Published in Bioorg Med Chem Lett on March 15, 2007
Recombinant human interleukin-1 receptor antagonist in severe traumatic brain injury: a phase II randomized control trial. J Cereb Blood Flow Metab (2014) 0.97
CCR4 contributes to the pathogenesis of experimental autoimmune encephalomyelitis by regulating inflammatory macrophage function. J Neuroimmunol (2011) 0.89
Detrimental role of CC chemokine receptor 4 in murine polymicrobial sepsis. Infect Immun (2008) 0.89
Distinct conformations of the chemokine receptor CCR4 with implications for its targeting in allergy. J Immunol (2014) 0.83
Ccl22/MDC, is a prostaglandin dependent pyrogen, acting in the anterior hypothalamus to induce hyperthermia via activation of brown adipose tissue. Cytokine (2010) 0.81
Molecular requirements for inhibition of the chemokine receptor CCR8--probe-dependent allosteric interactions. Br J Pharmacol (2012) 0.81
Targeting chemokine receptors in disease - a case study of CCR4. Eur J Pharmacol (2015) 0.75
Room temperature synthesis and antibacterial activity of new sulfonamides containing n,n-diethyl-substituted amido moieties. Int J Med Chem (2012) 0.75
Discovery of AZD-2098 and AZD-1678, Two Potent and Bioavailable CCR4 Receptor Antagonists. ACS Med Chem Lett (2017) 0.75
Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonella-infected macrophages. Nat Immunol (2006) 10.55
Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3. Nature (2006) 9.77
Obesity and cancer. Oncologist (2010) 3.01
Role of breast regression protein 39 (BRP-39)/chitinase 3-like-1 in Th2 and IL-13-induced tissue responses and apoptosis. J Exp Med (2009) 2.61
A critical role for peptidoglycan N-deacetylation in Listeria evasion from the host innate immune system. Proc Natl Acad Sci U S A (2007) 2.46
Distinct roles of TLR2 and the adaptor ASC in IL-1beta/IL-18 secretion in response to Listeria monocytogenes. J Immunol (2006) 2.21
The identification and characterization of breast cancer CTCs competent for brain metastasis. Sci Transl Med (2013) 2.18
Role of the CXCR4/SDF-1 chemokine axis in circulating neutrophil homeostasis. Blood (2004) 2.17
A critical role for the programmed death ligand 1 in fetomaternal tolerance. J Exp Med (2005) 2.13
Type I interferon: potential therapeutic target for psoriasis? PLoS One (2008) 2.08
Fibromyalgia syndrome. J Rheumatol (2007) 2.04
Chirality transfer from guest chiral metal complexes to inorganic framework: the role of hydrogen bonding. Chemistry (2003) 1.73
Erythropoietin promotes neuronal replacement through revascularization and neurogenesis after neonatal hypoxia/ischemia in rats. Stroke (2007) 1.59
Neuroprotection against focal ischemic brain injury by inhibition of c-Jun N-terminal kinase and attenuation of the mitochondrial apoptosis-signaling pathway. J Cereb Blood Flow Metab (2005) 1.55
Rapid TNFR1-dependent lymphocyte depletion in vivo with a selective chemical inhibitor of IKKbeta. Blood (2006) 1.51
Impaired growth hormone secretion in fibromyalgia patients: evidence for augmented hypothalamic somatostatin tone. Arthritis Rheum (2002) 1.51
Neuroprotection against focal ischemic brain injury by the peroxisome proliferator-activated receptor-gamma agonist rosiglitazone. J Neurochem (2006) 1.50
Translocation of apoptosis-inducing factor in vulnerable neurons after transient cerebral ischemia and in neuronal cultures after oxygen-glucose deprivation. J Cereb Blood Flow Metab (2003) 1.46
Early warning of cotton bollworm resistance associated with intensive planting of Bt cotton in China. PLoS One (2011) 1.46
A selective small molecule IkappaB Kinase beta inhibitor blocks nuclear factor kappaB-mediated inflammatory responses in human fibroblast-like synoviocytes, chondrocytes, and mast cells. J Pharmacol Exp Ther (2006) 1.36
Raman spectroscopy, a potential tool for the objective identification and classification of neoplasia in Barrett's oesophagus. J Pathol (2003) 1.31
Characterization of the H5N1 highly pathogenic avian influenza virus derived from wild pikas in China. J Virol (2009) 1.27
Tunable spin loading and T1 of a silicon spin qubit measured by single-shot readout. Phys Rev Lett (2011) 1.27
Flow-induced platelet activation in mechanical heart valves. J Heart Valve Dis (2004) 1.25
Complement activation on platelets: implications for vascular inflammation and thrombosis. Mol Immunol (2010) 1.24
Induction of microRNA-1 by myocardin in smooth muscle cells inhibits cell proliferation. Arterioscler Thromb Vasc Biol (2010) 1.21
