Wolfgang Uckert

Author PubWeight™ 48.38‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Lethal graft-versus-host disease in mouse models of T cell receptor gene therapy. Nat Med 2010 2.92
2 T cells expressing a chimeric antigen receptor that binds hepatitis B virus envelope proteins control virus replication in mice. Gastroenterology 2013 1.77
3 Human antitumor CD8+ T cells producing Th1 polycytokines show superior antigen sensitivity and tumor recognition. J Immunol 2012 1.68
4 Misinitiation of intrathymic MART-1 transcription and biased TCR usage explain the high frequency of MART-1-specific T cells. Eur J Immunol 2014 1.59
5 The only proposed T-cell epitope derived from the TEL-AML1 translocation is not naturally processed. Blood 2011 1.56
6 T-cell receptor gene transfer exclusively to human CD8(+) cells enhances tumor cell killing. Blood 2012 1.55
7 Elimination of human leukemia cells in NOD/SCID mice by WT1-TCR gene-transduced human T cells. Blood 2005 1.51
8 Retroviral vectors for high-level transgene expression in T lymphocytes. Hum Gene Ther 2003 1.43
9 MHC-restricted fratricide of human lymphocytes expressing survivin-specific transgenic T cell receptors. J Clin Invest 2010 1.30
10 Enhanced functionality of T cell receptor-redirected T cells is defined by the transgene cassette. J Mol Med (Berl) 2008 1.28
11 Designer T cells by T cell receptor replacement. Eur J Immunol 2006 1.14
12 Minimal amino acid exchange in human TCR constant regions fosters improved function of TCR gene-modified T cells. J Immunol 2010 1.10
13 Dendritic cells pulsed with RNA encoding allogeneic MHC and antigen induce T cells with superior antitumor activity and higher TCR functional avidity. Blood 2009 1.10
14 Overexpression of NPM-ALK induces different types of malignant lymphomas in IL-9 transgenic mice. Oncogene 2003 1.07
15 A safeguard eliminates T cell receptor gene-modified autoreactive T cells after adoptive transfer. Proc Natl Acad Sci U S A 2008 1.06
16 TCR-transgenic lymphocytes specific for HMMR/Rhamm limit tumor outgrowth in vivo. Blood 2012 1.05
17 Do CARs need a driver's license? Adoptive cell therapy with chimeric antigen receptor-redirected T cells has caused serious adverse events. Hum Gene Ther 2010 1.04
18 TCR-ligand koff rate correlates with the protective capacity of antigen-specific CD8+ T cells for adoptive transfer. Sci Transl Med 2013 1.02
19 Dual T cell receptor T cells with two defined specificities mediate tumor suppression via both receptors. Eur J Immunol 2004 0.95
20 Redirecting T lymphocyte specificity by T cell receptor gene transfer--a new era for immunotherapy. Mol Aspects Med 2007 0.94
21 Targeting human melanoma neoantigens by T cell receptor gene therapy. J Clin Invest 2016 0.92
22 MHC multimer-guided and cell culture-independent isolation of functional T cell receptors from single cells facilitates TCR identification for immunotherapy. PLoS One 2013 0.92
23 T-cell receptor gene-modified T cells with shared renal cell carcinoma specificity for adoptive T-cell therapy. Clin Cancer Res 2010 0.91
24 Redirecting human T lymphocytes toward renal cell carcinoma specificity by retroviral transfer of T cell receptor genes. Hum Gene Ther 2005 0.91
25 The antitumorigenic response of neural precursors depends on subventricular proliferation and age. Stem Cells 2008 0.90
26 Dual T cell receptor expressing CD8+ T cells with tumor- and self-specificity can inhibit tumor growth without causing severe autoimmunity. J Immunol 2007 0.90
27 CD8alpha/alpha homodimers fail to function as co-receptor for a CD8-dependent TCR. Eur J Immunol 2007 0.88
28 Tumor rejection by local interferon gamma induction in established tumors is associated with blood vessel destruction and necrosis. Int J Cancer 2010 0.88
29 Non-physiological overexpression of the low density lipoprotein receptor (LDLr) gene in the liver induces pathological intracellular lipid and cholesterol storage. J Gene Med 2004 0.87
30 Enhanced T cell receptor gene therapy for cancer. Expert Opin Biol Ther 2010 0.86
31 Transmitter- and hormone-activated Ca(2+) responses in adult microglia/brain macrophages in situ recorded after viral transduction of a recombinant Ca(2+) sensor. Cell Calcium 2011 0.86
32 A single TCR alpha-chain with dominant peptide recognition in the allorestricted HER2/neu-specific T cell repertoire. J Immunol 2009 0.84
33 The tumor-associated antigen EBAG9 negatively regulates the cytolytic capacity of mouse CD8+ T cells. J Clin Invest 2009 0.84
34 Manufacture of gene-modified human T-cells with a memory stem/central memory phenotype. Hum Gene Ther Methods 2014 0.83
35 Plasticity in the contribution of T cell receptor variable region residues to binding of peptide-HLA-A2 complexes. J Mol Biol 2013 0.83
36 CY15, a malignant histiocytic tumor that is phenotypically similar to immature dendritic cells. Cancer Res 2005 0.83
37 Immunotherapy with TCR-redirected T cells: comparison of TCR-transduced and TCR-engineered hematopoietic stem cell-derived T cells. J Immunol 2013 0.81
38 Construction, rescue, and characterization of vectors derived from ovine atadenovirus. J Virol 2003 0.81
39 Transduction efficiency of MLV but not of HIV-1 vectors is pseudotype dependent on human primary T lymphocytes. J Mol Med (Berl) 2003 0.80
40 Neuroimmune crosstalk in asthma: dual role of the neurotrophin receptor p75NTR. J Allergy Clin Immunol 2007 0.79
41 NY-ESO-1 antigen-reactive T cell receptors exhibit diverse therapeutic capability. Int J Cancer 2012 0.78
42 HEK293-based production platform for γ-retroviral (self-inactivating) vectors: application for safe and efficient transfer of COL7A1 cDNA. Hum Gene Ther Clin Dev 2014 0.77
43 TCR-engineered T cells: a model of inducible TCR expression to dissect the interrelationship between two TCRs. Eur J Immunol 2013 0.77
44 Targeting high-grade B cell lymphoma with CD19-specific T cells. Int J Cancer 2014 0.76
45 Targeting the epidermal growth factor receptor (HER) family by T cell receptor gene-modified T lymphocytes. J Mol Med (Berl) 2010 0.76
46 Protective capacity of virus-specific T cell receptor-transduced CD8 T cells in vivo. J Virol 2012 0.75
47 Interleukin-9 (IL-9) and NPM-ALK each generate mast cell hyperplasia as single 'hit' and cooperate in producing a mastocytosis-like disease in mice. Oncotarget 2010 0.75
48 Identification of an ovine atadenovirus gene whose product activates the viral E2 promoter: possible involvement of E2F-1. Virology 2004 0.75