| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Targeting of Bcl-2 to the mitochondrial outer membrane by a COOH-terminal signal anchor sequence.
|
J Biol Chem
|
1993
|
3.21
|
|
2
|
Chemokine monocyte chemoattractant protein-1 is expressed by astrocytes after mechanical injury to the brain.
|
J Immunol
|
1996
|
1.84
|
|
3
|
Pro-regenerative properties of cytokine-activated astrocytes.
|
J Neurochem
|
2004
|
1.83
|
|
4
|
Matrix metalloproteinase-9/gelatinase B is required for process outgrowth by oligodendrocytes.
|
J Neurosci
|
1999
|
1.81
|
|
5
|
Induction and intracellular regulation of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) mediated apotosis in human malignant glioma cells.
|
Cancer Res
|
2001
|
1.70
|
|
6
|
Interferon beta-1b decreases the migration of T lymphocytes in vitro: effects on matrix metalloproteinase-9.
|
Ann Neurol
|
1996
|
1.51
|
|
7
|
Inhibition of growth of established human glioma cell lines by modulators of the protein kinase-C system.
|
J Neurosurg
|
1990
|
1.46
|
|
8
|
Reactive astrogliosis in the neonatal mouse brain and its modulation by cytokines.
|
J Neurosci
|
1994
|
1.44
|
|
9
|
P2X7-like receptor activation in astrocytes increases chemokine monocyte chemoattractant protein-1 expression via mitogen-activated protein kinase.
|
J Neurosci
|
2001
|
1.38
|
|
10
|
The identification of novel therapeutic targets for the treatment of malignant brain tumors.
|
Cancer Lett
|
2000
|
1.36
|
|
11
|
Hallervorden-Spatz disease: cysteine accumulation and cysteine dioxygenase deficiency in the globus pallidus.
|
Ann Neurol
|
1985
|
1.26
|
|
12
|
Cyclin-dependent kinase-5 prevents neuronal apoptosis through ERK-mediated upregulation of Bcl-2.
|
Cell Death Differ
|
2005
|
1.25
|
|
13
|
Interleukin-1 is a key regulator of matrix metalloproteinase-9 expression in human neurons in culture and following mouse brain trauma in vivo.
|
J Neurosci Res
|
2000
|
1.21
|
|
14
|
PTEN/MMAC1/TEP1 in signal transduction and tumorigenesis.
|
Eur J Biochem
|
1999
|
1.20
|
|
15
|
Biology of adult human microglia in culture: comparisons with peripheral blood monocytes and astrocytes.
|
J Neuropathol Exp Neurol
|
1992
|
1.19
|
|
16
|
The clinical response to minocycline in multiple sclerosis is accompanied by beneficial immune changes: a pilot study.
|
Mult Scler
|
2007
|
1.18
|
|
17
|
Central nervous system-initiated inflammation and neurotrophism in trauma: IL-1 beta is required for the production of ciliary neurotrophic factor.
|
J Immunol
|
2000
|
1.17
|
|
18
|
Overexpression of 2',3'-cyclic nucleotide 3'-phosphodiesterase in transgenic mice alters oligodendrocyte development and produces aberrant myelination.
|
Mol Cell Neurosci
|
1996
|
1.17
|
|
19
|
Idiopathic Parkinson's disease, progressive supranuclear palsy and glutathione metabolism in the substantia nigra of patients.
|
Neurosci Lett
|
1986
|
1.17
|
|
20
|
Microglial production of TNF-alpha is induced by activated T lymphocytes. Involvement of VLA-4 and inhibition by interferonbeta-1b.
|
J Clin Invest
|
1997
|
1.15
|
|
21
|
Interleukin-1 beta is required for the early evolution of reactive astrogliosis following CNS lesion.
|
J Neuropathol Exp Neurol
|
2001
|
1.15
|
|
22
|
Involvement of p21(Waf1/Cip1) in protein kinase C alpha-induced cell cycle progression.
|
Mol Cell Biol
|
2000
|
1.13
|
|
23
|
Differential activation of ERKs to focal adhesions by PKC epsilon is required for PMA-induced adhesion and migration of human glioma cells.
