José Manuel Fernández-Real

Author PubWeight™ 60.55‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile. Nat Genet 2011 2.73
2 Irisin is expressed and produced by human muscle and adipose tissue in association with obesity and insulin resistance. J Clin Endocrinol Metab 2013 2.64
3 Mirror extreme BMI phenotypes associated with gene dosage at the chromosome 16p11.2 locus. Nature 2011 2.59
4 Adipose tissue μ-crystallin is a thyroid hormone-binding protein associated with systemic insulin sensitivity. J Clin Endocrinol Metab 2014 1.96
5 Targeting the circulating microRNA signature of obesity. Clin Chem 2013 1.95
6 Profiling of circulating microRNAs reveals common microRNAs linked to type 2 diabetes that change with insulin sensitization. Diabetes Care 2014 1.86
7 Dyslipidemia and inflammation: an evolutionary conserved mechanism. Clin Nutr 2005 1.66
8 Natural antibiotics and insulin sensitivity: the role of bactericidal/permeability-increasing protein. Diabetes 2006 1.24
9 Circulating zonulin, a marker of intestinal permeability, is increased in association with obesity-associated insulin resistance. PLoS One 2012 1.23
10 Adipocytokines and insulin resistance: the possible role of lipocalin-2, retinol binding protein-4, and adiponectin. Diabetes Care 2009 1.19
11 Complement factor H is expressed in adipose tissue in association with insulin resistance. Diabetes 2009 1.19
12 Total and undercarboxylated osteocalcin predict changes in insulin sensitivity and β cell function in elderly men at high cardiovascular risk. Am J Clin Nutr 2011 1.17
13 Circulating pigment epithelium-derived factor levels are associated with insulin resistance and decrease after weight loss. J Clin Endocrinol Metab 2010 1.14
14 Circulating omentin concentration increases after weight loss. Nutr Metab (Lond) 2010 1.13
15 Circulating omentin as a novel biomarker of endothelial dysfunction. Obesity (Silver Spring) 2011 1.11
16 A role for adipocyte-derived lipopolysaccharide-binding protein in inflammation- and obesity-associated adipose tissue dysfunction. Diabetologia 2013 1.00
17 OCT1 Expression in adipocytes could contribute to increased metformin action in obese subjects. Diabetes 2010 0.98
18 The L-α-lysophosphatidylinositol/GPR55 system and its potential role in human obesity. Diabetes 2011 0.96
19 Polymorphisms in the interleukin-6 receptor gene are associated with body mass index and with characteristics of the metabolic syndrome. Clin Endocrinol (Oxf) 2006 0.96
20 Insulin resistance is associated with increased serum concentration of IGF-binding protein-related protein 1 (IGFBP-rP1/MAC25). Diabetes 2006 0.94
21 Increased levels of calprotectin in obesity are related to macrophage content: impact on inflammation and effect of weight loss. Mol Med 2011 0.94
22 Serum and urinary concentrations of calprotectin as markers of insulin resistance and type 2 diabetes. Eur J Endocrinol 2012 0.93
23 Association of circulating lactoferrin concentration and 2 nonsynonymous LTF gene polymorphisms with dyslipidemia in men depends on glucose-tolerance status. Clin Chem 2007 0.91
24 Adiponectin, hepatocellular dysfunction and insulin sensitivity. Clin Endocrinol (Oxf) 2004 0.91
25 The gut microbiota profile is associated with insulin action in humans. Acta Diabetol 2012 0.89
26 Both intrauterine growth restriction and postnatal growth influence childhood serum concentrations of adiponectin. Clin Endocrinol (Oxf) 2004 0.88
27 A polymorphism in the 3' untranslated region of the gene for tumor necrosis factor receptor 2 modulates reporter gene expression. Endocrinology 2005 0.88
28 Differential regulation of insulin action and tumor necrosis factor alpha system activity by metformin. Metabolism 2005 0.88
29 An inflammation score is better associated with basal than stimulated surrogate indexes of insulin resistance. J Clin Endocrinol Metab 2004 0.87
30 Study of lactoferrin gene expression in human and mouse adipose tissue, human preadipocytes and mouse 3T3-L1 fibroblasts. Association with adipogenic and inflammatory markers. J Nutr Biochem 2013 0.85
31 Serum lipopolysaccharide-binding protein as a marker of atherosclerosis. Atherosclerosis 2013 0.84
32 Decreased STAMP2 expression in association with visceral adipose tissue dysfunction. J Clin Endocrinol Metab 2011 0.84
