Published in BMJ on May 10, 2007
The diagnostic value of symptoms for colorectal cancer in primary care: a systematic review. Br J Gen Pract (2011) 3.79
The CAPER studies: five case-control studies aimed at identifying and quantifying the risk of cancer in symptomatic primary care patients. Br J Cancer (2009) 3.43
Non-visible versus visible haematuria and bladder cancer risk: a study of electronic records in primary care. Br J Gen Pract (2014) 2.53
Do diagnostic delays in cancer matter? Br J Cancer (2009) 2.26
Cancer diagnosis in primary care. Br J Gen Pract (2010) 2.24
Positive predictive values of ≥5% in primary care for cancer: systematic review. Br J Gen Pract (2010) 2.15
Is investigation of patients with haemoptysis and normal chest radiograph justified? Thorax (2009) 2.15
Five misconceptions in cancer diagnosis. Br J Gen Pract (2009) 2.07
Identifying women with suspected ovarian cancer in primary care: derivation and validation of algorithm. BMJ (2011) 2.03
Clinical features of bladder cancer in primary care. Br J Gen Pract (2012) 1.89
Symptoms and risk factors to identify men with suspected cancer in primary care: derivation and validation of an algorithm. Br J Gen Pract (2013) 1.84
Symptoms and risk factors to identify women with suspected cancer in primary care: derivation and validation of an algorithm. Br J Gen Pract (2013) 1.82
Predictive values of GPs' suspicion of serious disease: a population-based follow-up study. Br J Gen Pract (2014) 1.77
The risk of colorectal cancer with symptoms at different ages and between the sexes: a case-control study. BMC Med (2009) 1.76
Comparison of cancer diagnostic intervals before and after implementation of NICE guidelines: analysis of data from the UK General Practice Research Database. Br J Cancer (2013) 1.71
Identifying patients with suspected colorectal cancer in primary care: derivation and validation of an algorithm. Br J Gen Pract (2012) 1.67
Attributions of cancer 'alarm' symptoms in a community sample. PLoS One (2014) 1.64
Identifying patients with suspected pancreatic cancer in primary care: derivation and validation of an algorithm. Br J Gen Pract (2012) 1.63
Identifying patients with suspected gastro-oesophageal cancer in primary care: derivation and validation of an algorithm. Br J Gen Pract (2011) 1.63
Dealing with low-incidence serious diseases in general practice. Br J Gen Pract (2011) 1.58
The frequency of diagnostic errors in outpatient care: estimations from three large observational studies involving US adult populations. BMJ Qual Saf (2014) 1.55
Alarm symptoms and identification of non-cancer diagnoses in primary care: cohort study. BMJ (2009) 1.54
Identifying patients with suspected renal tract cancer in primary care: derivation and validation of an algorithm. Br J Gen Pract (2012) 1.42
Determining the date of diagnosis--is it a simple matter? The impact of different approaches to dating diagnosis on estimates of delayed care for ovarian cancer in UK primary care. BMC Med Res Methodol (2009) 1.41
Identifying patients with suspected lung cancer in primary care: derivation and validation of an algorithm. Br J Gen Pract (2011) 1.35
Identifying patients with undetected colorectal cancer: an independent validation of QCancer (Colorectal). Br J Cancer (2012) 1.28
The interface of primary and oncology specialty care: from symptoms to diagnosis. J Natl Cancer Inst Monogr (2010) 1.26
Features of childhood cancer in primary care: a population-based nested case-control study. Br J Cancer (2012) 1.23
Risk of childhood cancer with symptoms in primary care: a population-based case-control study. Br J Gen Pract (2013) 1.20
How frequently do young people with potential cancer symptoms present in primary care? Br J Gen Pract (2011) 1.18
The risk of oesophago-gastric cancer in symptomatic patients in primary care: a large case-control study using electronic records. Br J Cancer (2012) 1.18
Exploring situational awareness in diagnostic errors in primary care. BMJ Qual Saf (2011) 1.17
Prevalence of cancer alarm symptoms: a population-based cross-sectional study. Scand J Prim Health Care (2010) 1.17
