Published in Dig Dis Sci on April 05, 2007
Analysis of fecal DNA methylation to detect gastrointestinal neoplasia. J Natl Cancer Inst (2009) 2.57
Next-generation stool DNA test accurately detects colorectal cancer and large adenomas. Gastroenterology (2011) 1.86
Methylation of TFPI2 in stool DNA: a potential novel biomarker for the detection of colorectal cancer. Cancer Res (2009) 1.80
Colorectal cancer: from prevention to personalized medicine. World J Gastroenterol (2014) 1.26
Epigenetic Alterations in Colorectal Cancer: Emerging Biomarkers. Gastroenterology (2015) 1.24
Identification of an epigenetic biomarker panel with high sensitivity and specificity for colorectal cancer and adenomas. Mol Cancer (2011) 1.22
Hypermethylated SFRP2 gene in fecal DNA is a high potential biomarker for colorectal cancer noninvasive screening. World J Gastroenterol (2008) 1.16
Long-range epigenetic silencing at 2q14.2 affects most human colorectal cancers and may have application as a non-invasive biomarker of disease. Br J Cancer (2009) 1.08
Novel candidate colorectal cancer biomarkers identified by methylation microarray-based scanning. Endocr Relat Cancer (2011) 1.03
Advances in epigenetic biomarker research in colorectal cancer. World J Gastroenterol (2014) 1.02
Epigenetic changes in colorectal cancer. Chin J Cancer (2011) 0.94
The complex roles of Wnt antagonists in RCC. Nat Rev Urol (2011) 0.89
DNA methylation analysis of SFRP2, GATA4/5, NDRG4 and VIM for the detection of colorectal cancer in fecal DNA. Oncol Lett (2014) 0.88
Fecal molecular markers for colorectal cancer screening. Gastroenterol Res Pract (2011) 0.82
Fecal DNA testing for colorectal cancer screening: Molecular targets and perspectives. World J Gastrointest Oncol (2015) 0.82
Cell-free nucleic acids as noninvasive biomarkers for colorectal cancer detection. Front Genet (2014) 0.80
Methylation-mediated loss of SFRP2 enhances melanoma cell invasion via Wnt signaling. Am J Transl Res (2016) 0.80
Use of NCCN Guidelines, Other Guidelines, and Biomarkers for Colorectal Cancer Screening. J Natl Compr Canc Netw (2016) 0.79
A pilot study on faecal MMP-9: a new noninvasive diagnostic marker of colorectal cancer. Br J Cancer (2016) 0.78
Quantitative profiling of CpG island methylation in human stool for colorectal cancer detection. Int J Colorectal Dis (2012) 0.78
DNA methylation analysis of secreted frizzled-related protein 2 gene for the early detection of colorectal cancer in fecal DNA. Niger Med J (2016) 0.77
Epigenetic inactivation of secreted frizzled-related protein 2 in esophageal squamous cell carcinoma. World J Gastroenterol (2012) 0.76
Genetic and epigenetic marker-based DNA test of stool is a promising approach for colorectal cancer screening. Yonsei Med J (2009) 0.76
DNA methylation assay for colorectal carcinoma. Cancer Biol Med (2017) 0.75
The defect of SFRP2 modulates an influx of extracellular calcium in B lymphocytes. BMC Res Notes (2014) 0.75
Cancer statistics, 2006. CA Cancer J Clin (2006) 30.71
The fundamental role of epigenetic events in cancer. Nat Rev Genet (2002) 30.05
Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands. Proc Natl Acad Sci U S A (1996) 29.54
Lessons from hereditary colorectal cancer. Cell (1996) 25.73
Epigenetic gene silencing in cancer - a mechanism for early oncogenic pathway addiction? Nat Rev Cancer (2006) 11.22
Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer. Nat Genet (2004) 7.78
A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer. Nat Genet (2002) 5.38
Detecting colorectal cancer in stool with the use of multiple genetic targets. J Natl Cancer Inst (2001) 2.93
Epigenetic changes in colorectal cancer. Cancer Metastasis Rev (2004) 2.35
Colorectal cancer screening by detection of altered human DNA in stool: feasibility of a multitarget assay panel. Gastroenterology (2000) 2.25
CpG island methylation in aberrant crypt foci of the colorectum. Am J Pathol (2002) 1.83
Methylation changes in faecal DNA: a marker for colorectal cancer screening? Lancet (2004) 1.80
