Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
1
|
Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection.
|
Proc Natl Acad Sci U S A
|
2008
|
16.54
|
2
|
Genetic identity, biological phenotype, and evolutionary pathways of transmitted/founder viruses in acute and early HIV-1 infection.
|
J Exp Med
|
2009
|
7.01
|
3
|
The first T cell response to transmitted/founder virus contributes to the control of acute viremia in HIV-1 infection.
|
J Exp Med
|
2009
|
6.22
|
4
|
Initial B-cell responses to transmitted human immunodeficiency virus type 1: virion-binding immunoglobulin M (IgM) and IgG antibodies followed by plasma anti-gp41 antibodies with ineffective control of initial viremia.
|
J Virol
|
2008
|
5.24
|
5
|
Low-dose rectal inoculation of rhesus macaques by SIVsmE660 or SIVmac251 recapitulates human mucosal infection by HIV-1.
|
J Exp Med
|
2009
|
4.79
|
6
|
A novel antiviral intervention results in more accurate assessment of human immunodeficiency virus type 1 replication dynamics and T-cell decay in vivo.
|
J Virol
|
2003
|
4.12
|
7
|
Kinetics of influenza A virus infection in humans.
|
J Virol
|
2006
|
3.78
|
8
|
High Multiplicity Infection by HIV-1 in Men Who Have Sex with Men.
|
PLoS Pathog
|
2010
|
3.68
|
9
|
Acute loss of intestinal CD4+ T cells is not predictive of simian immunodeficiency virus virulence.
|
J Immunol
|
2007
|
3.24
|
10
|
Transmission of single HIV-1 genomes and dynamics of early immune escape revealed by ultra-deep sequencing.
|
PLoS One
|
2010
|
3.02
|
11
|
Persistent HIV-1 replication is associated with lower antiretroviral drug concentrations in lymphatic tissues.
|
Proc Natl Acad Sci U S A
|
2014
|
2.95
|
12
|
Rapid emergence of protease inhibitor resistance in hepatitis C virus.
|
Sci Transl Med
|
2010
|
2.82
|
13
|
Modeling shows that the NS5A inhibitor daclatasvir has two modes of action and yields a shorter estimate of the hepatitis C virus half-life.
|
Proc Natl Acad Sci U S A
|
2013
|
2.79
|
14
|
Modelling how ribavirin improves interferon response rates in hepatitis C virus infection.
|
Nature
|
2004
|
2.74
|
15
|
Viral dynamics and response differences in HCV-infected African American and white patients treated with IFN and ribavirin.
|
Hepatology
|
2003
|
2.50
|
16
|
Modeling sequence evolution in acute HIV-1 infection.
|
J Theor Biol
|
2009
|
2.32
|
17
|
Immediate antiviral therapy appears to restrict resting CD4+ cell HIV-1 infection without accelerating the decay of latent infection.
|
Proc Natl Acad Sci U S A
|
2012
|
2.27
|
18
|
The complexity of complexes in signal transduction.
|
Biotechnol Bioeng
|
2003
|
2.20
|
19
|
Vertical T cell immunodominance and epitope entropy determine HIV-1 escape.
|
J Clin Invest
|
2012
|
2.05
|
20
|
Intensification of antiretroviral therapy accelerates the decay of the HIV-1 latent reservoir and decreases, but does not eliminate, ongoing virus replication.
|
J Acquir Immune Defic Syndr
|
2004
|
2.05
|
21
|
Different dynamics of CD4+ and CD8+ T cell responses during and after acute lymphocytic choriomeningitis virus infection.
|
J Immunol
|
2003
|
2.03
|
22
|
Estimation of the initial viral growth rate and basic reproductive number during acute HIV-1 infection.
|
J Virol
|
2010
|
2.02
|
23
|
Kinetics of hepatitis C virus reinfection after liver transplantation.
|
Liver Transpl
|
2006
|
2.01
|
24
|
Triphasic decline of hepatitis C virus RNA during antiviral therapy.
|
Hepatology
|
2007
|
2.00
|
25
|
CD8+ lymphocytes control viral replication in SIVmac239-infected rhesus macaques without decreasing the lifespan of productively infected cells.
