Published in Arthritis Rheum on April 01, 2007
Mesenchymal Stem Cell Therapy for Liver Cirrhosis | NCT03626090
Mesenchymal-stem-cell-induced immunoregulation involves FAS-ligand-/FAS-mediated T cell apoptosis. Cell Stem Cell (2012) 2.87
Cell contact, prostaglandin E(2) and transforming growth factor beta 1 play non-redundant roles in human mesenchymal stem cell induction of CD4+CD25(High) forkhead box P3+ regulatory T cells. Clin Exp Immunol (2009) 2.60
Immunosuppression by mesenchymal stem cells: mechanisms and clinical applications. Stem Cell Res Ther (2010) 2.29
Immunomodulation by mesenchymal stem cells: a potential therapeutic strategy for type 1 diabetes. Diabetes (2008) 2.25
A protocol for isolation and culture of mesenchymal stem cells from mouse compact bone. Nat Protoc (2010) 2.20
Immunomodulatory function of bone marrow-derived mesenchymal stem cells in experimental autoimmune type 1 diabetes. J Immunol (2009) 2.15
Stem cell paracrine actions and tissue regeneration. Regen Med (2010) 1.99
Discrepancy between the in vitro and in vivo effects of murine mesenchymal stem cells on T-cell proliferation and collagen-induced arthritis. Arthritis Res Ther (2010) 1.95
How mesenchymal stem cells interact with tissue immune responses. Trends Immunol (2012) 1.92
IL-6-dependent PGE2 secretion by mesenchymal stem cells inhibits local inflammation in experimental arthritis. PLoS One (2010) 1.92
Therapeutic potential of human umbilical cord mesenchymal stem cells in the treatment of rheumatoid arthritis. Arthritis Res Ther (2010) 1.90
Mesenchymal stem cells: innovative therapeutic tools for rheumatic diseases. Nat Rev Rheumatol (2009) 1.88
Mesenchymal stem cells: the fibroblasts' new clothes? Haematologica (2008) 1.87
Mesenchymal stem cells prevent the rejection of fully allogenic islet grafts by the immunosuppressive activity of matrix metalloproteinase-2 and -9. Diabetes (2009) 1.78
Mesenchymal stem cells in arthritic diseases. Arthritis Res Ther (2008) 1.75
Mesenchymal stem cells impair in vivo T-cell priming by dendritic cells. Proc Natl Acad Sci U S A (2011) 1.58
MSC Transplantation Improves Osteopenia via Epigenetic Regulation of Notch Signaling in Lupus. Cell Metab (2015) 1.49
Journey of mesenchymal stem cells for homing: strategies to enhance efficacy and safety of stem cell therapy. Stem Cells Int (2012) 1.41
Mesenchymal stem cells overexpressing interleukin-10 attenuate collagen-induced arthritis in mice. Clin Exp Immunol (2008) 1.32
MSCs: Delivery Routes and Engraftment, Cell-Targeting Strategies, and Immune Modulation. Stem Cells Int (2013) 1.30
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Immunogenicity of human mesenchymal stem cells in HLA-class I-restricted T-cell responses against viral or tumor-associated antigens. Stem Cells (2008) 1.28
Mesenchymal stem cell-based therapies in regenerative medicine: applications in rheumatology. Stem Cell Res Ther (2011) 1.28
Allogeneic endometrial regenerative cells: an "Off the shelf solution" for critical limb ischemia? J Transl Med (2008) 1.27
Immunomodulatory properties of human adult and fetal multipotent mesenchymal stem cells. J Biomed Sci (2011) 1.20
Immunological applications of stem cells in type 1 diabetes. Endocr Rev (2011) 1.20
Mesenchymal stem cells as therapeutics and vehicles for gene and drug delivery. Adv Drug Deliv Rev (2010) 1.18
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Feasibility investigation of allogeneic endometrial regenerative cells. J Transl Med (2009) 1.10
Flk-1+ mesenchymal stem cells aggravate collagen-induced arthritis by up-regulating interleukin-6. Clin Exp Immunol (2009) 1.09
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Interplay between mesenchymal stem cells and lymphocytes: implications for immunotherapy and tissue regeneration. J Dent Res (2012) 1.05
Mesenchymal stem cells, autoimmunity and rheumatoid arthritis. QJM (2014) 1.04
Human mesenchymal stem cells - current trends and future prospective. Biosci Rep (2015) 1.04