Aberrantly methylated CDKN2A, MGMT, and MLH1 in colon polyps and in fecal DNA from patients with colorectal polyps. Clin Cancer Res (2005) 1.59
Methylation patterns define two types of hyperplastic polyp associated with colorectal cancer. Gut (2004) 1.53
Sensitivity and specificity of a stool DNA multitarget assay panel for the detection of advanced colorectal neoplasia. Clin Colorectal Cancer (2003) 1.35
Analysis of promoter methylation in stool: a novel method for the detection of colorectal cancer. Clin Gastroenterol Hepatol (2005) 1.27
Use of DNA from human stools to detect aberrant CpG island methylation of genes implicated in colorectal cancer. Cancer Epidemiol Biomarkers Prev (2004) 1.12
Detection of epigenetic changes in fecal DNA as a molecular screening test for colorectal cancer: a feasibility study. Clin Chem (2004) 1.00
Flexible sigmoidoscopy for colorectal cancer screening in the elderly. Dig Dis Sci (2005) 0.82
Retracted An integrated genomic-based approach to individualized treatment of patients with advanced-stage ovarian cancer. J Clin Oncol (2007) 5.77
MicroRNA miR-183 functions as an oncogene by targeting the transcription factor EGR1 and promoting tumor cell migration. Cancer Res (2010) 2.09
Reporting of the estimated glomerular filtration rate decreased creatinine clearance testing. Kidney Int (2012) 1.43
Primary and Secondary Thrombotic Microangiopathy Referred to a Single Plasma Exchange Center for Suspected Thrombotic Thrombocytopenic Purpura: 2000-2011. Am J Nephrol (2015) 1.38
Secular trends in acute dialysis after elective major surgery--1995 to 2009. CMAJ (2012) 1.33
Pristimerin induces apoptosis by targeting the proteasome in prostate cancer cells. J Cell Biochem (2008) 1.32
Perturbation of 14q32 miRNAs-cMYC gene network in osteosarcoma. Bone (2011) 1.31
Wild-type LRRK2 but not its mutant attenuates stress-induced cell death via ERK pathway. Neurobiol Dis (2008) 1.29
BAD phosphorylation determines ovarian cancer chemosensitivity and patient survival. Clin Cancer Res (2011) 1.17
Supramolecular hydrogel of a D-amino acid dipeptide for controlled drug release in vivo. Langmuir (2009) 1.13
Molecular and biochemical characterization of the Fe(III) chelate reductase gene family in Arabidopsis thaliana. Plant Cell Physiol (2005) 1.09
Genomewide microRNA down-regulation as a negative feedback mechanism in the early phases of liver regeneration. Hepatology (2011) 1.05
Reconstruction of rat calvarial defects with human mesenchymal stem cells and osteoblast-like cells in poly-lactic-co-glycolic acid scaffolds. Eur Cell Mater (2010) 1.05
Nok plays an essential role in maintaining the integrity of the outer nuclear layer in the zebrafish retina. Exp Eye Res (2006) 1.04
Effects of hindlimb unloading on ex vivo growth and osteogenic/adipogenic potentials of bone marrow-derived mesenchymal stem cells in rats. Stem Cells Dev (2008) 1.04
A BAC clone-based physical map of ovine major histocompatibility complex. Genomics (2006) 1.00
Morroniside and loganin extracted from Cornus officinalis have protective effects on rat mesangial cell proliferation exposed to advanced glycation end products by preventing oxidative stress. Can J Physiol Pharmacol (2006) 1.00
Mechanisms for osteogenic differentiation of human mesenchymal stem cells induced by fluid shear stress. Biomech Model Mechanobiol (2010) 0.98
Germline homeobox B13 (HOXB13) G84E mutation and prostate cancer risk in European descendants: a meta-analysis of 24,213 cases and 73, 631 controls. Eur Urol (2013) 0.95
Aquaporin water channels in transepithelial fluid transport. J Med Invest (2009) 0.94
ARHI, as a novel suppressor of cell growth and downregulated in human hepatocellular carcinoma, could contribute to hepatocarcinogenesis. Mol Carcinog (2009) 0.93
Evaluation of a rapid ELISA technique for detection of circulating antigens of Toxoplasma gondii. Microbiol Immunol (2008) 0.93
Dose-dependent differential mRNA target selection and regulation by let-7a-7f and miR-17-92 cluster microRNAs. RNA Biol (2012) 0.91
