Hyperthermia: a potent enhancer of radiotherapy.

PubWeight™: 2.07‹?› | Rank: Top 2%

🔗 View Article (PMID 17493790)

Published in Clin Oncol (R Coll Radiol) on May 10, 2007

Authors

M R Horsman1, J Overgaard

Author Affiliations

1: Department of Experimental Clinical Oncology, Aarhus University Hospital, Aarhus, Denmark. mike@oncology.dk

Articles citing this

Gold nanorod assisted near-infrared plasmonic photothermal therapy (PPTT) of squamous cell carcinoma in mice. Cancer Lett (2008) 3.20

Novel substituted (Z)-2-(N-benzylindol-3-ylmethylene)quinuclidin-3-one and (Z)-(+/-)-2-(N-benzylindol-3-ylmethylene)quinuclidin-3-ol derivatives as potent thermal sensitizing agents. Bioorg Med Chem Lett (2007) 3.14

Imaging hypoxia to improve radiotherapy outcome. Nat Rev Clin Oncol (2012) 1.57

Magnetic nanoparticles with high specific absorption rate of electromagnetic energy at low field strength for hyperthermia therapy. J Appl Phys (2015) 1.46

Thermal enhancement with optically activated gold nanoshells sensitizes breast cancer stem cells to radiation therapy. Sci Transl Med (2010) 1.43

MAGNETIC NANOPARTICLE HYPERTHERMIA IN CANCER TREATMENT. Nano Life (2010) 1.41

Magnetic nanoparticle biodistribution following intratumoral administration. Nanotechnology (2011) 1.32

Novel substituted (Z)-5-((N-benzyl-1H-indol-3-yl)methylene)imidazolidine-2,4-diones and 5-((N-benzyl-1H-indol-3-yl)methylene)pyrimidine-2,4,6(1H,3H,5H)-triones as potent radio-sensitizing agents. Bioorg Med Chem Lett (2009) 1.19

CEM43°C thermal dose thresholds: a potential guide for magnetic resonance radiofrequency exposure levels? Eur Radiol (2013) 1.15

Comparison of genomics and functional imaging from canine sarcomas treated with thermoradiotherapy predicts therapeutic response and identifies combination therapeutics. Clin Cancer Res (2011) 0.94

Increased radiosensitivity and radiothermosensitivity of human pancreatic MIA PaCa-2 and U251 glioblastoma cell lines treated with the novel Hsp90 inhibitor NVP-HSP990. Radiat Oncol (2013) 0.88

Effects of hyperthermia on DNA repair pathways: one treatment to inhibit them all. Radiat Oncol (2015) 0.88

Preliminary study of injury from heating systemically delivered, nontargeted dextran-superparamagnetic iron oxide nanoparticles in mice. Nanomedicine (Lond) (2012) 0.87

The impact of hypoxia and its modification of the outcome of radiotherapy. J Radiat Res (2016) 0.86

Hyperthermia inhibits platelet hemostatic functions and selectively regulates the release of alpha-granule proteins. J Thromb Haemost (2011) 0.85

Risks and safety aspects related to PET/MR examinations. Eur J Nucl Med Mol Imaging (2009) 0.85

Time and dose dependence of pluronic bioactivity in hyperthermia-induced tumor cell death. Exp Biol Med (Maywood) (2008) 0.85

Combination of ionising irradiation and hyperthermia activates programmed apoptotic and necrotic cell death pathways in human colorectal carcinoma cells. Strahlenther Onkol (2010) 0.84

Hyperthermia inhibits hypoxia-induced epithelial-mesenchymal transition in HepG2 hepatocellular carcinoma cells. World J Gastroenterol (2012) 0.84

Clinical oxygen enhancement ratio of tumors in carbon ion radiotherapy: the influence of local oxygenation changes. J Radiat Res (2014) 0.84

Hyperthermia as adjunct to intravesical chemotherapy for bladder cancer. Biomed Res Int (2013) 0.84

