Published in Synapse on June 01, 2007
RAGE inhibition in microglia prevents ischemia-dependent synaptic dysfunction in an amyloid-enriched environment. J Neurosci (2014) 1.47
C-terminal peptides coassemble into Abeta42 oligomers and protect neurons against Abeta42-induced neurotoxicity. Proc Natl Acad Sci U S A (2008) 1.32
Transcriptome analysis of synaptoneurosomes identifies neuroplasticity genes overexpressed in incipient Alzheimer's disease. PLoS One (2009) 1.19
Cyclophilin D deficiency rescues axonal mitochondrial transport in Alzheimer's neurons. PLoS One (2013) 1.06
Neuronal protein trafficking associated with Alzheimer disease: from APP and BACE1 to glutamate receptors. Cell Adh Migr (2009) 1.05
Abeta-dependent Inhibition of LTP in different intracortical circuits of the visual cortex: the role of RAGE. J Alzheimers Dis (2009) 0.98
Microglial receptor for advanced glycation end product-dependent signal pathway drives beta-amyloid-induced synaptic depression and long-term depression impairment in entorhinal cortex. J Neurosci (2010) 0.95
Long-Term Potentiation at CA3-CA1 Hippocampal Synapses with Special Emphasis on Aging, Disease, and Stress. Front Aging Neurosci (2011) 0.94
Reduced levels of the tyrosine phosphatase STEP block β amyloid-mediated GluA1/GluA2 receptor internalization. J Neurochem (2011) 0.93
Protection of primary neurons and mouse brain from Alzheimer's pathology by molecular tweezers. Brain (2012) 0.91
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Altered synaptic structure in the hippocampus in a mouse model of Alzheimer's disease with soluble amyloid-β oligomers and no plaque pathology. Mol Neurodegener (2014) 0.89
Calcium in the initiation, progression and as an effector of Alzheimer's disease pathology. J Cell Mol Med (2009) 0.87
Advances on the understanding of the origins of synaptic pathology in AD. Curr Genomics (2007) 0.83
Progressive effect of beta amyloid peptides accumulation on CA1 pyramidal neurons: a model study suggesting possible treatments. Front Comput Neurosci (2012) 0.81
Intrinsic excitability changes induced by acute treatment of hippocampal CA1 pyramidal neurons with exogenous amyloid β peptide. Hippocampus (2015) 0.80
Age-Dependent Modifications of AMPA Receptor Subunit Expression Levels and Related Cognitive Effects in 3xTg-AD Mice. Front Aging Neurosci (2014) 0.78
Striatal-enriched protein tyrosine phosphatase in Alzheimer's disease. Adv Pharmacol (2012) 0.77
Submicromolar Aβ42 reduces hippocampal glutamate receptors and presynaptic markers in an aggregation-dependent manner. Biochim Biophys Acta (2011) 0.76
Neuronal Cx3cr1 Deficiency Protects against Amyloid β-Induced Neurotoxicity. PLoS One (2015) 0.76
Amyloid beta toxicity dependent upon endothelial cell state. Neurosci Lett (2008) 0.76
Entorhinal Cortex dysfunction can be rescued by inhibition of microglial RAGE in an Alzheimer's disease mouse model. Sci Rep (2017) 0.75
Endophilin2 Interacts with GluA1 to Mediate AMPA Receptor Endocytosis Induced by Oligomeric Amyloid-β. Neural Plast (2017) 0.75
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy (2007) 20.92
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Amyloid beta peptides and glutamatergic synaptic dysregulation. Exp Neurol (2007) 2.08
TRPV4-mediated calcium influx into human bronchial epithelia upon exposure to diesel exhaust particles. Environ Health Perspect (2011) 1.29
Lysosomal activation is a compensatory response against protein accumulation and associated synaptopathogenesis--an approach for slowing Alzheimer disease? J Neuropathol Exp Neurol (2003) 1.18
Protective effects of positive lysosomal modulation in Alzheimer's disease transgenic mouse models. PLoS One (2011) 1.17
Ethanol modulates BKCa channels by acting as an adjuvant of calcium. Mol Pharmacol (2008) 1.14
Quantitative method for the profiling of the endocannabinoid metabolome by LC-atmospheric pressure chemical ionization-MS. Anal Chem (2007) 1.13
Substrate-selective COX-2 inhibition decreases anxiety via endocannabinoid activation. Nat Neurosci (2013) 1.11
Role of dimer interface in activation and desensitization in AMPA receptors. Proc Natl Acad Sci U S A (2010) 1.10
Potential compensatory responses through autophagic/lysosomal pathways in neurodegenerative diseases. Autophagy (2006) 1.09
