John W McAvoy

Author PubWeight™ 32.26‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A role for Wnt/beta-catenin signaling in lens epithelial differentiation. Dev Biol 2003 1.39
2 TGFbeta induces morphological and molecular changes similar to human anterior subcapsular cataract. Br J Ophthalmol 2002 1.25
3 Wnt signaling is required for organization of the lens fiber cell cytoskeleton and development of lens three-dimensional architecture. Dev Biol 2008 1.21
4 Characterization of a familial t(16;22) balanced translocation associated with congenital cataract leads to identification of a novel gene, TMEM114, expressed in the lens and disrupted by the translocation. Hum Mutat 2007 1.21
5 Duration of ERK1/2 phosphorylation induced by FGF or ocular media determines lens cell fate. Differentiation 2007 1.13
6 Nance-Horan syndrome protein, NHS, associates with epithelial cell junctions. Hum Mol Genet 2006 1.11
7 Secreted frizzled-related protein disrupts PCP in eye lens fiber cells that have polarised primary cilia. Dev Biol 2009 1.08
8 Aqueous humour- and growth factor-induced lens cell proliferation is dependent on MAPK/ERK1/2 and Akt/PI3-K signalling. Exp Eye Res 2006 1.05
9 Expression of Frizzleds and secreted frizzled-related proteins (Sfrps) during mammalian lens development. Int J Dev Biol 2004 1.04
10 Aberrant lens fiber differentiation in anterior subcapsular cataract formation: a process dependent on reduced levels of Pax6. Invest Ophthalmol Vis Sci 2004 1.02
11 MAPK/ERK1/2 and PI3-kinase signalling pathways are required for vitreous-induced lens fibre cell differentiation. Exp Eye Res 2008 1.00
12 Growth factors involved in aqueous humour-induced lens cell proliferation. Growth Factors 2009 1.00
13 Crim1KST264/KST264 mice display a disruption of the Crim1 gene resulting in perinatal lethality with defects in multiple organ systems. Dev Dyn 2007 0.99
14 Fibroblast growth factor 2: roles of regulation of lens cell proliferation and epithelial-mesenchymal transition in response to injury. Mol Vis 2004 0.98
15 Influence of platelet-derived growth factor on lens epithelial cell proliferation and differentiation. Growth Factors 2002 0.96
16 Planar cell polarity in the mammalian eye lens. Organogenesis 2011 0.95
17 Sprouty is a negative regulator of transforming growth factor β-induced epithelial-to-mesenchymal transition and cataract. Mol Med 2012 0.95
18 Growth factor signaling in vitreous humor-induced lens fiber differentiation. Invest Ophthalmol Vis Sci 2010 0.92
19 BMP and activin receptor expression in lens development. Mol Vis 2004 0.90
20 Sef and Sprouty expression in the developing ocular lens: implications for regulating lens cell proliferation and differentiation. Semin Cell Dev Biol 2006 0.89
21 Apoptosis is a feature of TGF beta-induced cataract. Clin Exp Optom 2002 0.88
22 In vitro generation of functional lens-like structures with relevance to age-related nuclear cataract. Invest Ophthalmol Vis Sci 2007 0.86
23 Laminin-binding integrins in rat lens morphogenesis and their regulation during fibre differentiation. Exp Eye Res 2005 0.86
24 Wnt-frizzled signaling is part of an FGF-induced cascade that promotes lens fiber differentiation. Invest Ophthalmol Vis Sci 2013 0.84
25 Vitronectin is present in epithelial cells of the intact lens and promotes epithelial mesenchymal transition in lens epithelial explants. Mol Vis 2006 0.84
26 Generation of transparency and cellular organization in lens explants. Exp Eye Res 2008 0.84
27 The fate of dividing cells during lens morphogenesis, differentiation and growth. Exp Eye Res 2011 0.83
28 NHS-A isoform of the NHS gene is a novel interactor of ZO-1. Exp Cell Res 2009 0.83
29 Using soybean trypsin inhibitor as an external loading control for Western blot analysis of tear proteins: application to corneal disease. Exp Eye Res 2012 0.82
30 Analysis of PCP defects in mammalian eye lens. Methods Mol Biol 2012 0.81
31 Tear levels of SFRP1 are significantly reduced in keratoconus patients. Mol Vis 2013 0.81
32 Sfrp1 and Sfrp2 are not involved in Wnt/β-catenin signal silencing during lens induction but are required for maintenance of Wnt/β-catenin signaling in lens epithelial cells. Dev Biol 2013 0.78
33 Sef is a negative regulator of fiber cell differentiation in the ocular lens. Differentiation 2010 0.78
34 Dexamethasone influences FGF-induced responses in lens epithelial explants and promotes the posterior capsule coverage that is a feature of glucocorticoid-induced cataract. Exp Eye Res 2013 0.75