Thermal boost combined with interstitial brachytherapy in breast conserving therapy - Assessment of early toxicity. Rep Pract Oncol Radiother (2011) 0.84

Convergence of nanotechnology with radiation therapy-insights and implications for clinical translation. Transl Cancer Res (2013) 0.82

Gold nanoparticle hyperthermia reduces radiotherapy dose. Nanomedicine (2014) 0.81

Rad9, Rad17, TopBP1 and claspin play essential roles in heat-induced activation of ATR kinase and heat tolerance. PLoS One (2013) 0.81

Magnetic nanoparticle hyperthermia: Predictive model for temperature distribution. Proc SPIE Int Soc Opt Eng (2013) 0.81

Modulation of the tumor vasculature and oxygenation to improve therapy. Pharmacol Ther (2015) 0.80

Understanding mNP Hyperthermia for cancer treatment at the cellular scale. Proc SPIE Int Soc Opt Eng (2013) 0.79

Method to reduce non-specific tissue heating of small animals in solenoid coils. Int J Hyperthermia (2013) 0.79

Feasibility of concurrent treatment with the scanning ultrasound reflector linear array system (SURLAS) and the helical tomotherapy system. Int J Hyperthermia (2008) 0.79

Hyperthermia Sensitizes Glioma Stem-like Cells to Radiation by Inhibiting AKT Signaling. Cancer Res (2015) 0.79

Single agent nanoparticle for radiotherapy and radio-photothermal therapy in anaplastic thyroid cancer. Biomaterials (2015) 0.78

Magnetic nanoparticles and nanocomposites for remote controlled therapies. J Control Release (2015) 0.78

Local hyperthermia in head and neck cancer: mechanism, application and advance. Oncotarget (2016) 0.77

Localized hyperthermia with iron oxide-doped yttrium microparticles: steps toward image-guided thermoradiotherapy in liver cancer. J Vasc Interv Radiol (2013) 0.77

Nucleophosmin redistribution following heat shock: a role in heat-induced radiosensitization. Cancer Res (2009) 0.77

Magnetic nanoparticle hyperthermia enhances radiation therapy: A study in mouse models of human prostate cancer. Int J Hyperthermia (2015) 0.77

Biological modelling of the radiation dose escalation effect of regional hyperthermia in cervical cancer. Radiat Oncol (2016) 0.77

In vivo verification of regional hyperthermia in the liver. Radiat Oncol J (2014) 0.77

Photo-thermal effect enhances the efficiency of radiotherapy using Arg-Gly-Asp peptides-conjugated gold nanorods that target αvβ3 in melanoma cancer cells. J Nanobiotechnology (2015) 0.77

The in vitro immunogenic potential of caspase-3 proficient breast cancer cells with basal low immunogenicity is increased by hypofractionated irradiation. Radiat Oncol (2015) 0.76

Status quo and directions in deep head and neck hyperthermia. Radiat Oncol (2016) 0.76

Hyperthermia: How Can It Be Used? Oman Med J (2016) 0.76

Oxygen microenvironment affects the uptake of nanoparticles in head and neck tumor cells. Proc SPIE Int Soc Opt Eng (2013) 0.75

Review: the role of hyperthermia in treating pancreatic tumors. Indian J Surg Oncol (2014) 0.75

A genomics approach to identify susceptibilities of breast cancer cells to "fever-range" hyperthermia. BMC Cancer (2014) 0.75

High-intensity focused ultrasound plus concomitant radiotherapy: a new weapon in oncology? J Ther Ultrasound (2013) 0.75

Molecular Imaging-Guided Interventional Hyperthermia in Treatment of Breast Cancer. Biomed Res Int (2015) 0.75

Mitigation of eddy current heating during magnetic nanoparticle hyperthermia therapy. Int J Hyperthermia (2016) 0.75

Magnetic resonance-guided high-intensity focused ultrasound combined with radiotherapy for palliation of head and neck cancer-a pilot study. J Ther Ultrasound (2016) 0.75

