V W Yong

Author PubWeight™ 84.64‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Targeting of Bcl-2 to the mitochondrial outer membrane by a COOH-terminal signal anchor sequence. J Biol Chem 1993 3.21
2 Chemokine monocyte chemoattractant protein-1 is expressed by astrocytes after mechanical injury to the brain. J Immunol 1996 1.84
3 Pro-regenerative properties of cytokine-activated astrocytes. J Neurochem 2004 1.83
4 Matrix metalloproteinase-9/gelatinase B is required for process outgrowth by oligodendrocytes. J Neurosci 1999 1.81
5 Induction and intracellular regulation of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) mediated apotosis in human malignant glioma cells. Cancer Res 2001 1.70
6 Interferon beta-1b decreases the migration of T lymphocytes in vitro: effects on matrix metalloproteinase-9. Ann Neurol 1996 1.51
7 Inhibition of growth of established human glioma cell lines by modulators of the protein kinase-C system. J Neurosurg 1990 1.46
8 Reactive astrogliosis in the neonatal mouse brain and its modulation by cytokines. J Neurosci 1994 1.44
9 P2X7-like receptor activation in astrocytes increases chemokine monocyte chemoattractant protein-1 expression via mitogen-activated protein kinase. J Neurosci 2001 1.38
10 The identification of novel therapeutic targets for the treatment of malignant brain tumors. Cancer Lett 2000 1.36
11 Hallervorden-Spatz disease: cysteine accumulation and cysteine dioxygenase deficiency in the globus pallidus. Ann Neurol 1985 1.26
12 Cyclin-dependent kinase-5 prevents neuronal apoptosis through ERK-mediated upregulation of Bcl-2. Cell Death Differ 2005 1.25
13 Interleukin-1 is a key regulator of matrix metalloproteinase-9 expression in human neurons in culture and following mouse brain trauma in vivo. J Neurosci Res 2000 1.21
14 PTEN/MMAC1/TEP1 in signal transduction and tumorigenesis. Eur J Biochem 1999 1.20
15 Biology of adult human microglia in culture: comparisons with peripheral blood monocytes and astrocytes. J Neuropathol Exp Neurol 1992 1.19
16 The clinical response to minocycline in multiple sclerosis is accompanied by beneficial immune changes: a pilot study. Mult Scler 2007 1.18
17 Central nervous system-initiated inflammation and neurotrophism in trauma: IL-1 beta is required for the production of ciliary neurotrophic factor. J Immunol 2000 1.17
18 Overexpression of 2',3'-cyclic nucleotide 3'-phosphodiesterase in transgenic mice alters oligodendrocyte development and produces aberrant myelination. Mol Cell Neurosci 1996 1.17
19 Idiopathic Parkinson's disease, progressive supranuclear palsy and glutathione metabolism in the substantia nigra of patients. Neurosci Lett 1986 1.17
20 Microglial production of TNF-alpha is induced by activated T lymphocytes. Involvement of VLA-4 and inhibition by interferonbeta-1b. J Clin Invest 1997 1.15
21 Interleukin-1 beta is required for the early evolution of reactive astrogliosis following CNS lesion. J Neuropathol Exp Neurol 2001 1.15
22 Involvement of p21(Waf1/Cip1) in protein kinase C alpha-induced cell cycle progression. Mol Cell Biol 2000 1.13
23 Differential activation of ERKs to focal adhesions by PKC epsilon is required for PMA-induced adhesion and migration of human glioma cells. Oncogene 2001 1.12
24 HIV-1 Tat neurotoxicity is prevented by matrix metalloproteinase inhibitors. Ann Neurol 2001 1.04
25 Oligodendrocytes utilize a matrix metalloproteinase, MMP-9, to extend processes along an astrocyte extracellular matrix. Glia 1998 1.03
26 Marked inhibition of tumor growth in a malignant glioma tumor model by a novel synthetic matrix metalloproteinase inhibitor AG3340. Clin Cancer Res 1999 1.03
27 Astrocytes attenuate oligodendrocyte death in vitro through an alpha(6) integrin-laminin-dependent mechanism. Glia 2001 1.01
28 Amino acids, glutathione, and glutathione transferase activity in the brains of patients with Alzheimer's disease. Ann Neurol 1987 1.01
29 Glatiramer acetate in combination with minocycline in patients with relapsing--remitting multiple sclerosis: results of a Canadian, multicenter, double-blind, placebo-controlled trial. Mult Scler 2009 1.01
