing during the second year of disease: still no answer?
|
J Clin Oncol
|
2003
|
0.75
|
|
99
|
Response to "Low serum adiponectin levels and endothelial dysfunction in childhood hypertension".
|
Am J Hypertens
|
2013
|
0.75
|
|
100
|
Glutamine-enriched nutrition does not reduce mucosal morbidity or complications after stem-cell transplantation for childhood malignancies: a prospective randomized study.
|
Transplantation
|
2011
|
0.75
|
|
101
|
[Methodologic problems in the analysis of competing risks].
|
Epidemiol Prev
|
2002
|
0.75
|
|
102
|
A randomized and controlled study of noninvasive hemodynamic monitoring as a guide to drug treatment of uncontrolled hypertensive patients.
|
J Hypertens
|
2015
|
0.75
|
|
103
|
Analysis of interval-censored longitudinal data with application to onco-haematology.
|
Stat Med
|
2005
|
0.75
|
|
104
|
Evaluation of alternative prognostic stratifications by prediction accuracy measures on individual survival with application to childhood leukaemia.
|
Eur J Cancer
|
2009
|
0.75
|
|
105
|
Preoperative Oral Carbohydrate Load Versus Placebo in Major Elective Abdominal Surgery (PROCY): A Randomized, Placebo-controlled, Multicenter, Phase III Trial.
|
Ann Surg
|
2017
|
0.75
|
|
106
|
Robust non-parametric one-sample tests for the analysis of recurrent events.
|
Stat Med
|
2010
|
0.75
|