Mesenchymal stem cells induce functionally active T-regulatory lymphocytes in a paracrine fashion and ameliorate experimental autoimmune uveitis. Invest Ophthalmol Vis Sci (2012) 1.02
Mesenchymal stem cells as a potent cell source for articular cartilage regeneration. World J Stem Cells (2014) 1.01
Allogeneic mesenchymal stem cells do not protect NZBxNZW F1 mice from developing lupus disease. Clin Exp Immunol (2010) 1.00
The potential use of mesenchymal stem cells in hematopoietic stem cell transplantation. Exp Mol Med (2013) 1.00
Stem cell treatment for patients with autoimmune disease by systemic infusion of culture-expanded autologous adipose tissue derived mesenchymal stem cells. J Transl Med (2011) 0.99
Clinical applications of mesenchymal stem cells in chronic diseases. Stem Cells Int (2014) 0.98
Alterations in the self-renewal and differentiation ability of bone marrow mesenchymal stem cells in a mouse model of rheumatoid arthritis. Arthritis Res Ther (2010) 0.98
The therapeutic effect of mesenchymal stem cell transplantation in experimental autoimmune encephalomyelitis is mediated by peripheral and central mechanisms. Stem Cell Res Ther (2012) 0.97
The therapeutic efficacy of human adipose tissue-derived mesenchymal stem cells on experimental autoimmune hearing loss in mice. Immunology (2011) 0.96
Mesenchymal Stem Cells: Rising Concerns over Their Application in Treatment of Type One Diabetes Mellitus. J Diabetes Res (2015) 0.95
Bone marrow stromal cell transplants prevent experimental enterocolitis and require host CD11b+ splenocytes. Gastroenterology (2010) 0.94
Tissue engineering in the rheumatic diseases. Arthritis Res Ther (2009) 0.94
Immunogenicity of allogeneic adipose-derived stem cells in a rat spinal fusion model. Tissue Eng Part A (2009) 0.93
Mesenchymal stem cells express serine protease inhibitor to evade the host immune response. Blood (2010) 0.93
Update on mesenchymal stem cell-based therapy in lupus and scleroderma. Arthritis Res Ther (2015) 0.93
Therapeutic application of mesenchymal stem cells in bone and joint diseases. Clin Exp Med (2012) 0.93
Genetic mismatch affects the immunosuppressive properties of mesenchymal stem cells in vitro and their ability to influence the course of collagen-induced arthritis. Arthritis Res Ther (2012) 0.92
Fibroblast growth factor-1 is a mesenchymal stromal cell-secreted factor stimulating proliferation of osteoarthritic chondrocytes in co-culture. Stem Cells Dev (2013) 0.91
Mesenchymal stem/stromal cells as a delivery platform in cell and gene therapies. BMC Med (2015) 0.91
Adipose-derived stem cells ameliorate allergic airway inflammation by inducing regulatory T cells in a mouse model of asthma. Mediators Inflamm (2014) 0.90
Mesenchymal stem cell-based treatment for microvascular and secondary complications of diabetes mellitus. Front Endocrinol (Lausanne) (2014) 0.90
Autophagy regulates the therapeutic potential of mesenchymal stem cells in experimental autoimmune encephalomyelitis. Autophagy (2014) 0.90
New strategies for overcoming limitations of mesenchymal stem cell-based immune modulation. Int J Stem Cells (2015) 0.90
Cell-based approaches to joint surface repair: a research perspective. Osteoarthritis Cartilage (2013) 0.89
Mesenchymal stem-cell immunosuppressive capabilities: therapeutic implications in islet transplantation. Transplantation (2010) 0.89
Mesenchymal stem cells immunosuppressive properties: is it specific to bone marrow-derived cells? Stem Cell Res Ther (2010) 0.89
Mesenchymal stem cells in the treatment of inflammatory and autoimmune diseases in experimental animal models. World J Stem Cells (2015) 0.89
Toward personalized cell therapies by using stem cells: seven relevant topics for safety and success in stem cell therapy. J Biomed Biotechnol (2012) 0.89
Osteoarthritis prevention through meniscal regeneration induced by intra-articular injection of meniscus stem cells. Stem Cells Dev (2013) 0.88
Growth differentiation factor-5 enhances in vitro mesenchymal stromal cell chondrogenesis and hypertrophy. Stem Cells Dev (2013) 0.88