|
Oncogene
|
2001
|
1.12
|
|
24
|
HIV-1 Tat neurotoxicity is prevented by matrix metalloproteinase inhibitors.
|
Ann Neurol
|
2001
|
1.04
|
|
25
|
Oligodendrocytes utilize a matrix metalloproteinase, MMP-9, to extend processes along an astrocyte extracellular matrix.
|
Glia
|
1998
|
1.03
|
|
26
|
Marked inhibition of tumor growth in a malignant glioma tumor model by a novel synthetic matrix metalloproteinase inhibitor AG3340.
|
Clin Cancer Res
|
1999
|
1.03
|
|
27
|
Astrocytes attenuate oligodendrocyte death in vitro through an alpha(6) integrin-laminin-dependent mechanism.
|
Glia
|
2001
|
1.01
|
|
28
|
Amino acids, glutathione, and glutathione transferase activity in the brains of patients with Alzheimer's disease.
|
Ann Neurol
|
1987
|
1.01
|
|
29
|
Glatiramer acetate in combination with minocycline in patients with relapsing--remitting multiple sclerosis: results of a Canadian, multicenter, double-blind, placebo-controlled trial.
|
Mult Scler
|
2009
|
1.01
|
|
30
|
Glioma invasion in vitro: regulation by matrix metalloprotease-2 and protein kinase C.
|
Clin Exp Metastasis
|
1996
|
1.00
|
|
31
|
Attenuation of astroglial reactivity by interleukin-10.
|
J Neurosci
|
1996
|
0.98
|
|
32
|
Enhanced protein kinase C activity correlates with the growth rate of malignant gliomas in vitro.
|
Neurosurgery
|
1991
|
0.97
|
|
33
|
Mechanisms of IL-10 production in human microglia-T cell interaction.
|
J Immunol
|
1999
|
0.96
|
|
34
|
Infection of primary cultures of human neural cells by human coronaviruses 229E and OC43.
|
J Virol
|
1997
|
0.95
|
|
35
|
Chemokine-enhanced migration of human peripheral blood mononuclear cells is antagonized by interferon beta-1b through an effect on matrix metalloproteinase-9.
|
J Neuroimmunol
|
1997
|
0.95
|
|
36
|
Astrogliosis in the neonatal and adult murine brain post-trauma: elevation of inflammatory cytokines and the lack of requirement for endogenous interferon-gamma.
|
J Neurosci
|
1997
|
0.94
|
|
37
|
Mechanisms of glioma invasion: role of matrix-metalloproteinases.
|
Can J Neurol Sci
|
1997
|
0.92
|
|
38
|
Protein kinase C activity correlates with the growth rate of malignant gliomas: Part II. Effects of glioma mitogens and modulators of protein kinase C.
|
Neurosurgery
|
1992
|
0.90
|
|
39
|
Interferon beta-1b increases interleukin-10 in a model of T cell-microglia interaction: relevance to MS.
|
Neurology
|
2000
|
0.90
|
|
40
|
Partial protection from the dopaminergic neurotoxin N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine by four different antioxidants in the mouse.
|
Neurosci Lett
|
1985
|
0.90
|
|
41
|
Interferon-beta is a potent promoter of nerve growth factor production by astrocytes.
|
J Neurochem
|
1997
|
0.89
|
|
42
|
Induction of RANTES expression by astrocytes and astrocytoma cell lines.
|
J Neuroimmunol
|
1996
|
0.89
|
|
43
|
Mitogenic signaling and the relationship to cell cycle regulation in astrocytomas.
|
J Neurooncol
|
2001
|
0.88
|
|
44
|
Origin of contralateral reactive gliosis in surgically injured rat cerebral cortex.
|
Brain Res
|
1991
|
0.87
|
|
45
|
Astrocyte reactivity in neonatal mice: apparent dependence on the presence of reactive microglia/macrophages.
|
Glia
|
1996
|
0.86
|
|
46
|
Antigen presentation by human fetal astrocytes with the cooperative effect of microglia or the microglial-derived cytokine IL-1.
