Jonathan M Boulter

Author PubWeight™ 24.42‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Directed evolution of human T-cell receptors with picomolar affinities by phage display. Nat Biotechnol 2005 2.97
2 Structural and kinetic basis for heightened immunogenicity of T cell vaccines. J Exp Med 2005 2.22
3 Human TCR-binding affinity is governed by MHC class restriction. J Immunol 2007 2.02
4 TCR affinity and negative regulation limit autoimmunity. Nat Med 2004 1.94
5 The CD8 T cell coreceptor exhibits disproportionate biological activity at extremely low binding affinities. J Biol Chem 2003 1.92
6 Design of soluble recombinant T cell receptors for antigen targeting and T cell inhibition. J Biol Chem 2004 1.29
7 Enhanced immunogenicity of CTL antigens through mutation of the CD8 binding MHC class I invariant region. Eur J Immunol 2007 1.24
8 Crystal structures of high affinity human T-cell receptors bound to peptide major histocompatibility complex reveal native diagonal binding geometry. Protein Eng Des Sel 2007 1.19
9 T cell receptor engagement of peptide-major histocompatibility complex class I does not modify CD8 binding. Mol Immunol 2008 1.18
10 Crystal structure of HLA-A*2402 complexed with a telomerase peptide. Eur J Immunol 2006 0.98
11 Computational design and crystal structure of an enhanced affinity mutant human CD8 alphaalpha coreceptor. Proteins 2007 0.93
12 Increased Peptide Contacts Govern High Affinity Binding of a Modified TCR Whilst Maintaining a Native pMHC Docking Mode. Front Immunol 2013 0.88
13 Functional and biophysical characterization of an HLA-A*6801-restricted HIV-specific T cell receptor. Eur J Immunol 2007 0.87
14 Novel CD8+ T cell antagonists based on beta 2-microglobulin. J Biol Chem 2002 0.87
15 Amplification and one-step expression cloning of human T cell receptor genes. Anal Biochem 2004 0.85
16 Purification and characterization of transporter proteins from human erythrocyte membrane. Methods Mol Biol 2003 0.82
17 Crystallization and preliminary X-ray structural studies of a high-affinity CD8alphaalpha co-receptor to pMHC. Acta Crystallogr Sect F Struct Biol Cryst Commun 2005 0.81
18 Production of a soluble disulfide bond-linked TCR in the cytoplasm of Escherichia coli trxB gor mutants. Mol Biotechnol 2010 0.78
19 Complete mapping of a novel HLA A*6801-restricted HIV-1 Tat epitope directly with a rapid modified enzyme-linked immunospot assay. AIDS 2002 0.78