Intra-articular injection of mesenchymal stem cells leads to reduced inflammation and cartilage damage in murine antigen-induced arthritis. J Transl Med (2014) 0.87
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Human mesenchymal stromal cell-mediated immunoregulation: mechanisms of action and clinical applications. Bone Marrow Res (2013) 0.85
Combination stem cell therapy for heart failure. Int Arch Med (2010) 0.85
Chondrogenic differentiation increases antidonor immune response to allogeneic mesenchymal stem cell transplantation. Mol Ther (2013) 0.85
Aire controls mesenchymal stem cell-mediated suppression in chronic colitis. Mol Ther (2011) 0.85
Adipose-Derived Stem Cells Ameliorate Experimental Murine Colitis via TSP-1-Dependent Activation of Latent TGF-β. Dig Dis Sci (2017) 0.85
Reconciling the effects of inflammatory cytokines on mesenchymal cell osteogenic differentiation. J Surg Res (2013) 0.84
Are mesenchymal stromal cells immune cells? Arthritis Res Ther (2015) 0.83
The influence of bone marrow- and synovium-derived mesenchymal stromal cells from osteoarthritis patients on regulatory T cells in co-culture. Clin Exp Immunol (2013) 0.83
Identification of miR-27b as a novel signature from the mRNA profiles of adipose-derived mesenchymal stem cells involved in the tolerogenic response. PLoS One (2013) 0.83
Dissection of the osteogenic effects of laminin-332 utilizing specific LG domains: LG3 induces osteogenic differentiation, but not mineralization. Exp Cell Res (2008) 0.83
PI3kα and STAT1 Interplay Regulates Human Mesenchymal Stem Cell Immune Polarization. Stem Cells (2015) 0.82
Preclinical efficacy and mechanisms of mesenchymal stem cells in animal models of autoimmune diseases. Immune Netw (2014) 0.82
Allogeneic murine mesenchymal stem cells: migration to inflamed joints in vivo and amelioration of collagen induced arthritis when transduced to express CTLA4Ig. Stem Cells Dev (2013) 0.82
Advancements in immune tolerance. Adv Drug Deliv Rev (2007) 0.82
Human Bone Marrow Derived Mesenchymal Stem Cells Regulate Leukocyte-Endothelial Interactions and Activation of Transcription Factor NF-Kappa B. J Tissue Sci Eng (2011) 0.82
Autologous stromal vascular fraction therapy for rheumatoid arthritis: rationale and clinical safety. Int Arch Med (2012) 0.82
The co-transplantation of bone marrow derived mesenchymal stem cells reduced inflammation in intramuscular islet transplantation. PLoS One (2015) 0.81
Unexpected roles for bone marrow stromal cells (or MSCs): a real promise for cellular, but not replacement, therapy. Oral Dis (2009) 0.81
Mesenchymal stem cells for the treatment of systemic lupus erythematosus: is the cure for connective tissue diseases within connective tissue? Stem Cell Res Ther (2011) 0.81
SOCS1 regulates the immune modulatory properties of mesenchymal stem cells by inhibiting nitric oxide production. PLoS One (2014) 0.81
Comparison of drug and cell-based delivery: engineered adult mesenchymal stem cells expressing soluble tumor necrosis factor receptor II prevent arthritis in mouse and rat animal models. Stem Cells Transl Med (2013) 0.81
Mesenchymal stem cells in arthritis: role of bone marrow microenvironment. Arthritis Res Ther (2010) 0.81
Stem cell therapeutics: potential in the treatment of inflammatory bowel disease. Clin Exp Gastroenterol (2010) 0.81
Therapeutic effects of mouse bone marrow-derived clonal mesenchymal stem cells in a mouse model of inflammatory bowel disease. J Clin Biochem Nutr (2015) 0.81
Concise review: immunological properties of ocular surface and importance of limbal stem cells for transplantation. Stem Cells Transl Med (2013) 0.80
Multipotent Mesenchymal Stromal Cells for Autoimmune Diseases. Transfus Med Hemother (2008) 0.80
Harnessing the immunomodulatory and tissue repair properties of mesenchymal stem cells to restore β cell function. Curr Diab Rep (2012) 0.80
Acquiring chondrocyte phenotype from human mesenchymal stem cells under inflammatory conditions. Int J Mol Sci (2014) 0.80
CDH2 and CDH11 act as regulators of stem cell fate decisions. Stem Cell Res (2015) 0.80
