Epigenetic epidemiology of the developmental origins hypothesis.

Persistent epigenetic differences associated with prenatal exposure to famine in humans. Proc Natl Acad Sci U S A (2008) 8.39

DNA methylation differences after exposure to prenatal famine are common and timing- and sex-specific. Hum Mol Genet (2009) 4.25

Ten putative contributors to the obesity epidemic. Crit Rev Food Sci Nutr (2009) 2.71

Season of conception in rural gambia affects DNA methylation at putative human metastable epialleles. PLoS Genet (2010) 2.49

ATF4-dependent transcription mediates signaling of amino acid limitation. Trends Endocrinol Metab (2009) 2.49

Mapping DNA methylation across development, genotype and schizophrenia in the human frontal cortex. Nat Neurosci (2015) 2.31

The impact of perinatal immune development on mucosal homeostasis and chronic inflammation. Nat Rev Immunol (2011) 2.29

Child health, developmental plasticity, and epigenetic programming. Endocr Rev (2010) 2.15

Developmental origins of health and disease: brief history of the approach and current focus on epigenetic mechanisms. Semin Reprod Med (2009) 2.03

Maternal diet and aging alter the epigenetic control of a promoter-enhancer interaction at the Hnf4a gene in rat pancreatic islets. Proc Natl Acad Sci U S A (2011) 1.95

The environment and susceptibility to schizophrenia. Prog Neurobiol (2010) 1.94

DNA methylation potential: dietary intake and blood concentrations of one-carbon metabolites and cofactors in rural African women. Am J Clin Nutr (2013) 1.88

Canaries in the coal mine: a cross-species analysis of the plurality of obesity epidemics. Proc Biol Sci (2010) 1.86

From promises to practical strategies in epigenetic epidemiology. Nat Rev Genet (2013) 1.82

Maternal nutrition at conception modulates DNA methylation of human metastable epialleles. Nat Commun (2014) 1.73

Epigenetics and cardiovascular disease. Nat Rev Cardiol (2010) 1.68

Prenatal famine and adult health. Annu Rev Public Health (2011) 1.67

Prenatal exposure to maternal smoking and offspring DNA methylation across the lifecourse: findings from the Avon Longitudinal Study of Parents and Children (ALSPAC). Hum Mol Genet (2014) 1.58

Early origins of inflammation: microbial exposures in infancy predict lower levels of C-reactive protein in adulthood. Proc Biol Sci (2009) 1.51

Perinatal complications and aging indicators by midlife. Pediatrics (2014) 1.51

Sex differences in the developmental origins of hypertension and cardiorenal disease. Am J Physiol Regul Integr Comp Physiol (2008) 1.48

Prenatal arsenic exposure and DNA methylation in maternal and umbilical cord blood leukocytes. Environ Health Perspect (2012) 1.47

Effect of antenatal multiple micronutrient supplementation on anthropometry and blood pressure in mid-childhood in Nepal: follow-up of a double-blind randomised controlled trial. Lancet Glob Health (2014) 1.47

Developmental origins of health and disease: environmental exposures. Semin Reprod Med (2009) 1.44

Birthweight, maternal weight trajectories and global DNA methylation of LINE-1 repetitive elements. PLoS One (2011) 1.41

Breastfeeding effects on DNA methylation in the offspring: A systematic literature review. PLoS One (2017) 1.38

Epigenetics, epidemiology and mitochondrial DNA diseases. Int J Epidemiol (2012) 1.36

Identification of DNA methylation changes in newborns related to maternal smoking during pregnancy. Environ Health Perspect (2014) 1.35

Methylation quantitative trait loci (meQTLs) are consistently detected across ancestry, developmental stage, and tissue type. BMC Genomics (2014) 1.34

Physical activity and global genomic DNA methylation in a cancer-free population. Epigenetics (2011) 1.32

DNA methylation signatures link prenatal famine exposure to growth and metabolism. Nat Commun (2014) 1.28

Developmental periods of choline sensitivity provide an ontogenetic mechanism for regulating memory capacity and age-related dementia. Front Integr Neurosci (2008) 1.26

Maternal methyl-donor supplementation induces prolonged murine offspring colitis susceptibility in association with mucosal epigenetic and microbiomic changes. Hum Mol Genet (2011) 1.26

Maternal nutritional status, C(1) metabolism and offspring DNA methylation: a review of current evidence in human subjects. Proc Nutr Soc (2011) 1.25