How does the thought of cancer arise in a general practice consultation? Interviews with GPs. Scand J Prim Health Care (2012) 1.16
Care of Terminally Ill Cancer Patients: An Intensivist's Dilemma. Indian J Palliat Care (2010) 1.14
Early diagnosis of cancer--the role of general practice. Scand J Prim Health Care (2009) 1.11
Clinical features of kidney cancer in primary care: a case-control study using primary care records. Br J Gen Pract (2013) 1.09
Cancer suspicion in general practice, urgent referral and time to diagnosis: a population-based GP survey and registry study. BMC Cancer (2014) 1.08
Implementing and maintaining a researchable database from electronic medical records: a perspective from an academic family medicine department. Healthc Policy (2009) 1.07
Understanding missed opportunities for more timely diagnosis of cancer in symptomatic patients after presentation. Br J Cancer (2015) 1.06
Gender inequalities in the promptness of diagnosis of bladder and renal cancer after symptomatic presentation: evidence from secondary analysis of an English primary care audit survey. BMJ Open (2013) 1.06
Diagnosis delay in Libyan female breast cancer. BMC Res Notes (2012) 1.05
The risk of a subsequent cancer diagnosis after herpes zoster infection: primary care database study. Br J Cancer (2013) 1.02
Existing data sources for clinical epidemiology: Danish Cancer in Primary Care cohort. Clin Epidemiol (2014) 1.00
General practice by numbers: presentation to final outcome. Br J Gen Pract (2013) 0.97
The predictive value of cancer symptoms in primary care. Br J Gen Pract (2010) 0.96
A differentiated approach to referrals from general practice to support early cancer diagnosis - the Danish three-legged strategy. Br J Cancer (2015) 0.95
General practitioners' role in cancer care: a French-Norwegian study. BMC Res Notes (2009) 0.94
Are alarm symptoms predictive of cancer survival?: population-based cohort study. Br J Gen Pract (2013) 0.94
The relative length of the patient and the primary care interval in patients with 28 common and rarer cancers. Br J Cancer (2015) 0.93
Self-reported symptoms and healthcare seeking in the general population--exploring "The Symptom Iceberg". BMC Public Health (2015) 0.92
Alarm symptoms of soft-tissue and bone sarcoma in patients referred to a specialist center. Acta Orthop (2014) 0.92
Symptoms, signs, and tests: The general practitioner's comprehensive approach towards a cancer diagnosis. Scand J Prim Health Care (2015) 0.89
Health services research in the public healthcare system in Hong Kong: an analysis of over 1 million antihypertensive prescriptions between 2004-2007 as an example of the potential and pitfalls of using routinely collected electronic patient data. BMC Health Serv Res (2008) 0.88
Cancer diagnosed by emergency admission in England: an observational study using the general practice research database. BMC Health Serv Res (2013) 0.88
Use of primary care during the year before childhood cancer diagnosis: a nationwide population-based matched comparative study. PLoS One (2013) 0.87
A geographical cluster randomised stepped wedge study of continuing medical education and cancer diagnosis in general practice. Implement Sci (2014) 0.85
The Role of Physicians' First Impressions in the Diagnosis of Possible Cancers without Alarm Symptoms. Med Decis Making (2016) 0.83
Systematic review of clinical features of suspected colorectal cancer in primary care. Can Fam Physician (2014) 0.83
The Danish Symptom Cohort: Questionnaire and Feasibility in the Nationwide Study on Symptom Experience and Healthcare-Seeking among 100 000 Individuals. Int J Family Med (2014) 0.83
What prompts help-seeking for cancer 'alarm' symptoms? A primary care based survey. Br J Cancer (2016) 0.82
Low cancer suspicion following experience of a cancer 'warning sign'. Eur J Cancer (2015) 0.82
Associations between reporting of cancer alarm symptoms and socioeconomic and demographic determinants: a population-based, cross-sectional study. BMC Public Health (2012) 0.80
Age and Gender Variations in Cancer Diagnostic Intervals in 15 Cancers: Analysis of Data from the UK Clinical Practice Research Datalink. PLoS One (2015) 0.80