|
PLoS Pathog
|
2010
|
1.99
|
26
|
Determining the relative efficacy of highly active antiretroviral therapy.
|
J Infect Dis
|
2003
|
1.90
|
27
|
Modeling hepatitis C virus dynamics: liver regeneration and critical drug efficacy.
|
J Theor Biol
|
2007
|
1.89
|
28
|
Designing a genome-based HIV incidence assay with high sensitivity and specificity.
|
AIDS
|
2011
|
1.88
|
29
|
Second-phase hepatitis C virus RNA decline during telaprevir-based therapy increases with drug effectiveness: implications for treatment duration.
|
Hepatology
|
2011
|
1.87
|
30
|
Turnover rates of B cells, T cells, and NK cells in simian immunodeficiency virus-infected and uninfected rhesus macaques.
|
J Immunol
|
2003
|
1.87
|
31
|
In vivo dynamics of T cell activation, proliferation, and death in HIV-1 infection: why are CD4+ but not CD8+ T cells depleted?
|
Proc Natl Acad Sci U S A
|
2002
|
1.82
|
32
|
Quantifying the early immune response and adaptive immune response kinetics in mice infected with influenza A virus.
|
J Virol
|
2010
|
1.80
|
33
|
Modeling latently infected cell activation: viral and latent reservoir persistence, and viral blips in HIV-infected patients on potent therapy.
|
PLoS Comput Biol
|
2009
|
1.78
|
34
|
Kinetics of virus-specific CD8+ T cells and the control of human immunodeficiency virus infection.
|
J Virol
|
2004
|
1.77
|
35
|
Simulation and prediction of the adaptive immune response to influenza A virus infection.
|
J Virol
|
2009
|
1.76
|
36
|
Early ribavirin pharmacokinetics, HCV RNA and alanine aminotransferase kinetics in HIV/HCV co-infected patients during treatment with pegylated interferon and ribavirin.
|
J Hepatol
|
2007
|
1.74
|
37
|
ON IDENTIFIABILITY OF NONLINEAR ODE MODELS AND APPLICATIONS IN VIRAL DYNAMICS.
|
SIAM Rev Soc Ind Appl Math
|
2011
|
1.69
|
38
|
Pharmacodynamics of PEG-IFN alpha differentiate HIV/HCV coinfected sustained virological responders from nonresponders.
|
Hepatology
|
2006
|
1.69
|
39
|
Polyspecificity of T cell and B cell receptor recognition.
|
Semin Immunol
|
2007
|
1.68
|
40
|
Effect of ribavirin on viral kinetics and liver gene expression in chronic hepatitis C.
|
Gut
|
2013
|
1.63
|
41
|
Early low-titer neutralizing antibodies impede HIV-1 replication and select for virus escape.
|
PLoS Pathog
|
2012
|
1.61
|
42
|
Impact of thymectomy on the peripheral T cell pool in rhesus macaques before and after infection with simian immunodeficiency virus.
|
Eur J Immunol
|
2005
|
1.60
|
43
|
Fitness costs and diversity of the cytotoxic T lymphocyte (CTL) response determine the rate of CTL escape during acute and chronic phases of HIV infection.
|
J Virol
|
2011
|
1.57
|
44
|
Parameter identifiability and estimation of HIV/AIDS dynamic models.
|
Bull Math Biol
|
2008
|
1.56
|
45
|
Drug resistance and influenza pandemics.
|
Lancet
|
2002
|
1.55
|
46
|
Transient viremia, plasma viral load, and reservoir replenishment in HIV-infected patients on antiretroviral therapy.
|
J Acquir Immune Defic Syndr
|
2007
|
1.54
|
47
|
Estimating lymphocyte division and death rates from CFSE data.
|
Bull Math Biol
|
2006
|
1.53
|
48
|
In a subset of subjects on highly active antiretroviral therapy, human immunodeficiency virus type 1 RNA in plasma decays from 50 to <5 copies per milliliter, with a half-life of 6 months.
|
J Virol
|
2003
|
1.53
|
49
|
Modeling long-term HIV dynamics and antiretroviral response: effects of drug potency, pharmacokinetics, adherence, and drug resistance.