Prenatal famine and genetic variation are independently and additively associated with DNA methylation at regulatory loci within IGF2/H19. PLoS One (2012) 1.24

Genome-wide peripheral blood leukocyte DNA methylation microarrays identified a single association with inflammatory bowel diseases. Inflamm Bowel Dis (2012) 1.22

Early life exposure to famine and colorectal cancer risk: a role for epigenetic mechanisms. PLoS One (2009) 1.21

Perinatal programming of asthma: the role of gut microbiota. Clin Dev Immunol (2011) 1.21

Early life nutrition, epigenetics and programming of later life disease. Nutrients (2014) 1.18

Postnatal stability, tissue, and time specific effects of AHRR methylation change in response to maternal smoking in pregnancy. Epigenetics (2013) 1.17

Dietary patterns are associated with levels of global genomic DNA methylation in a cancer-free population. J Nutr (2011) 1.17

Is epidemiology ready for epigenetics? Int J Epidemiol (2012) 1.17

Expression profiling after activation of amino acid deprivation response in HepG2 human hepatoma cells. Physiol Genomics (2010) 1.15

Genetics and epigenetics of obesity. Maturitas (2011) 1.14

Gestational intake of methyl donors and global LINE-1 DNA methylation in maternal and cord blood: prospective results from a folate-replete population. Epigenetics (2012) 1.10

Genes and elite athletes: a roadmap for future research. J Physiol (2011) 1.10

Environmental epigenetics and its implication on disease risk and health outcomes. ILAR J (2012) 1.10

The emerging role of epigenetic mechanisms in the etiology of neural tube defects. Epigenetics (2011) 1.08

Is there an optimum endurance polygenic profile? J Physiol (2009) 1.08

DNA methylation, an epigenetic mechanism connecting folate to healthy embryonic development and aging. J Nutr Biochem (2009) 1.06

Complex genetics of obesity in mouse models. Annu Rev Nutr (2008) 1.06

Global DNA methylation levels in girls with and without a family history of breast cancer. Epigenetics (2011) 1.06

Epigenetic maturation in colonic mucosa continues beyond infancy in mice. Hum Mol Genet (2010) 1.06

A classification of sociomedical health indicators: perspectives for health administrators and health planners. Int J Health Serv (1976) 1.04

Physiological adaptations to weight loss and factors favouring weight regain. Int J Obes (Lond) (2015) 1.04

A strategy for analyzing gene-nutrient interactions in type 2 diabetes. J Diabetes Sci Technol (2009) 1.03

Patterning in placental 11-B hydroxysteroid dehydrogenase methylation according to prenatal socioeconomic adversity. PLoS One (2013) 1.03

Early environments and the ecology of inflammation. Proc Natl Acad Sci U S A (2012) 1.03

Epigenomics in environmental health. Front Genet (2011) 1.02

Parent-of-origin effects on voluntary exercise levels and body composition in mice. Physiol Genomics (2009) 1.02

Arsenic exposure in early pregnancy alters genome-wide DNA methylation in cord blood, particularly in boys. J Dev Orig Health Dis (2014) 1.01

Imprint regulatory elements as epigenetic biosensors of exposure in epidemiological studies. J Epidemiol Community Health (2009) 1.01

A common cause for a common phenotype: the gatekeeper hypothesis in fetal programming. Med Hypotheses (2011) 1.01

The role of longitudinal cohort studies in epigenetic epidemiology: challenges and opportunities. Genome Biol (2012) 1.00

The effects of depression and use of antidepressive medicines during pregnancy on the methylation status of the IGF2 imprinted control regions in the offspring. Clin Epigenetics (2011) 1.00

Associations of gestational exposure to famine with energy balance and macronutrient density of the diet at age 58 years differ according to the reference population used. J Nutr (2009) 1.00

Independent genomewide screens identify the tumor suppressor VTRNA2-1 as a human epiallele responsive to periconceptional environment. Genome Biol (2015) 0.99

Early-life origins of type 2 diabetes: fetal programming of the beta-cell mass. Exp Diabetes Res (2011) 0.98

Beyond the fourth wave of genome-wide obesity association studies. Nutr Diabetes (2012) 0.98

Environmental chemicals and DNA methylation in adults: a systematic review of the epidemiologic evidence. Clin Epigenetics (2015) 0.98

Epigenetics and the developmental origins of inflammatory bowel diseases. Can J Gastroenterol (2012) 0.97