A short time interval between radiotherapy and hyperthermia reduces in-field recurrence and mortality in women with advanced cervical cancer. Radiat Oncol (2017) 0.75

Experimental estimation and analysis of variance of the measured loss power of magnetic nanoparticles. Sci Rep (2017) 0.75

New experimental model for single liver lobe hyperthermia in small animals using non-directional microwaves. PLoS One (2017) 0.75

Harnessing the Power of Nanotechnology for Enhanced Radiation Therapy. ACS Nano (2017) 0.75

Articles by these authors

(truncated to the top 100)

Postoperative radiotherapy in high-risk premenopausal women with breast cancer who receive adjuvant chemotherapy. Danish Breast Cancer Cooperative Group 82b Trial. N Engl J Med (1997) 10.83

Postoperative radiotherapy in high-risk postmenopausal breast-cancer patients given adjuvant tamoxifen: Danish Breast Cancer Cooperative Group DBCG 82c randomised trial. Lancet (1999) 8.44

Pretreatment oxygenation predicts radiation response in advanced squamous cell carcinoma of the head and neck. Radiother Oncol (1996) 3.59

Why actuarial estimates should be used in reporting late normal-tissue effects of cancer treatment ... now! Int J Radiat Oncol Biol Phys (1995) 3.05

Steepness of the dose-response curve as a function of volume in an experimental tumor irradiated under ambient or hypoxic conditions. Int J Radiat Oncol Biol Phys (1997) 2.48

Prognosis after head injury based on early clinical examination. Lancet (1973) 1.67

Quantification of angiogenesis as a prognostic marker in human carcinomas: a critical evaluation of histopathological methods for estimation of vascular density. Eur J Cancer (2003) 1.66

The natural history of prostate carcinoma based on a Danish population treated with no intent to cure. Cancer (1997) 1.63

A confirmatory prognostic study on oxygenation status and loco-regional control in advanced head and neck squamous cell carcinoma treated by radiation therapy. Radiother Oncol (2000) 1.61

Morbidity and mortality of ischaemic heart disease in high-risk breast-cancer patients after adjuvant postmastectomy systemic treatment with or without radiotherapy: analysis of DBCG 82b and 82c randomised trials. Radiotherapy Committee of the Danish Breast Cancer Cooperative Group. Lancet (1999) 1.58

The prognostic relevance of estimates of proliferative activity in early breast cancer. Histopathology (2003) 1.58

Simultaneous and sequential hyperthermia and radiation treatment of an experimental tumor and its surrounding normal tissue in vivo. Int J Radiat Oncol Biol Phys (1980) 1.55

Uveal and conjunctival malignant melanoma in Denmark, 1943-97: incidence and validation study. Ophthalmic Epidemiol (2005) 1.48

Overcoming tumour radiation resistance resulting from acute hypoxia. Eur J Cancer (1992) 1.43

Validity of breast cancer in the Danish Cancer Registry. A study based on clinical records from one county in Denmark. Eur J Cancer Prev (2002) 1.43

Hypoxia in human soft tissue sarcomas: adverse impact on survival and no association with p53 mutations. Br J Cancer (2001) 1.42

Hyperthermia as an adjuvant to radiation therapy of recurrent or metastatic malignant melanoma. A multicentre randomized trial by the European Society for Hyperthermic Oncology. 1996. Int J Hyperthermia (2009) 1.39

Microvessel density predicts survival in prostate cancer patients subjected to watchful waiting. Br J Cancer (1998) 1.38

Radiotherapy-related lung fibrosis enhanced by tamoxifen. J Natl Cancer Inst (1996) 1.37

Effect of hyperthermia on malignant cells in vivo. A review and a hypothesis. Cancer (1977) 1.36

Cancer of the nasal cavity and paranasal sinuses. A clinico-pathological study of 277 patients. Acta Oncol (1997) 1.36

Association between immunohistochemical expression of vascular endothelial growth factor (VEGF), VEGF-expressing neuroendocrine-differentiated tumor cells, and outcome in prostate cancer patients subjected to watchful waiting. Clin Cancer Res (2000) 1.24

