|
1
|
MicroRNA-221/222 confers tamoxifen resistance in breast cancer by targeting p27Kip1.
|
J Biol Chem
|
2008
|
4.56
|
|
2
|
Methylation mediated silencing of MicroRNA-1 gene and its role in hepatocellular carcinogenesis.
|
Cancer Res
|
2008
|
3.16
|
|
3
|
5-Aza-deoxycytidine induces selective degradation of DNA methyltransferase 1 by a proteasomal pathway that requires the KEN box, bromo-adjacent homology domain, and nuclear localization signal.
|
Mol Cell Biol
|
2005
|
3.05
|
|
4
|
Down-regulation of micro-RNA-1 (miR-1) in lung cancer. Suppression of tumorigenic property of lung cancer cells and their sensitization to doxorubicin-induced apoptosis by miR-1.
|
J Biol Chem
|
2008
|
3.00
|
|
5
|
Role of microRNA-155 at early stages of hepatocarcinogenesis induced by choline-deficient and amino acid-defined diet in C57BL/6 mice.
|
Hepatology
|
2009
|
2.29
|
|
6
|
Role of human ribosomal RNA (rRNA) promoter methylation and of methyl-CpG-binding protein MBD2 in the suppression of rRNA gene expression.
|
J Biol Chem
|
2003
|
2.15
|
|
7
|
Suppression of the protein tyrosine phosphatase receptor type O gene (PTPRO) by methylation in hepatocellular carcinomas.
|
Oncogene
|
2003
|
1.64
|
|
8
|
Inhibitors of histone deacetylase and DNA methyltransferase synergistically activate the methylated metallothionein I promoter by activating the transcription factor MTF-1 and forming an open chromatin structure.
|
Mol Cell Biol
|
2002
|
1.64
|
|
9
|
DNA methyltransferase 3b regulates nerve growth factor-induced differentiation of PC12 cells by recruiting histone deacetylase 2.
|
Mol Cell Biol
|
2005
|
1.41
|
|
10
|
Metallothionein expression is suppressed in primary human hepatocellular carcinomas and is mediated through inactivation of CCAAT/enhancer binding protein alpha by phosphatidylinositol 3-kinase signaling cascade.
|
Cancer Res
|
2007
|
1.40
|
|
11
|
Anti-microRNA-222 (anti-miR-222) and -181B suppress growth of tamoxifen-resistant xenografts in mouse by targeting TIMP3 protein and modulating mitogenic signal.
|
J Biol Chem
|
2011
|
1.24
|
|
12
|
Physical and functional interaction of DNA methyltransferase 3A with Mbd3 and Brg1 in mouse lymphosarcoma cells.
|
Cancer Res
|
2005
|
1.17
|
|
13
|
Methylation and silencing of protein tyrosine phosphatase receptor type O in chronic lymphocytic leukemia.
|
Clin Cancer Res
|
2007
|
1.09
|
|
14
|
HOXB13, a target of DNMT3B, is methylated at an upstream CpG island, and functions as a tumor suppressor in primary colorectal tumors.
|
PLoS One
|
2010
|
1.08
|
|
15
|
PTPROt inactivates the oncogenic fusion protein BCR/ABL and suppresses transformation of K562 cells.
|
J Biol Chem
|
2008
|
1.07
|
|
16
|
Analysis of promoter methylation and its role in silencing metallothionein I gene expression in tumor cells.
|
Methods Enzymol
|
2002
|
1.04
|
|
17
|
Estrogen-mediated suppression of the gene encoding protein tyrosine phosphatase PTPRO in human breast cancer: mechanism and role in tamoxifen sensitivity.
|
Mol Endocrinol
|
2008
|
0.93
|
|
18
|
Suppression of metallothionein-I/II expression and its probable molecular mechanisms.
|
Environ Health Perspect
|
2002
|
0.91
|
|
19
|
Mitochondrial transcription factor A and its downstream targets are up-regulated in a rat hepatoma.
|
J Biol Chem
|
2002
|
0.89
|
|
20
|
Reduced susceptibility of DNA methyltransferase 1 hypomorphic (Dnmt1N/+) mice to hepatic steatosis upon feeding liquid alcohol diet.
|
PLoS One
|
2012
|
0.83
|