Epigenetic effects of human breast milk. Nutrients (2014) 0.96

Epigenetics in adipose tissue, obesity, weight loss, and diabetes. Adv Nutr (2014) 0.96

Epigenome: biosensor of cumulative exposure to chemical and nonchemical stressors related to environmental justice. Am J Public Health (2014) 0.95

DNA methylation at imprint regulatory regions in preterm birth and infection. Am J Obstet Gynecol (2013) 0.95

Approaches for drawing causal inferences from epidemiological birth cohorts: a review. Early Hum Dev (2014) 0.95

Characterization of the elemental composition of newborn blood spots using sector-field inductively coupled plasma-mass spectrometry. J Expo Sci Environ Epidemiol (2010) 0.94

Perinatal and family risk factors for Hodgkin lymphoma in childhood through young adulthood. Am J Epidemiol (2012) 0.94

Predictors and consequences of global DNA methylation in cord blood and at three years. PLoS One (2013) 0.94

Epigenetics: deciphering how environmental factors may modify autoimmune type 1 diabetes. Mamm Genome (2009) 0.92

Maternal antenatal multiple micronutrient supplementation for long-term health benefits in children: a systematic review and meta-analysis. BMC Med (2016) 0.92

Maternal stress, preterm birth, and DNA methylation at imprint regulatory sequences in humans. Genet Epigenet (2014) 0.91

Maternal choline modifies fetal liver copper, gene expression, DNA methylation, and neonatal growth in the tx-j mouse model of Wilson disease. Epigenetics (2013) 0.91

Late insights into early origins of disease. Basic Clin Pharmacol Toxicol (2008) 0.91

DNA methylation in gastric cancer, related to Helicobacter pylori and Epstein-Barr virus. World J Gastroenterol (2014) 0.91

Early influences on cardiovascular and renal development. Eur J Epidemiol (2010) 0.90

Early onset pre-eclampsia is associated with altered DNA methylation of cortisol-signalling and steroidogenic genes in the placenta. PLoS One (2013) 0.90

Immune responses accelerate ageing: proof-of-principle in an insect model. PLoS One (2011) 0.90

Early life socioeconomic factors and genomic DNA methylation in mid-life. Epigenetics (2012) 0.89

Maternal obesity and gestational diabetes are associated with placental leptin DNA methylation. Am J Obstet Gynecol (2014) 0.89

Early postnatal nutrition determines adult physical activity and energy expenditure in female mice. Diabetes (2013) 0.89

Early life precursors, epigenetics, and the development of food allergy. Semin Immunopathol (2012) 0.89

From Mice to Men: research models of developmental programming. J Dev Orig Health Dis (2013) 0.89

DISC1 mouse models as a tool to decipher gene-environment interactions in psychiatric disorders. Front Behav Neurosci (2013) 0.88

Early life nutritional programming of health and disease in The Gambia. J Dev Orig Health Dis (2015) 0.88

Recreational and household physical activity at different time points and DNA global methylation. Eur J Cancer (2013) 0.88

Vitamin B(12) intake and status in early pregnancy among urban South Indian women. Ann Nutr Metab (2013) 0.86

Genetics talks to epigenetics? The interplay between sequence variants and chromatin structure. Curr Genomics (2010) 0.86

A methyl-deficient diet fed to rat dams during the peri-conception period programs glucose homeostasis in adult male but not female offspring. J Nutr (2010) 0.86

Early gestation as the critical time-window for changes in the prenatal environment to affect the adult human blood methylome. Int J Epidemiol (2015) 0.86

Observational studies analyzed like randomized experiments: an application to postmenopausal hormone therapy and coronary heart disease. Epidemiology (2008) 6.87

Use of antidepressants near delivery and risk of postpartum hemorrhage: cohort study of low income women in the United States. BMJ (2013) 3.88

Diabetes, metabolic syndrome, and breast cancer: a review of the current evidence. Am J Clin Nutr (2007) 3.27

Duration of lactation and incidence of type 2 diabetes. JAMA (2005) 2.84

Polycarbonate bottle use and urinary bisphenol A concentrations. Environ Health Perspect (2009) 2.72

Intrauterine factors and risk of breast cancer: a systematic review and meta-analysis of current evidence. Lancet Oncol (2007) 2.34

Birth weight and the risk of testicular cancer: a meta-analysis. Int J Cancer (2007) 2.19

Consumption of low-fat dairy products may delay natural menopause. J Nutr (2013) 2.04

