Published in Ocul Immunol Inflamm on March 16, 2007
The immunoconjugate "icon" targets aberrantly expressed endothelial tissue factor causing regression of endometriosis. Am J Pathol (2009) 1.06
Targeting tissue factor on tumour cells and angiogenic vascular endothelial cells by factor VII-targeted verteporfin photodynamic therapy for breast cancer in vitro and in vivo in mice. BMC Cancer (2010) 0.95
Selective and effective killing of angiogenic vascular endothelial cells and cancer cells by targeting tissue factor using a factor VII-targeted photodynamic therapy for breast cancer. Breast Cancer Res Treat (2010) 0.89
Effective treatment of chemoresistant breast cancer in vitro and in vivo by a factor VII-targeted photodynamic therapy. Br J Cancer (2011) 0.87
Fusion Proteins for Half-Life Extension of Biologics as a Strategy to Make Biobetters. BioDrugs (2015) 0.87
Evidence for enhanced tissue factor expression in age-related macular degeneration. Lab Invest (2010) 0.86
Targeting Neovascularization in Ischemic Retinopathy: Recent Advances. Expert Rev Ophthalmol (2013) 0.84
hI-con1, a factor VII-IgGFc chimeric protein targeting tissue factor for immunotherapy of uterine serous papillary carcinoma. Br J Cancer (2010) 0.84
Tissue factor expression in ovarian cancer: implications for immunotherapy with hI-con1, a factor VII-IgGF(c) chimeric protein targeting tissue factor. Clin Exp Metastasis (2011) 0.82
Natural killer cells are crucial for the efficacy of Icon (factor VII/human IgG1 Fc) immunotherapy in human tongue cancer. BMC Immunol (2010) 0.81
The effects of small interfering RNA-targeting tissue factor on an in vitro model of neovascularization. Mol Vis (2013) 0.78
Tissue factor is an angiogenic-specific receptor for factor VII-targeted immunotherapy and photodynamic therapy. Angiogenesis (2016) 0.77
Endometriosis, angiogenesis and tissue factor. Scientifica (Cairo) (2012) 0.76
Tissue factor with age-related macular degeneration. Int J Ophthalmol (2012) 0.75
Is there tachyphylaxis to intravitreal anti-vascular endothelial growth factor pharmacotherapy in age-related macular degeneration? Ophthalmology (2008) 3.90
Severe chronic experimental autoimmune uveitis (EAU) of the C57BL/6 mouse induced by adoptive transfer of IRBP1-20-specific T cells. Exp Eye Res (2005) 1.95
Role of complement and complement membrane attack complex in laser-induced choroidal neovascularization. J Immunol (2005) 1.89
Generation of an inbred miniature pig model of retinitis pigmentosa. Invest Ophthalmol Vis Sci (2012) 1.87
Adult retinal pigment epithelial transplantation in exudative age-related macular degeneration. Am J Ophthalmol (2007) 1.82
Role of human noncoding RNAs in the control of tumorigenesis. Proc Natl Acad Sci U S A (2009) 1.76
Characterization of IL-17+ interphotoreceptor retinoid-binding protein-specific T cells in experimental autoimmune uveitis. Invest Ophthalmol Vis Sci (2007) 1.49
Major role of gamma delta T cells in the generation of IL-17+ uveitogenic T cells. J Immunol (2009) 1.48
Roles of PSF protein and VL30 RNA in reversible gene regulation. Proc Natl Acad Sci U S A (2005) 1.43
Complement activation via alternative pathway is critical in the development of laser-induced choroidal neovascularization: role of factor B and factor H. J Immunol (2006) 1.42
[Frequency and predictors of atrial fibrillation in severe mitral regurgitation]. Anadolu Kardiyol Derg (2003) 1.38
Tolerance is dependent on complement C3 fragment iC3b binding to antigen-presenting cells. Nat Med (2003) 1.38
Binding of mouse VL30 retrotransposon RNA to PSF protein induces genes repressed by PSF: effects on steroidogenesis and oncogenesis. Proc Natl Acad Sci U S A (2004) 1.35