Decreased left middle temporal gyrus volume in antipsychotic drug-naive, first-episode schizophrenia patients and their healthy unaffected siblings. Schizophr Res (2013) 0.91
Expression of glioma stem cell marker CD133 and O6-methylguanine-DNA methyltransferase is associated with resistance to radiotherapy in gliomas. Oncol Rep (2011) 0.91
Sporadic obstructive hydrocephalus in Aqp4 null mice. J Neurosci Res (2009) 0.89
Expression of tumor necrosis factor alpha and neuronal apoptosis in the developing rat brain after neonatal stroke. Neurosci Lett (2006) 0.89
Activation of the EGFR/Akt/NF-κB/cyclinD1 survival signaling pathway in human cholesteatoma epithelium. Eur Arch Otorhinolaryngol (2013) 0.89
Stabilization of cellular properties and differentiation mutilpotential of human mesenchymal stem cells transduced with hTERT gene in a long-term culture. J Cell Biochem (2008) 0.89
Activation of protein kinase A and exchange protein directly activated by cAMP promotes adipocyte differentiation of human mesenchymal stem cells. PLoS One (2012) 0.88
Diabetes induces neural degeneration in nucleus ambiguus (NA) and attenuates heart rate control in OVE26 mice. Exp Neurol (2009) 0.87
Chronic intermittent hypoxia impairs heart rate responses to AMPA and NMDA and induces loss of glutamate receptor neurons in nucleus ambiguous of F344 rats. Am J Physiol Regul Integr Comp Physiol (2008) 0.87
P53 activation plays a crucial role in silibinin induced ROS generation via PUMA and JNK. Free Radic Res (2012) 0.86
Synthesis of biodiesel from a model waste oil feedstock using a carbon-based solid acid catalyst: reaction and separation. Bioresour Technol (2010) 0.86
Long noncoding RNA-LET, which is repressed by EZH2, inhibits cell proliferation and induces apoptosis of nasopharyngeal carcinoma cell. Med Oncol (2015) 0.85
Proliferation and osteogenesis of immortalized bone marrow-derived mesenchymal stem cells in porous polylactic glycolic acid scaffolds under perfusion culture. J Biomed Mater Res A (2010) 0.85
Computer-aided diagnosis of breast DCE-MRI images using bilateral asymmetry of contrast enhancement between two breasts. J Digit Imaging (2014) 0.85
The interaction between β1 integrins and ERK1/2 in osteogenic differentiation of human mesenchymal stem cells under fluid shear stress modelled by a perfusion system. J Tissue Eng Regen Med (2012) 0.85
Silibinin induced-autophagic and apoptotic death is associated with an increase in reactive oxygen and nitrogen species in HeLa cells. Free Radic Res (2011) 0.85
Mechanisms of bone anabolism regulated by statins. Biosci Rep (2012) 0.85
Different effects of intermittent and continuous fluid shear stresses on osteogenic differentiation of human mesenchymal stem cells. Biomech Model Mechanobiol (2011) 0.84
Anoctamin 1 calcium-activated chloride channel downregulates estrogen production in mouse ovarian granulosa cells. Endocrinology (2014) 0.84
Multifunctional divalent vancomycin: the fluorescent imaging and photodynamic antimicrobial properties for drug resistant bacteria. Chem Commun (Camb) (2010) 0.83
Improving the performance of computer-aided detection of subtle breast masses using an adaptive cueing method. Phys Med Biol (2012) 0.83
Isoalantolactone inhibits UM-SCC-10A cell growth via cell cycle arrest and apoptosis induction. PLoS One (2013) 0.83
Structural remodeling of nucleus ambiguus projections to cardiac ganglia following chronic intermittent hypoxia in C57BL/6J mice. J Comp Neurol (2008) 0.83
Ex vivo expansion, adipogenesis and neurogenesis of cryopreserved human bone marrow mesenchymal stem cells. Cell Biol Int (2006) 0.83
Improving performance of computer-aided detection of masses by incorporating bilateral mammographic density asymmetry: an assessment. Acad Radiol (2011) 0.83
Could the effect of modeled microgravity on osteogenic differentiation of human mesenchymal stem cells be reversed by regulation of signaling pathways? Biol Chem (2007) 0.82