A prospective study of breast size and premenopausal breast cancer incidence. Int J Cancer (2006) 2.04

Urinary bisphenol A and obesity: NHANES 2003-2006. Environ Res (2011) 2.02

Measurement error correction for nutritional exposures with correlated measurement error: use of the method of triads in a longitudinal setting. Stat Med (2008) 2.01

Cigarette smoking and the incidence of breast cancer. Arch Intern Med (2011) 1.97

Longitudinal study of birth weight and adult body mass index in predicting risk of coronary heart disease and stroke in women. BMJ (2005) 1.90

Green tea consumption and breast cancer risk or recurrence: a meta-analysis. Breast Cancer Res Treat (2009) 1.86

Gestational vitamin D and the risk of multiple sclerosis in offspring. Ann Neurol (2011) 1.85

Prenatal and perinatal factors and risk of multiple sclerosis. Epidemiology (2009) 1.80

Body fatness during childhood and adolescence and incidence of breast cancer in premenopausal women: a prospective cohort study. Breast Cancer Res (2005) 1.77

Harnessing the Medicaid Analytic eXtract (MAX) to Evaluate Medications in Pregnancy: Design Considerations. PLoS One (2013) 1.74

A prospective study on habitual duration of sleep and incidence of breast cancer in a large cohort of women. Cancer Res (2006) 1.68

Adult recall of adolescent diet: reproducibility and comparison with maternal reporting. Am J Epidemiol (2005) 1.62

Birthweight and body size throughout life in relation to sex hormones and prolactin concentrations in premenopausal women. Cancer Epidemiol Biomarkers Prev (2006) 1.57

Duration of lactation and incidence of myocardial infarction in middle to late adulthood. Am J Obstet Gynecol (2008) 1.55

Canned soup consumption and urinary bisphenol A: a randomized crossover trial. JAMA (2011) 1.47

In utero exposures and the incidence of endometriosis. Fertil Steril (2004) 1.41

Birth weight and childhood leukemia: a meta-analysis and review of the current evidence. Int J Cancer (2009) 1.38

Body size across the life course, mammographic density, and risk of breast cancer. Am J Epidemiol (2011) 1.28

Lactation and incidence of premenopausal breast cancer: a longitudinal study. Arch Intern Med (2009) 1.23

Dads as breastfeeding advocates: results from a randomized controlled trial of an educational intervention. Am J Obstet Gynecol (2004) 1.20

Exposure to cigarette smoke in utero: comparison of reports from mother and daughter. Epidemiology (2008) 1.11

Estimating treatment effects from observational data: dissonant and resonant notes from the SYMPHONY trials. JAMA (2002) 1.09

Duration of lactation and incidence of maternal hypertension: a longitudinal cohort study. Am J Epidemiol (2011) 1.08

Menstrual cycle characteristics and incidence of premenopausal breast cancer. Cancer Epidemiol Biomarkers Prev (2005) 1.08

Defibulation to treat female genital cutting: effect on symptoms and sexual function. Obstet Gynecol (2006) 1.06

Postpartum remodeling, lactation, and breast cancer risk: summary of a National Cancer Institute-sponsored workshop. J Natl Cancer Inst (2012) 1.02

Environmental pollutants, diet, physical activity, body size, and breast cancer: where do we stand in research to identify opportunities for prevention? Cancer (2007) 1.02

Plasma leptin levels and risk of breast cancer in premenopausal women. Cancer Prev Res (Phila) (2011) 1.00

Body fat distribution and risk of premenopausal breast cancer in the Nurses' Health Study II. J Natl Cancer Inst (2010) 0.99

Smoking and other lifestyle factors and the risk of Graves' hyperthyroidism. Arch Intern Med (2005) 0.98

Anthropometric and hormonal risk factors for male breast cancer: male breast cancer pooling project results. J Natl Cancer Inst (2014) 0.98

A prospective study of infertility due to ovulatory disorders, ovulation induction, and incidence of breast cancer. Arch Intern Med (2006) 0.97

Breast cancer--early life matters. N Engl J Med (2004) 0.95

Validity of adolescent diet recall 48 years later. Am J Epidemiol (2009) 0.95

Postmenopausal hormone therapy: a reversal of fortune. Circulation (2003) 0.95

Antidepressant use and risk for preeclampsia. Epidemiology (2013) 0.95

Chromatin fluorescence characteristics and standard semen analysis parameters: correlations observed in andrology testing among 136 males referred for infertility evaluation. J Obstet Gynaecol (2004) 0.93