Neural cell adhesion molecule-associated polysialic acid regulates synaptic plasticity and learning by restraining the signaling through GluN2B-containing NMDA receptors. J Neurosci (2010) 1.07
The second transmembrane domain of the large conductance, voltage- and calcium-gated potassium channel beta(1) subunit is a lithocholate sensor. FEBS Lett (2008) 1.06
Neuroprotective effects of the antiparkinson drug Mucuna pruriens. Phytother Res (2004) 1.05
Versatile effects of sildenafil: recent pharmacological applications. Pharmacol Rep (2007) 1.05
Cellular responses to protein accumulation involve autophagy and lysosomal enzyme activation. Rejuvenation Res (2005) 1.04
Channel beta2-4 subunits fail to substitute for beta1 in sensitizing BK channels to lithocholate. Biochem Biophys Res Commun (2009) 1.02
Enhancement of endocannabinoid signaling by fatty acid amide hydrolase inhibition: a neuroprotective therapeutic modality. Life Sci (2009) 1.01
Dual modulation of endocannabinoid transport and fatty acid amide hydrolase protects against excitotoxicity. J Neurosci (2005) 1.00
Bacopa monniera extract reduces amyloid levels in PSAPP mice. J Alzheimers Dis (2006) 0.99
Posttranslational modifications and receptor-associated proteins in AMPA receptor trafficking and synaptic plasticity. Neurosignals (2007) 0.99
Death mechanisms in status epilepticus-generated neurons and effects of additional seizures on their survival. Neurobiol Dis (2003) 0.98
Endocannabinoid enhancement protects against kainic acid-induced seizures and associated brain damage. J Pharmacol Exp Ther (2007) 0.97
Antioxidant and DNA protecting properties of anti-fatigue herb Trichopus zeylanicus. Phytother Res (2005) 0.97
Two pools of Triton X-100-insoluble GABA(A) receptors are present in the brain, one associated to lipid rafts and another one to the post-synaptic GABAergic complex. J Neurochem (2007) 0.97
Central insulin resistance and synaptic dysfunction in intracerebroventricular-streptozotocin injected rodents. Neurobiol Aging (2011) 0.96
Early necrosis and apoptosis of Schwann cells transplanted into the injured rat spinal cord. Eur J Neurosci (2007) 0.95
AMPA receptor trafficking and synaptic plasticity require SQSTM1/p62. Hippocampus (2009) 0.95
Oxidative stress and lysosomes: CNS-related consequences and implications for lysosomal enhancement strategies and induction of autophagy. Antioxid Redox Signal (2006) 0.95
Intracellular deposition, microtubule destabilization, and transport failure: an "early" pathogenic cascade leading to synaptic decline. J Neuropathol Exp Neurol (2002) 0.95
Z-Phe-Ala-diazomethylketone (PADK) disrupts and remodels early oligomer states of the Alzheimer disease Aβ42 protein. J Biol Chem (2012) 0.94
Neural cell adhesion molecule-associated polysialic acid inhibits NR2B-containing N-methyl-D-aspartate receptors and prevents glutamate-induced cell death. J Biol Chem (2006) 0.94
Loss of Thr286 phosphorylation disrupts synaptic CaMKIIα targeting, NMDAR activity and behavior in pre-adolescent mice. Mol Cell Neurosci (2011) 0.93
Neural cell adhesion molecule-associated polysialic acid potentiates alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor currents. J Biol Chem (2004) 0.93
Calpain activation is involved in early caspase-independent neurodegeneration in the hippocampus following status epilepticus. J Neurochem (2007) 0.91
Trichopus zeylanicus combats fatigue without amphetamine-mimetic activity. Phytother Res (2006) 0.91
Neurotoxic effects of methamphetamine. Neurochem Res (2009) 0.91
The critical role of calpain versus caspase activation in excitotoxic injury induced by nitric oxide. J Neurochem (2005) 0.91
Evaluation of neuroprotective and anti-fatigue effects of sildenafil. Life Sci (2007) 0.89
Methamphetamine-induced neurotoxicity: the road to Parkinson's disease. Pharmacol Rep (2010) 0.89
Blocking cannabinoid activation of FAK and ERK1/2 compromises synaptic integrity in hippocampus. Eur J Pharmacol (2005) 0.89
Smooth muscle cholesterol enables BK β1 subunit-mediated channel inhibition and subsequent vasoconstriction evoked by alcohol. Arterioscler Thromb Vasc Biol (2011) 0.89
Aniracetam reversed learning and memory deficits following prenatal ethanol exposure by modulating functions of synaptic AMPA receptors. Neuropsychopharmacology (2007) 0.88