|
J Neurosci
|
1995
|
0.84
|
|
47
|
Protein kinase C and growth regulation of malignant gliomas.
|
Can J Neurol Sci
|
1995
|
0.83
|
|
48
|
Migratory behavior of lymphocytes isolated from multiple sclerosis patients: effects of interferon beta-1b therapy.
|
Ann Neurol
|
1999
|
0.83
|
|
49
|
Cytokine production in T lymphocyte-microglia interaction is attenuated by glatiramer acetate: a mechanism for therapeutic efficacy in multiple sclerosis.
|
Mult Scler
|
2002
|
0.83
|
|
50
|
Nigrostriatal dopaminergic neurons remain undamaged in rats given high doses of L-DOPA and carbidopa chronically.
|
J Neurochem
|
1984
|
0.83
|
|
51
|
Signal transduction for proliferation of glioma cells in vitro occurs predominantly through a protein kinase C-mediated pathway.
|
Brain Res
|
1996
|
0.83
|
|
52
|
Protein kinase C inhibitors suppress cell growth in established and low-passage glioma cell lines. A comparison between staurosporine and tamoxifen.
|
Neurosurgery
|
1993
|
0.82
|
|
53
|
Cytokine production consequent to T cell--microglia interaction: the PMA/IFN gamma-treated U937 cells display similarities to human microglia.
|
J Neurosci Methods
|
2001
|
0.82
|
|
54
|
Alpha-tocopherol and beta-carotene do not protect marmosets against the dopaminergic neurotoxicity of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
|
J Neurol Sci
|
1987
|
0.82
|
|
55
|
Adenovirus-mediated wild-type p53 gene transfer and overexpression induces apoptosis of human glioma cells independent of endogenous p53 status.
|
J Neuropathol Exp Neurol
|
1997
|
0.82
|
|
56
|
Astrocytes promote process outgrowth by adult human oligodendrocytes in vitro through interaction between bFGF and astrocyte extracellular matrix.
|
Glia
|
1996
|
0.82
|
|
57
|
Astrocytes and catalase prevent the toxicity of catecholamines to oligodendrocytes.
|
Brain Res
|
1994
|
0.81
|
|
58
|
Monoamine oxidase B, smoking, and Parkinson's disease.
|
J Neurol Sci
|
1986
|
0.81
|
|
59
|
Asymptomatic striatal dopamine depletion: PET scans in unilateral MPTP monkeys.
|
Synapse
|
1988
|
0.81
|
|
60
|
Staurosporine differentially inhibits glioma versus non-glioma cell lines.
|
J Neurooncol
|
1993
|
0.80
|
|
61
|
Immune-mediated neurodegeneration and neuroprotection in MS.
|
Int MS J
|
2003
|
0.80
|
|
62
|
Production of soluble autocrine inhibitory factors by human glioma cell lines.
|
J Neurol Sci
|
1992
|
0.79
|
|
63
|
Oligodendrocytes and myelin.
|
Neurol Clin
|
1995
|
0.79
|
|
64
|
The promoting effects of bFGF and astrocyte extracellular matrix on process outgrowth by adult human oligodendrocytes are mediated by protein kinase C.
|
Brain Res
|
1997
|
0.79
|
|
65
|
Paraquat and two endogenous analogues of the neurotoxic substance N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine do not damage dopaminergic nigrostriatal neurons in the mouse.
|
Neurosci Lett
|
1986
|
0.79
|
|
66
|
Depletion of glutathione in brainstem of mice caused by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine is prevented by antioxidant pretreatment.
|
Neurosci Lett
|
1986
|
0.79
|
|
67
|
Immune and non-immune actions of interferon-beta-Ib on primary human neural cells.
|
Mult Scler
|
1995
|
0.78
|
|
68
|
3T deep gray matter T2 hypointensity correlates with disability over time in stable relapsing-remitting multiple sclerosis: a 3-year pilot study.