Epithelial-mesenchymal transition and proliferation of retinal pigment epithelial cells initiated upon loss of cell-cell contact. Invest Ophthalmol Vis Sci (2009) 1.29
Differentiation of induced pluripotent stem cells of swine into rod photoreceptors and their integration into the retina. Stem Cells (2011) 1.29
Behavioral and anatomical abnormalities in a sodium iodate-induced model of retinal pigment epithelium degeneration. Exp Eye Res (2005) 1.29
Mouse gammadelta T cells are capable of expressing MHC class II molecules, and of functioning as antigen-presenting cells. J Neuroimmunol (2008) 1.25
Regulation of proto-oncogene transcription, cell proliferation, and tumorigenesis in mice by PSF protein and a VL30 noncoding RNA. Proc Natl Acad Sci U S A (2009) 1.23
Anti-inflammatory role of IL-17 in experimental autoimmune uveitis. J Immunol (2009) 1.23
Myelin/oligodendrocyte glycoprotein-specific T-cells induce severe optic neuritis in the C57BL/6 mouse. Invest Ophthalmol Vis Sci (2004) 1.22
Oxidative stress and the regulation of complement activation in human glaucoma. Invest Ophthalmol Vis Sci (2010) 1.21
Decreased visual function after patchy loss of retinal pigment epithelium induced by low-dose sodium iodate. Invest Ophthalmol Vis Sci (2009) 1.20
Taz-tead1 links cell-cell contact to zeb1 expression, proliferation, and dedifferentiation in retinal pigment epithelial cells. Invest Ophthalmol Vis Sci (2010) 1.19
Immunotherapy for choroidal neovascularization in a laser-induced mouse model simulating exudative (wet) macular degeneration. Proc Natl Acad Sci U S A (2003) 1.17
Retroviral-mediated transmission of a mouse VL30 RNA to human melanoma cells promotes metastasis in an immunodeficient mouse model. Proc Natl Acad Sci U S A (2002) 1.15
The immunoconjugate "icon" targets aberrantly expressed endothelial tissue factor causing regression of endometriosis. Am J Pathol (2009) 1.06
Primary retinal detachment repair: comparison of 1-year outcomes of four surgical techniques. Retina (2011) 1.06
Uveitis referral pattern in a Midwest University Eye Center. Ocul Immunol Inflamm (2003) 1.05
Survival of allogeneic porcine retinal pigment epithelial sheets after subretinal transplantation. Invest Ophthalmol Vis Sci (2004) 1.05
Conversion of monophasic to recurrent autoimmune disease by autoreactive T cell subsets. J Immunol (2003) 1.05
A shared epitope of the interphotoreceptor retinoid-binding protein recognized by the CD4+ and CD8+ autoreactive T cells. J Immunol (2005) 1.04
Retinal pigment epithelium damage enhances expression of chemoattractants and migration of bone marrow-derived stem cells. Invest Ophthalmol Vis Sci (2006) 1.04
Encephalitogenic activity of truncated myelin oligodendrocyte glycoprotein (MOG) peptides and their recognition by CD8+ MOG-specific T cells on oligomeric MHC class I molecules. Int Immunol (2003) 1.02
Zeb1 mutant mice as a model of posterior corneal dystrophy. Invest Ophthalmol Vis Sci (2008) 1.02
Reengineering of aged Bruch's membrane to enhance retinal pigment epithelium repopulation. Invest Ophthalmol Vis Sci (2004) 1.00
Suppression of complement regulatory proteins (CRPs) exacerbates experimental autoimmune anterior uveitis (EAAU). J Immunol (2006) 1.00
The complement system plays a critical role in the development of experimental autoimmune anterior uveitis. Invest Ophthalmol Vis Sci (2006) 1.00
Zeb1 represses Mitf and regulates pigment synthesis, cell proliferation, and epithelial morphology. Invest Ophthalmol Vis Sci (2009) 1.00
Regulatory effect of gammadelta T cells on IL-17+ uveitogenic T cells. Invest Ophthalmol Vis Sci (2010) 1.00
Novel role for a complement regulatory protein (CD46) in retinal pigment epithelial adhesion. Invest Ophthalmol Vis Sci (2003) 0.99