Equipotent inhibition of fatty acid amide hydrolase and monoacylglycerol lipase - dual targets of the endocannabinoid system to protect against seizure pathology. Neurotherapeutics (2012) 0.87
Developmental nicotine exposure induced alterations in behavior and glutamate receptor function in hippocampus. Cell Mol Life Sci (2011) 0.86
3-Nitropropionic acid toxicity in hippocampus: protection through N-methyl-D-aspartate receptor antagonism. Hippocampus (2006) 0.86
Gephyrin interacts with the glutamate receptor interacting protein 1 isoforms at GABAergic synapses. J Neurochem (2008) 0.85
Proteolysis of NR2B by calpain in the hippocampus of epileptic rats. Neuroreport (2005) 0.85
Microtubule-stabilizing agent prevents protein accumulation-induced loss of synaptic markers. Eur J Pharmacol (2007) 0.85
Role of the proteasome in excitotoxicity-induced cleavage of glutamic acid decarboxylase in cultured hippocampal neurons. PLoS One (2010) 0.84
Postnatal aniracetam treatment improves prenatal ethanol induced attenuation of AMPA receptor-mediated synaptic transmission. Neurobiol Dis (2007) 0.84
Gephyrin alterations due to protein accumulation stress are reduced by the lysosomal modulator Z-Phe-Ala-diazomethylketone. J Mol Neurosci (2007) 0.84
A new generation fatty acid amide hydrolase inhibitor protects against kainate-induced excitotoxicity. J Mol Neurosci (2010) 0.84
Death effector activation in the subventricular zone subsequent to perinatal hypoxia/ischemia. J Neurochem (2007) 0.83
Selective cholinergic depletion in medial septum leads to impaired long term potentiation and glutamatergic synaptic currents in the hippocampus. PLoS One (2012) 0.83
Involvement of calpain in AMPA-induced toxicity to rat cerebellar Purkinje neurons. Eur J Pharmacol (2006) 0.83
Sulfate- and size-dependent polysaccharide modulation of AMPA receptor properties. J Neurosci Res (2004) 0.83
Purkinje neuron Ca2+ influx reduction rescues ataxia in SCA28 model. J Clin Invest (2014) 0.82
Single channel recordings from synaptosomal AMPA receptors. Cell Biochem Biophys (2005) 0.82
Paraquat and maneb induced neurotoxicity. Proc West Pharmacol Soc (2007) 0.82
Early calpain-mediated proteolysis following AMPA receptor activation compromises neuronal survival in cultured hippocampal neurons. J Neurochem (2004) 0.81
Enhancement of odorant-induced responses in olfactory receptor neurons by zinc nanoparticles. Chem Senses (2009) 0.81
Memory impairments and hippocampal modifications in adult rats with neonatal isolation stress experience. Neurobiol Learn Mem (2007) 0.81
Effect of antiparkinson drug HP-200 (Mucuna pruriens) on the central monoaminergic neurotransmitters. Phytother Res (2004) 0.80
Quantitative proteomics analysis of CaMKII phosphorylation and the CaMKII interactome in the mouse forebrain. ACS Chem Neurosci (2015) 0.80
Cardiovascular effects of transdermally delivered bupranolol in rabbits: effect of chemical penetration enhancers. Life Sci (2007) 0.80
Lysosomal dysfunction produces distinct alterations in synaptic alpha-amino-3-hydroxy-5-methylisoxazolepropionic acid and N-methyl-D-aspartate receptor currents in hippocampus. J Neuropathol Exp Neurol (2007) 0.80
Calcium influx and calpain activation mediate preclinical retinal neurodegeneration in autoimmune optic neuritis. J Neuropathol Exp Neurol (2013) 0.80
Biphasic NF-kappaB activation in the excitotoxic hippocampus. Acta Neuropathol (2004) 0.79
Cannabinoid drugs and enhancement of endocannabinoid responses: strategies for a wide array of disease states. Curr Mol Med (2006) 0.79
Modulatory effects of dextran sulfate and fucoidan on binding and channel properties of AMPA receptors isolated from rat brain. Synapse (2006) 0.79
Cleavage of the vesicular glutamate transporters under excitotoxic conditions. Neurobiol Dis (2011) 0.78
Nuclear translocation and calpain-dependent reduction of Bcl-2 after neonatal cerebral hypoxia-ischemia. Brain Behav Immun (2009) 0.78
Ameliorating effects of preadolescent aniracetam treatment on prenatal ethanol-induced impairment in AMPA receptor activity. Neurobiol Dis (2007) 0.78
Melatonin synergizes with low doses of L-DOPA to improve dendritic spine density in the mouse striatum in experimental Parkinsonism. J Pineal Res (2013) 0.78
Antioxidant-mediated reversal of oxidative damage in mouse modeling of complex I inhibition. Drug Dev Res (2015) 0.77