Published in Annu Rev Neurosci on January 01, 2007
Cortico-Basal Ganglia reward network: microcircuitry. Neuropsychopharmacology (2010) 3.81
Recombinase-driver rat lines: tools, techniques, and optogenetic application to dopamine-mediated reinforcement. Neuron (2011) 3.49
Affective neuroscience of pleasure: reward in humans and animals. Psychopharmacology (Berl) (2008) 3.26
The mysterious motivational functions of mesolimbic dopamine. Neuron (2012) 3.22
Predicting value of pain and analgesia: nucleus accumbens response to noxious stimuli changes in the presence of chronic pain. Neuron (2010) 3.11
Distinct extended amygdala circuits for divergent motivational states. Nature (2013) 2.88
Dopamine neurons modulate neural encoding and expression of depression-related behaviour. Nature (2012) 2.88
Activation of VTA GABA neurons disrupts reward consumption. Neuron (2012) 2.80
Cocaine but not natural reward self-administration nor passive cocaine infusion produces persistent LTP in the VTA. Neuron (2008) 2.69
A causal link between prediction errors, dopamine neurons and learning. Nat Neurosci (2013) 2.68
Dissociable cost and benefit encoding of future rewards by mesolimbic dopamine. Nat Neurosci (2009) 2.29
Synaptic overflow of dopamine in the nucleus accumbens arises from neuronal activity in the ventral tegmental area. J Neurosci (2009) 2.16
The role of dopamine in the accumbens core in the expression of Pavlovian-conditioned responses. Eur J Neurosci (2012) 1.94
Serotonin and dopamine: unifying affective, activational, and decision functions. Neuropsychopharmacology (2010) 1.87
Shape shifting pain: chronification of back pain shifts brain representation from nociceptive to emotional circuits. Brain (2013) 1.77
Activation of D1 dopamine receptors induces emergence from isoflurane general anesthesia. Anesthesiology (2013) 1.69
AMPA receptor synaptic plasticity induced by psychostimulants: the past, present, and therapeutic future. Neuron (2010) 1.68
A pair of dopamine neurons target the D1-like dopamine receptor DopR in the central complex to promote ethanol-stimulated locomotion in Drosophila. PLoS One (2010) 1.68
Reward and aversion in a heterogeneous midbrain dopamine system. Neuropharmacology (2013) 1.67
Pacemaking in dopaminergic ventral tegmental area neurons: depolarizing drive from background and voltage-dependent sodium conductances. J Neurosci (2010) 1.66
Circuit Architecture of VTA Dopamine Neurons Revealed by Systematic Input-Output Mapping. Cell (2015) 1.64
Decoding neural circuits that control compulsive sucrose seeking. Cell (2015) 1.61
The inhibitory influence of the lateral habenula on midbrain dopamine cells: ultrastructural evidence for indirect mediation via the rostromedial mesopontine tegmental nucleus. J Comp Neurol (2011) 1.59
Sleep deprivation amplifies reactivity of brain reward networks, biasing the appraisal of positive emotional experiences. J Neurosci (2011) 1.58
Ventral tegmental area glutamate neurons: electrophysiological properties and projections. J Neurosci (2012) 1.57
Diversity of transgenic mouse models for selective targeting of midbrain dopamine neurons. Neuron (2015) 1.47
Persistent Adaptations in Afferents to Ventral Tegmental Dopamine Neurons after Opiate Withdrawal. J Neurosci (2015) 1.47
The flexible approach hypothesis: unification of effort and cue-responding hypotheses for the role of nucleus accumbens dopamine in the activation of reward-seeking behavior. J Neurosci (2010) 1.45
Pain relief produces negative reinforcement through activation of mesolimbic reward-valuation circuitry. Proc Natl Acad Sci U S A (2012) 1.44
Dorsomedial prefrontal cortex contribution to behavioral and nucleus accumbens neuronal responses to incentive cues. J Neurosci (2008) 1.44
Designer receptors show role for ventral pallidum input to ventral tegmental area in cocaine seeking. Nat Neurosci (2014) 1.40
Activation of Pedunculopontine Glutamate Neurons Is Reinforcing. J Neurosci (2017) 1.40
Convergent processing of both positive and negative motivational signals by the VTA dopamine neuronal populations. PLoS One (2011) 1.36