Postoperative radiotherapy in Dukes' B and C carcinoma of the rectum and rectosigmoid. A randomized multicenter study. Cancer (1986) 1.22

Cerebral circulation after head injury. 1. Cerebral blood flow and its regulation after closed head injury with emphasis on clinical correlations. J Neurosurg (1974) 1.21

Sensori-neural hearing loss in patients treated with irradiation for nasopharyngeal carcinoma. Int J Radiat Oncol Biol Phys (1991) 1.18

A future for hyperthermia in cancer treatment? Eur J Cancer (2001) 1.17

Early and late radiotherapeutic morbidity in 442 consecutive patients with locally advanced carcinoma of the uterine cervix. Int J Radiat Oncol Biol Phys (1994) 1.15

Heterogeneity in the clinical phenotype of TP53 mutations in breast cancer patients. Clin Cancer Res (2000) 1.13

Waiting times for diagnosis and treatment of head and neck cancer in Denmark in 2010 compared to 1992 and 2002. Eur J Cancer (2012) 1.12

Primary radiotherapy of larynx and pharynx carcinoma--an analysis of some factors influencing local control and survival. Int J Radiat Oncol Biol Phys (1986) 1.12

The relationship between tumor oxygenation and cell proliferation in human soft tissue sarcomas. Int J Radiat Oncol Biol Phys (1996) 1.11

Late treatment-related morbidity in breast cancer patients randomized to postmastectomy radiotherapy and systemic treatment versus systemic treatment alone. Acta Oncol (2000) 1.11

Pharyngo-cutaneous fistulae after laryngectomy. Influence of previous radiotherapy and prophylactic metronidazole. Cancer (1988) 1.11

Postirradiation sensorineural hearing loss: a common but ignored late radiation complication. Int J Radiat Oncol Biol Phys (1996) 1.10

Hydralazine-induced enhancement of hyperthermic damage in a C3H mammary carcinoma in vivo. Int J Hyperthermia (1989) 1.09

Chroma-Memo-Flow technique for rapid sequential analysis of regional cerebral blood flow (rCBF) responses. Can J Neurol Sci (1978) 1.08

Mechanism of action of the selective tumor radiosensitizer nicotinamide. Int J Radiat Oncol Biol Phys (1988) 1.08

Risk of radiation-induced subcutaneous fibrosis in relation to single nucleotide polymorphisms in TGFB1, SOD2, XRCC1, XRCC3, APEX and ATM--a study based on DNA from formalin fixed paraffin embedded tissue samples. Int J Radiat Biol (2006) 1.08

Relationship between the in vitro radiosensitivity of skin fibroblasts and the expression of subcutaneous fibrosis, telangiectasia, and skin erythema after radiotherapy. Radiother Oncol (1996) 1.07

Clinical radiobiology of malignant melanoma. Radiother Oncol (1989) 1.07

Nicotinamide pharmacokinetics in humans and mice: a comparative assessment and the implications for radiotherapy. Radiother Oncol (1993) 1.06

Malignant parotid tumors in 110 consecutive patients: treatment results and prognosis. Laryngoscope (1992) 1.06

Interaction between combretastatin A-4 disodium phosphate and radiation in murine tumors. Radiother Oncol (2001) 1.06

The value of pretreatment cell kinetic parameters as predictors for radiotherapy outcome in head and neck cancer: a multicenter analysis. Radiother Oncol (1999) 1.05

A comprehensive assessment of geographic variation in heat tolerance and hardening capacity in populations of Drosophila melanogaster from eastern Australia. J Evol Biol (2010) 1.05

Seasonal acquisition of chill tolerance and restructuring of membrane glycerophospholipids in an overwintering insect: triggering by low temperature, desiccation and diapause progression. J Exp Biol (2006) 1.03

Measurement of human tumour oxygenation status by a polarographic needle electrode. An analysis of inter- and intratumour heterogeneity. Acta Oncol (1994) 1.03