Alarm symptoms in primary care. BMJ (2007) 0.80
Referrals for suspected hematologic malignancy: a survey of primary care physicians. Am J Hematol (2012) 0.79
Systematic review of guidelines for the management of suspected lung cancer in primary care. Can Fam Physician (2014) 0.79
The association between symptoms and bladder or renal tract cancer in primary care: a systematic review. Br J Gen Pract (2015) 0.78
Risk prediction models for colorectal cancer in people with symptoms: a systematic review. BMC Gastroenterol (2016) 0.78
Commentary: Diagnosing ovarian cancer--more problems than answers. BMJ (2009) 0.78
Disparities in evaluation of patients with rectal bleeding 40 years and older. Clin Gastroenterol Hepatol (2013) 0.77
Multiple perspectives on symptom interpretation in primary care research. BMC Fam Pract (2013) 0.77
Electronic Trigger-Based Intervention to Reduce Delays in Diagnostic Evaluation for Cancer: A Cluster Randomized Controlled Trial. J Clin Oncol (2015) 0.76
Jeremy Hunt's bizarre ideas show that he doesn't understand general practice. BMJ (2014) 0.75
Impact of a continuing medical education meeting on the use and timing of urgent cancer referrals among general practitioners - a before-after study. BMC Fam Pract (2017) 0.75
Improving early diagnosis of symptomatic cancer. Nat Rev Clin Oncol (2016) 0.75
How the probability of presentation to a primary care clinician correlates with cancer survival rates: a European survey using vignettes. Scand J Prim Health Care (2017) 0.75
Lessons from Mackenzie that still resonate. Br J Gen Pract (2013) 0.75
Family history assessment for colorectal cancer (CRC) risk analysis - comparison of diagram- and questionnaire-based web interfaces. BMC Med Inform Decis Mak (2015) 0.75
Lower Gastrointestinal Bleeding And Risk of Gastrointestinal Cancer. Clin Transl Gastroenterol (2016) 0.75
Is real world evidence influencing practice? A systematic review of CPRD research in NICE guidances. BMC Health Serv Res (2016) 0.75
Delay in Cancer Diagnosis: Causes and Possible Solutions. Oman Med J (2016) 0.75
Increased consultation frequency in primary care, a risk marker for cancer: a case-control study. Scand J Prim Health Care (2016) 0.75
Validation of information recorded on general practitioner based computerised data resource in the United Kingdom. BMJ (1991) 17.91
The Montreal definition and classification of gastroesophageal reflux disease: a global evidence-based consensus. Am J Gastroenterol (2006) 12.80
Is the two week rule for cancer referrals working? BMJ (2001) 7.90
Validity of the general practice research database. Pharmacotherapy (2003) 6.78
Clinical features of colorectal cancer before diagnosis: a population-based case-control study. Br J Cancer (2005) 4.19
Variation in GP referral rates: what can we learn from the literature? Fam Pract (2000) 4.11
Predictive value of signs and symptoms for colorectal cancer in patients with rectal bleeding in general practice. Fam Pract (1995) 3.82
What are the clinical features of lung cancer before the diagnosis is made? A population based case-control study. Thorax (2005) 3.66
Rectal bleeding and colorectal cancer in general practice: diagnostic study. BMJ (2000) 3.46
An evidence-based appraisal of reflux disease management--the Genval Workshop Report. Gut (1999) 3.45
The diagnostic value of macroscopic haematuria for the diagnosis of urological cancer in general practice. Br J Gen Pract (2003) 3.15
Patients with new onset haematuria: assessing the discriminant value of clinical information in relation to urological malignancies. Br J Gen Pract (2002) 3.01
The diagnostic value of macroscopic haematuria in diagnosing urological cancers: a meta-analysis. Fam Pract (1997) 2.86
Diagnosis of colorectal cancer in primary care: the evidence base for guidelines. Fam Pract (2004) 2.61
Factors identifying higher risk rectal bleeding in general practice. Br J Gen Pract (2005) 2.59
Hemoptysis: etiology, evaluation, and outcome in a tertiary referral hospital. Chest (1997) 2.47
Limited value of alarm features in the diagnosis of upper gastrointestinal malignancy: systematic review and meta-analysis. Gastroenterology (2006) 2.46