30 Glioma invasion in vitro: regulation by matrix metalloprotease-2 and protein kinase C. Clin Exp Metastasis 1996 1.00
31 Attenuation of astroglial reactivity by interleukin-10. J Neurosci 1996 0.98
32 Enhanced protein kinase C activity correlates with the growth rate of malignant gliomas in vitro. Neurosurgery 1991 0.97
33 Mechanisms of IL-10 production in human microglia-T cell interaction. J Immunol 1999 0.96
34 Infection of primary cultures of human neural cells by human coronaviruses 229E and OC43. J Virol 1997 0.95
35 Chemokine-enhanced migration of human peripheral blood mononuclear cells is antagonized by interferon beta-1b through an effect on matrix metalloproteinase-9. J Neuroimmunol 1997 0.95
36 Astrogliosis in the neonatal and adult murine brain post-trauma: elevation of inflammatory cytokines and the lack of requirement for endogenous interferon-gamma. J Neurosci 1997 0.94
37 Mechanisms of glioma invasion: role of matrix-metalloproteinases. Can J Neurol Sci 1997 0.92
38 Protein kinase C activity correlates with the growth rate of malignant gliomas: Part II. Effects of glioma mitogens and modulators of protein kinase C. Neurosurgery 1992 0.90
39 Interferon beta-1b increases interleukin-10 in a model of T cell-microglia interaction: relevance to MS. Neurology 2000 0.90
40 Partial protection from the dopaminergic neurotoxin N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine by four different antioxidants in the mouse. Neurosci Lett 1985 0.90
41 Interferon-beta is a potent promoter of nerve growth factor production by astrocytes. J Neurochem 1997 0.89
42 Induction of RANTES expression by astrocytes and astrocytoma cell lines. J Neuroimmunol 1996 0.89
43 Mitogenic signaling and the relationship to cell cycle regulation in astrocytomas. J Neurooncol 2001 0.88
44 Origin of contralateral reactive gliosis in surgically injured rat cerebral cortex. Brain Res 1991 0.87
45 Astrocyte reactivity in neonatal mice: apparent dependence on the presence of reactive microglia/macrophages. Glia 1996 0.86
46 Antigen presentation by human fetal astrocytes with the cooperative effect of microglia or the microglial-derived cytokine IL-1. J Neurosci 1995 0.84
47 Protein kinase C and growth regulation of malignant gliomas. Can J Neurol Sci 1995 0.83
48 Migratory behavior of lymphocytes isolated from multiple sclerosis patients: effects of interferon beta-1b therapy. Ann Neurol 1999 0.83
49 Cytokine production in T lymphocyte-microglia interaction is attenuated by glatiramer acetate: a mechanism for therapeutic efficacy in multiple sclerosis. Mult Scler 2002 0.83
50 Nigrostriatal dopaminergic neurons remain undamaged in rats given high doses of L-DOPA and carbidopa chronically. J Neurochem 1984 0.83
51 Signal transduction for proliferation of glioma cells in vitro occurs predominantly through a protein kinase C-mediated pathway. Brain Res 1996 0.83
52 Protein kinase C inhibitors suppress cell growth in established and low-passage glioma cell lines. A comparison between staurosporine and tamoxifen. Neurosurgery 1993 0.82
53 Cytokine production consequent to T cell--microglia interaction: the PMA/IFN gamma-treated U937 cells display similarities to human microglia. J Neurosci Methods 2001 0.82
54 Alpha-tocopherol and beta-carotene do not protect marmosets against the dopaminergic neurotoxicity of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. J Neurol Sci 1987 0.82
55 Adenovirus-mediated wild-type p53 gene transfer and overexpression induces apoptosis of human glioma cells independent of endogenous p53 status. J Neuropathol Exp Neurol 1997 0.82
56 Astrocytes promote process outgrowth by adult human oligodendrocytes in vitro through interaction between bFGF and astrocyte extracellular matrix. Glia 1996 0.82
57 Astrocytes and catalase prevent the toxicity of catecholamines to oligodendrocytes. Brain Res 1994 0.81
58 Monoamine oxidase B, smoking, and Parkinson's disease. J Neurol Sci 1986 0.81
59 Asymptomatic striatal dopamine depletion: PET scans in unilateral MPTP monkeys. Synapse 1988 0.81
60 Staurosporine differentially inhibits glioma versus non-glioma cell lines. J Neurooncol 1993 0.80
61 Immune-mediated neurodegeneration and neuroprotection in MS. Int MS J 2003 0.80