Voluntary ethanol intake enhances excitatory synaptic strength in the ventral tegmental area. Alcohol Clin Exp Res (2008) 1.29
Cocaine-induced plasticity in the nucleus accumbens is cell specific and develops without prolonged withdrawal. J Neurosci (2011) 1.28
Roles of nucleus accumbens core and shell in incentive-cue responding and behavioral inhibition. J Neurosci (2011) 1.28
DNA methylation regulates associative reward learning. Nat Neurosci (2013) 1.27
Hypothalamic neurotensin projections promote reward by enhancing glutamate transmission in the VTA. J Neurosci (2013) 1.26
Prominent activation of brainstem and pallidal afferents of the ventral tegmental area by cocaine. Neuropsychopharmacology (2007) 1.23
Contributions of the amygdala and medial prefrontal cortex to incentive cue responding. Neuroscience (2008) 1.23
κ-opioid receptors are implicated in the increased potency of intra-accumbens nalmefene in ethanol-dependent rats. Neuropharmacology (2011) 1.23
Neuronal circuits underlying acute morphine action on dopamine neurons. Proc Natl Acad Sci U S A (2011) 1.23
Effective connectivity of a reward network in obese women. Brain Res Bull (2009) 1.23
Dorsolateral prefrontal cortex drives mesolimbic dopaminergic regions to initiate motivated behavior. J Neurosci (2011) 1.22
Individual variation in resisting temptation: implications for addiction. Neurosci Biobehav Rev (2013) 1.21
Contextual novelty changes reward representations in the striatum. J Neurosci (2010) 1.20
GABAergic and glutamatergic efferents of the mouse ventral tegmental area. J Comp Neurol (2014) 1.19
Role of the bed nucleus of the stria terminalis in the control of ventral tegmental area dopamine neurons. Prog Neuropsychopharmacol Biol Psychiatry (2009) 1.15
Encoding of aversion by dopamine and the nucleus accumbens. Front Neurosci (2012) 1.13
Targeting dynorphin/kappa opioid receptor systems to treat alcohol abuse and dependence. Alcohol (2012) 1.12
Chronic cocaine enhances corticotropin-releasing factor-dependent potentiation of excitatory transmission in ventral tegmental area dopamine neurons. J Neurosci (2009) 1.11
Transient activation of specific neurons in mice by selective expression of the capsaicin receptor. Nat Commun (2012) 1.10
Neuronal nicotinic acetylcholine receptors: common molecular substrates of nicotine and alcohol dependence. Front Psychiatry (2013) 1.10
Optogenetic modulation of neural circuits that underlie reward seeking. Biol Psychiatry (2011) 1.09
Dopamine neurons control striatal cholinergic neurons via regionally heterogeneous dopamine and glutamate signaling. Neuron (2014) 1.08
Contextual interaction between novelty and reward processing within the mesolimbic system. Hum Brain Mapp (2011) 1.07
The basal ganglia is necessary for learning spectral, but not temporal, features of birdsong. Neuron (2013) 1.07
New insights into the specificity and plasticity of reward and aversion encoding in the mesolimbic system. J Neurosci (2013) 1.07
An update on the connections of the ventral mesencephalic dopaminergic complex. Neuroscience (2014) 1.06
Optogenetic dissection of neural circuits underlying emotional valence and motivated behaviors. Brain Res (2012) 1.06
AMPA receptor subunit GluR1 downstream of D-1 dopamine receptor stimulation in nucleus accumbens shell mediates increased drug reward magnitude in food-restricted rats. Neuroscience (2009) 1.06
Peroxisome proliferator-activated receptors-alpha modulate dopamine cell activity through nicotinic receptors. Biol Psychiatry (2010) 1.05
Positive reinforcement mediated by midbrain dopamine neurons requires D1 and D2 receptor activation in the nucleus accumbens. PLoS One (2014) 1.04
Electrical stimulation of the ventral tegmental area induces reanimation from general anesthesia. Anesthesiology (2014) 1.03
Pain and Poppies: The Good, the Bad, and the Ugly of Opioid Analgesics. J Neurosci (2015) 1.03
VTA GABA neurons modulate specific learning behaviors through the control of dopamine and cholinergic systems. Front Behav Neurosci (2014) 1.02
