PubRank

Thomas P Shanley

Author PubWeight™ 95.09‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Genome-level expression profiles in pediatric septic shock indicate a role for altered zinc homeostasis in poor outcome. Physiol Genomics 2007 3.37
2 Genomic expression profiling across the pediatric systemic inflammatory response syndrome, sepsis, and septic shock spectrum. Crit Care Med 2009 3.16
3 Identification of pediatric septic shock subclasses based on genome-wide expression profiling. BMC Med 2009 2.23
4 Validation of a gene expression-based subclassification strategy for pediatric septic shock. Crit Care Med 2011 2.20
5 Extracorporeal life support for severe respiratory failure in children with immune compromised conditions. Pediatr Crit Care Med 2008 2.17
6 Developing a clinically feasible personalized medicine approach to pediatric septic shock. Am J Respir Crit Care Med 2015 2.09
7 Leukocyte subset-derived genomewide expression profiles in pediatric septic shock. Pediatr Crit Care Med 2010 2.01
8 The pediatric sepsis biomarker risk model. Crit Care 2012 1.99
9 Fluid overload and fluid removal in pediatric patients on extracorporeal membrane oxygenation requiring continuous renal replacement therapy. Crit Care Med 2012 1.99
10 Validating the genomic signature of pediatric septic shock. Physiol Genomics 2008 1.96
11 The ideal time interval for critical care severity-of-illness assessment. Pediatr Crit Care Med 2013 1.91
12 Weight-based determination of fluid overload status and mortality in pediatric intensive care unit patients requiring continuous renal replacement therapy. Intensive Care Med 2011 1.79
13 Do outcomes vary according to the source of admission to the pediatric intensive care unit? Pediatr Crit Care Med 2008 1.74
14 Critical pertussis illness in children: a multicenter prospective cohort study. Pediatr Crit Care Med 2013 1.74
15 Post-ICU admission fluid balance and pediatric septic shock outcomes: a risk-stratified analysis. Crit Care Med 2014 1.72
16 The host response to sepsis and developmental impact. Pediatrics 2010 1.62
17 The influence of developmental age on the early transcriptomic response of children with septic shock. Mol Med 2011 1.57
18 Time for a neonatal-specific consensus definition for sepsis. Pediatr Crit Care Med 2014 1.56
19 Extracellular heat shock protein-70 induces endotoxin tolerance in THP-1 cells. J Immunol 2006 1.55
20 IL-17-induced pulmonary pathogenesis during respiratory viral infection and exacerbation of allergic disease. Am J Pathol 2011 1.55
21 Fatal and near-fatal asthma in children: the critical care perspective. J Pediatr 2012 1.51
22 Clinical course of sepsis in children with acute leukemia admitted to the pediatric intensive care unit. Pediatr Crit Care Med 2011 1.51
23 Characteristics and outcomes of interhospital transfers from level II to level I pediatric intensive care units. Pediatr Crit Care Med 2006 1.50
24 New concepts of IL-10-induced lung fibrosis: fibrocyte recruitment and M2 activation in a CCL2/CCR2 axis. Am J Physiol Lung Cell Mol Physiol 2010 1.49
25 Feasibility and perceived benefits of a framework for physician-parent follow-up meetings after a child's death in the PICU. Crit Care Med 2014 1.49
26 A Multibiomarker-Based Model for Estimating the Risk of Septic Acute Kidney Injury. Crit Care Med 2015 1.49
27 Going back for more: an evaluation of clinical outcomes and characteristics of readmissions to a pediatric intensive care unit. Pediatr Crit Care Med 2007 1.44
28 Combined steroid treatment for congenital heart surgery improves oxygen delivery and reduces postbypass inflammatory mediator expression. Circulation 2003 1.42
29 Interleukin-27 is a novel candidate diagnostic biomarker for bacterial infection in critically ill children. Crit Care 2012 1.31
30 Contribution of MKP-1 regulation of p38 to endotoxin tolerance. Shock 2005 1.28
31 Inpatient health care utilization for children dependent on long-term mechanical ventilation. Pediatrics 2011 1.26
32 Effect of IL-10 on neutrophil recruitment and survival after Pseudomonas aeruginosa challenge. Am J Respir Cell Mol Biol 2008 1.23
33 Mechanisms and regulation of the gene-expression response to sepsis. Pediatrics 2010 1.22
34 Corticosteroids are associated with repression of adaptive immunity gene programs in pediatric septic shock. Am J Respir Crit Care Med 2014 1.20
35 Validation of the KDIGO acute kidney injury criteria in a pediatric critical care population. Intensive Care Med 2014 1.18
36 Identification of candidate serum biomarkers for severe septic shock-associated kidney injury via microarray. Crit Care 2011 1.16
37 Tracking the impact of the National Institutes of Health Clinical and Translational Science Awards on child health research: developing and evaluating a measurement strategy. Pediatr Res 2012 1.08
38 The A2A receptor mediates an endogenous regulatory pathway of cytokine expression in THP-1 cells. J Leukoc Biol 2002 1.07
39 An integrated microfluidic platform for in situ cellular cytokine secretion immunophenotyping. Lab Chip 2012 1.06
40 Epstein-Barr virus-induced hemophagocytic lymphohistiocytosis and X-linked lymphoproliferative disease: a mimicker of sepsis in the pediatric intensive care unit. Pediatrics 2007 1.00
