PubRank

J Marie Hardwick

Author PubWeight™ 62.26‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Mitochondrial fission proteins regulate programmed cell death in yeast. Genes Dev 2004 2.30
2 Calpain I induces cleavage and release of apoptosis-inducing factor from isolated mitochondria. J Biol Chem 2004 2.17
3 Bcl-xL induces Drp1-dependent synapse formation in cultured hippocampal neurons. Proc Natl Acad Sci U S A 2008 2.17
4 Bax-type apoptotic proteins porate pure lipid bilayers through a mechanism sensitive to intrinsic monolayer curvature. J Biol Chem 2002 2.00
5 Bcl-x L increases mitochondrial fission, fusion, and biomass in neurons. J Cell Biol 2009 1.97
6 Bcl-xL regulates metabolic efficiency of neurons through interaction with the mitochondrial F1FO ATP synthase. Nat Cell Biol 2011 1.76
7 Genome-wide consequences of deleting any single gene. Mol Cell 2013 1.76
8 Enhancing DNA vaccine potency by coadministration of DNA encoding antiapoptotic proteins. J Clin Invest 2003 1.71
9 Upgrading the BCL-2 network. Nat Cell Biol 2006 1.59
10 BAK alters neuronal excitability and can switch from anti- to pro-death function during postnatal development. Dev Cell 2003 1.56
11 Bcl-xL regulates mitochondrial energetics by stabilizing the inner membrane potential. J Cell Biol 2011 1.52
12 Cytosolic domain of the human mitochondrial fission protein fis1 adopts a TPR fold. Proteins 2004 1.39
13 N-terminally cleaved Bcl-xL mediates ischemia-induced neuronal death. Nat Neurosci 2012 1.36
14 Inhibition of translation and induction of apoptosis by Bunyaviral nonstructural proteins bearing sequence similarity to reaper. Mol Biol Cell 2003 1.32
15 Modification of professional antigen-presenting cells with small interfering RNA in vivo to enhance cancer vaccine potency. Cancer Res 2005 1.32
16 Bcl-xL inhibitor ABT-737 reveals a dual role for Bcl-xL in synaptic transmission. J Neurophysiol 2007 1.29
17 Modulation of synaptic transmission by the BCL-2 family protein BCL-xL. J Neurosci 2003 1.28
18 Proapoptotic N-truncated BCL-xL protein activates endogenous mitochondrial channels in living synaptic terminals. Proc Natl Acad Sci U S A 2004 1.27
19 Anti-apoptotic Bcl-2 Family Proteins Disassemble Ceramide Channels. J Biol Chem 2008 1.24
20 Enhancing DNA vaccine potency by combining a strategy to prolong dendritic cell life with intracellular targeting strategies. J Immunol 2003 1.21
21 Zinc-dependent multi-conductance channel activity in mitochondria isolated from ischemic brain. J Neurosci 2006 1.19
22 Viruses activate a genetically conserved cell death pathway in a unicellular organism. J Cell Biol 2005 1.15
23 Viral Bcl-2 homologs and their role in virus replication and associated diseases. Biochim Biophys Acta 2004 1.14
24 Aven-dependent activation of ATM following DNA damage. Curr Biol 2008 1.08
25 Evolution of Bcl-2 homology motifs: homology versus homoplasy. Trends Cell Biol 2012 1.08
26 Inhibitor specificity of recombinant and endogenous caspase-9. Biochem J 2002 1.07
27 Mitochondrial involvement in cell death of non-mammalian eukaryotes. Biochim Biophys Acta 2010 1.07
28 Epstein-Barr virus BALF1 is a BCL-2-like antagonist of the herpesvirus antiapoptotic BCL-2 proteins. J Virol 2002 1.05
29 Mitochondrial death pathways in yeast and mammalian cells. Biochim Biophys Acta 2008 1.04
30 The mTOR inhibitor rapamycin has limited acute anticonvulsant effects in mice. PLoS One 2012 1.01
31 Magnetic resonance diffusion tensor microimaging reveals a role for Bcl-x in brain development and homeostasis. J Neurosci 2005 0.99
32 BCL-2 and BAX protect adult mice from lethal Sindbis virus infection but do not protect spinal cord motor neurons or prevent paralysis. J Virol 2002 0.99
33 BAD is a pro-survival factor prior to activation of its pro-apoptotic function. J Biol Chem 2004 0.94
34 A new view of the lethal apoptotic pore. PLoS Biol 2012 0.94
35 Aven and Bcl-xL enhance protection against apoptosis for mammalian cells exposed to various culture conditions. Biotechnol Bioeng 2004 0.93
36 Actions of BAX on mitochondrial channel activity and on synaptic transmission. Antioxid Redox Signal 2005 0.93
37 Exposure to hypoxia rapidly induces mitochondrial channel activity within a living synapse. J Biol Chem 2004 0.92
38 Seizure tests distinguish intermittent fasting from the ketogenic diet. Epilepsia 2010 0.92
39 Combining caspase and mitochondrial dysfunction inhibitors of apoptosis to limit cell death in mammalian cell cultures. Biotechnol Bioeng 2006 0.91
40 Enhanced cell culture performance using inducible anti-apoptotic genes E1B-19K and Aven in the production of a monoclonal antibody with Chinese hamster ovary cells. Biotechnol Bioeng 2007 0.89
41 A comparison of the properties of a Bcl-xL variant to the wild-type anti-apoptosis inhibitor in mammalian cell cultures. Metab Eng 2003 0.86
42 Viral modulators of cell death provide new links to old pathways. Curr Opin Cell Biol 2003 0.85
43 Unravelling the bcl-2 apoptosis code with a simple model system. PLoS Biol 2008 0.82
44 Reliable method for detection of programmed cell death in yeast. Methods Mol Biol 2009 0.80
45 Quantification of genetically controlled cell death in budding yeast. Methods Mol Biol 2013 0.79
46 A quorum on bacterial programmed cell death. Mol Cell 2007 0.78
47 A Bcl-xL timer sets platelet life span. Cell 2007 0.78
48 Flying to a halt: Drosophila Aven arrests the cell cycle. Cell Cycle 2011 0.76
49 The N-terminal helix of Bcl-xL targets mitochondria. Mitochondrion 2013 0.76
50 The apoptosome at high resolution. Cell 2010 0.76
51 Regulation of cell death in the lymphoid system by Bcl-2 family proteins. Acta Haematol 2004 0.76
52 Bcl-2 turns deadly. Nat Chem Biol 2008 0.75
53 Unlatched BAX pairs for death. Cell 2013 0.75
54 Neuronal apoptosis pathways in Sindbis virus encephalitis. Prog Mol Subcell Biol 2004 0.75