Adipose-Derived Mesenchymal Stem Cells Prevent Systemic Bone Loss in Collagen-Induced Arthritis. J Immunol (2015) 0.80
Metabolomic study of collagen-induced arthritis in rats and the interventional effects of huang-lian-jie-du-tang, a traditional chinese medicine. Evid Based Complement Alternat Med (2013) 0.80
Interleukin-17A- or tumor necrosis factor α-mediated increase in proliferation of T cells cocultured with synovium-derived mesenchymal stem cells in rheumatoid arthritis. Arthritis Res Ther (2013) 0.80
Human embryonic stem cell-derived mesenchymal stromal cells ameliorate collagen-induced arthritis by inducing host-derived indoleamine 2,3 dioxygenase. Arthritis Res Ther (2016) 0.79
Cardiotoxicity of anticancer drugs: the need for cardio-oncology and cardio-oncological prevention. J Natl Cancer Inst (2009) 2.55
Bone marrow mesenchymal progenitor cells inhibit lymphocyte proliferation by activation of the programmed death 1 pathway. Eur J Immunol (2005) 2.34
Stem cells associated with macroporous bioceramics for long bone repair: 6- to 7-year outcome of a pilot clinical study. Tissue Eng (2007) 2.10
Ex vivo enrichment of mesenchymal cell progenitors by fibroblast growth factor 2. Exp Cell Res (2003) 1.78
Role of scaffold internal structure on in vivo bone formation in macroporous calcium phosphate bioceramics. Biomaterials (2006) 1.55
Bone marrow stromal cells (BMSCs) in bone engineering: limitations and recent advances. Ann Biomed Eng (2004) 1.54
Immunomodulatory properties of mesenchymal stem cells: a review based on an interdisciplinary meeting held at the Kennedy Institute of Rheumatology Division, London, UK, 31 October 2005. Arthritis Res Ther (2007) 1.35
Comparative evaluation of autologous chondrocyte implantation and mosaicplasty: a multicentered randomized clinical trial. Clin J Sport Med (2005) 1.20
Replicative aging and gene expression in long-term cultures of human bone marrow stromal cells. Tissue Eng (2002) 1.19
Development of sarcomas in mice implanted with mesenchymal stem cells seeded onto bioscaffolds. Carcinogenesis (2008) 1.15
The tumor microenvironment of colorectal cancer: stromal TLR-4 expression as a potential prognostic marker. J Transl Med (2010) 1.14
The development of tissue-engineered bone of different origin through endochondral and intramembranous ossification following the implantation of mesenchymal stem cells and osteoblasts in a murine model. Biomaterials (2009) 1.14
New small nuclear RNA gene-like transcriptional units as sources of regulatory transcripts. PLoS Genet (2006) 1.14
The recruitment of two consecutive and different waves of host stem/progenitor cells during the development of tissue-engineered bone in a murine model. Biomaterials (2009) 1.12
Targeted expression of SHH affects chondrocyte differentiation, growth plate organization, and Sox9 expression. J Bone Miner Res (2004) 1.10
Recruitment of a host's osteoprogenitor cells using exogenous mesenchymal stem cells seeded on porous ceramic. Tissue Eng Part A (2009) 1.09
An Alu-like RNA promotes cell differentiation and reduces malignancy of human neuroblastoma cells. FASEB J (2010) 1.08
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A cell-free scaffold-based cartilage repair provides improved function hyaline-like repair at one year. Clin Orthop Relat Res (2011) 1.06
Response of young, aged and osteoarthritic human articular chondrocytes to inflammatory cytokines: molecular and cellular aspects. Matrix Biol (2002) 1.06
Cartilage and bone extracellular matrix. Curr Pharm Des (2009) 1.06
Selection of candidate housekeeping genes for normalization in human postmortem brain samples. Int J Mol Sci (2011) 1.05
p38/NF-kB-dependent expression of COX-2 during differentiation and inflammatory response of chondrocytes. J Cell Biochem (2008) 1.04
Reconstruction of extensive long bone defects in sheep using resorbable bioceramics based on silicon stabilized tricalcium phosphate. Tissue Eng (2006) 1.03
NDM29, a RNA polymerase III-dependent non coding RNA, promotes amyloidogenic processing of APP and amyloid β secretion. Biochim Biophys Acta (2012) 1.02
