Published in Am J Med Genet B Neuropsychiatr Genet on June 05, 2007
The GSK3 hypothesis of Alzheimer's disease. J Neurochem (2007) 3.16
Clinical epidemiology of Alzheimer's disease: assessing sex and gender differences. Clin Epidemiol (2014) 1.56
Extended tracts of homozygosity identify novel candidate genes associated with late-onset Alzheimer's disease. Neurogenetics (2009) 1.50
PPARgamma agonists as therapeutics for the treatment of Alzheimer's disease. Neurotherapeutics (2008) 1.36
Deletion of Irs2 reduces amyloid deposition and rescues behavioural deficits in APP transgenic mice. Biochem Biophys Res Commun (2009) 1.28
Intermediate phenotypes identify divergent pathways to Alzheimer's disease. PLoS One (2010) 1.11
Concerted perturbation observed in a hub network in Alzheimer's disease. PLoS One (2012) 1.00
PPARs in Alzheimer's Disease. PPAR Res (2008) 0.88
Association of CETP polymorphisms with the risk of vascular dementia and white matter lesions. J Neural Transm (Vienna) (2009) 0.88
Impact and Therapeutic Potential of PPARs in Alzheimer's Disease. Curr Neuropharmacol (2011) 0.82
Neuroprotective mechanisms of peroxisome proliferator-activated receptor agonists in Alzheimer's disease. Naunyn Schmiedebergs Arch Pharmacol (2011) 0.82
PPARγ2 polymorphism and human health. PPAR Res (2009) 0.82
The relationship of diet and acne: A review. Dermatoendocrinol (2009) 0.79
Pharmacogenomics in type 2 diabetes: oral antidiabetic drugs. Pharmacogenomics J (2016) 0.75
Lack of Genetic Associations of PPAR-γ and PGC-1α with Alzheimer's Disease and Parkinson's Disease with Dementia. Dement Geriatr Cogn Dis Extra (2013) 0.75
Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. Nature (2009) 33.26
Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease. Nat Genet (2009) 15.15
Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants. Nat Genet (2007) 12.62
Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls. Nature (2010) 12.27
TREM2 variants in Alzheimer's disease. N Engl J Med (2012) 11.35
Identification of loci associated with schizophrenia by genome-wide association and follow-up. Nat Genet (2008) 10.52
Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder. Nat Genet (2008) 10.49
Wake-up call for British psychiatry. Br J Psychiatry (2008) 10.30
Genome-wide analysis of genetic loci associated with Alzheimer disease. JAMA (2010) 9.52
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease. Nat Genet (2011) 9.23
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nat Genet (2013) 8.02
Genome-wide association analysis identifies 13 new risk loci for schizophrenia. Nat Genet (2013) 7.44
Genome scan meta-analysis of schizophrenia and bipolar disorder, part II: Schizophrenia. Am J Hum Genet (2003) 6.63
Microduplications of 16p11.2 are associated with schizophrenia. Nat Genet (2009) 6.13
Gene ontology analysis of GWA study data sets provides insights into the biology of bipolar disorder. Am J Hum Genet (2009) 5.98
Rare chromosomal deletions and duplications in attention-deficit hyperactivity disorder: a genome-wide analysis. Lancet (2010) 5.78
Synaptic, transcriptional and chromatin genes disrupted in autism. Nature (2014) 5.30
Comparative genome hybridization suggests a role for NRXN1 and APBA2 in schizophrenia. Hum Mol Genet (2007) 5.28
Protective variant for hippocampal atrophy identified by whole exome sequencing. Ann Neurol (2015) 5.10
Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease. Arch Neurol (2007) 5.09
Support for the involvement of large copy number variants in the pathogenesis of schizophrenia. Hum Mol Genet (2009) 4.52
The beginning of the end for the Kraepelinian dichotomy. Br J Psychiatry (2005) 4.51
The Kraepelinian dichotomy - going, going... but still not gone. Br J Psychiatry (2010) 4.47
Genes for schizophrenia and bipolar disorder? Implications for psychiatric nosology. Schizophr Bull (2005) 3.93
Association of plasma clusterin concentration with severity, pathology, and progression in Alzheimer disease. Arch Gen Psychiatry (2010) 3.64
