P A Clarke

Author PubWeight™ 45.79‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Kirsten ras mutations in patients with colorectal cancer: the 'RASCAL II' study. Br J Cancer 2001 5.36
2 Kirsten ras mutations in patients with colorectal cancer: the multicenter "RASCAL" study. J Natl Cancer Inst 1998 4.65
3 Phase I clinical and pharmacokinetic study of bcl-2 antisense oligonucleotide therapy in patients with non-Hodgkin's lymphoma. J Clin Oncol 2000 2.12
4 Inhibition of signal transduction by the Hsp90 inhibitor 17-allylamino-17-demethoxygeldanamycin results in cytostasis and apoptosis. Cancer Res 2001 1.86
5 Evaluation of the LMA Supreme in 100 non-paralysed patients. Anaesthesia 2009 1.85
6 Expression of gastrin in developing gastric adenocarcinoma. Br J Surg 2001 1.65
7 Personalized cancer medicine: molecular diagnostics, predictive biomarkers, and drug resistance. Clin Pharmacol Ther 2012 1.60
8 Gelatinase (MMP-2 and -9) expression in gastrointestinal malignancy. Br J Cancer 1998 1.53
9 Progress in the preclinical discovery and clinical development of class I and dual class I/IV phosphoinositide 3-kinase (PI3K) inhibitors. Curr Med Chem 2011 1.44
10 BCL-2 antisense therapy in patients with non-Hodgkin lymphoma. Lancet 1997 1.30
11 Silencing the cochaperone CDC37 destabilizes kinase clients and sensitizes cancer cells to HSP90 inhibitors. Oncogene 2008 1.24
12 Surprising specificity of PKR binding to delta agent genomic RNA. RNA 1997 1.12
13 De-regulation of the sonic hedgehog pathway in the InsGas mouse model of gastric carcinogenesis. Br J Cancer 2007 1.08
14 Apoptosis is associated with triacylglycerol accumulation in Jurkat T-cells. Br J Cancer 2002 1.03
15 The abrupt withdrawal of antiparkinsonian drugs in schizophrenic patients. Br J Psychiatry 1974 1.01
16 Preclinical antitumor activity and pharmacodynamic studies with the farnesyl protein transferase inhibitor R115777 in human breast cancer. Clin Cancer Res 2001 0.99
17 K-ras mutations in patients with early colorectal cancers. Gut 1997 0.99
18 Potential role of endocrine gastrin in the colonic adenoma carcinoma sequence. Br J Cancer 2002 0.98
19 Muscle fibre size in normal infants, children and adolescents. An autopsy study. J Neurol Sci 1971 0.94
20 Magnetic resonance detects metabolic changes associated with chemotherapy-induced apoptosis. Br J Cancer 1999 0.94
21 Expression of CCKB/gastrin receptor isoforms in gastro-intestinal tumour cells. Int J Cancer 1998 0.91
22 Bcl-2 expression and response to chemotherapy in colorectal adenocarcinomas. Br J Cancer 1997 0.86
23 Androgen receptors may act in a paracrine manner to regulate oesophageal adenocarcinoma growth. Eur J Surg Oncol 2007 0.86
24 The effect of calcium supplements on rectal mucosal proliferation. Br J Cancer 1995 0.80
25 Antiserum raised against an epitope of the cholecystokinin B/gastrin receptor inhibits hepatic invasion of a human colon tumor. Cancer Res 2000 0.80
26 Antisense treatment directed against mutated Ki-ras in human colorectal adenocarcinoma. Gut 2001 0.80
27 Pre-clinical evaluation of the Gastrimmune immunogen alone and in combination with 5-fluorouracil/leucovorin in a rat colorectal cancer model. Int J Cancer 1998 0.80
28 Inhibition of Kirsten-ras expression in human colorectal cancer using rationally selected Kirsten-ras antisense oligonucleotides. Mol Cancer Ther 2001 0.79
29 The carbenoid approach to peptide synthesis. Chemistry 2000 0.79
30 A comparison of an anti-gastrin antibody and cytotoxic drugs in the therapy of human gastric ascites in SCID mice. Int J Cancer 1999 0.79
31 Analytical methods for the determination of sterigmatocystin in cheese, bread and corn products using HPLC with atmospheric pressure ionization mass spectrometric detection. Food Addit Contam 1996 0.78
32 The identification of high and low risk groups for colorectal cancer using rectal mucosal crypt cell production rate (CCPR). Br J Cancer 1993 0.78
33 Individuals with a strong family history of colorectal cancer demonstrate abnormal rectal mucosal proliferation. Br J Surg 1993 0.77
34 Cell kinetics of the in vitro metaphase arrest technique and the clinical applications. Eur J Cancer Prev 1993 0.76
35 Surgical delivery of drug releasing poly(lactic-co-glycolic acid)/poly(ethylene glycol) paste with in vivo effects against glioblastoma. Ann R Coll Surg Engl 2014 0.75
36 Wheat fibre, lactulose and rectal mucosal proliferation in individuals with a family history of colorectal cancer. Br J Surg 1994 0.75
37 The General Practice computer system project: a doctor's desktop for Australia. Int J Med Inform 1999 0.75
38 Quantitative analysis of morphine in urine by gas chromatography-chemical ionization-mass spectrometry, with (N-C2H3)morphine as an internal standard. Clin Chem 1974 0.75
39 Determination of pyrrolizidine alkaloids in honey from selected sites by solid phase extraction and HPLC-MS. Food Addit Contam 1997 0.75
40 The National Joint Registry may fail to collect accurate, validated anaesthetic data. Anaesthesia 2009 0.75
41 A comparison of conventional and double contrast barium enemas. Clin Radiol 1973 0.75
42 DNA content of rectal mucosa and rectal mucosal proliferation in individuals at high risk of colorectal cancer. Eur J Cancer Prev 1994 0.75
43 Review of: "Grid Organization Development: A Systems Approach". By R. R. BLAKE and J. S. MOUTON. (Gulf Publishing Company, 1968.) [Pp. xv+374.] $10.00. Ergonomics 1969 0.75
44 Innovative cancer drug targets: genomics, transcriptomics and clinomics. Expert Opin Pharmacother 2001 0.75