Effect of cancer chemotherapy on the hypoxic fraction of a solid tumor measured using a local tumor control assay. Radiother Oncol (1988) 1.02

Prognostic significance of urokinase-type plasminogen activator and plasminogen activator inhibitor-1 in primary breast cancer. Br J Cancer (1998) 1.01

Importance of overall treatment time for the outcome of radiotherapy of advanced head and neck carcinoma: dependency on tumor differentiation. Radiother Oncol (1997) 1.01

The effect of combretastatin A-4 disodium phosphate in a C3H mouse mammary carcinoma and a variety of murine spontaneous tumors. Int J Radiat Oncol Biol Phys (1998) 1.00

Effect of hydralazine in spontaneous tumours assessed by oxygen electrodes and 31P-magnetic resonance spectroscopy. Br J Cancer Suppl (1996) 1.00

Treatment of morbidity associated with the management of the axilla in breast-conserving therapy. Acta Oncol (2000) 1.00

Comparative effects of combretastatin A-4 disodium phosphate and 5,6-dimethylxanthenone-4-acetic acid on blood perfusion in a murine tumour and normal tissues. Int J Radiat Biol (2001) 1.00

Patterns of angiogenesis in nonsmall-cell lung carcinoma. Cancer (2001) 0.99

Improving the radiation response in a C3H mouse mammary carcinoma by normobaric oxygen or carbogen breathing. Int J Radiat Oncol Biol Phys (1992) 0.98

Invasive oxygen measurements and pimonidazole labeling in human cervix carcinoma. Int J Radiat Oncol Biol Phys (2001) 0.98

Squamous cell carcinoma of the oropharynx: an analysis of 213 consecutive patients scheduled for primary radiotherapy. Laryngoscope (1990) 0.98

Squamous cell carcinoma of the oropharynx--an analysis of treatment results in 289 consecutive patients. Acta Oncol (2000) 0.97

Molecular genetic analysis of easily accessible breast tumour DNA, purified from tissue left over from hormone receptor measurement. APMIS (1998) 0.97

Allelic loss of 16q23.2-24.2 is an independent marker of good prognosis in primary breast cancer. Cancer Res (1998) 0.97

Improved tumor response by combining radiation and the vascular-damaging drug 5,6-dimethylxanthenone-4-acetic acid. Radiat Res (2001) 0.96

Investigations on the possibility of a thermic tumour therapy. I. Short-wave treatment of a transplanted isologous mouse mammary carcinoma. Eur J Cancer (1972) 0.96

Combination of nicotinamide and hyperthermia to eliminate radioresistant chronically and acutely hypoxic tumor cells. Cancer Res (1990) 0.96

Risk factors of arm lymphedema in breast cancer patients. Acta Oncol (2000) 0.96

Tissue microarrays compared with whole sections and biochemical analyses. A subgroup analysis of DBCG 82 b&c. Acta Oncol (2008) 0.95

DNA ploidy and survival of patients with clinically localized prostate cancer treated without intent to cure. Prostate (1998) 0.95

Time-temperature relationship th hyperthermic treatment of malignant and normal tissue in vivo. Cancer Res (1979) 0.95

Some factors of importance in the radiation treatment of malignant melanoma. Radiother Oncol (1986) 0.95

Time trends and regional differences in registration, stage distribution, surgical management and survival of breast cancer in Denmark. Eur J Cancer (2003) 0.94

Feasibility of detecting hypoxia in experimental mouse tumours with 18F-fluorinated tracers and positron emission tomography--a study evaluating [18F]Fluoro-2-deoxy-D-glucose. Acta Oncol (2000) 0.94

Clinical correlations between late normal tissue endpoints after radiotherapy: implications for predictive assays of radiosensitivity. Eur J Cancer (1993) 0.94

Multipole electron-density modelling of synchrotron powder diffraction data: the case of diamond. Acta Crystallogr A (2010) 0.94