62 Production of soluble autocrine inhibitory factors by human glioma cell lines. J Neurol Sci 1992 0.79
63 Oligodendrocytes and myelin. Neurol Clin 1995 0.79
64 The promoting effects of bFGF and astrocyte extracellular matrix on process outgrowth by adult human oligodendrocytes are mediated by protein kinase C. Brain Res 1997 0.79
65 Paraquat and two endogenous analogues of the neurotoxic substance N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine do not damage dopaminergic nigrostriatal neurons in the mouse. Neurosci Lett 1986 0.79
66 Depletion of glutathione in brainstem of mice caused by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine is prevented by antioxidant pretreatment. Neurosci Lett 1986 0.79
67 Immune and non-immune actions of interferon-beta-Ib on primary human neural cells. Mult Scler 1995 0.78
68 3T deep gray matter T2 hypointensity correlates with disability over time in stable relapsing-remitting multiple sclerosis: a 3-year pilot study. J Neurol Sci 2010 0.78
69 Effects of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and its metabolite, N-methyl-4-phenylpyridinium ion, on dopaminergic nigrostriatal neurons in the mouse. Neurosci Lett 1985 0.78
70 TGF-B2 and soluble p55 TNFR modulate VCAM-1 expression in glioma cells and brain derived endothelial cells. J Neuroimmunol 1997 0.78
71 The astrocyte mitogen, tumor necrosis factor-alpha, inhibits the proliferative effect of more potent adult human astrocyte mitogens, gamma-interferon and activated T-lymphocyte supernatants. Brain Res 1994 0.78
72 The failure of morphine to depress selectively non-adrenergic neural inhibition of the guinea-pig taenia caeci. J Pharm Pharmacol 1983 0.77
73 Microglial reaction in some CNS nuclei following nerves transection in BALB/c and interferon-gamma gene knockout mice. Neurosci Lett 1999 0.77
74 Protein kinase C and growth regulation of pituitary adenomas. Acta Neurochir Suppl 1996 0.77
75 Manipulation of glutathione contents fails to alter dopaminergic nigrostriatal neurotoxicity of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the mouse. Neurosci Lett 1986 0.77
76 alpha2,3-sialyltransferase mRNA and alpha2,3-linked glycoprotein sialylation are increased in malignant gliomas. Brain Res 1997 0.77
77 Protein kinase C activity and intracellular distribution in surgically excised human epileptic neocortex. Brain Res 1991 0.76
78 Malignant glioma-derived soluble factors regulate proliferation of normal adult human astrocytes. J Neuropathol Exp Neurol 1992 0.76
79 Apoptosis is induced in glioma cells by antisense oligonucleotides to protein kinase C alpha and is enhanced by cycloheximide. Neuroreport 1998 0.76
80 Differential role for protein kinase C-mediated signaling in the proliferation of medulloblastoma cell lines. Int J Oncol 1998 0.76
81 The therapeutic potential of chemokine-toxin fusion proteins. IDrugs 2001 0.76
82 Neurochemical abnormalities in brains of renal failure patients treated by repeated hemodialysis. J Neurochem 1985 0.76
83 Protein kinase C isoform alpha overexpression in C6 glioma cells and its role in cell proliferation. J Neurooncol 1995 0.76
84 Human fetal Schwann cells in culture: phenotypic expressions and proliferative capability. J Neurosci Res 1989 0.75
85 Chronic organic manganese administration in the rat does not damage dopaminergic nigrostriatal neurons. Neurotoxicology 1986 0.75
86 Glioma invasion. J Neurosurg 2001 0.75
87 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) does not destroy nigrostriatal neurons in the scorbutic guinea pig. Life Sci 1985 0.75
88 Tissue culture evidence for a circulating neurotoxin in Huntington's chorea. J Neurol Sci 1987 0.75
89 Chronic treatment with ACTH1-24 does not produce permanent damage to the developing rat brain. Brain Res 1985 0.75
90 Identification of GTP-binding proteins in myelin and oligodendrocyte membranes. J Neurosci Res 1990 0.75
91 Is a circulating neurotoxin involved in the pathogenesis of Huntington's chorea? J Neurol Sci 1985 0.75
92 Inability to produce a model of dialysis encephalopathy in the rat by aluminum administration. Neurochem Res 1987 0.75