|
J Acquir Immune Defic Syndr
|
2005
|
1.52
|
50
|
Viral blip dynamics during highly active antiretroviral therapy.
|
J Virol
|
2003
|
1.51
|
51
|
Short-lived infected cells support virus replication in sooty mangabeys naturally infected with simian immunodeficiency virus: implications for AIDS pathogenesis.
|
J Virol
|
2008
|
1.51
|
52
|
Modeling amantadine treatment of influenza A virus in vitro.
|
J Theor Biol
|
2008
|
1.51
|
53
|
Modeling HIV persistence, the latent reservoir, and viral blips.
|
J Theor Biol
|
2009
|
1.49
|
54
|
Simian immunodeficiency virus SIVagm dynamics in African green monkeys.
|
J Virol
|
2008
|
1.49
|
55
|
Determination of virus burst size in vivo using a single-cycle SIV in rhesus macaques.
|
Proc Natl Acad Sci U S A
|
2007
|
1.48
|
56
|
Mathematical modeling of primary hepatitis C infection: noncytolytic clearance and early blockage of virion production.
|
Gastroenterology
|
2005
|
1.47
|
57
|
HIV-1 infection and low steady state viral loads.
|
Bull Math Biol
|
2002
|
1.46
|
58
|
Discontinuation of antiretroviral therapy commenced early during the course of human immunodeficiency virus type 1 infection, with or without adjunctive vaccination.
|
J Infect Dis
|
2002
|
1.45
|
59
|
Estimating time since infection in early homogeneous HIV-1 samples using a poisson model.
|
BMC Bioinformatics
|
2010
|
1.45
|
60
|
Agent-based modeling of host-pathogen systems: The successes and challenges.
|
Inf Sci (Ny)
|
2009
|
1.43
|
61
|
Multiplicity of human immunodeficiency virus infections in lymphoid tissue.
|
J Virol
|
2004
|
1.43
|
62
|
Complete genetic linkage can subvert natural selection.
|
Proc Natl Acad Sci U S A
|
2007
|
1.42
|
63
|
Mathematical analysis of delay differential equation models of HIV-1 infection.
|
Math Biosci
|
2002
|
1.41
|
64
|
Modeling and estimation of replication fitness of human immunodeficiency virus type 1 in vitro experiments by using a growth competition assay.
|
J Virol
|
2006
|
1.41
|
65
|
Dynamic correlation between intrahost HIV-1 quasispecies evolution and disease progression.
|
PLoS Comput Biol
|
2008
|
1.39
|
66
|
Complex patterns of viral load decay under antiretroviral therapy: influence of pharmacokinetics and intracellular delay.
|
J Theor Biol
|
2004
|
1.39
|
67
|
HIV dynamics with multiple infections of target cells.
|
Proc Natl Acad Sci U S A
|
2005
|
1.36
|
68
|
Acute hepatitis A virus infection is associated with a limited type I interferon response and persistence of intrahepatic viral RNA.
|
Proc Natl Acad Sci U S A
|
2011
|
1.36
|
69
|
Quantifying T lymphocyte turnover.
|
J Theor Biol
|
2013
|
1.35
|
70
|
Viral and latent reservoir persistence in HIV-1-infected patients on therapy.
|
PLoS Comput Biol
|
2006
|
1.35
|
71
|
Naïve and memory cell turnover as drivers of CCR5-to-CXCR4 tropism switch in human immunodeficiency virus type 1: implications for therapy.
|
J Virol
|
2006
|
1.31
|
72
|
Quantifying the diversification of hepatitis C virus (HCV) during primary infection: estimates of the in vivo mutation rate.
|
PLoS Pathog
|
2012
|
1.30
|
73
|
Early hepatitis C viral kinetics correlate with long-term outcome in patients receiving high dose induction followed by combination interferon and ribavirin therapy.
|
J Hepatol
|
2002
|
1.30
|
74
|
Determining the antiviral activity of tenofovir disoproxil fumarate in treatment-naive chronically HIV-1-infected individuals.
