Mark A Exley

Author PubWeight™ 41.46‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Adipose tissue invariant NKT cells protect against diet-induced obesity and metabolic disorder through regulatory cytokine production. Immunity 2012 2.80
2 Implications for invariant natural killer T cell ligands due to the restricted presence of isoglobotrihexosylceramide in mammals. Proc Natl Acad Sci U S A 2007 1.84
3 Effects of the administration of high-dose interleukin-2 on immunoregulatory cell subsets in patients with advanced melanoma and renal cell cancer. Clin Cancer Res 2007 1.84
4 The CD1d-binding glycolipid alpha-galactosylceramide enhances humoral immunity to T-dependent and T-independent antigen in a CD1d-dependent manner. Immunology 2006 1.44
5 CD1d ligation on human monocytes directly signals rapid NF-kappaB activation and production of bioactive IL-12. Proc Natl Acad Sci U S A 2005 1.40
6 Hepatic CD1d expression in hepatitis C virus infection and recognition by resident proinflammatory CD1d-reactive T cells. J Immunol 2004 1.27
7 Impaired cell surface expression of human CD1d by the formation of an HIV-1 Nef/CD1d complex. Virology 2005 1.19
8 Hepatitis C virus (HCV)-specific CD8+ cells produce transforming growth factor beta that can suppress HCV-specific T-cell responses. J Virol 2007 1.13
9 Primary deficiency of microsomal triglyceride transfer protein in human abetalipoproteinemia is associated with loss of CD1 function. J Clin Invest 2010 1.06
10 CD1d-restricted T cells regulate dendritic cell function and antitumor immunity in a granulocyte-macrophage colony-stimulating factor-dependent fashion. Proc Natl Acad Sci U S A 2003 1.06
11 Cutting edge: CD1d restriction and Th1/Th2/Th17 cytokine secretion by human Vδ3 T cells. J Immunol 2013 1.05
12 Generation of antitumor invariant natural killer T cell lines in multiple myeloma and promotion of their functions via lenalidomide: a strategy for immunotherapy. Clin Cancer Res 2008 1.01
13 Hyporesponsiveness to natural killer T-cell ligand alpha-galactosylceramide in cancer-bearing state mediated by CD11b+ Gr-1+ cells producing nitric oxide. Cancer Res 2006 0.96
14 The A2aR adenosine receptor controls cytokine production in iNKT cells. Eur J Immunol 2010 0.96
15 CD1d and CD1d-restricted iNKT-cells play a pivotal role in contact hypersensitivity. Exp Dermatol 2005 0.96
16 Defective NKT cell activation by CD1d+ TRAMP prostate tumor cells is corrected by interleukin-12 with α-galactosylceramide. PLoS One 2010 0.94
17 NKT-cell-based immunotherapies in clinical trials. Clin Immunol 2011 0.93
18 Circulating myeloid dendritic cells of advanced cancer patients result in reduced activation and a biased cytokine profile in invariant NKT cells. J Immunol 2008 0.92
19 CD1d-based combination therapy eradicates established tumors in mice. J Immunol 2009 0.92
20 CD1d mediates T-cell-dependent resistance to secondary infection with encephalomyocarditis virus (EMCV) in vitro and immune response to EMCV infection in vivo. J Virol 2006 0.91
21 Direct CD1d-mediated stimulation of APC IL-12 production and protective immune response to virus infection in vivo. J Immunol 2009 0.90
22 Gestation stage-dependent mechanisms of invariant natural killer T cell-mediated pregnancy loss. Proc Natl Acad Sci U S A 2006 0.90
23 Human invariant NKT cell subsets differentially promote differentiation, antibody production, and T cell stimulation by B cells in vitro. J Immunol 2013 0.89
24 Natural killer T cell-based cancer immunotherapy. Clin Cancer Res 2006 0.88
25 CD1d activation and blockade: a new antitumor strategy. J Immunol 2009 0.87
26 Loss of effector and anti-inflammatory natural killer T lymphocyte function in pathogenic simian immunodeficiency virus infection. PLoS Pathog 2012 0.86
27 Phenotypic and functional characterization of long-term cultured rhesus macaque spleen-derived NKT cells. J Immunol 2003 0.85
28 Peripheral blood progenitor cell product contains Th1-biased noninvariant CD1d-reactive natural killer T cells: implications for posttransplant survival. Exp Hematol 2008 0.85
29 Heterogeneity in phenotype and function of CD8+ and CD4/CD8 double-negative Natural Killer T cell subsets in sooty mangabeys. J Med Primatol 2010 0.84
30 Exploiting regulatory T-cell populations for the immunotherapy of cancer. J Immunother 2007 0.84
31 Paucity of CD4+ natural killer T (NKT) lymphocytes in sooty mangabeys is associated with lack of NKT cell depletion after SIV infection. PLoS One 2010 0.84
32 Activation of human invariant natural killer T cells with a thioglycoside analogue of α-galactosylceramide. Clin Immunol 2011 0.84
33 CD1 expression and CD1-restricted T cell activity in normal and tumour-bearing human liver. Cancer Immunol Immunother 2006 0.83
34 Invariant natural killer T cells from rhesus macaque spleen and peripheral blood are phenotypically and functionally distinct populations. J Med Primatol 2008 0.82
35 Protective role of regulatory decidual γδ T cells in pregnancy. Clin Immunol 2011 0.82
36 Hepatitis C virus-specific T-cell-derived transforming growth factor beta is associated with slow hepatic fibrogenesis. Hepatology 2012 0.80
37 Editorial: NKT get the 'flu: NKT cells as (mostly) good guys in influenza; monocytic cells as double agents. J Leukoc Biol 2012 0.76
38 CD1d favors MHC neighborhood, GM1 ganglioside proximity and low detergent sensitive membrane regions on the surface of B lymphocytes. Biochim Biophys Acta 2014 0.76
39 Comment on "Essential Role of IL-17A in the formation of a mycobacterial infection-induced granuloma in the lung". J Immunol 2010 0.75
40 Nuancing the proposed role of NKT cells in aging. Virulence 2011 0.75
41 Analysis of the major histocompatibility complex in graft rejection revisited by gene expression profiles. Transplantation 2004 0.75
42 Overview: NK-cell-based Immunotherapies: Toward & Into Clinical Trials. Clin Immunol 2017 0.75