Highly stable chiral cadmium 1,2,4-benzenetricarboxylate: synthesis, structure, and NLO and fluorescence properties. Inorg Chem (2006) 1.20
ORFDB: an information resource linking scientific content to a high-quality Open Reading Frame (ORF) collection. Nucleic Acids Res (2004) 1.19
Fragile X syndrome: an update on developing treatment modalities. ACS Chem Neurosci (2011) 1.18
IL-10-conditioned dendritic cells, decommissioned for recruitment of adaptive immunity, elicit innate inflammatory gene products in response to danger signals. J Immunol (2004) 1.18
Allocation of child medical care decision-making authority: a suggested interest analysis. Va Law Rev (1976) 1.17
An anti-inflammatory role for plasmacytoid dendritic cells in allergic airway inflammation. J Immunol (2009) 1.17
HMGB1-secreting capacity of multiple cell lineages revealed by a novel HMGB1 ELISPOT assay. J Leukoc Biol (2006) 1.16
Platelet activation in a circulating flow loop: combined effects of shear stress and exposure time. Platelets (2003) 1.15
PKC-theta-deficient mice are protected from Th1-dependent antigen-induced arthritis. J Immunol (2006) 1.13
Mice deficient in PKC theta demonstrate impaired in vivo T cell activation and protection from T cell-mediated inflammatory diseases. Autoimmunity (2006) 1.12
Cholera toxin induces malignant glioma cell differentiation via the PKA/CREB pathway. Proc Natl Acad Sci U S A (2007) 1.11
Concurrent blockade of platelet-activating factor and histamine prevents life-threatening peanut-induced anaphylactic reactions. J Allergy Clin Immunol (2009) 1.11
Hyperbaric oxygenation prevented brain injury induced by hypoxia-ischemia in a neonatal rat model. Brain Res (2002) 1.10
1H NMR spectroscopy-based interventional metabolic phenotyping: a cohort study of rheumatoid arthritis patients. J Proteome Res (2010) 1.09
Role of regulator of G protein signaling 16 in inflammation-induced T lymphocyte migration and activation. J Immunol (2003) 1.08
Delayed wound closure in fibromodulin-deficient mice is associated with increased TGF-β3 signaling. J Invest Dermatol (2010) 1.07
Compatibility of interventional x-ray and magnetic resonance imaging: feasibility of a closed bore XMR (CBXMR) system. Med Phys (2006) 1.06
Use of molecular imaging to quantify response to IKK-2 inhibitor treatment in murine arthritis. Arthritis Rheum (2007) 1.06
Regulation of IRAK-4 kinase activity via autophosphorylation within its activation loop. Biochem Biophys Res Commun (2006) 1.05
Type I interferons produced by resident renal cells may promote end-organ disease in autoantibody-mediated glomerulonephritis. J Immunol (2009) 1.04
Participation of Rip2 in lipopolysaccharide signaling is independent of its kinase activity. J Biol Chem (2005) 1.03
A systematic review and meta-analysis on the use of traditional Chinese medicine compound kushen injection for bone cancer pain. Support Care Cancer (2013) 1.01
Deleterious effects of plasminogen activators in neonatal cerebral hypoxia-ischemia. Am J Pathol (2008) 1.01
Apoptosis in cerebral ischemia: executional and regulatory signaling mechanisms. Neurol Res (2004) 1.01
Obesity, emerging risk in China: trend of increasing prevalence of obesity and its association with hypertension and hypercholesterolaemia among the Chinese. Clin Exp Pharmacol Physiol (2004) 1.01
Myomectomy during cesarean section. Acta Obstet Gynecol Scand (2009) 1.01
Assessment of bioaccessibility and exposure risk of arsenic and lead in urban soils of Guangzhou City, China. Environ Geochem Health (2010) 1.00
Distribution of heavy metals in agricultural soils near a petrochemical complex in Guangzhou, China. Environ Monit Assess (2008) 0.99
An organically templated cobalt-vanadium oxide with beta cage units: hydrothermal synthesis and x-ray structural characterization of (C(2)H(10)N(2))[Co(2)(C(2)O(4))V(4)O(12)]. Inorg Chem (2003) 0.99
Enhanced binding affinity, remarkable selectivity, and high capacity of CO2 by dual functionalization of a rht-type metal-organic framework. Angew Chem Int Ed Engl (2011) 0.98
Validation of the anti-inflammatory properties of small-molecule IkappaB Kinase (IKK)-2 inhibitors by comparison with adenoviral-mediated delivery of dominant-negative IKK1 and IKK2 in human airways smooth muscle. Mol Pharmacol (2006) 0.98
Examination of platelet function in whole blood under dynamic flow conditions with the cone and plate(let) analyzer: effect of erythrocytosis and thrombocytosis. Am J Clin Pathol (2007) 0.97
IKKbeta inhibition protects against bone and cartilage destruction in a rat model of rheumatoid arthritis. Arthritis Rheum (2006) 0.96