Case-mix and variation in specialist referrals in general practice. Br J Gen Pract (2005) 2.29
Clinical features of prostate cancer before diagnosis: a population-based, case-control study. Br J Gen Pract (2006) 2.20
'There's a lot of it about': clinical strategies in family practice. J R Coll Gen Pract (1986) 2.17
Rectal bleeding: prevalence and consultation behaviour. BMJ (1995) 2.11
Risk in primary care of colorectal cancer from new onset rectal bleeding: 10 year prospective study. BMJ (2006) 2.07
'Alarm symptoms' in patients with dyspepsia: a three-year prospective study from general practice. Scand J Gastroenterol (2002) 2.06
The yield and the predictors of esophageal pathology when upper endoscopy is used for the initial evaluation of dysphagia. Gastrointest Endosc (2005) 1.93
Diagnosis of lung cancer in primary care: a structured review. Fam Pract (2004) 1.77
Predictive value of alarm features in a rapid access upper gastrointestinal cancer service. Gut (2005) 1.56
Risk of colorectal cancer in general practice patients presenting with rectal bleeding, change in bowel habit or anaemia. Eur J Cancer Care (Engl) (2006) 1.45
Predictive value of rectal bleeding in screening for rectal and sigmoid polyps. Br Med J (Clin Res Ed) (1985) 1.36
Hemoptysis: a retrospective analysis of 108 cases. Respir Med (2002) 1.09
Predictive value of rectal bleeding for distal colonic neoplastic lesions in a screened population. Eur J Cancer (2004) 1.07
Comparison of predictive value for colorectal cancer in subjects with and without rectal bleeding. Hepatogastroenterology (1999) 0.91
Patterns of intra-cluster correlation from primary care research to inform study design and analysis. J Clin Epidemiol (2004) 5.44
Why has antibiotic prescribing for respiratory illness declined in primary care? A longitudinal study using the General Practice Research Database. J Public Health (Oxf) (2004) 3.19
Within-person study designs had lower precision and greater susceptibility to bias because of trends in exposure than cohort and nested case-control designs. J Clin Epidemiol (2011) 2.64
Place of medical qualification and outcomes of UK General Medical Council "fitness to practise" process: cohort study. BMJ (2011) 2.44
Variations in antibiotic prescribing and consultation rates for acute respiratory infection in UK general practices 1995-2000. Br J Gen Pract (2005) 2.28
Impact and cost-effectiveness of a universal strategy to promote physical activity in primary care: population-based cohort study and Markov model. Eur J Health Econ (2013) 2.17
Selection of medical diagnostic codes for analysis of electronic patient records. Application to stroke in a primary care database. PLoS One (2009) 2.07
Use of antihypertensive medications and mortality of patients with autosomal dominant polycystic kidney disease: a population-based study. Am J Kidney Dis (2011) 2.05
Incidence of type 2 diabetes after bariatric surgery: population-based matched cohort study. Lancet Diabetes Endocrinol (2014) 1.65
Cluster randomised trial in the General Practice Research Database: 1. Electronic decision support to reduce antibiotic prescribing in primary care (eCRT study). Trials (2011) 1.61
Is relative mortality of type 2 diabetes mellitus decreasing? Am J Epidemiol (2008) 1.58
Alarm symptoms and identification of non-cancer diagnoses in primary care: cohort study. BMJ (2009) 1.54
Declining 1-year case-fatality of stroke and increasing coverage of vascular risk management: population-based cohort study. J Neurol Neurosurg Psychiatry (2010) 1.51
Selective decrease in consultations and antibiotic prescribing for acute respiratory tract infections in UK primary care up to 2006. J Public Health (Oxf) (2009) 1.49
Positive screening and carrier results for the England-wide universal newborn sickle cell screening programme by ethnicity and area for 2005-07. J Clin Pathol (2010) 1.41
Coding, recording and incidence of different forms of coronary heart disease in primary care. PLoS One (2012) 1.39
Incidence, mortality, and disease associations of pyoderma gangrenosum in the United Kingdom: a retrospective cohort study. J Invest Dermatol (2012) 1.36