The Potent Effect of Environmental Context on Relapse to Alcohol-Seeking After Extinction. Open Addict J (2010) 1.00
Increased Fos expression among midbrain dopaminergic cell groups during birdsong tutoring. Eur J Neurosci (2009) 0.99
Melanocortin 4 receptor signaling in dopamine 1 receptor neurons is required for procedural memory learning. Physiol Behav (2012) 0.99
Stress and VTA synapses: implications for addiction and depression. Eur J Neurosci (2014) 0.99
Computational models of reinforcement learning: the role of dopamine as a reward signal. Cogn Neurodyn (2010) 0.98
Social modulation during songbird courtship potentiates midbrain dopaminergic neurons. PLoS One (2008) 0.98
Parceling human accumbens into putative core and shell dissociates encoding of values for reward and pain. J Neurosci (2013) 0.96
Establishing causality for dopamine in neural function and behavior with optogenetics. Brain Res (2012) 0.96
Mesolimbic dopamine dynamically tracks, and is causally linked to, discrete aspects of value-based decision making. Biol Psychiatry (2014) 0.95
Alcohol-induced plasticity in the dynorphin/kappa-opioid receptor system. Front Mol Neurosci (2012) 0.95
Stress induced obesity: lessons from rodent models of stress. Front Neurosci (2013) 0.93
Conjunctive encoding of movement and reward by ventral tegmental area neurons in the freely navigating rodent. Behav Neurosci (2010) 0.93
Understanding opioid reward. Trends Neurosci (2015) 0.93
Long-term memory for pavlovian fear conditioning requires dopamine in the nucleus accumbens and basolateral amygdala. PLoS One (2010) 0.93
An empirical review of the neural underpinnings of receiving and giving social support: implications for health. Psychosom Med (2013) 0.92
Effects of prefrontal cortical inactivation on neural activity in the ventral tegmental area. J Neurosci (2013) 0.92
Opioid modulation of ventral pallidal afferents to ventral tegmental area neurons. J Neurosci (2013) 0.92
Does the kappa opioid receptor system contribute to pain aversion? Front Pharmacol (2014) 0.92
Post-training cocaine exposure facilitates spatial memory consolidation in C57BL/6 mice. Hippocampus (2011) 0.89
Mefloquine effects on ventral tegmental area dopamine and GABA neuron inhibition: a physiologic role for connexin-36 GAP junctions. Synapse (2011) 0.89
FoxP2 brainstem neurons project to sodium appetite regulatory sites. J Chem Neuroanat (2011) 0.89
Oxytocin action in the ventral tegmental area affects sucrose intake. Brain Res (2013) 0.89
Hub and switches: endocannabinoid signalling in midbrain dopamine neurons. Philos Trans R Soc Lond B Biol Sci (2012) 0.89
Corticotropin Releasing Factor Binding Protein and CRF2 Receptors in the Ventral Tegmental Area: Modulation of Ethanol Binge Drinking in C57BL/6J Mice. Alcohol Clin Exp Res (2015) 0.89
Transient inactivation of the ventral tegmental area selectively disrupts the expression of conditioned place preference for pup- but not cocaine-paired contexts. Behav Neurosci (2009) 0.88
Sucrose self-administration and CNS activation in the rat. Am J Physiol Regul Integr Comp Physiol (2011) 0.88
Role of nucleus accumbens dopamine receptor subtypes in the learning and expression of alcohol-seeking behavior. Neurobiol Learn Mem (2013) 0.88
Poststress block of kappa opioid receptors rescues long-term potentiation of inhibitory synapses and prevents reinstatement of cocaine seeking. Biol Psychiatry (2014) 0.88
Strain specific synaptic modifications on ventral tegmental area dopamine neurons after ethanol exposure. Biol Psychiatry (2008) 0.87
The vital role of constitutive GPCR activity in the mesolimbic dopamine system. Transl Psychiatry (2014) 0.87
Functional mapping of the neural circuitry of rat maternal motivation: effects of site-specific transient neural inactivation. J Neuroendocrinol (2011) 0.87
Sources of input to the rostromedial tegmental nucleus, ventral tegmental area, and lateral habenula compared: A study in rat. J Comp Neurol (2015) 0.86
Distinct prestimulus and poststimulus activation of VTA neurons correlates with stimulus detection. J Neurophysiol (2013) 0.86