Mesenchymal stem cells induce functionally active T-regulatory lymphocytes in a paracrine fashion and ameliorate experimental autoimmune uveitis. Invest Ophthalmol Vis Sci (2012) 1.02
Formation of a chondro-osseous rudiment in micromass cultures of human bone-marrow stromal cells. J Cell Sci (2003) 1.02
RNA polymerase III drives alternative splicing of the potassium channel-interacting protein contributing to brain complexity and neurodegeneration. J Cell Biol (2011) 1.01
Depletion of cartilage collagen fibrils in mice carrying a dominant negative Col2a1 transgene affects chondrocyte differentiation. Am J Physiol Cell Physiol (2003) 0.99
Dichloroacetate inhibits neuroblastoma growth by specifically acting against malignant undifferentiated cells. Int J Cancer (2011) 0.99
Amniotic liquid derived stem cells as reservoir of secreted angiogenic factors capable of stimulating neo-arteriogenesis in an ischemic model. Biomaterials (2011) 0.98
Mouse models of experimental autoimmune uveitis. Ophthalmic Res (2008) 0.97
Bone turnover in wild type and pleiotrophin-transgenic mice housed for three months in the International Space Station (ISS). PLoS One (2012) 0.97
Carrageenan-based hydrogels for the controlled delivery of PDGF-BB in bone tissue engineering applications. Biomacromolecules (2009) 0.95
Acquisition of neuron-like electrophysiological properties in neuroblastoma cells by controlled expression of NDM29 ncRNA. J Neurochem (2011) 0.95
Dual effect of platelet lysate on human articular cartilage: a maintenance of chondrogenic potential and a transient proinflammatory activity followed by an inflammation resolution. Tissue Eng Part A (2013) 0.93
The role of bFGF on the ability of MSC to activate endogenous regenerative mechanisms in an ectopic bone formation model. Biomaterials (2011) 0.93
Galline Ex-FABP is an antibacterial siderocalin and a lysophosphatidic acid sensor functioning through dual ligand specificities. Structure (2011) 0.91
An intronic ncRNA-dependent regulation of SORL1 expression affecting Aβ formation is upregulated in post-mortem Alzheimer's disease brain samples. Dis Model Mech (2012) 0.91
Integrins alpha(6A)beta 1 and alpha(6B)beta 1 promote different stages of chondrogenic cell differentiation. J Biol Chem (2002) 0.90
Fluorescence microscopy imaging of bone for automated histomorphometry. Tissue Eng (2002) 0.89
A platelet-rich plasma-based membrane as a periosteal substitute with enhanced osteogenic and angiogenic properties: a new concept for bone repair. Tissue Eng Part A (2012) 0.88
Effects of long-term space flight on erythrocytes and oxidative stress of rodents. PLoS One (2012) 0.88
Activation of nervous system development genes in bone marrow derived mesenchymal stem cells following spaceflight exposure. J Cell Biochem (2010) 0.87
Cartilage repair in the knee with subchondral drilling augmented with a platelet-rich plasma-immersed polymer-based implant. Knee Surg Sports Traumatol Arthrosc (2013) 0.87
Three dimensional visualization of engineered bone and soft tissue by combined x-ray micro-diffraction and phase contrast tomography. Phys Med Biol (2013) 0.87
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In vivo implanted bone marrow-derived mesenchymal stem cells trigger a cascade of cellular events leading to the formation of an ectopic bone regenerative niche. Stem Cells Dev (2013) 0.85
Serum-free growth medium sustains commitment of human articular chondrocyte through maintenance of Sox9 expression. Tissue Eng (2004) 0.85
When stem cells meet immunoregulation. Int Immunopharmacol (2009) 0.85
Expression of serum amyloid A in chondrocytes and myoblasts differentiation and inflammation: possible role in cholesterol homeostasis. Matrix Biol (2004) 0.85
Proangiogenic soluble factors from amniotic fluid stem cells mediate the recruitment of endothelial progenitors in a model of ischemic fasciocutaneous flap. Stem Cells Dev (2012) 0.85
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A novel snRNA-like transcript affects amyloidogenesis and cell cycle progression through perturbation of Fe65L1 (APBB2) alternative splicing. Biochim Biophys Acta (2013) 0.85