Delay between pregnancy confirmation and sickle cell and [corrected] thalassaemia screening: a population-based cohort study. Br J Gen Pract (2008) 1.33
Explaining the decline in early mortality in men and women with type 2 diabetes: a population-based cohort study. Diabetes Care (2008) 1.27
Utility of electronic patient records in primary care for stroke secondary prevention trials. BMC Public Health (2011) 1.27
Ethnic variations in the prevalence of diabetic retinopathy in people with diabetes attending screening in the United Kingdom (DRIVE UK). PLoS One (2012) 1.20
Increasing socio-economic inequality in type 2 diabetes prevalence--repeated cross-sectional surveys in England 1994-2006. Eur J Public Health (2010) 1.19
Sudden infant death syndrome and maternal depression. J Clin Psychiatry (2007) 1.17
Cardiovascular risk factors and cognitive decline in adults aged 50 and over: a population-based cohort study. Age Ageing (2012) 1.16
Population intermediate outcomes of diabetes under pay-for-performance incentives in England from 2004 to 2008. Diabetes Care (2008) 1.13
Impact of body mass index on prevalence of multimorbidity in primary care: cohort study. Fam Pract (2013) 1.13
Risk of diabetes associated with prescribed glucocorticoids in a large population. Diabetes Care (2006) 1.11
Explaining inequalities in access to treatment in lung cancer. J Eval Clin Pract (2006) 1.06
Trends in hospital admissions for sickle cell disease in England. J Public Health (Oxf) (2013) 1.06
Validity of smoking prevalence estimates from primary care electronic health records compared with national population survey data for England, 2007 to 2011. Pharmacoepidemiol Drug Saf (2013) 1.04
Epilepsy mortality and risk factors for death in epilepsy: a population-based study. Br J Gen Pract (2011) 1.04
A simulation study of odds ratio estimation for binary outcomes from cluster randomized trials. Stat Med (2007) 1.03
Variations in the organization and delivery of the 'NHS health check' in primary care. J Public Health (Oxf) (2012) 1.02
Non-parametric bootstrap confidence intervals for the intraclass correlation coefficient. Stat Med (2003) 1.02
Cluster randomized trials utilizing primary care electronic health records: methodological issues in design, conduct, and analysis (eCRT Study). Trials (2014) 1.00
Comparison of the risk difference, risk ratio and odds ratio scales for quantifying the unadjusted intervention effect in cluster randomized trials. Stat Med (2008) 0.98
How important is vehicle safety in the new vehicle purchase process? Accid Anal Prev (2007) 0.94
Trends in antiepileptic drug utilisation in UK primary care 1993-2008: cohort study using the General Practice Research Database. Seizure (2012) 0.94
Epidemiology of clinical body mass index recording in an obese population in primary care: a cohort study. J Public Health (Oxf) (2012) 0.93
Protocol for Candrive II/Ozcandrive, a multicentre prospective older driver cohort study. Accid Anal Prev (2013) 0.93
Are child occupants a significant source of driving distraction? Accid Anal Prev (2011) 0.92
Riding through red lights: the rate, characteristics and risk factors of non-compliant urban commuter cyclists. Accid Anal Prev (2010) 0.91
No association between immunization and Guillain-Barré syndrome in the United Kingdom, 1992 to 2000. Arch Intern Med (2006) 0.90
Why do cyclists infringe at red lights? An investigation of Australian cyclists' reasons for red light infringement. Accid Anal Prev (2012) 0.88
Increased incidence of carpal tunnel syndrome up to 10 years before diagnosis of diabetes. Diabetes Care (2006) 0.88
Antihypertensive treatment after first stroke in primary care: results from the General Practitioner Research Database. J Hypertens (2011) 0.88
Enhanced invitation methods to increase uptake of NHS health checks: study protocol for a randomized controlled trial. Trials (2014) 0.87
Self-awareness following traumatic brain injury and implications for rehabilitation. Brain Inj (2002) 0.86
Increased utilization of primary care 5 years before diagnosis of type 2 diabetes: a matched cohort study. Diabetes Care (2005) 0.86