Parental characteristics as predictors of birthweight. Hum Reprod (2007) 0.92

Adult height, age at attained height, and incidence of breast cancer in premenopausal women. Int J Cancer (2006) 0.92

Caffeine consumption during pregnancy and risk of preterm birth: a meta-analysis. Am J Clin Nutr (2010) 0.92

Shall we put the world on folate? Lancet (2009) 0.92

Childhood abuse and age at menarche. J Adolesc Health (2012) 0.91

The role of folic acid fortification in neural tube defects: a review. Crit Rev Food Sci Nutr (2013) 0.91

Breastfeeding during infancy and the risk of cardiovascular disease in adulthood. Epidemiology (2004) 0.90

Nutritional epidemiology--past, present, future. Int J Epidemiol (2003) 0.90

Antihypertensive medication use and incident breast cancer in women. Breast Cancer Res Treat (2015) 0.89

Breast size and risk of type 2 diabetes mellitus. CMAJ (2008) 0.88

Maternal pregnancy-related hypertension and risk for hypertension in offspring later in life. Obstet Gynecol (2010) 0.88

Validity of maternal recall of preschool diet after 43 years. Am J Epidemiol (2009) 0.88

Leukocyte DNA as surrogate for the evaluation of imprinted Loci methylation in mammary tissue DNA. PLoS One (2013) 0.87

Parental age at delivery and incidence of breast cancer: a prospective cohort study. Breast Cancer Res Treat (2006) 0.86

The causal effect of red blood cell folate on genome-wide methylation in cord blood: a Mendelian randomization approach. BMC Bioinformatics (2013) 0.84

First-Trimester Urine Concentrations of Phthalate Metabolites and Phenols and Placenta miRNA Expression in a Cohort of U.S. Women. Environ Health Perspect (2015) 0.83

The prevalence of loss of imprinting of H19 and IGF2 at birth. FASEB J (2013) 0.82

Economic factors and the percentage of residency positions filled by United States medical graduates. Obstet Gynecol (2005) 0.82

A cervical abnormality risk prediction model: can we use clinical information to predict which patients with ASCUS/LSIL Pap tests will develop CIN 2/3 or AIS? J Low Genit Tract Dis (2013) 0.82

Leptin and leptin receptor genes in relation to premenopausal breast cancer incidence and grade in Caucasian women. Breast Cancer Res Treat (2011) 0.82

Mothers' pre-pregnancy BMI and weight gain during pregnancy and risk of breast cancer in daughters. Breast Cancer Res Treat (2011) 0.80

Gestational weight gain and daughter's age at menarche. J Womens Health (Larchmt) (2011) 0.80

The women's health initiative--curse or blessing? Int J Epidemiol (2006) 0.78

Parental smoking in pregnancy and the risks of adult-onset hypertension. Hypertension (2012) 0.78

Physical activity during pregnancy and age at menarche of the daughter. Cancer Epidemiol Biomarkers Prev (2008) 0.78

Risk of breast cancer among daughters of mothers with diabetes: a population-based cohort study. Breast Cancer Res (2010) 0.78

Infant feeding and the incidence of endometrial cancer. Cancer Epidemiol Biomarkers Prev (2008) 0.77

Evaluation of a questionnaire to assess selected infectious diseases and their risk factors : findings of a multicenter study. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz (2014) 0.77

A maternalistic approach to prevention. Int J Epidemiol (2005) 0.76

The rise and fall of breast cancer rates. BMJ (2012) 0.75

Reply to Desai and Gillett-Heacock. J Nutr (2014) 0.75

The promise and challenges of population strategies of prevention. Int J Epidemiol (2008) 0.75

Maternal and Early Childhood Determinants of Women's Body Size in Midlife: Overall Cohort and Sibling Analyses. Am J Epidemiol (2017) 0.75

Prepubertal exposure to cow's milk reduces susceptibility to carcinogen-induced mammary tumorigenesis in rats. Int J Cancer (2011) 0.75

The education corner: updates on new and established core concepts and methods in epidemiology. Int J Epidemiol (2012) 0.75

Increase in Mental Disorders During the COVID-19 Pandemic-the Role of Occupational and Financial Strains. An Analysis of the German National Cohort (NAKO) Study. Dtsch Arztebl Int (2022) 0.75

Cesarean section and placental disorders in subsequent pregnancies--a meta-analysis. J Perinat Med (2014) 0.75