41 Clinical implications and molecular mechanisms of immunoparalysis after cardiopulmonary bypass. J Thorac Cardiovasc Surg 2011 1.00
42 Critical care for pediatric asthma: wide care variability and challenges for study. Pediatr Crit Care Med 2012 0.99
43 Mitogen-activated protein kinase phosphatase 2 regulates the inflammatory response in sepsis. Infect Immun 2010 0.98
44 Ceramide-dependent PP2A regulation of TNFalpha-induced IL-8 production in respiratory epithelial cells. Am J Physiol Lung Cell Mol Physiol 2009 0.97
45 Immunoregulatory effects of regulated, lung-targeted expression of IL-10 in vivo. Am J Physiol Lung Cell Mol Physiol 2004 0.96
46 Incidence and Outcomes of Cardiopulmonary Resuscitation in PICUs. Crit Care Med 2016 0.96
47 Heat shock inhibits tnf-induced ICAM-1 expression in human endothelial cells via I kappa kinase inhibition. Shock 2002 0.95
48 Effect of interhospital transfer on resource utilization and outcomes at a tertiary pediatric intensive care unit. J Crit Care 2009 0.93
49 Heat shock-mediated regulation of MKP-1. Am J Physiol Cell Physiol 2005 0.92
50 Integrated nanoplasmonic sensing for cellular functional immunoanalysis using human blood. ACS Nano 2014 0.91
51 PP2A regulates upstream members of the c-jun N-terminal kinase mitogen-activated protein kinase signaling pathway. Shock 2008 0.89
52 Granulocyte-macrophage-colony-stimulating factor-dependent peritoneal macrophage responses determine survival in experimentally induced peritonitis and sepsis in mice. Shock 2008 0.85
53 Heat shock inhibits activation of NF-kappaB in the absence of heat shock factor-1. Biochem Biophys Res Commun 2002 0.85
54 The Accreditation Council for Graduate Medical Education proposed work hour regulations. Pediatr Crit Care Med 2011 0.85
55 Public participation in, and awareness about, medical research opportunities in the era of clinical and translational research. Clin Transl Sci 2013 0.85
56 Temporal and mechanistic effects of heat shock on LPS-mediated degradation of IkappaBalpha in macrophages. Inflammation 2002 0.84
57 Improving delivery of continuous renal replacement therapy: impact of a simulation-based educational intervention. Pediatr Crit Care Med 2013 0.84
58 The role of sphingosine-1-phosphate and ceramide-1-phosphate in calcium homeostasis. Curr Opin Investig Drugs 2008 0.84
59 Inhaled nitric oxide increases endothelin-1 levels: a potential cause of rebound pulmonary hypertension. Crit Care Med 2002 0.83
60 Tristetraprolin mediates radiation-induced TNF-α production in lung macrophages. PLoS One 2013 0.82
61 Mitogen-activated protein kinase phosphatase 2, MKP-2, regulates early inflammation in acute lung injury. Am J Physiol Lung Cell Mol Physiol 2012 0.82
62 Biology of sepsis: its relevance to pediatric nephrology. Pediatr Nephrol 2014 0.82
63 Heat shock inhibition of lipopolysaccharide-mediated tumor necrosis factor expression is associated with nuclear induction of MKP-1 and inhibition of mitogen-activated protein kinase activation. Crit Care Med 2004 0.81
64 Short-term modulation of interleukin-1beta signaling by hyperoxia: uncoupling of IkappaB kinase activation and NF-kappaB-dependent gene expression. Am J Physiol Lung Cell Mol Physiol 2003 0.79
65 Pathophysiology of Pediatric Multiple Organ Dysfunction Syndrome. Pediatr Crit Care Med 2017 0.78
66 Elucidating the role of reversible protein phosphorylation in sepsis-induced myocardial dysfunction. Shock 2009 0.78
67 Interleukin 10 overexpression alters survival in the setting of gram-negative pneumonia following lung contusion. Shock 2014 0.78
68 Hyperoxia prolongs tumor necrosis factor-alpha-mediated activation of NF-kappaB: role of IkappaB kinase. Shock 2002 0.78
69 Phosphatase inhibition leads to activation of IkappaB kinase in murine macrophages. Biochem Biophys Res Commun 2002 0.76
70 MAP Kinase Phosphatase-1 and Septic Shock. J Organ Dysfunct 2009 0.76
71 Management and Treatment Guidelines for Sepsis in Pediatric Patients. Open Inflamm J 2011 0.76
72 Approach to management of malignant hyperthermia-like syndrome in pediatric diabetes mellitus. Pediatr Crit Care Med 2006 0.75
73 Inherent Risk Factors for Nosocomial Infection in the Long Stay Critically Ill Child Without Known Baseline Immunocompromise: A Post Hoc Analysis of the CRISIS Trial. Pediatr Infect Dis J 2016 0.75
74 Refractory hypoxemia caused by hepatopulmonary syndrome: a case report. J Med Case Rep 2014 0.75
75 Tezosentan, another selective selection for pulmonary hypertension, or not? Pediatr Crit Care Med 2004 0.75
76 Bouncing back from inhaled nitric oxide. Pediatr Crit Care Med 2004 0.75
77 Cognitive Development 1 Year After Infantile Critical Pertussis. Pediatr Crit Care Med 2017 0.75
78 Functional Status of Neonatal and Pediatric Patients After Extracorporeal Membrane Oxygenation. Pediatr Crit Care Med 2017 0.75
79 Signal transduction overview. Crit Care Med 2005 0.75
80 Variability in Usual Care Mechanical Ventilation for Pediatric Acute Respiratory Distress Syndrome: Time for a Decision Support Protocol? Pediatr Crit Care Med 2017 0.75
81 Inherent Risk Factors for Nosocomial Infection in the Long Stay Critically Ill Child Without Known Baseline Immunocompromise: A Post -Hoc Analysis of the CRISIS Trial. Pediatr Infect Dis J 2016 0.75
82 Potential Acceptability of a Pediatric Ventilator Management Computer Protocol. Pediatr Crit Care Med 2017 0.75