|
J Neurol Sci
|
2010
|
0.78
|
|
69
|
Effects of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and its metabolite, N-methyl-4-phenylpyridinium ion, on dopaminergic nigrostriatal neurons in the mouse.
|
Neurosci Lett
|
1985
|
0.78
|
|
70
|
TGF-B2 and soluble p55 TNFR modulate VCAM-1 expression in glioma cells and brain derived endothelial cells.
|
J Neuroimmunol
|
1997
|
0.78
|
|
71
|
The astrocyte mitogen, tumor necrosis factor-alpha, inhibits the proliferative effect of more potent adult human astrocyte mitogens, gamma-interferon and activated T-lymphocyte supernatants.
|
Brain Res
|
1994
|
0.78
|
|
72
|
The failure of morphine to depress selectively non-adrenergic neural inhibition of the guinea-pig taenia caeci.
|
J Pharm Pharmacol
|
1983
|
0.77
|
|
73
|
Microglial reaction in some CNS nuclei following nerves transection in BALB/c and interferon-gamma gene knockout mice.
|
Neurosci Lett
|
1999
|
0.77
|
|
74
|
Protein kinase C and growth regulation of pituitary adenomas.
|
Acta Neurochir Suppl
|
1996
|
0.77
|
|
75
|
Manipulation of glutathione contents fails to alter dopaminergic nigrostriatal neurotoxicity of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the mouse.
|
Neurosci Lett
|
1986
|
0.77
|
|
76
|
alpha2,3-sialyltransferase mRNA and alpha2,3-linked glycoprotein sialylation are increased in malignant gliomas.
|
Brain Res
|
1997
|
0.77
|
|
77
|
Protein kinase C activity and intracellular distribution in surgically excised human epileptic neocortex.
|
Brain Res
|
1991
|
0.76
|
|
78
|
Malignant glioma-derived soluble factors regulate proliferation of normal adult human astrocytes.
|
J Neuropathol Exp Neurol
|
1992
|
0.76
|
|
79
|
Apoptosis is induced in glioma cells by antisense oligonucleotides to protein kinase C alpha and is enhanced by cycloheximide.
|
Neuroreport
|
1998
|
0.76
|
|
80
|
Differential role for protein kinase C-mediated signaling in the proliferation of medulloblastoma cell lines.
|
Int J Oncol
|
1998
|
0.76
|
|
81
|
The therapeutic potential of chemokine-toxin fusion proteins.
|
IDrugs
|
2001
|
0.76
|
|
82
|
Neurochemical abnormalities in brains of renal failure patients treated by repeated hemodialysis.
|
J Neurochem
|
1985
|
0.76
|
|
83
|
Protein kinase C isoform alpha overexpression in C6 glioma cells and its role in cell proliferation.
|
J Neurooncol
|
1995
|
0.76
|
|
84
|
Human fetal Schwann cells in culture: phenotypic expressions and proliferative capability.
|
J Neurosci Res
|
1989
|
0.75
|
|
85
|
Chronic organic manganese administration in the rat does not damage dopaminergic nigrostriatal neurons.
|
Neurotoxicology
|
1986
|
0.75
|
|
86
|
Glioma invasion.
|
J Neurosurg
|
2001
|
0.75
|
|
87
|
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) does not destroy nigrostriatal neurons in the scorbutic guinea pig.
|
Life Sci
|
1985
|
0.75
|
|
88
|
Tissue culture evidence for a circulating neurotoxin in Huntington's chorea.
|
J Neurol Sci
|
1987
|
0.75
|
|
89
|
Chronic treatment with ACTH1-24 does not produce permanent damage to the developing rat brain.
|
Brain Res
|
1985
|
0.75
|
|
90
|
Identification of GTP-binding proteins in myelin and oligodendrocyte membranes.
|
J Neurosci Res
|
1990
|
0.75
|
|
91
|
Is a circulating neurotoxin involved in the pathogenesis of Huntington's chorea?
|
J Neurol Sci
|
1985
|
0.75
|
|
92
|
Inability to produce a model of dialysis encephalopathy in the rat by aluminum administration.
|
Neurochem Res
|
1987
|
0.75
|