|
AIDS
|
2003
|
1.30
|
75
|
Dynamic antibody specificities and virion concentrations in circulating immune complexes in acute to chronic HIV-1 infection.
|
J Virol
|
2011
|
1.28
|
76
|
Elucidation of hepatitis C virus transmission and early diversification by single genome sequencing.
|
PLoS Pathog
|
2012
|
1.28
|
77
|
Hepatitis C virus (HCV) and human immunodeficiency virus (HIV) dynamics during HCV treatment in HCV/HIV coinfection.
|
J Infect Dis
|
2003
|
1.27
|
78
|
Modeling within-host dynamics of influenza virus infection including immune responses.
|
PLoS Comput Biol
|
2012
|
1.26
|
79
|
Characterizing T cell movement within lymph nodes in the absence of antigen.
|
J Immunol
|
2007
|
1.24
|
80
|
Use of laser capture microdissection to map hepatitis C virus-positive hepatocytes in human liver.
|
Gastroenterology
|
2013
|
1.23
|
81
|
Influence of peak viral load on the extent of CD4+ T-cell depletion in simian HIV infection.
|
J Acquir Immune Defic Syndr
|
2006
|
1.23
|
82
|
Estimates of intracellular delay and average drug efficacy from viral load data of HIV-infected individuals under antiretroviral therapy.
|
Antivir Ther
|
2004
|
1.23
|
83
|
Modeling subgenomic hepatitis C virus RNA kinetics during treatment with alpha interferon.
|
J Virol
|
2009
|
1.23
|
84
|
Determining thymic output quantitatively: using models to interpret experimental T-cell receptor excision circle (TREC) data.
|
Immunol Rev
|
2007
|
1.23
|
85
|
Modeling HCV kinetics under therapy using PK and PD information.
|
Expert Opin Drug Metab Toxicol
|
2009
|
1.22
|
86
|
Why are there different dynamics in the selection of drug resistance in HIV and hepatitis B and C viruses?
|
J Antimicrob Chemother
|
2008
|
1.21
|
87
|
Mathematical modeling of subgenomic hepatitis C virus replication in Huh-7 cells.
|
J Virol
|
2006
|
1.21
|
88
|
How antigen quantity and quality determine T-cell decisions in lymphoid tissue.
|
Mol Cell Biol
|
2008
|
1.20
|
89
|
Dynamics of hepatitis B virus infection.
|
Microbes Infect
|
2002
|
1.20
|
90
|
A stochastic model of cytotoxic T cell responses.
|
J Theor Biol
|
2004
|
1.20
|
91
|
The role of cells refractory to productive infection in acute hepatitis B viral dynamics.
|
Proc Natl Acad Sci U S A
|
2007
|
1.19
|
92
|
Influenza A virus infection kinetics: quantitative data and models.
|
Wiley Interdiscip Rev Syst Biol Med
|
2010
|
1.18
|
93
|
Modeling viral and drug kinetics: hepatitis C virus treatment with pegylated interferon alfa-2b.
|
Semin Liver Dis
|
2003
|
1.18
|
94
|
Evolution of hepatitis C viral quasispecies after liver transplantation.
|
Gastroenterology
|
2002
|
1.18
|
95
|
Modeling and estimation of kinetic parameters and replicative fitness of HIV-1 from flow-cytometry-based growth competition experiments.
|
Bull Math Biol
|
2008
|
1.17
|
96
|
Kinetics of coinfection with influenza A virus and Streptococcus pneumoniae.
|
PLoS Pathog
|
2013
|
1.16
|
97
|
Stochastic theory of early viral infection: continuous versus burst production of virions.
|
PLoS Comput Biol
|
2011
|
1.15
|
98
|
Current estimates for HIV-1 production imply rapid viral clearance in lymphoid tissues.
|
PLoS Comput Biol
|
2010
|
1.15
|
99
|
Dynamics of T- and B-lymphocyte turnover in a natural host of simian immunodeficiency virus.
|
J Virol
|
2007
|
1.15
|
100
|
Modeling the long-term control of viremia in HIV-1 infected patients treated with antiretroviral therapy.
