DNA damage, p53, apoptosis and vascular disease.

PubWeight™: 1.15‹?› | Rank: Top 10%

🔗 View Article (PMID 17382357)

Published in Mutat Res on March 01, 2007

Authors

John Mercer1, Melli Mahmoudi, Martin Bennett

Author Affiliations

1: Division of Cardiovascular Medicine, University of Cambridge, P.O. Box 110, Addenbrooke's Hospital, Cambridge CB2 2QQ, United Kingdom.

Articles citing this

The DNA-damage response in human biology and disease. Nature (2009) 17.86

Molecular mechanisms of ultraviolet radiation-induced DNA damage and repair. J Nucleic Acids (2010) 1.91

Do non-targeted effects increase or decrease low dose risk in relation to the linear-non-threshold (LNT) model? Mutat Res (2010) 0.87

Effects of Aging and Hypercholesterolemia on Oxidative Stress and DNA Damage in Bone Marrow Mononuclear Cells in Apolipoprotein E-deficient Mice. Int J Mol Sci (2013) 0.86

A comparison of replicative senescence and doxorubicin-induced premature senescence of vascular smooth muscle cells isolated from human aorta. Biogerontology (2013) 0.84

Oxidative damage markers are significantly associated with the carotid artery intima-media thickness after controlling for conventional risk factors of atherosclerosis in men. PLoS One (2015) 0.82

Renovascular hypertension leads to DNA damage and apoptosis in bone marrow cells. DNA Cell Biol (2013) 0.82

Short-term Mg deficiency upregulates protein kinase C isoforms in cardiovascular tissues and cells; relation to NF-kB, cytokines, ceramide salvage sphingolipid pathway and PKC-zeta: hypothesis and review. Int J Clin Exp Med (2014) 0.81

Short-term magnesium deficiency upregulates sphingomyelin synthase and p53 in cardiovascular tissues and cells: relevance to the de novo synthesis of ceramide. Am J Physiol Heart Circ Physiol (2010) 0.80

Genomic damage in endstage renal disease-contribution of uremic toxins. Toxins (Basel) (2010) 0.79

Short-term magnesium deficiency downregulates telomerase, upregulates neutral sphingomyelinase and induces oxidative DNA damage in cardiovascular tissues: relevance to atherogenesis, cardiovascular diseases and aging. Int J Clin Exp Med (2014) 0.79

Gene expression profiling of peripheral blood mononuclear cells in the setting of peripheral arterial disease. J Clin Bioinforma (2012) 0.79

Genetic damage in patients with chronic kidney disease, peritoneal dialysis and haemodialysis: a comparative study. Mutagenesis (2013) 0.78

Transcriptome and Molecular Endocrinology Aspects of Epicardial Adipose Tissue in Cardiovascular Diseases: A Systematic Review and Meta-Analysis of Observational Studies. Biomed Res Int (2015) 0.78

miR-100 antagonism triggers apoptosis by inhibiting ubiquitination-mediated p53 degradation. Oncogene (2016) 0.77

Urinary levels of 8-iso-prostaglandin f2α and 8-hydroxydeoxyguanine as markers of oxidative stress in patients with coronary artery disease. Korean Circ J (2012) 0.77

Role of Long Noncoding RNA HOTAIR in the Growth and Apoptosis of Osteosarcoma Cell MG-63. Biomed Res Int (2016) 0.77

Disturbed flow: p53 SUMOylation in the turnover of endothelial cells. J Cell Biol (2011) 0.76

DNA Damage in Chronic Kidney Disease: Evaluation of Clinical Biomarkers. Oxid Med Cell Longev (2016) 0.75

Cardiovascular diseases related to ionizing radiation: The risk of low-dose exposure (Review). Int J Mol Med (2016) 0.75

Articles by these authors

Monocyte/macrophage suppression in CD11b diphtheria toxin receptor transgenic mice differentially affects atherogenesis and established plaques. Circ Res (2007) 2.74

Vascular smooth muscle cells undergo telomere-based senescence in human atherosclerosis: effects of telomerase and oxidative stress. Circ Res (2006) 2.58

Aging and atherosclerosis: mechanisms, functional consequences, and potential therapeutics for cellular senescence. Circ Res (2012) 2.14