It's MORe exciting than mu: crosstalk between mu opioid receptors and glutamatergic transmission in the mesolimbic dopamine system. Front Pharmacol (2014) 0.86
The ventral tegmental area revisited: is there an electrophysiological marker for dopaminergic neurons? J Physiol (2006) 3.97
Basolateral amygdala neurons facilitate reward-seeking behavior by exciting nucleus accumbens neurons. Neuron (2008) 2.77
Kappa opioids selectively control dopaminergic neurons projecting to the prefrontal cortex. Proc Natl Acad Sci U S A (2006) 2.29
Midbrain dopamine neurons: projection target determines action potential duration and dopamine D(2) receptor inhibition. J Neurosci (2008) 2.28
Kappa-opioid agonists directly inhibit midbrain dopaminergic neurons. J Neurosci (2003) 2.21
The ventral tegmental area is required for the behavioral and nucleus accumbens neuronal firing responses to incentive cues. J Neurosci (2004) 1.97
Glutamatergic and nonglutamatergic neurons of the ventral tegmental area establish local synaptic contacts with dopaminergic and nondopaminergic neurons. J Neurosci (2010) 1.82
Invigoration of reward seeking by cue and proximity encoding in the nucleus accumbens. Neuron (2013) 1.71
Both kappa and mu opioid agonists inhibit glutamatergic input to ventral tegmental area neurons. J Neurophysiol (2004) 1.62
Ventral tegmental area glutamate neurons: electrophysiological properties and projections. J Neurosci (2012) 1.57
Dorsomedial prefrontal cortex contribution to behavioral and nucleus accumbens neuronal responses to incentive cues. J Neurosci (2008) 1.44
Contrasting effects of dopamine and glutamate receptor antagonist injection in the nucleus accumbens suggest a neural mechanism underlying cue-evoked goal-directed behavior. Eur J Neurosci (2004) 1.38
Nucleus accumbens medium spiny neurons target non-dopaminergic neurons in the ventral tegmental area. J Neurosci (2011) 1.34
Roles of nucleus accumbens core and shell in incentive-cue responding and behavioral inhibition. J Neurosci (2011) 1.28
Delta-opioid receptor expression in the ventral tegmental area protects against elevated alcohol consumption. J Neurosci (2008) 1.24
Contrast enhancement: a physiological effect of striatal dopamine? Cell Tissue Res (2004) 1.12
Cue-evoked encoding of movement planning and execution in the rat nucleus accumbens. J Physiol (2007) 1.08
New insights into the specificity and plasticity of reward and aversion encoding in the mesolimbic system. J Neurosci (2013) 1.07
Dissociation of the role of nucleus accumbens dopamine in responding to reward-predictive cues and waiting for reward. Behav Brain Res (2004) 1.02
A single cocaine exposure enhances both opioid reward and aversion through a ventral tegmental area-dependent mechanism. Proc Natl Acad Sci U S A (2004) 0.94
An inexpensive drivable cannulated microelectrode array for simultaneous unit recording and drug infusion in the same brain nucleus of behaving rats. J Neurophysiol (2011) 0.94
Opioid modulation of ventral pallidal afferents to ventral tegmental area neurons. J Neurosci (2013) 0.92
Acute amphetamine exposure selectively desensitizes kappa-opioid receptors in the nucleus accumbens. Neuropsychopharmacology (2007) 0.86
Intra-VTA deltorphin, but not DPDPE, induces place preference in ethanol-drinking rats: distinct DOR-1 and DOR-2 mechanisms control ethanol consumption and reward. Alcohol Clin Exp Res (2013) 0.82
A novel opioid receptor-mediated enhancement of GABAA receptor function induced by stress in ventral tegmental area neurons. J Physiol (2011) 0.81
Substance P inhibits GABAB receptor signalling in the ventral tegmental area. J Physiol (2010) 0.81
Intermittent access to sweet high-fat liquid induces increased palatability and motivation to consume in a rat model of binge consumption. Physiol Behav (2013) 0.77
Alcohol self-administration, anxiety, and cortisol levels predict changes in delta opioid receptor function in the ventral tegmental area. Behav Neurosci (2012) 0.76
Protein kinase inhibitors reduce GABA but not glutamate release in the nucleus accumbens. Neuropharmacology (2007) 0.75