Effects of microgravity modeled by large gradient high magnetic field on the osteogenic initiation of human mesenchymal stem cells. Stem Cell Rev (2010) 0.82
Low prevalence of work disability in early inflammatory arthritis (EIA) and early rheumatoid arthritis at enrollment into a multi-site registry: results from the catch cohort. Rheumatol Int (2012) 0.81
Impairment of baroreflex control of heart rate and structural changes of cardiac ganglia in conscious streptozotocin (STZ)-induced diabetic mice. Auton Neurosci (2010) 0.81
Development of neural stem cells at different sites of fetus brain of different gestational age. Int J Clin Exp Pathol (2013) 0.80
Using Congo red to report intracellular hydrogelation resulted from self-assembly of small molecules. Chem Commun (Camb) (2007) 0.80
Impairment of baroreflex control of heart rate in conscious transgenic mice of type 1 diabetes (OVE26). Auton Neurosci (2009) 0.80
Hollow fiber cell fishing with high performance liquid chromatography for screening bioactive compounds from traditional Chinese medicines. J Chromatogr A (2013) 0.80
Effect of spironolactone combined with angiotensin-converting enzyme inhibitors and/or angiotensin II receptor blockers on chronic glomerular disease. Exp Ther Med (2013) 0.79
Support of hMSCs transduced with TPO/FL genes to expansion of umbilical cord CD34+ cells in indirect co-culture. Cell Tissue Res (2006) 0.79
Biological, immunological and regenerative characteristics of placenta-derived mesenchymal stem cell isolated using a time-gradient attachment method. Stem Cell Res (2012) 0.79
Maternal diabetes increases small conductance Ca2+-activated K+ (SK) currents that alter action potential properties and excitability of cardiac motoneurons in the nucleus ambiguus. J Neurophysiol (2010) 0.79
Biocompatibility and bone-repairing effects: comparison between porous poly-lactic-co-glycolic acid and nano-hydroxyapatite/poly(lactic acid) scaffolds. J Biomed Nanotechnol (2014) 0.79
Bilateral sudden hearing loss following habitual abortion: a case report and review of literature. Int J Clin Exp Med (2013) 0.79
Improved stability and cell response by intrinsic cross-linking of multilayers from collagen I and oxidized glycosaminoglycans. Biomacromolecules (2014) 0.79
Actin microfilament mediates osteoblast Cbfa1 responsiveness to BMP2 under simulated microgravity. PLoS One (2013) 0.79
An interactive system for computer-aided diagnosis of breast masses. J Digit Imaging (2012) 0.79
Effect of pioglitazone on transdifferentiation of preosteoblasts from rat bone mesenchymal stem cells into adipocytes. J Huazhong Univ Sci Technolog Med Sci (2012) 0.79
Extracellular signal-regulated kinase1/2 activated by fluid shear stress promotes osteogenic differentiation of human bone marrow-derived mesenchymal stem cells through novel signaling pathways. Int J Biochem Cell Biol (2011) 0.78
P53-mediated GSH depletion enhanced the cytotoxicity of NO in silibinin-treated human cervical carcinoma HeLa cells. Free Radic Res (2012) 0.78
Sevelamer prescriptions after reporting of the Dialysis Clinical Outcomes Revisited (DCOR) trial findings: An analysis of 5,495 patients receiving maintenance dialysis in Ontario, Canada. Am J Kidney Dis (2011) 0.78
Preparation and characterization of thermo-responsive PDMS surfaces grafted with poly(N-isopropylacrylamide) by benzophenone-initiated photopolymerization. J Colloid Interface Sci (2009) 0.78
Facile fabrication of thermo-responsive and reduction-sensitive polymeric micelles for anticancer drug delivery. Macromol Biosci (2012) 0.78
Non-biologic disease-modifying antirheumatic drugs (DMARDs) improve pain in inflammatory arthritis (IA): a systematic literature review of randomized controlled trials. Rheumatol Int (2013) 0.78
Degeneration of vagal efferent axons and terminals in cardiac ganglia of aged rats. J Comp Neurol (2007) 0.77
Association of 8q24 rs13281615A > G polymorphism with breast cancer risk: evidence from 40,762 cases and 50,380 controls. Mol Biol Rep (2013) 0.77