|
Math Biosci
|
2004
|
1.14
|
101
|
Viral dynamics during primary simian immunodeficiency virus infection: effect of time-dependent virus infectivity.
|
J Virol
|
2010
|
1.14
|
102
|
Understanding the mechanisms and limitations of immune control of HIV.
|
Immunol Rev
|
2007
|
1.13
|
103
|
Analysis of hepatitis C virus decline during treatment with the protease inhibitor danoprevir using a multiscale model.
|
PLoS Comput Biol
|
2013
|
1.12
|
104
|
Estimating average cellular turnover from 5-bromo-2'-deoxyuridine (BrdU) measurements.
|
Proc Biol Sci
|
2003
|
1.11
|
105
|
Dynamics of alanine aminotransferase during hepatitis C virus treatment.
|
Hepatology
|
2003
|
1.11
|
106
|
A mathematical model of hepatitis C virus dynamics in patients with high baseline viral loads or advanced liver disease.
|
Gastroenterology
|
2009
|
1.11
|
107
|
Opportunistic infection as a cause of transient viremia in chronically infected HIV patients under treatment with HAART.
|
Bull Math Biol
|
2005
|
1.10
|
108
|
Impact of immune escape mutations on HIV-1 fitness in the context of the cognate transmitted/founder genome.
|
Retrovirology
|
2012
|
1.10
|
109
|
Higher level of replication efficiency of 2009 (H1N1) pandemic influenza virus than those of seasonal and avian strains: kinetics from epithelial cell culture and computational modeling.
|
J Virol
|
2010
|
1.09
|
110
|
Understanding triphasic HCV decline during treatment in the era of IL28B polymorphisms and direct acting antiviral agents via mathematical modeling.
|
J Hepatol
|
2012
|
1.09
|
111
|
Innate immune tolerance and the role of kupffer cells in differential responses to interferon therapy among patients with HCV genotype 1 infection.
|
Gastroenterology
|
2012
|
1.09
|
112
|
Modelling hepatitis C virus kinetics: the relationship between the infected cell loss rate and the final slope of viral decay.
|
Antivir Ther
|
2009
|
1.08
|
113
|
Impact of early viral kinetics on T-cell reactivity during antiviral therapy in chronic hepatitis B.
|
Antivir Ther
|
2007
|
1.08
|
114
|
Understanding silibinin's modes of action against HCV using viral kinetic modeling.
|
J Hepatol
|
2012
|
1.08
|
115
|
Mathematical modelling of HCV infection: what can it teach us in the era of direct-acting antiviral agents?
|
Antivir Ther
|
2012
|
1.07
|
116
|
Dynamics of intermittent viremia during highly active antiretroviral therapy in patients who initiate therapy during chronic versus acute and early human immunodeficiency virus type 1 infection.
|
J Virol
|
2004
|
1.06
|
117
|
Hepatitis C Viral Kinetics in the Era of Direct Acting Antiviral Agents and IL28B.
|
Curr Hepat Rep
|
2011
|
1.06
|
118
|
Modeling complex decay profiles of hepatitis B virus during antiviral therapy.
|
Hepatology
|
2009
|
1.05
|
119
|
Recombination increases human immunodeficiency virus fitness, but not necessarily diversity.
|
J Gen Virol
|
2008
|
1.05
|
120
|
Treatment response in acute/early infection versus advanced AIDS: equivalent first and second phases of HIV RNA decline.
|
AIDS
|
2008
|
1.05
|
121
|
Emergence of HIV-1 drug resistance during antiretroviral treatment.
|
Bull Math Biol
|
2007
|
1.05
|
122
|
High-potency human immunodeficiency virus vaccination leads to delayed and reduced CD8+ T-cell expansion but improved virus control.
|
J Virol
|
2005
|
1.05
|
123
|
Asymmetric division of activated latently infected cells may explain the decay kinetics of the HIV-1 latent reservoir and intermittent viral blips.
|
Math Biosci
|
2008
|
1.05
|
124
|
Precise determination of time to reach viral load set point after acute HIV-1 infection.
|
J Acquir Immune Defic Syndr
|
2012
|
1.05
|
125
|
Pharmacodynamics of antiretroviral agents in HIV-1 infected patients: using viral dynamic models that incorporate drug susceptibility and adherence.