33 Monocyte chemoattractant protein-1 in obesity and type 2 diabetes. Insulin sensitivity study. Obesity (Silver Spring) 2007 0.83
34 Fine-tuned iron availability is essential to achieve optimal adipocyte differentiation and mitochondrial biogenesis. Diabetologia 2014 0.82
35 The association of biomarkers of iron status with peripheral arterial disease in US adults. BMC Cardiovasc Disord 2009 0.82
36 [Impact of hormonal deficit and cardiovascular risk factors on life expectancy in hypopituitarism]. Med Clin (Barc) 2003 0.82
37 Using support vector machines to detect therapeutically incorrect measurements by the MiniMed CGMS. J Diabetes Sci Technol 2008 0.81
38 Proadipogenic effects of lactoferrin in human subcutaneous and visceral preadipocytes. J Nutr Biochem 2011 0.81
39 Insulin resistance modulates iron-related proteins in adipose tissue. Diabetes Care 2014 0.81
40 Antimicrobial-sensing proteins in obesity and type 2 diabetes: the buffering efficiency hypothesis. Diabetes Care 2011 0.81
41 Insulin-like growth factor binding protein-related protein 1 (IGFBP-rP1/MAC25) is linked to endothelial-dependent vasodilation in high-ferritin type 2 diabetes. Diabetes Care 2007 0.80
42 Decreased RB1 mRNA, protein, and activity reflect obesity-induced altered adipogenic capacity in human adipose tissue. Diabetes 2013 0.79
43 Lactoferrin gene knockdown leads to similar effects to iron chelation in human adipocytes. J Cell Mol Med 2014 0.79
44 The ACAA-insertion/deletion polymorphism at the 3' UTR of the IGF-II receptor gene is associated with type 2 diabetes and surrogate markers of insulin resistance. Eur J Endocrinol 2006 0.79
45 Role of diabetes- and obesity-related protein in the regulation of osteoblast differentiation. Am J Physiol Endocrinol Metab 2011 0.79
46 Sex-specific, independent associations of insulin resistance with erythrocyte sedimentation rate in apparently healthy subjects. Thromb Haemost 2007 0.78
47 Loss of control over eating: a description of the eating disorder/obesity spectrum in women. Eur Eat Disord Rev 2013 0.78
48 Human omental and subcutaneous adipose tissue exhibit specific lipidomic signatures. FASEB J 2013 0.78
49 The MRC1/CD68 ratio is positively associated with adipose tissue lipogenesis and with muscle mitochondrial gene expression in humans. PLoS One 2013 0.77
50 Hypothalamic damage is associated with inflammatory markers and worse cognitive performance in obese subjects. J Clin Endocrinol Metab 2014 0.77
51 Carotid pulse wave velocity by magnetic resonance imaging is increased in middle-aged subjects with the metabolic syndrome. Int J Cardiovasc Imaging 2014 0.77
52 Lipopolysaccharide-binding protein and soluble CD14 in the vitreous fluid of patients with proliferative diabetic retinopathy. Retina 2010 0.77
53 The tumour necrosis factor (TNF)-alpha-308GA promoter polymorphism is related to prenatal growth and postnatal insulin resistance. Clin Endocrinol (Oxf) 2006 0.77
54 Phosphorylated S6K1 (Thr389) is a molecular adipose tissue marker of altered glucose tolerance. J Nutr Biochem 2012 0.77
55 Circulating bactericidal/permeability-increasing protein (BPI) is associated with serum lipids and endothelial function. Thromb Haemost 2010 0.76
56 The nuclear receptor coactivator AIB3 is a modulator of HOMA beta-cell function in nondiabetic children. Clin Endocrinol (Oxf) 2008 0.76
57 Transducin-like enhancer of split 3 (TLE3) in adipose tissue is increased in situations characterized by decreased PPARγ gene expression. J Mol Med (Berl) 2014 0.76
58 Weight-loss diet alone or combined with progressive resistance training induces changes in association between the cardiometabolic risk profile and abdominal fat depots. Ann Nutr Metab 2012 0.75
59 Response to letter to the editor. J Clin Endocrinol Metab 2015 0.75
60 The possible role of antimicrobial proteins in obesity-associated immunologic alterations. Expert Rev Clin Immunol 2014 0.75
61 DBC1 is involved in adipocyte inflammation and is a possible marker of human adipose tissue senescence. Obesity (Silver Spring) 2015 0.75
62 Coxsackie and adenovirus receptor is increased in adipose tissue of obese subjects: a role for adenovirus infection? J Clin Endocrinol Metab 2014 0.75
63 Breath gas concentrations mirror exposure to sevoflurane and isopropyl alcohol in hospital environments in non-occupational conditions. J Breath Res 2016 0.75