Blockade of the interaction of leukotriene b4 with its receptor prevents development of autoimmune uveitis. Invest Ophthalmol Vis Sci (2006) 0.99
Retinal self-antigen induces a predominantly Th1 effector response in Axl and Mertk double-knockout mice. J Immunol (2011) 0.99
Synthesis and secretion of hemoglobin by retinal pigment epithelium. Invest Ophthalmol Vis Sci (2008) 0.99
Role of CD25+ dendritic cells in the generation of Th17 autoreactive T cells in autoimmune experimental uveitis. J Immunol (2012) 0.98
Characterization of rat CD8+ uveitogenic T cells specific for interphotoreceptor retinal-binding protein 1177-1191. J Immunol (2004) 0.98
Chronic recurrent autoimmune uveitis with progressive photoreceptor damage induced in rats by transfer of IRBP-specific T cells. J Neuroimmunol (2005) 0.97
Large dielectric constant and high thermal conductivity in poly(vinylidene fluoride)/barium titanate/silicon carbide three-phase nanocomposites. ACS Appl Mater Interfaces (2011) 0.97
Activated gammadelta T cells promote the activation of uveitogenic T cells and exacerbate EAU development. Invest Ophthalmol Vis Sci (2011) 0.97
IL-22-induced regulatory CD11b+ APCs suppress experimental autoimmune uveitis. J Immunol (2011) 0.96
Effect of physician reimbursement methodology on the rate and cost of cataract surgery. Arch Ophthalmol (2005) 0.96
In vitro activation of CD8 interphotoreceptor retinoid-binding protein-specific T cells requires not only antigenic stimulation but also exogenous growth factors. J Immunol (2006) 0.96
Suspected simultaneous bilateral anterior ischemic optic neuropathy in a patient with Behçet's disease. Ocul Immunol Inflamm (2005) 0.95
IL-23 receptor expression on γδ T cells correlates with their enhancing or suppressive effects on autoreactive T cells in experimental autoimmune uveitis. J Immunol (2013) 0.93
Reactivation of uveitogenic T cells by retinal astrocytes derived from experimental autoimmune uveitis-prone B10RIII mice. Invest Ophthalmol Vis Sci (2008) 0.93
Regulatory role of TLR ligands on the activation of autoreactive T cells by retinal astrocytes. Invest Ophthalmol Vis Sci (2009) 0.93
Type I collagen is the autoantigen in experimental autoimmune anterior uveitis. J Immunol (2004) 0.93
Extracellular matrix ligands promote RPE attachment to inner Bruch's membrane. Curr Eye Res (2002) 0.93
Minimally activated CD8 autoreactive T cells specific for IRBP express a high level of Foxp3 and are functionally suppressive. Invest Ophthalmol Vis Sci (2007) 0.93
Pathogenesis of age-related macular degeneration. Trends Mol Med (2004) 0.93
Endogenous bone marrow derived cells express retinal pigment epithelium cell markers and migrate to focal areas of RPE damage. Invest Ophthalmol Vis Sci (2007) 0.93
Double-orifice mitral valve associated with bicuspid aortic valve: a rare case of incomplete form of Shone's complex. Eur J Echocardiogr (2009) 0.93
Enhanced induction of RPE lineage markers in pluripotent neural stem cells engrafted into the adult rat subretinal space. Invest Ophthalmol Vis Sci (2003) 0.92
Anti-CD137 mAb treatment inhibits experimental autoimmune uveitis by limiting expansion and increasing apoptotic death of uveitogenic T cells. Invest Ophthalmol Vis Sci (2005) 0.92
Intraocular diseases - anterior uveitis. Chem Immunol Allergy (2007) 0.92
Retinal pigment epithelial cells activate uveitogenic T cells when they express high levels of MHC class II molecules, but inhibit T cell activation when they express restricted levels. J Neuroimmunol (2003) 0.92
PD-L1(hi) retinal pigment epithelium (RPE) cells elicited by inflammatory cytokines induce regulatory activity in uveitogenic T cells. J Leukoc Biol (2010) 0.91