Bone marrow-derived smooth muscle-like cells are infrequent in advanced primary atherosclerotic plaques but promote atherosclerosis. Arterioscler Thromb Vasc Biol (2011) 1.55

Surgical repair of truncus arteriosus associated with interrupted aortic arch: long-term outcomes. Ann Thorac Surg (2011) 1.54

Impact of cellular senescence signature on ageing research. Ageing Res Rev (2010) 1.47

DNA damage links mitochondrial dysfunction to atherosclerosis and the metabolic syndrome. Circ Res (2010) 1.36

Vascular smooth muscle cell senescence in atherosclerosis. Cardiovasc Res (2006) 1.36

The emerging role of vascular smooth muscle cell apoptosis in atherosclerosis and plaque stability. Am J Nephrol (2006) 1.33

Vascular smooth muscle cell sirtuin 1 protects against DNA damage and inhibits atherosclerosis. Circulation (2012) 1.23

DNA damage and repair in atherosclerosis. Cardiovasc Res (2006) 1.07

Mitochondria in vascular disease. Cardiovasc Res (2012) 1.06

Statins use a novel Nijmegen breakage syndrome-1-dependent pathway to accelerate DNA repair in vascular smooth muscle cells. Circ Res (2008) 1.04

Hyperbaric oxygenation in the management of cerebral arterial gas embolism during cavopulmonary connection surgery. J Cardiothorac Vasc Anesth (2007) 1.04

The role of p53 in atherosclerosis. Cell Cycle (2006) 0.99

Interferon-gamma induces Fas trafficking and sensitization to apoptosis in vascular smooth muscle cells via a PI3K- and Akt-dependent mechanism. Am J Pathol (2006) 0.99

Nutrient deprivation regulates DNA damage repair in cardiomyocytes via loss of the base-excision repair enzyme OGG1. FASEB J (2012) 0.94

Progenitor cell-derived smooth muscle cells in vascular disease. Biochem Pharmacol (2010) 0.93

Role of DNA damage in atherosclerosis--bystander or participant? Biochem Pharmacol (2011) 0.93

Differential gene expression in vascular smooth muscle cells in primary atherosclerosis and in stent stenosis in humans. Arterioscler Thromb Vasc Biol (2002) 0.92

Defining the role of vascular smooth muscle cell apoptosis in atherosclerosis. Cell Cycle (2006) 0.91

High-throughput sequencing identifies STAT3 as the DNA-associated factor for p53-NF-kappaB-complex-dependent gene expression in human heart failure. Genome Med (2010) 0.90

Cell death in the cardiovascular system. Heart (2006) 0.89

Ageing and atherosclerosis: Mechanisms and therapeutic options. Biochem Pharmacol (2007) 0.89

Rapamycin inhibits human in stent restenosis vascular smooth muscle cells independently of pRB phosphorylation and p53. Cardiovasc Res (2005) 0.84

Monitoring Unfractionated Heparin (UFH) therapy: which Anti-Factor Xa assay is appropriate? Thromb Res (2006) 0.83

Centrifugal pump inlet pressure site affects measurement. Perfusion (2010) 0.82

Cell death and survival signalling in the cardiovascular system. Front Biosci (Landmark Ed) (2012) 0.78

Extracorporeal membrane oxygenation via sternotomy for circulatory shock. J Thorac Cardiovasc Surg (2008) 0.77

Poor maternal nutrition programmes a pro-atherosclerotic phenotype in ApoE-/- mice. Clin Sci (Lond) (2012) 0.76

Assessment and consequences of cell senescence in atherosclerosis. Curr Opin Lipidol (2016) 0.75

New technology increases perioperative haemoglobin levels for paediatric cardiopulmonary bypass: what is the benefit? Perfusion (2006) 0.75

The use of extracorporeal life support in the treatment of influenza-associated myositis/rhabdomyolysis. Perfusion (2006) 0.75

Long-distance transport of critically ill children on extracorporeal life support in Australia. Crit Care Resusc (2008) 0.75

Complications of extra-anatomic aortic bypass for complex coarctation and aortic arch hypoplasia. Ann Thorac Surg (2012) 0.75