Chromosome 9p21 in sporadic amyotrophic lateral sclerosis in the UK and seven other countries: a genome-wide association study. Lancet Neurol (2010) 3.61
Genes for schizophrenia? Recent findings and their pathophysiological implications. Lancet (2003) 3.61
Discovery and statistical genotyping of copy-number variation from whole-exome sequencing depth. Am J Hum Genet (2012) 3.50
Genome-wide association identifies a common variant in the reelin gene that increases the risk of schizophrenia only in women. PLoS Genet (2008) 3.33
Functional annotation of the human brain methylome identifies tissue-specific epigenetic variation across brain and blood. Genome Biol (2012) 3.31
Conceptual framework for personal recovery in mental health: systematic review and narrative synthesis. Br J Psychiatry (2011) 3.29
The GSK3 hypothesis of Alzheimer's disease. J Neurochem (2007) 3.16
The South London and Maudsley NHS Foundation Trust Biomedical Research Centre (SLAM BRC) case register: development and descriptive data. BMC Psychiatry (2009) 3.15
Cis-acting variation in the expression of a high proportion of genes in human brain. Hum Genet (2003) 3.07
Analysis of copy number variations at 15 schizophrenia-associated loci. Br J Psychiatry (2013) 3.01
Phenotypic and genetic complexity of psychosis. Invited commentary on ... Schizophrenia: a common disease caused by multiple rare alleles. Br J Psychiatry (2007) 2.97
Rethinking psychosis: the disadvantages of a dichotomous classification now outweigh the advantages. World Psychiatry (2007) 2.82
Evidence for novel susceptibility genes for late-onset Alzheimer's disease from a genome-wide association study of putative functional variants. Hum Mol Genet (2007) 2.73
Genome-wide association study identifies genetic variation in neurocan as a susceptibility factor for bipolar disorder. Am J Hum Genet (2011) 2.71
Improved detection of common variants associated with schizophrenia and bipolar disorder using pleiotropy-informed conditional false discovery rate. PLoS Genet (2013) 2.68
Delta-like 1 is necessary for the generation of marginal zone B cells but not T cells in vivo. Nat Immunol (2004) 2.63
Operation of the schizophrenia susceptibility gene, neuregulin 1, across traditional diagnostic boundaries to increase risk for bipolar disorder. Arch Gen Psychiatry (2005) 2.58
Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease. PLoS One (2010) 2.57
Agreement between maternal report and antenatal records for a range of pre and peri-natal factors: the influence of maternal and child characteristics. Early Hum Dev (2006) 2.56
Is MCI really just early dementia? A systematic review of conversion studies. Int Psychogeriatr (2004) 2.54
Meta-analysis shows significant association between dopamine system genes and attention deficit hyperactivity disorder (ADHD). Hum Mol Genet (2006) 2.48
Genome-wide analysis of copy number variants in attention deficit hyperactivity disorder: the role of rare variants and duplications at 15q13.3. Am J Psychiatry (2012) 2.48
The dementias. Lancet (2002) 2.42
Paternal age and risk for schizophrenia. Br J Psychiatry (2003) 2.34
Neurexin 1 (NRXN1) deletions in schizophrenia. Schizophr Bull (2009) 2.25
Effects of differential genotyping error rate on the type I error probability of case-control studies. Hum Hered (2006) 2.21
Common variants at VRK2 and TCF4 conferring risk of schizophrenia. Hum Mol Genet (2011) 2.21
Investigating the contribution of common genetic variants to the risk and pathogenesis of ADHD. Am J Psychiatry (2012) 2.20
A genome-wide association study for late-onset Alzheimer's disease using DNA pooling. BMC Med Genomics (2008) 2.20
Risk of psychopathology in adolescent offspring of mothers with psychopathology and recurrent depression. Br J Psychiatry (2012) 2.19
Polymorphism of the 5-HT transporter and response to antidepressants: randomised controlled trial. Br J Psychiatry (2011) 2.18
Genetic variation of brain-derived neurotrophic factor (BDNF) in bipolar disorder: case-control study of over 3000 individuals from the UK. Br J Psychiatry (2006) 2.16
GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer's disease. Neuron (2013) 2.13