|
J Pharmacokinet Pharmacodyn
|
2006
|
1.05
|
126
|
Dominance of the CD4(+) T helper cell response during acute resolving hepatitis A virus infection.
|
J Exp Med
|
2012
|
1.04
|
127
|
Hepatitis C viral kinetics with the nucleoside polymerase inhibitor mericitabine (RG7128).
|
Hepatology
|
2012
|
1.04
|
128
|
An accurate two-phase approximate solution to an acute viral infection model.
|
J Math Biol
|
2009
|
1.03
|
129
|
A signature in HIV-1 envelope leader peptide associated with transition from acute to chronic infection impacts envelope processing and infectivity.
|
PLoS One
|
2011
|
1.03
|
130
|
Treatment of hepatitis C virus infection with interferon and small molecule direct antivirals: viral kinetics and modeling.
|
Crit Rev Immunol
|
2010
|
1.02
|
131
|
Effect of 1918 PB1-F2 expression on influenza A virus infection kinetics.
|
PLoS Comput Biol
|
2011
|
1.02
|
132
|
Modeling deuterated glucose labeling of T-lymphocytes.
|
Bull Math Biol
|
2002
|
1.02
|
133
|
Predicting the impact of a nonsterilizing vaccine against human immunodeficiency virus.
|
J Virol
|
2004
|
1.01
|
134
|
The probability of HIV infection in a new host and its reduction with microbicides.
|
Math Biosci
|
2008
|
1.00
|
135
|
A hepatitis C viral kinetic model that allows for time-varying drug effectiveness.
|
Antivir Ther
|
2008
|
1.00
|
136
|
Dynamics of T cells and TCR excision circles differ after treatment of acute and chronic HIV infection.
|
J Immunol
|
2002
|
0.99
|
137
|
Some scaling principles for the immune system.
|
Immunol Cell Biol
|
2004
|
0.97
|
138
|
Modelling deuterium labelling of lymphocytes with temporal and/or kinetic heterogeneity.
|
J R Soc Interface
|
2012
|
0.97
|
139
|
Stochastic models of lymphocyte proliferation and death.
|
PLoS One
|
2010
|
0.96
|
140
|
Triple combination antiviral drug (TCAD) composed of amantadine, oseltamivir, and ribavirin impedes the selection of drug-resistant influenza A virus.
|
PLoS One
|
2011
|
0.95
|
141
|
Analysis of human immunodeficiency virus cytopathicity by using a new method for quantitating viral dynamics in cell culture.
|
J Virol
|
2005
|
0.95
|
142
|
Evaluation of multitype mathematical models for CFSE-labeling experiment data.
|
Bull Math Biol
|
2011
|
0.95
|
143
|
Modeling T cell proliferation and death in vitro based on labeling data: generalizations of the Smith-Martin cell cycle model.
|
Bull Math Biol
|
2007
|
0.95
|
144
|
Modeling within-host HIV-1 dynamics and the evolution of drug resistance: trade-offs between viral enzyme function and drug susceptibility.
|
J Theor Biol
|
2007
|
0.95
|
145
|
Modeling of influenza-specific CD8+ T cells during the primary response indicates that the spleen is a major source of effectors.
|
J Immunol
|
2011
|
0.95
|
146
|
The effects of thymic selection on the range of T cell cross-reactivity.
|
Eur J Immunol
|
2005
|
0.94
|
147
|
Analysis of hepatitis C viral kinetics during administration of two nucleotide analogues: sofosbuvir (GS-7977) and GS-0938.
|
Antivir Ther
|
2014
|
0.94
|
148
|
Virus dynamics and immune responses during treatment in patients coinfected with hepatitis C and HIV.
|
J Acquir Immune Defic Syndr
|
2004
|
0.94
|
149
|
Effects of aging on influenza virus infection dynamics.
|
J Virol
|
2014
|
0.94
|
150
|
Modeling the effects of vaccination on chronically infected HIV-positive patients.
|
J Acquir Immune Defic Syndr
|
2002
|
0.94
|
151
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