Published in Trends Genet on March 26, 2007
Unraveling a multifactorial late-onset disease: from genetic susceptibility to disease mechanisms for age-related macular degeneration. Annu Rev Genomics Hum Genet (2009) 2.40
Functional roles of bestrophins in ocular epithelia. Prog Retin Eye Res (2009) 1.52
Retinal ultrastructure of murine models of dry age-related macular degeneration (AMD). Prog Retin Eye Res (2010) 1.39
Animal models of age related macular degeneration. Mol Aspects Med (2012) 1.39
Molecular regulation of cigarette smoke induced-oxidative stress in human retinal pigment epithelial cells: implications for age-related macular degeneration. Am J Physiol Cell Physiol (2009) 1.19
A CTRP5 gene S163R mutation knock-in mouse model for late-onset retinal degeneration. Hum Mol Genet (2011) 1.09
Age-related retinal degeneration (arrd2) in a novel mouse model due to a nonsense mutation in the Mdm1 gene. Hum Mol Genet (2008) 0.99
Genetics and molecular pathology of Stargardt-like macular degeneration. Prog Retin Eye Res (2010) 0.95
Development of choroidal neovascularization in rats with advanced intense cyclic light-induced retinal degeneration. Arch Ophthalmol (2010) 0.91
BEST1: the Best Target for Gene and Cell Therapies. Mol Ther (2015) 0.81
Constancy of ERp29 expression in cultured retinal pigment epithelial cells in the Ccl2/Cx3cr1 deficient mouse model of age-related macular degeneration. Curr Eye Res (2008) 0.80
Rapid cohort generation and analysis of disease spectrum of large animal model of cone dystrophy. PLoS One (2013) 0.79
Role of long-chain and very-long-chain polyunsaturated fatty acids in macular degenerations and dystrophies. Clin Lipidol (2011) 0.77
Relationship of stokes radius to the rate of diffusion across Bruch's membrane. Invest Ophthalmol Vis Sci (2011) 0.76
Deletion of myosin VI causes slow retinal optic neuropathy and age-related macular degeneration (AMD)-relevant retinal phenotype. Cell Mol Life Sci (2015) 0.76
Fibulin-4: a novel gene for an autosomal recessive cutis laxa syndrome. Am J Hum Genet (2006) 1.99
Targeted disruption of fibulin-4 abolishes elastogenesis and causes perinatal lethality in mice. Mol Cell Biol (2006) 1.97
Lack of fibulin-3 causes early aging and herniation, but not macular degeneration in mice. Hum Mol Genet (2007) 1.50
Spectral profiling of autofluorescence associated with lipofuscin, Bruch's Membrane, and sub-RPE deposits in normal and AMD eyes. Invest Ophthalmol Vis Sci (2002) 1.49
Fibulin-4 deficiency results in ascending aortic aneurysms: a potential link between abnormal smooth muscle cell phenotype and aneurysm progression. Circ Res (2009) 1.46
Expression and localization of bestrophin during normal mouse development. Invest Ophthalmol Vis Sci (2003) 1.45
Tissue inhibitor of metalloproteinases-3 (TIMP-3) is a binding partner of epithelial growth factor-containing fibulin-like extracellular matrix protein 1 (EFEMP1). Implications for macular degenerations. J Biol Chem (2004) 1.32
Fibulin-4 conducts proper elastogenesis via interaction with cross-linking enzyme lysyl oxidase. Proc Natl Acad Sci U S A (2009) 1.30
A model of best vitelliform macular dystrophy in rats. Invest Ophthalmol Vis Sci (2004) 1.23
Aberrant accumulation of fibulin-3 in the endoplasmic reticulum leads to activation of the unfolded protein response and VEGF expression. Invest Ophthalmol Vis Sci (2005) 1.23
Bestrophin-2 is involved in the generation of intraocular pressure. Invest Ophthalmol Vis Sci (2008) 1.22
Enhanced inflow and outflow rates despite lower IOP in bestrophin-2-deficient mice. Invest Ophthalmol Vis Sci (2008) 1.19
Suppression of Ca2+ signaling in a mouse model of Best disease. Hum Mol Genet (2010) 1.14
Hydrodynamic properties of porcine bestrophin-1 in Triton X-100. Biochim Biophys Acta (2006) 1.13
Failure of pelvic organ support in mice deficient in fibulin-3. Am J Pathol (2008) 1.13
Focus on molecules: fibulin-3 (EFEMP1). Exp Eye Res (2009) 1.09
Regulation of anterior chamber drainage by bicarbonate-sensitive soluble adenylyl cyclase in the ciliary body. J Biol Chem (2011) 0.98
Retinal pigment epithelial cells exhibit unique expression and localization of plasma membrane syntaxins which may contribute to their trafficking phenotype. J Cell Sci (2002) 0.89
Differential effects of Best disease causing missense mutations on bestrophin-1 trafficking. Hum Mol Genet (2013) 0.87
Relationship of stokes radius to the rate of diffusion across Bruch's membrane. Invest Ophthalmol Vis Sci (2011) 0.76
Lack of fibulin-3 alters regenerative tissue responses in the primary olfactory pathway. Matrix Biol (2009) 0.75