Systemically transferred hematopoietic stem cells home to the subretinal space and express RPE-65 in a mouse model of retinal pigment epithelium damage. Exp Eye Res (2006) 0.91
Comparison of electrically evoked cortical potential thresholds generated with subretinal or suprachoroidal placement of a microelectrode array in the rabbit. J Neural Eng (2005) 0.91
A new model of experimental autoimmune keratoconjunctivitis sicca (KCS) induced in Lewis rat by the autoantigen Klk1b22. Invest Ophthalmol Vis Sci (2008) 0.90
Direct observation of rotatable uncompensated spins in the exchange bias system Co/CoO-MgO. Nanoscale (2013) 0.90
Maculoplasty for age-related macular degeneration: reengineering Bruch's membrane and the human macula. Prog Retin Eye Res (2006) 0.90
CpG-containing oligodeoxynucleotide 1826 converts the weak uveitogenic rat interphotoreceptor retinoid-binding protein peptide 1181-1191 into a strong uveitogen. J Immunol (2003) 0.89
Retinal pigment epithelium rescues vascular endothelium from retinoic acid-induced apoptosis. Invest Ophthalmol Vis Sci (2006) 0.89
In vivo priming of IL-17(+) uveitogenic T cells is enhanced by Toll ligand receptor (TLR)2 and TLR4 agonists via γδ T cell activation. Mol Immunol (2012) 0.89
Stem cells as tools in regenerative therapy for retinal degeneration. Arch Ophthalmol (2009) 0.89
Retinoic acid inhibits CD25+ dendritic cell expansion and γδ T-cell activation in experimental autoimmune uveitis. Invest Ophthalmol Vis Sci (2013) 0.89
Enhanced hemostatic indices in patients with pulmonary arterial hypertension: an observational study. Thromb Res (2010) 0.88
Ocular regulatory T cells distinguish monophasic from recurrent autoimmune uveitis. Invest Ophthalmol Vis Sci (2008) 0.88
Angioplasty for pediatric renovascular hypertension: a 13-year experience. Diagn Interv Radiol (2014) 0.87
Alcohol linked to enhanced angiogenesis in rat model of choroidal neovascularization. FEBS J (2006) 0.87
A Pro23His mutation alters prenatal rod photoreceptor morphology in a transgenic swine model of retinitis pigmentosa. Invest Ophthalmol Vis Sci (2014) 0.87
Identification of small Sca-1(+), Lin(-), CD45(-) multipotential cells in the neonatal murine retina. Exp Hematol (2009) 0.87
Characterization of autoreactive and bystander IL-17+ T cells induced in immunized C57BL/6 mice. Invest Ophthalmol Vis Sci (2012) 0.87
Factor VII-verteporfin for targeted photodynamic therapy in a rat model of choroidal neovascularization. Invest Ophthalmol Vis Sci (2009) 0.87
Common variants in the BCL9 gene conferring risk of schizophrenia. Arch Gen Psychiatry (2011) 0.87
Retinal Astrocytes respond to IL-17 differently than Retinal Pigment Epithelial cells. J Leukoc Biol (2009) 0.87
The role of Fas-FasL in the development and treatment of ischemic retinopathy. Invest Ophthalmol Vis Sci (2003) 0.86
Cone photoreceptors develop normally in the absence of functional rod photoreceptors in a transgenic swine model of retinitis pigmentosa. Invest Ophthalmol Vis Sci (2014) 0.86
Age-related macular degeneration. Discov Med (2010) 0.86
Triple immune suppression increases short-term survival of porcine fetal retinal pigment epithelium xenografts. Invest Ophthalmol Vis Sci (2003) 0.85
Selective rod degeneration and partial cone inactivation characterize an iodoacetic acid model of Swine retinal degeneration. Invest Ophthalmol Vis Sci (2011) 0.85
The MDGA1 gene confers risk to schizophrenia and bipolar disorder. Schizophr Res (2010) 0.85
Long-term cellular and regional specificity of the photoreceptor toxin, iodoacetic acid (IAA), in the rabbit retina. Vis Neurosci (2008) 0.85
Infiltration of the inflamed eye by NKT cells in a rat model of experimental autoimmune uveitis. J Autoimmun (2003) 0.84