General health status and functional disability following injury in traffic crashes. Traffic Inj Prev (2007) 0.86
Recent HbA1c values and mortality risk in type 2 diabetes. population-based case-control study. PLoS One (2013) 0.86
Income, wealth and risk of diabetes among older adults: cohort study using the English longitudinal study of ageing. Eur J Public Health (2011) 0.86
Non-attendance at diabetic eye screening and risk of sight-threatening diabetic retinopathy: a population-based cohort study. Diabetologia (2013) 0.86
Driving ability in Parkinson's disease: current status of research. Neurosci Biobehav Rev (2008) 0.85
Effectiveness of interventions to promote healthy diet in primary care: systematic review and meta-analysis of randomised controlled trials. BMC Public Health (2013) 0.84
Changes in detection of retinopathy in type 2 diabetes in the first 4 years of a population-based diabetic eye screening program: retrospective cohort study. Diabetes Care (2013) 0.84
Hospital inpatients' experiences of access to food: a qualitative interview and observational study. Health Expect (2008) 0.83
Confounder-adjusted estimates of the risk difference using propensity score-based weighting. Stat Med (2010) 0.83
Ethnic variation in the prevalence of visual impairment in people attending diabetic retinopathy screening in the United Kingdom (DRIVE UK). PLoS One (2012) 0.82
Is sodium valproate, an HDAC inhibitor, associated with reduced risk of stroke and myocardial infarction? A nested case-control study. Pharmacoepidemiol Drug Saf (2014) 0.82
The relationship between perceived crash responsibility and post-crash depression. Annu Proc Assoc Adv Automot Med (2005) 0.82
An Australasian model license reassessment procedure for identifying potentially unsafe drivers. Traffic Inj Prev (2008) 0.82
Evaluation of equity in diabetes health care in relation to African and Caribbean ethnicity. Ethn Health (2003) 0.82
The impacts of functional performance, behaviour and traffic exposure on road-crossing judgements of young children. Annu Proc Assoc Adv Automot Med (2007) 0.82
Investigating driving behaviour of older drivers with mild cognitive impairment using a portable driving simulator. Accid Anal Prev (2012) 0.81
Diabetes diagnosis, resource utilization, and health outcomes. Am J Manag Care (2008) 0.81
Food insecurity and low income in an English inner city. J Public Health Med (2003) 0.81
Comment on 'Bariatric Surgery Can Lead to Net Cost Savings to Health Care Systems: Results from a Comprehensive European Decision Analytic Model'. Obes Surg (2015) 0.81
Implications of vision testing for older driver licensing. Traffic Inj Prev (2008) 0.81
Mortality in type 2 diabetic subjects prescribed metformin and sulphonylurea drugs in combination: cohort study. Diabetes Metab Res Rev (2004) 0.81
How important is vehicle safety in the new vehicle purchase/lease process for fleet vehicles? Traffic Inj Prev (2007) 0.81
Driving responses of older and younger drivers in a driving simulator. Annu Proc Assoc Adv Automot Med (2007) 0.80
Does the influence of stroke on dementia vary by different levels of prestroke cognitive functioning?: a cohort study. Stroke (2013) 0.80
The Candrive/Ozcandrive prospective older driver study: Methodology and early study findings. Accid Anal Prev (2013) 0.80
Trends in cardiovascular risk factors among people with diabetes in a population based study, Health Survey for England 1994-2009. Prim Care Diabetes (2013) 0.79
Potential application of item-response theory to interpretation of medical codes in electronic patient records. BMC Med Res Methodol (2011) 0.79
Heritabilities and shared environmental effects were estimated from household clustering in national health survey data. J Clin Epidemiol (2006) 0.79
Is illicit drug use harmful to cognitive functioning in the midadult years? A cohort-based investigation. Am J Epidemiol (2011) 0.79
Fracture risk with use of liver enzyme inducing antiepileptic drugs in people with active epilepsy: cohort study using the general practice research database. Seizure (2012) 0.78
Predictive validity of different definitions of hypertension for type 2 diabetes. Diabetes Metab Res Rev (2006) 0.78