A solution-phase bifunctional catalyst for lithium-oxygen batteries. J Am Chem Soc (2014) 0.96
The use of BMP-2 coupled - Nanosilver-PLGA composite grafts to induce bone repair in grossly infected segmental defects. Biomaterials (2010) 0.96
Quantitative analysis of micro-CT imaging and histopathological signatures of experimental arthritis in rats. Mol Imaging (2004) 0.95
Complement activation on platelets correlates with a decrease in circulating immature platelets in patients with immune thrombocytopenic purpura. Br J Haematol (2009) 0.94
Risk factors at pretreatment predicting treatment-induced nausea and vomiting in Australian cancer patients: a prospective, longitudinal, observational study. Support Care Cancer (2010) 0.94
Hsp20, a novel alpha-crystallin, prevents Abeta fibril formation and toxicity. Protein Sci (2005) 0.93
Reprogramming of human fibroblasts into multipotent cells with a single ECM proteoglycan, fibromodulin. Biomaterials (2012) 0.92
Design and construction of coordination polymers based on 2,2'-dinitro-4,4'-biphenyldicarboxylate and semi-rigid N-donor ligands: diverse structures and magnetic properties. Dalton Trans (2012) 0.92
I kappa B kinase 2/beta deficiency controls expansion of autoreactive T cells and suppresses experimental autoimmune encephalomyelitis. J Immunol (2007) 0.92
Identification and characterization of SF2000 and SF2001, two new members of the immune receptor SLAM/CD2 family. Immunogenetics (2002) 0.92
Single-shot measurement of triplet-singlet relaxation in a Si/SiGe double quantum dot. Phys Rev Lett (2012) 0.91
Evaluation of a 6-year highly active antiretroviral therapy in Chinese HIV-1-infected patients. Intervirology (2010) 0.91
Constructing octa- and hexadecanuclear manganese clusters from tetrahedral Mn(III)(3)Mn(II) cores bridged by quinquedentate Schiff base and versatile azide groups. Dalton Trans (2010) 0.91
Pharmacologic uncoupling of angiogenesis and inflammation during initiation of pathological corneal neovascularization. J Biol Chem (2011) 0.90
Small heat shock proteins differentially affect Abeta aggregation and toxicity. Biochem Biophys Res Commun (2006) 0.90
Breakthrough in concentration quenching threshold of upconversion luminescence via spatial separation of the emitter doping area for bio-applications. Chem Commun (Camb) (2011) 0.90
Comparative cytological and transcriptomic analysis of pollen development in autotetraploid and diploid rice. Plant Reprod (2014) 0.89
Transcriptome analysis of Deinagkistrodon acutus venomous gland focusing on cellular structure and functional aspects using expressed sequence tags. BMC Genomics (2006) 0.89
Identification of 4-piperazin-1-yl-quinazoline template based aryl and benzyl thioureas as potent, selective, and orally bioavailable inhibitors of platelet-derived growth factor (PDGF) receptor. Bioorg Med Chem Lett (2004) 0.89
Glycated albumin modulates endothelial cell thrombogenic and inflammatory responses. J Diabetes Sci Technol (2011) 0.89
Platelet mediated complement activation. Adv Exp Med Biol (2008) 0.88
Caveat medicus: consequences of federal investigations of marketing activities of pharmaceutical suppliers of prostate cancer drugs. J Clin Oncol (2005) 0.87
Novel potent inhibitors of deoxycytidine kinase identified and compared by multiple assays. J Biomol Screen (2009) 0.87
Passive Smoking and Other Factors at Different Periods of Life and Breast Cancer Risk in Chinese Women who have Never Smoked - A Case-control Study in Chongqing, People's Republic of China. Asian Pac J Cancer Prev (2000) 0.87
Design, synthesis, and progress toward optimization of potent small molecule antagonists of CC chemokine receptor 8 (CCR8). J Med Chem (2006) 0.87
The genetics of Henoch-Schönlein purpura: a systematic review and meta-analysis. Rheumatol Int (2013) 0.86
Nausea still the poor relation in antiemetic therapy? The impact on cancer patients' quality of life and psychological adjustment of nausea, vomiting and appetite loss, individually and concurrently as part of a symptom cluster. Support Care Cancer (2012) 0.86
PAR2-mediated upregulation of BDNF contributes to central sensitization in bone cancer pain. Mol Pain (2014) 0.86
Efficacy of extracorporeal shockwave therapy for knee osteoarthritis: a randomized controlled trial. J Surg Res (2013) 0.86
Ultracompact polarization splitter-rotator based on an asymmetric directional coupler. Appl Opt (2012) 0.86
Selective cell adhesion inhibitors: Barbituric acid based alpha4beta7--MAdCAM inhibitors. Bioorg Med Chem Lett (2007) 0.85