Time to loco-regional recurrence after resection of Dukes' B and C colorectal cancer with or without adjuvant postoperative radiotherapy. A multivariate regression analysis. Br J Cancer (1992) 0.94

PET hypoxia imaging with FAZA: reproducibility at baseline and during fractionated radiotherapy in tumour-bearing mice. Eur J Nucl Med Mol Imaging (2012) 0.93

Clinical radiobiology of squamous cell carcinoma of the oropharynx. Int J Radiat Oncol Biol Phys (1991) 0.93

The influence of hypoxia and acidity on the hyperthermic response of malignant cells in vitro. Radiology (1977) 0.93

Long-term colorectal function after postoperative radiotherapy for colorectal cancer. Lancet (1997) 0.92

Radiation treatment of malignant melanoma. Int J Radiat Oncol Biol Phys (1980) 0.92

Relationship between radiobiological hypoxia in tumors and electrode measurements of tumor oxygenation. Int J Radiat Oncol Biol Phys (1994) 0.92

Postoperative radiotherapy in rectosigmoid cancer Dukes' B and C: interim report from a randomized multicentre study. Br J Cancer (1982) 0.92

Investigation on the possibility of a thermic tumour therapy. II. Action of combined heat-roentgen treatment on a transplanted mouse mammary carcinoma. Eur J Cancer (1972) 0.92

Relationship between DNA double-strand breaks, cell killing, and fibrosis studied in confluent skin fibroblasts derived from breast cancer patients. Int J Radiat Oncol Biol Phys (2000) 0.91

Influence of extracellular pH on the viability and morphology of tumor cells exposed to hyperthermia. J Natl Cancer Inst (1976) 0.91

Effect of misonidazole and hyperthermia on the radiosensitivity of a C3H mouse mammary carcinoma and its surrounding normal tissue. Br J Cancer (1980) 0.91

Cerebral circulation after head injury. Part 3: Does reduced regional cerebral blood flow determine recovery of brain function after blunt head injury? J Neurosurg (1981) 0.91

Tumor cell proliferation and survival in patients with prostate cancer followed expectantly. J Urol (1998) 0.90

Expression of integrins and E-cadherin in squamous cell carcinomas of the head and neck. APMIS (2004) 0.90

Relationship between the hydralazine-induced changes in murine tumor blood supply and mouse blood pressure. Int J Radiat Oncol Biol Phys (1992) 0.90

Relationship between tumour cell in vitro radiosensitivity and clinical outcome after curative radiotherapy for squamous cell carcinoma of the head and neck. Radiother Oncol (1999) 0.90

Hypopharyngeal squamous cell carcinoma--treatment results in 138 consecutively admitted patients. Acta Oncol (2000) 0.90

p53 accumulation associated with bcl-2, the proliferation marker MIB-1 and survival in patients with prostate cancer subjected to watchful waiting. J Urol (2000) 0.89

Evidence for a positive correlation between in vitro radiosensitivity of normal human skin fibroblasts and the occurrence of subcutaneous fibrosis after radiotherapy. Int J Radiat Biol (1994) 0.89

Cerebral circulation after head injury. Part 2: The effects of traumatic brain edema. J Neurosurg (1976) 0.89

Can mild hyperthermia improve tumour oxygenation? Int J Hyperthermia (1997) 0.89

Studies of the association of the GNB3 825C>T polymorphism with components of the metabolic syndrome in white Danes. Diabetologia (2005) 0.89

Relationship between radiobiological hypoxia and direct estimates of tumour oxygenation in a mouse tumour model. Radiother Oncol (1993) 0.88

A randomized study comparing two high-dose per fraction radiation schedules in recurrent or metastatic malignant melanoma. Int J Radiat Oncol Biol Phys (1985) 0.88

Effect of carbon monoxide breathing on hypoxia and radiation response in the SCCVII tumor in vivo. Int J Radiat Oncol Biol Phys (1994) 0.88

Reducing acute and chronic hypoxia in tumours by combining nicotinamide with carbogen breathing. Acta Oncol (1994) 0.88