Organization of extracellular matrix fibers within polyglycolic acid-polylactic acid scaffolds analyzed using X-ray synchrotron-radiation phase-contrast micro computed tomography. Tissue Eng Part C Methods (2009) 0.85
CALbeta, a novel lipocalin associated with chondrogenesis and inflammation. Eur J Cell Biol (2002) 0.85
Ex-FABP, extracellular fatty acid binding protein, is a stress lipocalin expressed during chicken embryo development. Mol Cell Biochem (2002) 0.84
Platelet-rich plasma exerts antinociceptive activity by a peripheral endocannabinoid-related mechanism. Tissue Eng Part A (2013) 0.84
Differentially expressed genes in MHC-compatible rat strains that are susceptible or resistant to experimental autoimmune uveitis. Invest Ophthalmol Vis Sci (2008) 0.84
Impaired expression of genes coding for reactive oxygen species scavenging enzymes in testes of Mtfr1/Chppr-deficient mice. Reproduction (2007) 0.84
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A simple non invasive computerized method for the assessment of bone repair within osteoconductive porous bioceramic grafts. Biotechnol Bioeng (2005) 0.84
Anti-inflammatory activity of monogalactosyldiacylglycerol in human articular cartilage in vitro: activation of an anti-inflammatory cyclooxygenase-2 (COX-2) pathway. Arthritis Res Ther (2011) 0.84
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Gene expression profile of human bone marrow stromal cells determined by restriction fragment differential display analysis. J Cell Biochem (2004) 0.83
DLX5 overexpression impairs osteogenic differentiation of human bone marrow stromal cells. Eur J Cell Biol (2008) 0.83
Chondrocyte protein with a poly-proline region (CHPPR) is a novel mitochondrial protein and promotes mitochondrial fission. J Cell Physiol (2004) 0.83
Mesenchymal stem cell paracrine activity is modulated by platelet lysate: induction of an inflammatory response and secretion of factors maintaining macrophages in a proinflammatory phenotype. Stem Cells Dev (2014) 0.83
A common pathway in differentiation and inflammation: p38 mediates expression of the acute phase SIP24 iron binding lipocalin in chondrocytes. J Cell Physiol (2006) 0.83
A novel collection of snRNA-like promoters with tissue-specific transcription properties. Int J Mol Sci (2012) 0.83
The nuclear genes Mtfr1 and Dufd1 regulate mitochondrial dynamic and cellular respiration. J Cell Physiol (2010) 0.82
Evaluation of gene, protein and neurotrophin expression in the brain of mice exposed to space environment for 91 days. PLoS One (2012) 0.82
Phylogeny and regulation of four lipocalin genes clustered in the chicken genome: evidence of a functional diversification after gene duplication. Gene (2004) 0.82
Stem cell plasticity: time for a reappraisal? Haematologica (2005) 0.82
Recruitment of host's progenitor cells to sites of human amniotic fluid stem cells implantation. Biomaterials (2011) 0.82
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15-deoxy-delta 12,14-prostaglandin J(2) inhibits the synthesis of the acute phase protein SIP24 in cartilage: Involvement of COX-2 in resolution of inflammation. J Cell Physiol (2008) 0.80
Platelet lysate induces in vitro wound healing of human keratinocytes associated with a strong proinflammatory response. Tissue Eng Part A (2011) 0.80
The Murine PSE/TATA-dependent transcriptome: evidence of functional homologies with its human counterpart. Int J Mol Sci (2012) 0.80
X-ray synchrotron radiation pseudo-holotomography as a new imaging technique to investigate angio- and microvasculogenesis with no usage of contrast agents. Tissue Eng Part C Methods (2009) 0.80
The effect of Platelet Lysate on osteoblast proliferation associated with a transient increase of the inflammatory response in bone regeneration. Biomaterials (2013) 0.79
Graft materials and bone marrow stromal cells in bone tissue engineering. J Biomater Appl (2011) 0.79
Lipocalin-2 controls the expression of SDF-1 and the number of responsive cells in bone. Cytokine (2010) 0.79