PubRank

Kevin Lynch

Author PubWeight™ 46.20‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Detection of BCR-ABL mutations in patients with CML treated with imatinib is virtually always accompanied by clinical resistance, and mutations in the ATP phosphate-binding loop (P-loop) are associated with a poor prognosis. Blood 2003 3.61
2 Desirable performance characteristics for BCR-ABL measurement on an international reporting scale to allow consistent interpretation of individual patient response and comparison of response rates between clinical trials. Blood 2008 2.80
3 A-317491, a novel potent and selective non-nucleotide antagonist of P2X3 and P2X2/3 receptors, reduces chronic inflammatory and neuropathic pain in the rat. Proc Natl Acad Sci U S A 2002 2.24
4 Barriers and facilitators to primary care or human immunodeficiency virus clinics providing methadone or buprenorphine for the management of opioid dependence. Arch Intern Med 2005 1.86
5 Most CML patients who have a suboptimal response to imatinib have low OCT-1 activity: higher doses of imatinib may overcome the negative impact of low OCT-1 activity. Blood 2007 1.70
6 Impact of early dose intensity on cytogenetic and molecular responses in chronic- phase CML patients receiving 600 mg/day of imatinib as initial therapy. Blood 2008 1.64
7 Real-time quantitative PCR analysis can be used as a primary screen to identify patients with CML treated with imatinib who have BCR-ABL kinase domain mutations. Blood 2004 1.57
8 BCR-ABL messenger RNA levels continue to decline in patients with chronic phase chronic myeloid leukemia treated with imatinib for more than 5 years and approximately half of all first-line treated patients have stable undetectable BCR-ABL using strict sensitivity criteria. Clin Cancer Res 2007 1.50
9 Long-term imatinib therapy promotes bone formation in CML patients. Blood 2007 1.30
10 Analgesic profile of intrathecal P2X(3) antisense oligonucleotide treatment in chronic inflammatory and neuropathic pain states in rats. Pain 2002 1.27
11 Carotid artery dissection as a possible severe complication of pertussis in an adult: clinical case report and review. Clin Infect Dis 2002 1.26
12 Lysophosphatidic acid receptors 1 and 2 play roles in regulation of vascular injury responses but not blood pressure. Circ Res 2008 1.20
13 Off-label recombinant factor VIIa use and thrombosis in children: a multi-center cohort study. J Pediatr 2010 1.15
14 Measurement of in vivo BCR-ABL kinase inhibition to monitor imatinib-induced target blockade and predict response in chronic myeloid leukemia. J Clin Oncol 2007 1.10
15 Motivational interviewing: a pilot test of active ingredients and mechanisms of change. Psychol Addict Behav 2012 1.08
16 The nitrogen-containing bisphosphonate, zoledronic acid, increases mineralisation of human bone-derived cells in vitro. Bone 2004 1.06
17 Characterization of interleukin-4-stimulated nasal polyp fibroblasts. Am J Respir Cell Mol Biol 2003 1.03
18 Atomoxetine for treatment of marijuana dependence: a report on the efficacy and high incidence of gastrointestinal adverse events in a pilot study. Drug Alcohol Depend 2008 1.00
19 Comparing smoking treatment programs for lighter smokers with and without a history of heavier smoking. J Subst Abuse Treat 2009 0.99
20 UNIVERSAL VERSUS ECONOMICALLY POLARIZED CHANGE IN AGE AT FIRST BIRTH: A FRENCH-BRITISH COMPARISON. Popul Dev Rev 2009 0.97
21 The nitrogen-containing bisphosphonate, zoledronic acid, influences RANKL expression in human osteoblast-like cells by activating TNF-alpha converting enzyme (TACE). J Bone Miner Res 2004 0.96
22 Sensitive detection of KIT D816V in patients with mastocytosis. Clin Chem 2006 0.95
23 One-year outcomes from the CASAWORKS for Families intervention for substance-abusing women on welfare. Eval Rev 2003 0.94
24 Effectiveness of vocational problem-solving skills on motivation and job-seeking action steps. Subst Use Misuse 2004 0.92
25 Why do those who request smoking treatment fail to attend the first appointment? J Subst Abuse Treat 2007 0.91
26 Comparison of embedded and isolated administrations of the California Psychological Inventory's Socialization subscale. Psychol Assess 2003 0.90
27 Multi-centre Phase II trial of the polyamine synthesis inhibitor SAM486A (CGP48664) in patients with metastatic melanoma. Invest New Drugs 2005 0.89
28 Renal safety of zoledronic acid with thalidomide in patients with myeloma: a pharmacokinetic and safety sub-study. BMC Clin Pharmacol 2008 0.89
29 Transitions to supported environments in England and Wales among elderly widowed and divorced women: the changing balance between co-residence with family and institutional care. J Women Aging 2003 0.87
30 Online illegal drug use information: an exploratory analysis of drug-related website viewing by adolescents. J Health Commun 2009 0.86
31 MRI comparison of periprosthetic structures around zirconium knee prostheses and cobalt chrome prostheses. AJR Am J Roentgenol 2006 0.86
32 Work, permanent sickness and mortality risk: a prospective cohort study of England and Wales, 1971-2006. J Epidemiol Community Health 2010 0.85
33 Selective serotonin reuptake inhibitor suppression of HIV infectivity and replication. Psychosom Med 2010 0.84
34 Impact of tissue-specific stem cells on lineage-specific differentiation: a focus on the musculoskeletal system. Stem Cell Rev 2015 0.83
35 Asian/Pacific Islander American women: age and death rates during hospitalization for breast cancer. Oncol Nurs Forum 2004 0.82
36 Efficacy and safety of imatinib in patients with chronic myeloid leukemia and complete or near-complete cytogenetic response to interferon-alpha. Cancer 2007 0.81
37 Impact of androgen suppression and zoledronic acid on bone mineral density and fractures in the Trans-Tasman Radiation Oncology Group (TROG) 03.04 Randomised Androgen Deprivation and Radiotherapy (RADAR) randomized controlled trial for locally advanced prostate cancer. BJU Int 2014 0.80
38 Treatment of tardive dyskinesia with galantamine: a randomized controlled crossover trial. J Clin Psychiatry 2007 0.79
39 Grade 2C signal in the meniscus [correction of mensicus] on MR imaging of the knee. AJR Am J Roentgenol 2002 0.78
40 Pre-operative Identification and Surgical Management of the Appendiceal Mucocele: A Case Report. W V Med J 2016 0.75
41 Pediatric Secondary Overtriage in a Statewide Trauma System. Am Surg 2016 0.75
42 An imatinib-only window followed by imatinib and chemotherapy for Philadelphia chromosome-positive acute leukemia: long-term results of the CMLALL1 trial. Leuk Lymphoma 2014 0.75
43 Mesenchymal stem cell therapy to promote corneal allograft survival: current status and pathway to clinical translation. Curr Opin Organ Transplant 2016 0.75
44 An analysis of patient register data in the Longitudinal Study - what does it tell us about the quality of the data? Popul Trends 2010 0.75