Proliferation and multi-differentiation potentials of human mesenchymal stem cells on thermoresponsive PDMS surfaces grafted with PNIPAAm. Biosci Rep (2009) 0.77
The risk of perioperative bleeding in patients with chronic kidney disease: a systematic review and meta-analysis. Ann Surg (2013) 0.77
Integrating overlapping structures and background information of words significantly improves biological sequence comparison. PLoS One (2011) 0.77
Association of COMT Val158Met polymorphism with wearing-off susceptibility in Parkinson's disease. Neurol Sci (2014) 0.77
Distribution of metals and brominated flame retardants (BFRs) in sediments, soils and plants from an informal e-waste dismantling site, South China. Environ Sci Pollut Res Int (2014) 0.77
Maternal diabetes increases large conductance Ca2+-activated K+ outward currents that alter action potential properties but do not contribute to attenuated excitability of parasympathetic cardiac motoneurons in the nucleus ambiguus of neonatal mice. Am J Physiol Regul Integr Comp Physiol (2011) 0.76
Improving protein structural class prediction using novel combined sequence information and predicted secondary structural features. J Comput Chem (2011) 0.76
Investigation of the antimicrobial activity and biocompatibility of magnesium alloy coated with HA and antimicrobial peptide. J Mater Sci Mater Med (2015) 0.76
In vitro evaluation of random and aligned polycaprolactone/gelatin fibers via electrospinning for bone tissue engineering. J Biomater Sci Polym Ed (2015) 0.76
Numerical study of magnetoacoustic signal generation with magnetic induction based on inhomogeneous conductivity anisotropy. Comput Math Methods Med (2013) 0.76
Effects of BMP-2 and FGF2 on the osteogenesis of bone marrow-derived mesenchymal stem cells in hindlimb-unloaded rats. Cell Biochem Biophys (2014) 0.76
Comparative analysis of gene expression at early seedling stage between a rice hybrid and its parents using a cDNA microarray of 9198 uni-sequences. Sci China C Life Sci (2006) 0.76
Exchange protein activated by cyclic adenosine monophosphate regulates the switch between adipogenesis and osteogenesis of human mesenchymal stem cells through increasing the activation of phosphatidylinositol 3-kinase. Int J Biochem Cell Biol (2012) 0.76
Bioinspired supramolecular confinement of luminol and heme proteins to enhance the chemiluminescent quantum yield. Chemistry (2009) 0.76
Sequence comparison via polar coordinates representation and curve tree. J Theor Biol (2011) 0.76
Effects of ectopic expression of human telomerase reverse transcriptase on immortalization of feather keratinocyte stem cells. J Exp Zool B Mol Dev Evol (2009) 0.76
Studies on culture and osteogenic induction of human mesenchymal stem cells under CO2-independent conditions. Astrobiology (2013) 0.75
Correlation between surfactant protein B mRNA expression and neonatal respiratory distress syndrome. Exp Ther Med (2012) 0.75
Three-dimensional honeycomb-patterned chitosan/poly(L-lactic acid) scaffolds with improved mechanical and cell compatibility. J Biomed Mater Res A (2011) 0.75
Comment on "molecular dynamics simulation of the liquid/vapor interface of aqueous ethanol solutions as a function of concentration". J Phys Chem B (2005) 0.75
Monoclinic Hydroxyapatite Nanoplates Hybrid Composite with Improved Compressive Strength, and Porosity for Bone Defect Repair: Biomimetic Synthesis and Characterization. J Nanosci Nanotechnol (2016) 0.75
[Novel scaffold materials for tissue engineering]. Sheng Wu Yi Xue Gong Cheng Xue Za Zhi (2002) 0.75
A Semi-Automatic Coronary Artery Segmentation Framework Using Mechanical Simulation. J Med Syst (2015) 0.75
Two-fluid model based on the lattice Boltzmann equation. Phys Rev E Stat Nonlin Soft Matter Phys (2005) 0.75
OS 33-03 SERUM N1-METHYLNICOTINAMIDE IS ASSOCIATED WITH OBESITY AND DIABETES IN CHINESE. J Hypertens (2016) 0.75
[Ectopic internal carotid artery presenting as an oropharyngeal mass]. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi (2015) 0.75